Objective: To develop a score for hematoma expansion prediction, identify predictors of outcome, and validated existing prognostic scores in acute intracerebral hemorrhage (ICH). Methods: Data were obtained from a prospective multicenter ICH cohort. Patients were evaluated with computed tomography (CT) angiography, 24-hour CT, and 3-month outcome. Multivariable regression identified predictors of 24-hour expansion and 3-month outcome and a score was developed for expansion prediction. Existing scores were evaluated in the dataset. Results: The PREDICT Hematoma Expansion Score predicts 24-hour expansion based on number of spots, stroke severity, time from onset, and coagulopathy (c-statistic: 0.803). Prediction was improved over spot sign presence (p<0.001) and clinical variables alone (p=0.002). Existing scores for hematoma expansion and clinical outcome demonstrated reduced discrimination compared with the original reports. Conclusion: The PREDICT Hematoma Expansion Score may aid patient selection for future interventions aimed at reducing expansion however external validation is required. Existing scores demonstrated reduced discrimination.

Objective: To develop a score for hematoma expansion prediction, identify predictors of outcome, and validated existing prognostic scores in acute intracerebral hemorrhage (ICH). Methods: Data were obtained from a prospective multicenter ICH cohort. Patients were evaluated with computed tomography (CT) angiography, 24-hour CT, and 3-month outcome. Multivariable regression identified predictors of 24-hour expansion and 3-month outcome and a score was developed for expansion prediction. Existing scores were evaluated in the dataset. Results: The PREDICT Hematoma Expansion Score predicts 24-hour expansion based on number of spots, stroke severity, time from onset, and coagulopathy (c-statistic: 0.803). Prediction was improved over spot sign presence (p<0.001) and clinical variables alone (p=0.002). Existing scores for hematoma expansion and clinical outcome demonstrated reduced discrimination compared with the original reports. Conclusion: The PREDICT Hematoma Expansion Score may aid patient selection for future interventions aimed at reducing expansion however external validation is required. Existing scores demonstrated reduced discrimination.

Several computer-aided diagnostic (CAD) methods for solitary pulmonary nodules (SPNs) have been proposed, which can be divided into two major categories: (1) the morphometric CT method, and (2) the perfusion CT method. The first goal of this work is to introduce a neural network-based CAD method of lung nodule diagnosis by combining morphometry and perfusion characteristics by perfusion CT. The proposed approach has the following distinctive features. Firstly, this work develops a very efficient semi-automatic procedure to segment entire nodules. Secondly, reliable nodule classification can be achieved by using only two time-point perfusion CT feature measures (precontrast and 90 s). This greatly reduces the amount of radiation exposure to patients and the data processing time. As demonstrated in previous work, classification tuberculomas from malignancies has been considered to be a challenging task. However the diagnosis accuracy for tuberculomas reaches 92.9% by applying the proposed CAD method. Another goal of this work is, by investigating the relative merits of 2D and 3D methods, to develop a two-stage approach that combines the simplicity of 2D and the accuracy of 3D methods. Experimental results show statistically significant differences between the diagnostic accuracy of 2D and 3D methods. The results also show that with a very minor drop in diagnostic performance the two-stage approach can significantly reduce the number of nodules needed to be processed by the 3D method and thus alleviates the computational demand.

This work concerns / deals with theoretical analysis, design and implementation of system for creation three-dimensional computer models of human body tissues. These models will be created by computer tomography (CT) and magnetic resonance (MR) data. Output of medical apparatuses based on these principles is a three-dimensional raster, which is not good for visualization and making real models. For required tissues extraction are used automatic or semiautomatic methods, where is necessary an operation of a specialist. This work is concerned with human body tissues with linear structure such as veins and arteries, nerves, bone canals etc. These structures are problematic recognizable by automatic methods. Therefore is convenient an operation of a specialist, which is adept in human anatomy.

Yes / Rugby Union and Rugby League are popular sports with high participation across the world. The high impact nature of the sport results in a high proportion of injuries. Rugby has an association with cervical spine injury which has potentially catastrophic consequences for the patient. Anecdotal evidence suggests that radiographers find it challenging to visualise the cervicothoracic junction on the lateral supine cervical spine projection in broad shouldered athletes. This paper intends to analyse the risk factors for cervical spine injuries in rugby and discuss the imaging strategy in respect to radiography and CT scanning in high risk patient groups such as rugby players who are suspected of suffering a cervical spine injury.

