This study analyzed demographic differences and differential mortality between the Mississippi State Asylum (MSA) and the state of Mississippi. Using census records, Biennial Reports, death certificates, and vital statistics from the Mississippi State Board of Health, statistical methods including Kaplan-Meier survival analysis and Cox proportional hazard analysis were employed to explore significant differences in population demographics, hazard of death, and survivorship in general and with tuberculosis. Key results include proportionally more females in the MSA, increased hazard of death/decreased survivorship within the MSA compared to the State, and increased hazard of death/decreased survivorship for Black/AA individuals compared to their White/EA counterparts. This study demonstrates the intersectionality of sex, race, and institutionalization on survivorship and highlights the continued relevance of such issues in modern times, particularly regarding institutional treatment.

This research examines the relationship between growth, growth disruption, and skeletal indicators stress amongst juveniles (n=60) interred at the Late Antique infant and child cemetery at Poggio Gramignano (PG) (ca. 5th century CE), associated with a rural agricultural community. Growth disruption – evidenced by decreased long bone length compared to dental age – and stress experience – evidenced by skeletal stress indicators – were compared to those within juveniles from two urban Roman-era cemeteries (n=66), Villa Rustica (VR) (0-400 CE) and Tragurium City Necropolis (TCN) (400-700 CE). Results indicate that the PG juveniles had significantly smaller femoral lengths-for-age than VR and TCN; however, the frequency of skeletal stress indicators were higher among juveniles at VR and TCN. These differences in growth and stress experience likely resulted from differing biosocial and ecological environments present in the different regions at the time, including differing nutrition, disease, and socioeconomic structures between urban and rural Roman populations.

Femoral and tibial diaphyseal geometry has frequently been used to evaluate mobility and other patterns of physical activity in past populations. The high antero-posterior (A-P) to medio-lateral (M-L) bending rigidity ratio (IX/IY) typical of many hunter-gatherer femora, for instance, may reflect mechanical loads associated with long distance travel. The possible confounding effect of physical terrain on lower limb diaphyseal morphology is rarely evaluated. This study investigated the possible effect of terrain on lower limb shape ratios (IX/IY) and bending and torsional strength (ZP) in adult skeletons from Europe, North America, Africa, and Asia, covering a time span from around 30,000 BP to the present. Midshaft femoral and tibial cross-sectional geometric properties for 3515 individuals were gathered from databases kindly provided by researchers. Geographic coordinates were found for each archaeological site. Local terrain for each site was quantified with ArcGIS 10 mapping software using USGS elevation data, and characterized as flat, hilly, or mountainous. Analysis of variance shows significant differences (pP) of both femoral and tibial midshaft among the three terrain categories, with more A-P oriented diaphyseal shapes and greater strength in hilly and mountainous groups, even after correcting for the effect of subsistence on these cross-sectional properties. These results suggest that terrain needs to be taken into account in analyses of lower limb diaphyseal structure and mobility. Latitude and coastal proximity were also investigated as possible biogeographic factors in the morphology of lower limb diaphyses.

Although stable isotope analysis is routinely utilized in bioarchaeology and relies on principles that are well-understood, there are still fundamental issues that have not been thoroughly investigated. This thesis examines the relationship between inter-tissue spacing of carbon stable isotope values (δ13C) and age in juvenile human remains. Analyses of tissues within the same individual reveal disparate isotopic values for a variety of physiological and biological reasons discussed herein. This project examines the distance between the δ13C values in bone collagen, skin, hair, and nail, and examines how these distances vary between different age groups, utilizing data collected from 52 well-preserved human remains from the Dakhleh Oasis, Egypt: 28 individuals between the ages of 1 and 4 years, 14 between 5 and 10 years, and 10 between the ages of 11-15 years. The mean carbon isotope values for each tissue were compared across each age group, and used to calculate the differences between each tissue type. Although distances between tissues were found to vary across all age categories, the distances between collagen and hair, collagen and skin, and collagen and nail are all substantially greater in the 11-15 year old category than those in the 1-4 and 5-10 year categories. Possible physiological, developmental and social factors are discussed in an effort to explain this discrepancy

