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<p>Human vision has an incredible ability to translate light reaching the retinae into a coherent, three-dimensional representation of the outside world in a fraction of a second. Much research has been devoted to understanding how local orientation information is integrated to form global contours and shapes -– a crucial step in visual processing. This dissertation describes experiments examining how contour and shape perception are affected in healthy aging.</p> <p>Chapter 2 examined contour grouping at low contrast and in the absence of distracters. Unlike younger subjects, older subjects did not benefit from co-alignment of local orientations with the contour’s outline, suggesting that grouping by orientation co-alignment is impaired in older age in low contrast. Chapters 3 and 4 examined the effects of aging on the ability to detect and discriminate high-contrast contours embedded in a dense field of distracters, as real life situations often require detecting objects among clutter, such as a snake hiding among tall grass. Results showed that older adults require significantly more time to discriminate contours in clutter, especially for less salient contours. Moreover, increasing the relative density of background clutter had a greater detrimental effect on older, compared to younger, subjects. However, aging did not seem to affect the ability to group contours across a range of spatial distances, or the sensitivity of contour integration to orientation misalignment. Lastly, Chapter 5 examined the influence of local orientation information on the perception of a contour's shape. Results revealed that older and younger subjects perceived the shape of a sampled contour in the same way, even when the contour's orientation and position information were in conflict. These findings indicated that the integration of orientation and position information in shape perception does not change with age.</p> / Doctor of Philosophy (PhD)

Historical topographic maps are valuable resources for studying past landscapes, but they are unsuitable for geospatial analysis. Cartographic map elements must be extracted and digitized for use in GIS. This can be accomplished by sophisticated image processing and pattern recognition techniques, and more recently, artificial intelligence. While these methods are generally effective, they require high levels of technical expertise. This study presents a straightforward method to digitally extract historical topographic map elements from within popular GIS software, using new and rapidly evolving toolsets. A convolutional neural network deep learning model was used to extract elevation contour lines from a 1940 United States Geological Survey (USGS) quadrangle in Sevier County, TN, ultimately producing a Digital Elevation Model (DEM). The topographically derived DEM (TOPO-DEM) is compared to a modern LiDAR-derived DEM to analyze its quality and utility. GIS-capable historians, archaeologists, geographers, and others can use this method in research and land management.

Security cameras installed in public spaces or in private organizations continuously record video data with the aim of detecting and preventing crime. For that reason, video content analysis applications, either for real time (i.e. analytic) or post-event (i.e. forensic) analysis, have gained high interest in recent years. In this thesis, the primary focus is on two key aspects of video analysis, reliable moving object segmentation and carried object detection & identification. A novel moving object segmentation scheme by background subtraction is presented in this thesis. The scheme relies on background modelling which is based on multi-directional gradient and phase congruency. As a post processing step, the detected foreground contours are refined by classifying the edge segments as either belonging to the foreground or background. Further contour completion technique by anisotropic diffusion is first introduced in this area. The proposed method targets cast shadow removal, gradual illumination change invariance, and closed contour extraction. A state of the art carried object detection method is employed as a benchmark algorithm. This method includes silhouette analysis by comparing human temporal templates with unencumbered human models. The implementation aspects of the algorithm are improved by automatically estimating the viewing direction of the pedestrian and are extended by a carried luggage identification module. As the temporal template is a frequency template and the information that it provides is not sufficient, a colour temporal template is introduced. The standard steps followed by the state of the art algorithm are approached from a different extended (by colour information) perspective, resulting in more accurate carried object segmentation. The experiments conducted in this research show that the proposed closed foreground segmentation technique attains all the aforementioned goals. The incremental improvements applied to the state of the art carried object detection algorithm revealed the full potential of the scheme. The experiments demonstrate the ability of the proposed carried object detection algorithm to supersede the state of the art method.