Personal är utsatt för spridd strålning när de måste närvara vid CT trauman. Ögat är känsligt för joniserande strålning och det är bevisat att katarakt och strålning har ett samband. Vid CT-multitrauma används många projektioner och långa exponeringar. Studiens syfte är att undersöka hur mycket spridd strålning som personal utsätts för. Hur många gånger/år kan samma personal stå med innan rekommendationerna från ICRP på 20 mSv/år är uppnådd? Det är en kvantitativ studie som utförts empiriskt på två sjukhus med ett fantom. En Siemens 128 slice och en Toshiba 80 slice har använts vid mätningarna. Ett traumaprotokoll användes och en testmätning gjordes och därefter de riktiga mätningarna med dosimetrar från Landauer, placerade på sju mätpunkter i ögonhöjd på olika avstånd från gantryt. Den spridda strålningen var högst närmast gantryt och avtog med avståndet förutom två punkter som hade lägre mätresultat och kan förklaras på grund av dess vinkel från gantryt. Röntgensjuksköterskans ansvar är att informera om var personal bäst kan stå med vid CT trauman och att informera om vikten att variera personal. / Staff who has to attend CT-trauma examination is exposed to scattered radiation. The eye is sensitive to ionizing radiation and there is evidence that cataract and radiation are correlated. At CT-multitrauma long exposures and many projections is taken. The purpose of this study is to examine how much scattered radiation the staff is exposed to. How many times/year can one person in the staff attend a CT-trauma-examination before the ICRP recommendation dose of 20 mSv/year is reached? It is a quantitative study that has been done empirically at two hospitals with a phantom. A Siemens 128 slice and a Toshiba 80 slice were used in the measurements. A trauma protocol was used. One test measurement was done before the real measurements with dosimeters from Landuer placed at seven measure points at eye level at different distances from the gantry. The scattered radiation was highest close to the gantry and decreased with the distance except from two points that had lower measure results and this can be explained by the angle between the gantry and the dosimeter. It’s the radiographer’s responsibility to inform staff of the best place to stand at CT-trauma-examinations and to inform of the importance of alternating staff.

O objetivo do trabalho foi avaliar as alterações morfológicas bi, tridimensionais, e o transporte em canais mesiais de molares inferiores com curvatura acentuada. Selecionou-se molares inferiores com dois canais e forames independentes, livres de nódulos pulpares, reabsorção interna, tratamento endodôntico prévio, fratura radicular e dentro do padrão de raio e ângulo de curvatura, avaliados pelos exames radiográficos, tomográficos cone bean e microtomográficos. Partiu-se de 393 dentes para selecionar 15 dentro deste padrão morfológico. Esses dentes foram submetidos à microtomografia antes da instrumentação, após o preparo com instrumento Reciproc® R25 e após o preparo por cada lima dos sistemas de complementação (Mtwo e K3). Os dados morfométricos foram analisados pelo programa CTAn e as análises estatísticas foram realizadas utilizando o programa SPSS onde observou-se os seguintes resultados: a análise morfométrica bidimensional mostrou que a área e o perímetro apresentaram aumento gradual a cada milímetro avaliado, partindo do primeiro milímetro apical; houve também aumento gradual de área e de perímetro a cada troca de instrumento de acordo com o que se realizou o preparo biomecânico dentro dos conjuntos de grupos; houve diferença estatisticamente significante de área e de perímetro dos canais radiculares apenas após o preparo com os instrumentos #40 taper 04 e taper 02 (P<0,05). Em relação à distância do ápice, houve diferença estatística de área entre todos os milímetros avaliados (P<0,05). Em relação ao perímetro, não houve diferença entre os milímetros 1 e 2; e, 4 e 5 (P>0,05), entretanto com diferença entre o terceiro milímetro e os demais (P<0,05). As análises morfológicas tridimensionais de volume, área de superfície e SMI (Índice de Modelo Estrutural) do canal radicular, tiveram comportamento semelhante entre os grupos. Os espécimes submetidos à complementação, com instrumentos taper 04 e taper 02, não apresentaram diferença estatística após os preparos (P>0,05), com diferença entre os canais preparados com a R25 e os canais originais (P<0,05). Quando comparados os conjuntos de grupos, nenhum grupo análogo apresentou diferença estatística (P>0,05). Foi analisado o transporte por terços (cervical, médio e apical) e por todo o canal, não sendo detectada diferença estatisticamente significante (P>0,05) entre os terços, nem do canal todo entre a complementação pelos instrumentos taper 04 (Mtwo) e taper 02 (K3). / The purpose of this study was to evaluate the two- and three-dimensional morphological changes, and the transportation that occurs in the mesial canals of mandibular molars with severe curvature. Molars were selected with two independent canals and foramina, no pulpal nodules, internal resorptions, previous endodontic treatment or root fracture and within the standard radius and angle of curvature evaluated by radiographs, cone-beam tomography and microtomography. From the 393 teeth initially selected, 15 fulfilled the selected parameters. The teeth were subjected to microtomography before instrumentation, after instrumentation with Reciproc® R25 and after preparation with each file of the complementary systems (MTwo and K3). The morphometric data were analyzed by CTAn software and the statistical analysis was performed using the SPSS software where the following results were observed. The two-dimensional morphometric analysis showed that the area and the perimeter presented a gradual increase for every evaluated millimeter, starting from the first apical millimeter. There was also a gradual increase in area and perimeter with each change of instrument according to the biomechanical within the sets of groups. There was a statistically significant difference in area and perimeter of root canals after the preparation with the instruments #40 taper 04 and taper 02 (P <0.05). Regarding the distance from the apex area, there was statistically difference among all evaluated millimeters (P <0.05). Regarding the perimeter, there was no difference between 1 and 2 mm, and 4 or 5 (P> 0.05), however with a difference between the third millimeter and the others (P <0.05). The three-dimensional morphological analyses of volume, surface area and root canal SMI (Structural Model Index) of the root canal showed a similar behavior among the groups. The specimens subjected to complementation to the instrumentation with instruments of tapers 04 and 02 showed no statistically significant difference after preparation (P> 0.05), with significant difference between the original and prepared canals (P <0.05). When comparing the sets of groups, no analogue group presented a statistically significant difference (P> 0.05). Transport was analyzed by thirds (cervical, middle and apical) and throughout the canal there, without statistically difference (P> 0.05) among the thirds or between groups with complementation with taper 04 (MTwo) and taper 02 (K3) instruments.

