Title: Measurement of lower extremities spasticity in patients with cerebral palsy Objectives: The aim of the theoretical part of this thesis is to evaluate possibilities of lower extremities spasticity measurement in adult patients with cerebral palsy. The main focus was given to the concept of French professor J.-M. Gracies: Five- step clinical assessment in spastic paresis. This unique concept presents differentiation of three main factors of motor impairment that emerge as a result of a lesion to central motor pathways: stretch sensitive paresis, soft tissue contracture and muscle overactivity. Ability to distinguish these factors is crucial for specific treatment indication. Finding a correlation between the Five-step clinical assessment in spastic paresis and muscle activity in gait measured with polyEMG was the main objective in the practical part of the thesis. Methodology: This thesis has a theoretical-empirical character. The theoretical part is in a form of a research on the topic of spasticity diagnosis, focused on cerebral palsy patients. The empirical part of the thesis has a form of pilot quantitative research, which was attended by 6 participants with cerebral palsy (4 men and 2 women; average age 29 years). There were 2 independent measurement made for each of them. Each...

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Using the right method of evaluation for clinical competence in nursing education plays a major role in obtaining appropriate results and making correct judgements. Nurse educators favour the Objective Structured Clinical Assessment (OSCA) for this purpose. The objective of this study was two-fold; firstly to explore and describe the experiences of nurse educators and student nurses of the OSCA within a private nursing college in Gauteng. The second objective was to develop implementation guidelines for the use of the OSCA as an assessment method. A qualitative, exploratory, descriptive, and contextual design was used and employed individual in-depth interviews, as well as field and direct observations to collect data. A purposive sampling method was used to select participants for the study and the sample comprised of ten nurse educators and ten student nurses to represent the population. Data were analysed thematically and resulted in seven themes and eighteen categories relating to nurse educators’ and student nurses’ experiences of the OSCA. Nurse educators had a predominantly negative view of the OSCA as an assessment method related to the ability of the OSCA to assess all learning assessment method related to the ability of the OSCA to assess all learning domains, the quality, structure, and organisation of the assessment, the simulated nature of OSCA, the availability of resources, as well as the feedback, communication and remedial action during the process. Challenges were experienced with the assessment tools as well as the educator as instrument. Educators raised a concern regarding the students’ readiness for evaluation. Student nurses related their experiences prior to the OSCA, their experiences of the educator, the structure and organisation of the OSCA, and their experience related to the communication and feedback of the results. Students related mixed emotional experiences as recipients of the assessment, as well as the relevance and benefits of the OSCA / Health Studies / M.A. (Nursing Education)