La segmentation d'image par modèles déformables est une méthode permettant de localiser les frontières d'un objet. Dans le cas d'images difficiles à segmenter en raison de la présence de bruit ou d'un manque d'information, l'introduction de connaissance a priori dans le modèle déformable améliore la segmentation. Ces cas difficiles sont fréquents dans l'imagerie du vivant, où les applications peuvent concerner le traitement d'une grande quantité de donnée. Il est alors nécessaire d'utiliser une méthode de traitement robuste et rapide. Cette problématique nous a amené à proposer une régularisation locale du modèle déformable. Pour ce faire, nous reprenons le concept du contour actif en proposant un nouveau schéma de régularisation. Celle-ci est désormais effectuée via un filtrage RII des déplacements à chaque itération. Le filtre est basé sur un noyau de spline lissante dont le but, à l'origine, était d'approcher un ensemble de points par une fonction continue plutôt que d'interpoler exactement ces points. Nous mettons en avant, dans cette méthode de régularisation, la concision du paramètre de régularisation : il s'agit d'une valeur ?, réelle et positive, qui influe sur la fréquence de coupure du filtre passe-bas. Une relation analytique existant entre ?, la fréquence de coupure et la fréquence d'échantillonnage, il est possible de donner un sens métrique à la fréquence de coupure. De plus, nous pouvons affecter une valeur ? différente en chaque point du contour par une variation des coefficients du filtre et ainsi permettre une régularisation locale du contour actif. La généralisation de cette nouvelle méthode de régularisation pour des modèles déformables surfaciques est proposée. La difficulté principale concerne la connectivité du maillage, contrainte à une valence 4 partout par le filtrage bidimensionnel. Des résultats de segmentation sont donnés pour de tels maillages ainsi que pour des maillages sphériques où un traitement particulier des pôles est mis en oeuvre.

Prostate segmentation is a required step in determining the volume of a prostate, which is very important in the diagnosis and the treatment of prostate cancer. In the past, radiologists manually segment the two-dimensional cross-sectional ultrasound images. Typically, it is necessary for them to outline at least a hundred of cross-sectional images in order to get an accurate estimate of the prostate's volume. This approach is very time-consuming. To be more efficient in accomplishing this task, an automated procedure has to be developed. However, because of the quality of the ultrasound image, it is very difficult to develop a computerized method for defining boundary of an object in an ultrasound image. The goal of this thesis is to find an automated segmentation algorithm for detecting the boundary of the prostate in ultrasound images. As the first step in this endeavour, a semi-automatic segmentation method is designed. This method is only semi-automatic because it requires the user to enter four initialization points, which are the data required in defining the initial contour. The discrete dynamic contour (DDC) algorithm is then used to automatically update the contour. The DDC model is made up of a set of connected vertices. When provided with an energy field that describes the features of the ultrasound image, the model automatically adjusts the vertices of the contour to attain a maximum energy. In the proposed algorithm, Mallat's dyadic wavelet transform is used to determine the energy field. Using the dyadic wavelet transform, approximate coefficients and detailed coefficients at different scales can be generated. In particular, the two sets of detailed coefficients represent the gradient of the smoothed ultrasound image. Since the gradient modulus is high at the locations where edge features appear, it is assigned to be the energy field used to drive the DDC model. The ultimate goal of this work is to develop a fully-automatic segmentation algorithm. Since only the initialization stage requires human supervision in the proposed semi-automatic initialization algorithm, the task of developing a fully-automatic segmentation algorithm is reduced to designing a fully-automatic initialization process. Such a process is introduced in this thesis. In this work, the contours defined by the semi-automatic and the fully-automatic segmentation algorithm are compared with the boundary outlined by an expert observer. Tested using 8 sample images, the mean absolute difference between the semi-automatically defined and the manually outlined boundary is less than 2. 5 pixels, and that between the fully-automatically defined and the manually outlined boundary is less than 4 pixels. Automated segmentation tools that achieve this level of accuracy would be very useful in assisting radiologists to accomplish the task of segmenting prostate boundary much more efficiently.

The electro-optic technique of measuring the cardiovascular pulse wave known as photoplethysmography (PPG) is clinically utilised for noninvasive characterisation of physiological components by dynamic monitoring of tissue optical absorption. There has been a resurgence of interest in this technique in recent years, driven by the demand for a low cost, compact, simple and portable technology for primary care and community-based clinical settings, and the advancement of computer-based pulse wave analysis techniques. PPG signal provides a means of determining cardiovascular properties during the cardiac cycle and changes with ageing and disease. This thesis focuses on the photoplethysmographic signal for cardiovascular assessment. The contour of the PPG pulse wave is influenced by vascular ageing. Contour analysis of the PPG pulse wave provides a rapid means of assessing vascular tone and arterial stiffness. In this thesis, the parameters extracted from the PPG pulse wave are examined in young adults. The results indicate that the contour parameters of the PPG pulse wave could provide a simple and noninvasive means to study the characteristic change relating to arterial stiffness. The pulsatile component of the PPG signal is due to the pumping action of the heart, and thus could reveal the circulation changes of a specific vascular bed. Heart rate variability (HRV) represents one of the most promising quantitative markers of cardiovascular control. Calculation of HRV from the peripheral pulse wave using PPG, called pulse rate variability (PRV), is investigated. The current work has confirmed that the PPG signal could provide basic information about heart rate (HR) and its variability, and highly suggests a good alternative to understanding dynamics pertaining to the autonomic nervous system (ANS) without the use of an electrocardiogram (ECG) device. Hence, PPG measurement has the potential to be readily accepted in ambulatory cardiac monitoring due to its simplicity and comfort. Noncontact PPG (NPPG) is introduced to overcome the current limitations of contact PPG. As a contactless device, NPPG is especially attractive for physiological monitoring in ambulatory units, NICUs, or trauma centres, where attaching electrodes is either inconvenient or unfeasible. In this research, a prototype for noncontact reflection PPG (NRPPG) with a vertical cavity surface emitting laser (VCSEL) as a light source and a high-speed PiN photodiode as a photodetector is developed. The results from physiological experiments suggest that NRPPG is reliable to extract clinically useful information about cardiac condition and function. In summary, recent evidence demonstrates that PPG as a simple noninvasive measurement offers a fruitful avenue for noninvasive cardiovascular monitoring. Key words: Photoplethysmography (PPG), Cardiovascular assessment, Pulse wave contour analysis, Arterial stiffness, Heart rate (HR), Heart rate variability (HRV), Pulse rate variability (PRV), Autonomic nervous system (ANS), Electrocardiogram (ECG).