<p>Timber drying is one of the most important processes whenmanufacturing sawn timber products. The drying processinfluences deformations, surface checking, discoloration andhence, the product quality and the manufacturing costs.Research in this field is of great importance for the woodindustry since the industrial drying process always needs to beimproved as market demands increases and new wood products aredeveloped.</p><p>The aim of the present thesis was to investigate themoisture transport behaviour in wood based on measurementsduring drying from fresh condition down to end use moisturecontent. The behaviour near the surface interface has beenspecifically investigated since it is of great importance forthe theoretical description of the drying process. Furthermore,studies based on measurements in the wood surface layer duringdrying are not easy to find in the literature. The reason forthat is probably that it is very difficult to make accuratemoisture measurements with high spatial or temporal resolutionwithout disturbing the drying process.</p><p>Measurements of moisture content profiles in Scots pineheartwood and sapwood during drying have been performed byusing three different methods. The first was a destructivemethod where the wood samples are sliced with a knife intoseveral smaller pieces. The moisture content in each piece wasdetermined with the dry weight method. The second method usedis non-destructive and it utilises a medical CT-scanner thathas been adapted for drying experiments. The samples are driedin-situ the scanner through the whole experiment. TheCT-scanner measures density and the moisture content arecalculated according to existing methods developed by otherscientists. The third method was also non-destructive and itutilises a Magnetic Resonance Imaging, MRI, technique. Withthis technique the amount of water in the wood sample ismeasured directly even though it has to be calibrated tomoisture content.</p><p>The surface emission factor, S, or surface resistance, 1/S,has been studied by performing sorption experiments with MDF ina narrow moisture content range. The experiment was evaluatedusing a simple diffusion model that includes a surface emissionfactor S. The experimental result was compared with resultscalculated using well established boundary layer theories.</p><p>Measurements of moisture content profiles in the wood bulkshowed an expected Fickian behaviour at moisture contents belowthe fibre saturation point. Above the fibre saturation pointalmost flat moisture profiles were observed. This behaviour wasnot expected and it is not possible to simulate this behaviourwith the existing drying models since they usually assume thatthere is a gradient in the moisture profile over the wholemoisture content range. From the moisture profiles thediffusion coefficients were determined over a moisture contentranging from 8 to 30%. The values for heartwood and sapwood areapproximately equal in radial and tangential direction tograin. Furthermore, the diffusion values in longitudinaldirection are much higher as expected.</p><p>The sorption experiments with MDF gave a greater surfaceresistance compared with the calculation that was based onboundary layer theory. The ratio was three or higher. Thisimplied that there was a greater resistance in the surfacelayer. In addition, this was not well described in theliterature even though a few recent published studiesexist.</p><p>High resolution measurements in the surface layer of woodshowed behaviour similar to that observed in the bulk wood. Theresults showed the very early development of a dry zone closeto the surface interface. In that zone or shell the moisturecontent was below the FSP even though the bulk moisture contentwas far above the FSP. At the end of the experiments themoisture content in the surface layer (0–300 µm)nearly reached the equilibrium moisture content even though thebulk moisture content still was much higher.</p><p><b>Keywords:</b>Computer tomography, Diffusion, Magneticresonance, Moisture measurements, Moisture profiles, Surfaceemission, Wood drying</p>

No description available.

