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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
51

Contingency and context in the relationships of female vervet monkeys

Forshaw, Nicola L January 2011 (has links)
This study explored the organizing principles of female sociality in free-ranging vervet monkeys (Chlorocebus aethiops) inhabiting the Klein Karoo, South Africa. Females groomed more than males, grooming peaked at the end of the day and less grooming occurred during the mating season. Although females competed over food, they did not compete over grooming partners, rarely formed coalitions and did not trade grooming against other activities. Instead, they maintained grooming whilst trading between feeding and resting and feeding and moving. Despite seasonal shifts in food competition, grooming was not traded for tolerance and there was an upper limit to cohort size before clique size declined. Inter-population comparisons revealed no troop size effects on clique size, aggression and competition over high-ranking grooming partners. The rarity of coalitions suggests coalitions are unlikely to be a central component of female relationships. / xiii, 162 leaves : ill., maps ; 29 cm
52

Features of catarrhine posterior dental crowns associated with durophagy: Implications for fossil hominins

O'Hara, Mackie Clare January 2021 (has links)
No description available.
53

Dispersion of large-seeded tree species by two forest primates: primate seed handling, microhabitat variability, and post-dispersal seed fate

Gross-Camp, Nicole D. 02 February 2009 (has links)
No description available.
54

Agonist-induced PKC phosphorylation regulates GluK2 SUMOylation and kainate receptor endocytosis

Konopacki, F.A., Jaafari, N., Rocca, D.L., Wilkinson, K.A., Chamberlain, S.E., Rubin, P., Kantamneni, Sriharsha, Mellor, J.R., Henley, J.M. January 2011 (has links)
No / The surface expression and regulated endocytosis of kainate (KA) receptors (KARs) plays a critical role in neuronal function. PKC can modulate KAR trafficking, but the sites of action and molecular consequences have not been fully characterized. Small ubiquitin-like modifier (SUMO) modification of the KAR subunit GluK2 mediates agonist-evoked internalization, but how KAR activation leads to GluK2 SUMOylation is unclear. Here we show that KA stimulation causes rapid phosphorylation of GluK2 by PKC, and that PKC activation increases GluK2 SUMOylation both in vitro and in neurons. The intracellular C-terminal domain of GluK2 contains two predicted PKC phosphorylation sites, S846 and S868, both of which are phosphorylated in response to KA. Phosphomimetic mutagenesis of S868 increased GluK2 SUMOylation, and mutation of S868 to a nonphosphorylatable alanine prevented KA-induced SUMOylation and endocytosis in neurons. Infusion of SUMO-1 dramatically reduced KAR-mediated currents in HEK293 cells expressing WT GluK2 or nonphosphorylatable S846A mutant, but had no effect on currents mediated by the S868A mutant. These data demonstrate that agonist activation of GluK2 promotes PKC-dependent phosphorylation of S846 and S868, but that only S868 phosphorylation is required to enhance GluK2 SUMOylation and promote endocytosis. Thus, direct phosphorylation by PKC and GluK2 SUMOylation are intimately linked in regulating the surface expression and function of GluK2-containing KARs.
55

Dietary flavonoid (-)epicatechin stimulates phosphatidylinositol 3-kinase-dependent anti-oxidant response element activity and up-regulates glutathione in cortical astrocytes

Bahia, P.K., Rattray, Marcus, Williams, R.J. 09 1900 (has links)
No / Flavonoids are plant-derived polyphenolic compounds with neuroprotective properties. Recent work suggests that, in addition to acting as hydrogen donors, they activate protective signalling pathways. The anti-oxidant response element (ARE) promotes the expression of protective proteins including those required for glutathione synthesis (xCT cystine antiporter, gamma-glutamylcysteine synthetase and glutathione synthase). The use of a luciferase reporter (ARE-luc) assay showed that the dietary flavan-3-ol (-)epicatechin activates this pathway in primary cortical astrocytes but not neurones. We also examined the distribution of NF-E2-related factor-2 (Nrf2), a key transcription factor in ARE-mediated gene expression. We found, using immunocytochemistry, that Nrf2 accumulated in the nuclei of astrocytes following exposure to tert-butylhydroquinone (100 microM) and (-)epicatechin (100 nM). (-)Epicatechin signalling via Nrf2 was inhibited by wortmannin implicating a phosphatidylinositol 3-kinase-dependent pathway. Finally, (-)epicatechin increased glutathione levels in astrocytes consistent with an up-regulation of ARE-mediated gene expression. Together, this suggests that flavonoids may be cytoprotective by increasing anti-oxidant gene expression.
56

A Conservation Genetic Study of Cercopithecus mitis in the Lomami Basin, Democratic Republic of the Congo

Unknown Date (has links)
The Cercopithecus mitis radiation has significant phenotypic and ecological diversity, making it a great candidate for evolutionary genetic studies. This study represents the first genetic survey of C. mitis from well provenanced wild populations, including C. mitis heymansi from the TL2 landscape, an area of remote tropical forest between the Tshuapa, Lomami, and Lualaba rivers in the Democratic Republic of the Congo. Tissue samples were collected from 7 male blue monkeys, DNA was extracted and surveyed at 919 bp of the Testis-Specific Protein Y-chromosome (TSPY), and added to a larger dataset including other C. mitis and C. albogularis specimens. Evolutionary analyses suggests TL2 C. mitis shared recent genetic contact with C. albogularis at the headwaters of the Congo River than with conspecifics to the northeast, indicating the Congo River is a significant biogeographic barrier to C. mitis and sheds new light on their genetic heritage, taxonomic assignment, and conservation status. / Includes bibliography. / Thesis (M.A.)--Florida Atlantic University, 2016. / FAU Electronic Theses and Dissertations Collection

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