Introduction : Chez les jeunes enfants (<6 ans), la prise en charge de l’asthme est évaluée cliniquement. Dans certains centres, l’oscillométrie (OS) est utilisée en complément de l’évaluation clinique, mais son utilité clinique reste à quantifier. Objectifs : Déterminer si l’ajout de l’OS à l’évaluation clinique influence l’évaluation, la gestion et le contrôle de l’asthme, par rapport à l’évaluation clinique seule chez les jeunes enfants. Méthodes : Étude transversale portant sur des enfants de 3-5 ans avec un diagnostic d’asthme. Les enfants testés par l’OS étaient appariés par score de propension aux témoins (non testés). La probabilité d’un phénotype persistant et d’une prescription d’un traitement d’entretien (co- variables principales) était évaluée par régression logistique multivariée. Dans la cohorte rétrospective imbriquée avec accès aux données pharmaceutiques, le contrôle de l’asthme au cours de l’année suivante était examiné par régression logistique cumulative. Résultats : L’étude comprenait 726 enfants appariés (249 testés; 477 témoins) dont 57,4% garçons (âge médian: 4,62 ans) avec groupes relativement comparables. Les enfants testés recevaient plus souvent un phénotype persistant (67% vs. 50%; RC-ajusté [IC 95%]: 2,34 [1,66- 3,34]), sans différence significative dans la prescription d’un traitement d’entretien (65% vs. 58%; 1,37 [0,98-1,92]) et étaient moins susceptibles d’être incontrôlés dans l’année suivante (0,24 [0,08- 0,74]). Conclusion : L’association entre l’OS ajouté à l’évaluation clinique et à la fois plus de phénotypes persistants et un meilleur contrôle de l’asthme supporte l’utilité clinique de l’OS, possiblement via une reconnaissance accrue de l’obstruction des voies aériennes. / Background: In preschoolers (<6 years), asthma management is usually assessed clinically. In certain centres, oscillometry (OS) is used in adjunct to clinical assessment, yet its clinical utility remains to be quantified. Objectives: To determine if OS use, as an adjunct to clinical assessment, is associated with better asthma assessment, management and control compared to clinical assessment alone in preschoolers. Methods: A cross-sectional study of children aged 3-5 years with an asthma diagnosis. OS-tested preschoolers were matched by propensity score to controls (untested). The likelihood of persistent phenotype and maintenance therapy prescription (co-primary outcomes) were evaluated by multivariate logistic regression. In a nested retrospective cohort with available drug claim data, asthma control over the next year was examined by cumulative logistic regression. Results: The study comprised 726 matched children (249 OS-tested; 477 untested) of which 57.4% were boys (median age: 4.62 years) with comparable group characteristics. OS-tested children were more frequently labelled as persistent phenotype (67% vs. 50%; adjusted-OR[95% CI]: 2.34 [1.66- 3.34]), with no significant difference in prescription of maintenance therapy (65% vs. 58%; adjusted-OR[95% CI]: 1.37 [0.98-1.92]) and were less likely to be uncontrolled in the following year (adjusted-OR[95% CI]: 0.24 [0.08-0.74]). Conclusions: The association between OS added to clinical assessment with more persistent phenotype and better asthma control supports its clinical utility, possibly by increased recognition of airway obstruction at the index visit.

Title: Measurement of lower extremities spasticity in patients with cerebral palsy Objectives: The aim of the theoretical part of this thesis is to evaluate possibilities of lower extremities spasticity measurement in adult patients with cerebral palsy. The main focus was given to the concept of French professor J.-M. Gracies: Five-step clinical assessment in spastic paresis. This unique concept presents differentiation of three main factors of motor impairment that emerge as a result of a lesion to central motor pathways: stretch sensitive paresis, soft tissue contracture and muscle overactivity. Ability to distinguish these factors is crucial for specific treatment indication. Finding a correlation between the Five-step clinical assessment in spastic paresis and muscle activity in gait measured with sEMG was the main objective in the practical part of the thesis. Methodology: This thesis has a theoretical-empirical character. The theoretical part is in a form of a research on the topic of spasticity diagnosis, focused on cerebral palsy patients. The empirical part of the thesis has a form of pilot quantitative research, which was attended by 6 participants with cerebral palsy (4 men and 2 women; average age 29 years). There were 2 independent measurement made for each of them. Each measurement...

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El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado. / Background: In 1999, The International Study of Asthma and Allergies in Childhood (ISAAC) Phase One reported the prevalence of eczema symptoms in 715,033 children from 154 centers in 56 countries by using standardized epidemiologic tools. Objective: To update the world map of eczema prevalence after 5 to 10 years (ISAAC Phase Three) and include additional data from over 100 new centers. Methods: Cross-sectional surveys using the ISAAC questionnaire on eczema symptoms were completed by adolescents 13 to 14 years old and by parents of children 6 to 7 years old. Current eczema was defined as an itchy flexural rash in the past 12 months and was considered severe eczema if associated with 1 or more nights per week of sleep disturbance. Results: For the age group 6 to 7 years, data on 385,853 participants from 143 centers in 60 countries showed that the prevalence of current eczema ranged from 0.9% in India to 22.5% in Ecuador, with new data showing high values in Asia and Latin America. For the age group 13 to 14 years, data on 663,256 participants from 230 centers in 96 countries showed prevalence values ranging from 0.2% in China to 24.6% in Columbia with the highest values in Africa and Latin America. Current eczema was lower for boys than girls (odds ratio, 0.94 and 0.72 at ages 6 to 7 years and 13 to 14 years, respectively). Conclusion:ISAAC Phase Three provides comprehensive global data on the prevalence of eczema symptoms that is essential for public health planning. New data reveal that eczema is a disease of developing as well as developed countries. / Revisión por pares