Background: Injecting drug users (IDUs) represent considerable group of patients infected with hepatitis C virus (HCV). HCV treatment is an effective tool for reduction of HCV transmissions among IDUs. Nevertheless treatment rate among IDUs is rather insufficient. Treatment uptake, provision and adherence as well as its efficacy in IDUs are determined by number of specific factors. Aims: Mapping an extent of the provision of HCV treatment to IDUs in the Czech Republic, rules and practices for the admission of IDUs into HCV treatment and its provision, describing relevant factors related to drug use. Material and methods: From January to March 2011, a questionnaire survey among centres for treatment of viral hepatitis in the Czech Republic was conducted. 76 identified centres were addressed, of which 45 (59%) responded, and 40 (53%) filled in an online questionnaire. Results: Estimated number of centres treated HCV with combination of pegylated interferon α and ribavirin in the Czech Republic in 2010 was 61, 39 of them treated IDUs. Estimated 780 persons were treated, of whom 370 were (mostly ex-) IDUs. Reported treatment uptake in IDUs was 60% on average (range 0-90%). Treatment is completed by 80% of IDUs on average (0-100%) according to clinicians. Most clinicians reported no difference in the treatment...

Basis: In the Czech Republic, an estimated 46.8 thousand problem drug users and the prevalence of infectious diseases (mainly viral hepatitis C) among problem users are high. This may be related not only to the actual use of drugs but also to their risky sexual behavior through which they can transmit infectious diseases as well. Objective: The main goal of this thesis is to describe the occurrence of risk sexual behavior in problem drug addicts using low-threshold addictology services in České Budějovice. Methods: The results of this thesis were processed on the basis of answers from an anonymous questionnaire from 50 clients of the contact center in České Budějovice, with a total of 12% of clients' contact centers. They were addressing respondents who came to take advantage of the exchange program or contact room. A total of 19 women and 31 men participated in the survey, the average age of respondents was 32 years. The research results were identified and processed in graphs through descriptive statistics. The data was evaluated in Microsoft Excel and then in Microsoft Word. Results: The results show a certain connection between problematic use of addictive substances and risky sexual behavior. Respondents who have ever been sexually at risk have mostly become drug addicts (88% of respondents),...

Basis: Statistical data of the Police of the Czech Republic show that secondary drug crime is widespread among abusers of addictive substances in the entire Czech Republic. The crime is mainly due to the need for financial resources for buying the addictive substance. As a result, every addictive substance abuser is perceived as a potential perpetrator of a crime. Aim: The aim of this diploma thesis was to find out the incidence of secondary drug criminality in the clients of the contact center DRUG - OUT Klub, z. s. in Ústí nad Labem, and to study the effect of selected influential demographic factors (gender, age, type of addictive substance, duration of addictive substance abuse). Methods and Research Sample: The research was conducted in the drug addiction treatment center DRUG - OUT Klub, s. z. in Ústí nad Labem using a questionnaire. The research respondents were problem abusers of opioids and stimulants. The research sample was selected with help of the institution. Every client of the contact center, who was a problem opioid or stimulant abuser, was over 18 years old, and agreed to be part of the research could participate. The research sample consisted of 362 problem abusers of opioids and stimulants. Among those were 201 men (60 opioid abusers, 141 stimulant abusers) and 161 women (55...

The purpose of this study has been to examine what attitudes young adults have on drugs by problematizing what influence education might have on potential drug use. Furthermore, the study wants to scrutinize how primary schools use Alcohol, Narcotics. Doping, Tobacco teaching (ANDT).   The method used for acquiring empirical data constituted of two focus groups with a total of ten young adults and a survey with twelve primary school principals. The conversations from the focus groups were recorded, transcribed and analyzed thematically which resulted in four different themes.   The results demonstrate that the respondents have shaped their attitudes on drugs through their parents during their upbringing. Furthermore, the results display how attitudes on drugs might be influenced by peer pressure. However, teaching in school did not show any correlation to the respondents’ attitudes.   The conclusion of the study is that knowledge about drugs in general might result in a better understanding about the consequences, for instance how drug use damages the body and might create an addiction. The study shows that the attitudes among young adults are shaped under influence of several factors and arenas, but that further research on the topic is still needed for the public health.