Este trabalho discute a determinação de padrões respiratórios em sequências temporais de imagens obtidas por Ressonância Magnética (RM) e o seu uso no registro temporal de imagens coronais e sagitais. O registro é feito sem o uso de qualquer informação de sincronismo e qualquer gás especial para reforçar o contraste. As sequências temporais de imagens são adquiridas em respiração livre. O movimento real do pulmão nunca foi diretamente visto, pois é totalmente dependente dos músculos que o rodeiam. A visualização do pulmão em movimento é um tema atual de pesquisa na medicina. O movimento do pulmão não possui intervalos regulares e é suscetível a variações na respiração. Comparado à Tomografia Computadorizada (TC), a RM necessita de um maior tempo de aquisição e é preferível porque não envolve radiação. Como as sequências de imagens coronais e sagitais são ortogonais entre si, a sua intersecção corresponde a um segmento de reta no espaço tridimensional. O registro se baseia na análise deste segmento interseccional. A variação deste segmento de interseção no tempo pode ser enfileirada, definindo uma imagem espaço-temporal em duas dimensões (2DST). Supõe-se que o movimento diafragmático é o movimento principal de todas as estruturas do pulmão se movem quase que totalmente sincronicamente. A sincronização deste movimento é feita através de um padrão chamado função respiração. Este padrão é obtido através do processamento de uma imagem 2DST. Um algoritmo da transformada de Hough intervalar procura movimentos sincronizados na função respiração. O algoritmo de contornos ativos ajusta pequenas discrepâncias originadas por movimentos assíncronos nos padrões respiratórios . A saída é um conjunto de padrões respiratórios. Finalmente, a composição de imagens coronal e sagital que estão na mesma fase respiratória é realizada através da comparação de padrões respiratórios provenientes das superfícies de contorno superior e diafragmática. Quando disponíveis, os padrões respiratórios associados às estruturas internas do pulmão também são usados. Vários resultados e conclusões são apresentados. / This work addresses the determination of the breathing patterns in time sequence of images obtained from Magnetic Resonance (MR) and their use in the temporal registration of coronal and sagital images. The registration is done without the use of any triggering information and any special gas to enhance the contrast. The temporal sequences of images are acquired in free breathing. The real movement of the lung has never been seen directly, as it is totally dependent on its surrounding muscles and collapses without them. The visualization of the lung in motion is an actual topic of research in medicine. The lung movement is not periodic and it is susceptible to variations in the degree of respiration. Compared to Computerized Tomography (CT), MR imaging involves longer acquisition times and it is preferable because it does not involve radiation. As coronal and sagittal sequences of images are orthogonal to each other, their intersection corresponds to a segment in the three dimensional space. The registration is based on the analysis of this intersection segment. A time sequence of this intersection segment can be stacked, defining a two-dimension spatio-temporal (2DST) image. It is assumed that the diaphragmatic movement is the principal movement and all the lung structures move almost synchronously. The synchronization of this motion is performed through a pattern named respiratory function. This pattern is obtained by processing a 2DST image. An interval Hough transform algorithm searches for synchronized movements with the respiratory function. A greedy searches for synchronized movements with the respiratory function. A greedy active contour algorithm adjusts small discrepancies originated by asynchronous movements in the respiratory patterns. The output is a set of respiratory patterns. Finally, the composition of coronal and sagittal images that are in the same breathing phase is realized by comparing of respiratory patterns originated from diaphragmatic and upper boundary surfaces. When available, the respire tory patterns associated to lung internal structures are also used. Several results and conclusions are shown.