O objetivo do trabalho foi avaliar as alterações morfológicas bi, tridimensionais, e o transporte em canais mesiais de molares inferiores com curvatura acentuada. Selecionou-se molares inferiores com dois canais e forames independentes, livres de nódulos pulpares, reabsorção interna, tratamento endodôntico prévio, fratura radicular e dentro do padrão de raio e ângulo de curvatura, avaliados pelos exames radiográficos, tomográficos cone bean e microtomográficos. Partiu-se de 393 dentes para selecionar 15 dentro deste padrão morfológico. Esses dentes foram submetidos à microtomografia antes da instrumentação, após o preparo com instrumento Reciproc® R25 e após o preparo por cada lima dos sistemas de complementação (Mtwo e K3). Os dados morfométricos foram analisados pelo programa CTAn e as análises estatísticas foram realizadas utilizando o programa SPSS onde observou-se os seguintes resultados: a análise morfométrica bidimensional mostrou que a área e o perímetro apresentaram aumento gradual a cada milímetro avaliado, partindo do primeiro milímetro apical; houve também aumento gradual de área e de perímetro a cada troca de instrumento de acordo com o que se realizou o preparo biomecânico dentro dos conjuntos de grupos; houve diferença estatisticamente significante de área e de perímetro dos canais radiculares apenas após o preparo com os instrumentos #40 taper 04 e taper 02 (P<0,05). Em relação à distância do ápice, houve diferença estatística de área entre todos os milímetros avaliados (P<0,05). Em relação ao perímetro, não houve diferença entre os milímetros 1 e 2; e, 4 e 5 (P>0,05), entretanto com diferença entre o terceiro milímetro e os demais (P<0,05). As análises morfológicas tridimensionais de volume, área de superfície e SMI (Índice de Modelo Estrutural) do canal radicular, tiveram comportamento semelhante entre os grupos. Os espécimes submetidos à complementação, com instrumentos taper 04 e taper 02, não apresentaram diferença estatística após os preparos (P>0,05), com diferença entre os canais preparados com a R25 e os canais originais (P<0,05). Quando comparados os conjuntos de grupos, nenhum grupo análogo apresentou diferença estatística (P>0,05). Foi analisado o transporte por terços (cervical, médio e apical) e por todo o canal, não sendo detectada diferença estatisticamente significante (P>0,05) entre os terços, nem do canal todo entre a complementação pelos instrumentos taper 04 (Mtwo) e taper 02 (K3). / The purpose of this study was to evaluate the two- and three-dimensional morphological changes, and the transportation that occurs in the mesial canals of mandibular molars with severe curvature. Molars were selected with two independent canals and foramina, no pulpal nodules, internal resorptions, previous endodontic treatment or root fracture and within the standard radius and angle of curvature evaluated by radiographs, cone-beam tomography and microtomography. From the 393 teeth initially selected, 15 fulfilled the selected parameters. The teeth were subjected to microtomography before instrumentation, after instrumentation with Reciproc® R25 and after preparation with each file of the complementary systems (MTwo and K3). The morphometric data were analyzed by CTAn software and the statistical analysis was performed using the SPSS software where the following results were observed. The two-dimensional morphometric analysis showed that the area and the perimeter presented a gradual increase for every evaluated millimeter, starting from the first apical millimeter. There was also a gradual increase in area and perimeter with each change of instrument according to the biomechanical within the sets of groups. There was a statistically significant difference in area and perimeter of root canals after the preparation with the instruments #40 taper 04 and taper 02 (P <0.05). Regarding the distance from the apex area, there was statistically difference among all evaluated millimeters (P <0.05). Regarding the perimeter, there was no difference between 1 and 2 mm, and 4 or 5 (P> 0.05), however with a difference between the third millimeter and the others (P <0.05). The three-dimensional morphological analyses of volume, surface area and root canal SMI (Structural Model Index) of the root canal showed a similar behavior among the groups. The specimens subjected to complementation to the instrumentation with instruments of tapers 04 and 02 showed no statistically significant difference after preparation (P> 0.05), with significant difference between the original and prepared canals (P <0.05). When comparing the sets of groups, no analogue group presented a statistically significant difference (P> 0.05). Transport was analyzed by thirds (cervical, middle and apical) and throughout the canal there, without statistically difference (P> 0.05) among the thirds or between groups with complementation with taper 04 (MTwo) and taper 02 (K3) instruments.