Females of childbearing age are overrepresented in the population of the Kellis 2 cemetery (100-450 AD) in the Dakhleh Oasis, Egypt (Wheeler 2009). The demographic overrepresentation found here may be the result of complications related to childbirth. Clinical literature demonstrates that fetal size is rarely an explanation for failed labor (Cunningham et al. 2001) and the fetuses buried in the Kellis 2 Cemetery at the Dakhleh Oasis were not larger than average (Tocheri et al. 2005), directing the focus to dimensions of the maternal pelvis for evidence of obstetrical issues, such as abnormally compressed pelvises. To formulate a test for this hypothesis, a total of 50 adults, 24 of which are female, were examined for this study. The sample consisted of individuals from an archaeological population from the Dakhleh Oasis, Egypt as well as from six populations housed in the American Museum of Natural History (NYC). These include archaeological populations from the sites of El Hesa and Sai Island in the Sudan, also South Africa, Nubia, and India, as well as a medical collection from North America. Pelvic dimension and asymmetry was determined through nine measurements of the pelvis and sacrum. Kruskal-Wallis tests were used to analyze variance and assess whether the younger females in this group may have been at a higher risk of death during childbirth due to fetal-pelvic disproportion. Mann-Whitney-Wilcoxan nonparametric tests were used to assess differences in asymmetry in young and old groups. A MANOVA test assessed overall variation in the population. Results indicate significant differences between young and old females in pelvic outlet anteroposterior diameter, a measure of midpelvic contraction, as young females had smaller pelvic outlet anteroposterior diameters. There were also significant differences between iv young and old females in alar-pubis length asymmetry; the young females were more asymmetric. These differences were not found in the male groups. It is suggested that these differences could impact childbirth as a contracted midpelvis, such as that found in the young female group, can cause transverse arrest of the fetal head (Cunningham et al. 2010) and pelvic asymmetry can contribute to obstetrical complications (Campbell et al. 2011).

The skeletal remains in this study were excavated from the Nubian archaeological island fortress site of Askut (ca. 1850 BC - 1070 BC, New Kingdom/Third Intermediate period), located at the 2nd Cataract of the Nile river in Sudan. These remains were recovered as part of an archaeological expedition from 1962-1964, which was an effort to learn as much as possible about this site before the building of the High Dam in Aswan. Seven fetal skeletons (dated ca. 1260-770 BC) were examined for their biocultural significance. Biological analysis of these individuals indicates a range in developmental age from 36 to 40 weeks gestation. Three of the seven individuals show signs of pathology, including vertebral lesions, a deformed sphenoid, and cranial infectious bone reaction. These individuals, all interred in ceramic pots, were excavated from the pomoerium (the religious/sacred boundary or symbolic wall) of Askut's fortress. The interment style and burial location indicate that these individuals were treated differently in comparison to the children and adults of Askut, who were most likely buried in the cemeteries along the banks of the Nile. As Nubia was an Egyptian colony at this point in history, Egyptian influences and ideology would have had a large impact on Nubian culture, and this is reflected in the burial treatment of these individuals. Biocultural analyses of these individuals are used to interpret the particular burial patterns of these individuals.

A juvenile’s dependency on their caregiver is significant to the overall development of nutritionally related pathological lesions. However, not all skeletal pathology is caused by nutritional stress; despite anemia being the usual inferred cause, the origin of Cribra Orbitalia (CO) – lesions on the orbital roofs of the cranium– is undetermined. The purpose of this research is to compare the reconstructed diets of juveniles with and without CO and explore connections to dietary patterns (inferred from stable isotope ratios of carbon and nitrogen). Rib bone samples of 79 juveniles with and without CO were sampled from the Kuelap archaeological site in Chachapoyas, Peru (AD 800–1532) – known for its archaeological diversity. Stable isotope analysis was conducted (δ13C and δ15N values) to statistically analyze each group’s values. Samples were further subdivided into age cohorts of infants (0–3 years), juveniles (4–11 years), and adolescents (12–18 years). The diets of juveniles with and without CO were determined to have no statistically significant difference between each other. However, a significant statistical difference did exist between the diets of the different juvenile age cohorts regardless of CO status, indicating that weaning and early dietary transitions through childhood affected the juvenile’s nutritional regime in the region. The research presented is the first study of the relationship between nutrition and CO from Kuelap; significantly, it further explores the lifestyle of past individuals in Chachapoyas through the understanding of childhood diets.