This thesis deals with the reintegration of persons recovering from drug addiction and their return to the labour market. The reintegration model is chosen by social company, Café Therapy, one of the first social enterprises to focus specifically on the re-employment of individuals. The main goal of this work is to analyse how successful the company has been, in terms of social effectiveness and self-sufficiency and whether or not the funds invested return by way of the tax system. The objective is to evaluate the effectiveness of this particular social business. It also outlines the recommendations arising from the results of the findings. This work is mainly based on the theory of social exclusion, which can be defined as exclusion from social and economic way of life of society. Therefore, reintegration into society and the labour market is regarded as the main prerequisite to recovery. Concluding, attention is paid to active substance users and opportunities for clients to not only help themselves, but society as a whole.

The diploma thesis focuses on the awareness of 2nd grade pupils of the selected primary school about the causes and consequences of the use of selected addictive substances. The work is divided into theoretical and practical part. The theoretical part describes the drug scene in the Czech Republic and the drug policy of the Czech Republic, the concepts of drug addiction, physical and mental addiction. The diploma thesis is focused on legal drugs - alcohol, tobacco, caffeine and illegal drugs - specifically on cannabis drugs. The next part of the work deals with addictive problems in children and adolescents and current trends in the use of addictive substances in young people in the Czech Republic according to several studies. At the end of the theoretical part, risk and protective factors influencing the emergence of addiction and risks and the consequences of selected addictive substances are described. The practical part maps the awareness of 2nd grade students of the selected elementary school about the causes and consequences of the use of selected addictive substances before and immediately after my performance in the subject of health education, including the 2nd month interval from the topic. The aim of the practical part was also to point out the low awareness of respondents about the...

The thesis deals with the NQR spectroscopy, which is one of the modern non-destructive measurement and diagnostic methods for the characterization of various materials. It is using a quadrupole moment - a property of atomic nuclei of certain isotopes. A method of nuclear quadrupole resonance (NQR) is in principle very similar to nuclear magnetic resonance (NMR). Thesis in the theoretical part analyse the principles of NMR and NQR, describes the possible use of this method to detect for example explosives, drugs, and other chemicals. In the following chapters are analysed the key parameters of NQR spectrometer and the principle of the chosen measurement method. The practical part deals with the individual components of NQR spectrometer, the design of possible improvements and programming of the measuring sequence. In the final chapter are processed the measurements of the submitted samples.

The result of this diploma thesis is based on the collected data, to evaluate the success of the detection of narcotic and psychotropic substances by a policeman, with subsequent measuring and professional expression. The thesis is divided into three parts. In the theoretical part, this is mainly an evaluation of existing information dealing with drug issues related to road accidents. In the analytical part, the thesis deals with real methods and equipment with OPL detection. The practical part contains data obtained from qualitative research, through interviews, which are compared and evaluated with a quantitative survey of the questionnaire survey, which can help to improve expert judgment and improve transport safety.

Background: At the point, when injecting still seems to be the most common use among problem drug users and there has been no change in the long term, despite the long tradition of harm reduction services in the Czech Republic, it is important to examine the context of this issue and try to understand it more closely, and therefore understanding the phenomenon of needle fixation. Aims: The paper seeks to address whether the risky behaviour level of the needle-fixated drug users differs from those who are not needle-fixated. The second aim is to examine a possible connection between the injecting users psychopathological characteristics and the phenomenon of needle fixation. The third intention of the work is to find out whether and pošibly how the level of risky behaviour differs among needle-fixated drug users in the context of their psychopathological characteristics. Methods: The chosen method of data collection was a battery of questionnaires: IN-COME questionnaire, BBV-TRAQ, SCL-90 and NEFPRO. The battery of the questionnaire was administered with the participation of the researcher. In addition to descriptive statistical methods, the Mann-Whitney test (4 tests), the Chi-square test (11 tests) and the Spearman correlation coefficient were chosen as methods for testing based on research...

The aim of this paper is to explain the policy process of regional social service development strategies in the area of services for drug users. The process is explained on examination of two cases of very diverse regional strategies representing good and bad practice. Social construction of target populations is used as a theoretical framework and the research aims to verify and develop its theoretical assumptions. Subjective perceptions of key actors are deconstructed through public document analysis and in- depth interviews. Service providers are perceived as a trustworthy and competent policy actor and as such they play an important role in the development of medium-term strategy. The prevailing positive construction of drug users by providers and the strong position of service providers contribute to broad distribution of services for drug users in both examined regions. The main difference between the cases is explained by different perception of drug users by the public, different continuity of planning processes, and variance in the dynamic relationship between public opinion and key public policy makers.