Disease is not a unique or singular phenomenon. The medical literature contains multiple reports discussing disease interactions and co-occurrence which remains an important issue. Despite this, there has been no systematic investigation of disease co-occurrence in paleopathology. This thesis will begin to fill the gap by producing a detailed analysis of the pathological indicators for scurvy, rickets, and their co-occurrence, focussing on features of co-occurrence and their identification. The Collégiale Saint-Amé collection from 16th to 18th century Douai, France includes 48 individuals ranging from fetal to five years of age. Previous research indicated a large number of potential cases of scurvy and rickets in the juveniles (Devriendt et al. 2010). The current study identified 12 cases of possible co-occurrence based on macroscopic, radiographic, and microscopic techniques; biocultural and historical data supported disease presence. Macroscopic results indicate that lesions associated with scurvy are identifiable and the vascular system is not known to be directly affected by rickets. Rickets features are present but changes are subtle and reduced in prevalence. Radiographs demonstrate features of both diseases but the presence or absence of the line of Fraenkel, a scurvy feature, was useful in identifying the likely dominant disease process. Diagenetic change significantly impacted microscopic investigations but the technique provided some supporting evidence for the presence of rickets. The results clearly demonstrate that cases of co-occurrence of scurvy and rickets are present and identifiable in the archaeological record. Important factors for recognition include the sequence in which conditions develop and duration of illness. Presently only cases with moderately or better developed features of both scurvy and rickets can be identified. Use of multiple techniques was critical to observe subtle changes and build a case for disease presence. Further research on co-occurrence of any diseases is encouraged to create a fuller understanding of past disease. / Thesis / Master of Arts (MA)

Morphological integration refers to the interdependence of two or more phenotypic structures. The morphological integration concept is based on the fact that parts of complex organisms do not vary randomly and instead display degrees of non-independence that are thought to occur from shared genetic or developmental origins, and/or functional demands. Integrated traits may develop, evolve, and be inherited together. One instance of morphological integration can be found between the vertebral column and the skull. Due to the position of the skull resting atop of the vertebral column, posture may influence skull development and overall craniofacial morphology. Morphological integration within or between structures is typically statistically assessed by exploring correlation and covariation patterns among biological structures of interest. In this study, an analysis of morphological integration was carried out by studying covariation of morphometric measures from the vertebral column and craniofacial complex. Age- and sex-matched, de-identified computed tomography images of individuals with kyphosis spinal malformation (n = 15) and controls (n = 19) were acquired from Florida Hospital. It is hypothesized that the sample of individuals with kyphosis will exhibit statistically significant covariance differences relative to the control group for T6 vertebral and midfacial linear distance measurements. Anatomical landmarks were identified on the T6 thoracic vertebrae (n = 6) and the midfacial skeleton (n = 6), and XYZ coordinates were recorded for analysis. A subset of 10 individuals (5 kyphosis, 5 controls) individuals were measured on two occasions to assess reliability and measurement error. An Euclidean Distance Matrix Analysis (EDMA) of morphological integration was carried out on the entire sample by calculating correlation values for paired linear distance measurements (one vertebral and one midfacial) separately for the kyphosis and control samples (n = 225 for each sample). Next, EDMA calculated correlation differences and statistically assessed significance using a non-parametric bootstrap (1,000 resamples) and confidence interval testing (α ≤ 0.10). Only 35 of the 225 (15.56%) correlation differences were statistically significant. Patterns of variation among these significant correlation differences were explored by examining sample directionality of differences, sign patterns, and strengths. The relevance of these results to clinical and anthropological pursuits are discussed. Several recommendations for future investigations are made.

The discovery of 5,500 Homo heidelbergensis fossil specimens at the Sima de los Huesos archaeological site in Spain has opened up the opportunity for research to be conducted on the vocal capabilities of this species. Previous research has revealed that the range of vowel sounds an individual can produce, known as the vowel space, is directly affected by the dimensions of the vocal tract. The vowel spaces of two hominins, Homo sapiens and Homo neanderthalensis, have been reconstructed through previous research. However, the vowel space of Homo heidelbergensis has not yet been reconstructed. In this research, I aim to explore how the dimensions of the Homo heidelbergensis vocal tract affect the vowel space of that species. This was pursued by measuring the craniospinal dimensions of five Homo heidelbergensis specimens through three dimensional imaging software. When measurements were unattainable due to limitations in the fossil record, regression equations were used to predict missing measurements. By doing so, the vowel space of this species was reconstructed, and crucial information into the vocal capabilities of this close human ancestor was revealed.