Abstrakt Fysisk aktivitet på recept (FaR), är en metod som används för att förebygga och behandla folksjukdomar. Syftet med FaR är att få individer att bli mer fysiskt aktiva [FA] och därigenom påverka sjukdomsbesvären i en positiv riktning. Till denna förändring krävs motivation och någonting som skapar en vilja att utföra FA. Syftet med denna studie har därför varit att undersöka om ett FaR- recept kan motivera till ökad FA hos FaR-klienter. Den metod som användes var semistrukturerade intervjuer med öppna frågor. Sex respondenter deltog i studien. Kravet var att personerna skulle ha FaR-recept. Resultatet pekar på att det upplevda stödet från såväl sjukvården, FaR- ledaren samt den sociala delen i form av familj, vänner och bekanta spelar stor roll för skapandet och upprätthållandet av motivation till FA hos FaR- klienten. Slutsatsen är att genom förmedlad kunskap och stöd från sjukvården och FaR- ledaren skapas en meningsfullhet, förståelse och hanterbarhet hos klienten. Detta kan leda till att öka motivationen till FA hos FaR-klienten. / Abstract Physical activity on prescription, (PaP), is a method used to prevent and treat common diseases. The aim of PaP is to get individuals to become more physically active [PA] and through that influence the disorders in a positive direction through a more active lifestyle. This change requires motivation and something that creates a desire to perform the PA. The purpose of this study was therefore to investigate whether a prescriptions may warrant increased PA in the clients. The methodology used in this study was semi-structured interviews with open questions. Six respondents participated. The requirement was that the people would have a PaP- prescription. The results indicate that the perceived support from both the healthcare, PaP- leader and social support plays a major role in the creation and maintenance of motivation to the PA in the PaP- client. The conclusion is that the mediated knowledge and support from health care and PaP leader created a meaningfulness, understanding and manageability of the client. This can lead to increased motivation to PA in PaP client.

Made available in DSpace on 2014-12-17T13:57:08Z (GMT). No. of bitstreams: 1 KarlaSCCA_DISSERT_Capa_ate_pag49.pdf: 4603204 bytes, checksum: b52448152d451ce76ca78743e0d28711 (MD5) Previous issue date: 2012-04-04 / The employment of flexibility in the design of fa?ades makes them adaptable to adverse weather conditions, resulting in both minimization of environmental discomfort and improvement of energy efficiency. The present study highlights the potential of flexible fa?ades as a resource to reduce rigidity and form repetition, which are usually employed in condominiums of standardized houses; as such, the work presented herein contributes to field of study of architectural projects strategies for adapting and integrating buildings within the local climate context. Two fa?ade options were designed using as reference the bionics and the kinetics, as well as their applications to architectural constructions. This resulted in two lightweight and dynamic structures, which cater to constraints of comfort through combinations of movements, which control the impact of solar radiation and of cooling in the environment. The efficacy and technical functionality of the fa?ades were tested with comfort analysis and graphic computation software, as well as with physical models. Thus, the current research contributes to the improvement of architectural solutions aimed at using passive energy strategies in order to offer both better quality for the users and for the sustainability of the planet / O emprego da flexibilidade no desenho das fachadas, tornando-as adapt?veis a situa??es clim?ticas adversas, conduz a minimiza??o do desconforto ambiental e a efici?ncia energ?tica. Desse modo, esta pesquisa evidencia o potencial de fachadas flex?veis como recurso para diminuir a rigidez e a repeti??o da forma, comumente empregada em condom?nios de casas padronizadas, contribuindo para o aprofundamento no estudo de estrat?gias de projeto que auxiliam na adapta??o e integra??o do edif?cio com o clima e contexto locais. Para tanto, duas op??es de fachadas foram projetadas utilizando como refer?ncia a bi?nica e a cin?tica e suas aplica??es em constru??es arquitet?nicas. Como resultados foram obtidos duas estruturas leves e din?micas que atendem aos condicionantes de conforto por meio de combina??es de movimentos que controlam a radia??o solar e o arrefecimento no ambiente. A efic?cia e funcionalidade t?cnica das fachadas foram testadas por meio de softwares de an?lises de conforto e computa??o gr?fica e simula??es com maquete f?sica. Assim, a pesquisa contribui para o aperfei?oamento de solu??es projetuais objetivando o uso de estrat?gias de energia passiva na arquitetura com o intuito de oferecer melhor qualidade para o usu?rio e para a sustentabilidade do planeta

A Wireless Sensor Network (WSN) is a group of spatially dispersed sensors that monitor the physical conditions of the environment and collect data at a central location. Sensor deployment is one of the main design aspects of WSNs as this a ffects network coverage. In general, WSN deployment methods fall into two categories: planned deployment and random deployment. This thesis considers planned sensor deployment of a Mobile Wireless Sensor Network (MWSN), which is defined as selectively deciding the locations of the mobile sensors under the given constraints to optimize the coverage of the network. Metaheuristic algorithms are powerful tools for the modeling and optimization of problems. The Krill Herd Algorithm (KHA) is a new nature-inspired metaheuristic algorithm which can be used to solve the sensor deployment problem. A Multi-Agent System (MAS) is a system that contains multiple interacting agents. These agents are autonomous entities that interact with their environment and direct their activity towards achieving speci c goals. Agents can also learn or use their knowledge to accomplish a mission. Multi-agent systems can solve problems that are very difficult or even impossible for monolithic systems to solve. In this work, a modification of KHA is proposed which incorporates MAS to obtain a Multi-Agent Krill Herd Algorithm (MA-KHA). To test the performance of the proposed method, five benchmark global optimization problems are used. Numerical results are presented which show that MA-KHA performs better than the KHA by finding better solutions. The proposed MA-KHA is also employed to solve the sensor deployment problem. Simulation results are presented which indicate that the agent-agent interactions in MA-KHA improves the WSN coverage in comparison with Particle Swarm Optimization (PSO), the Firefly Algorithm (FA), and the KHA. / Graduate

Trois essais cliniques ARISTOTLE, RE-LY et ROCKET-AF, sont réalisés sur les quatre nouveaux anticoagulants oraux qui sont l’Apixaban, le Dabigatran 110mg, Dabigatran 150mg et le Rivaroxaban, afin d’améliorer la prise en charge de la fibrillation auriculaire (FA). Ils ne permettent pas de déterminer la meilleure option thérapeutique. L’objectif de cette thèse est de développer une approche d’aide multicritère à la décision pour la problématique du choix thérapeutique appliquée au cas de la FA afin d’évaluer ces quatre options thérapeutiques médicamenteuses. La méthodologie d’aide multicritère développée, PROMETHEE-GAIA appliquée à la FA permet de comparer ces quatre nouveaux anticoagulants (l’Apixaban, le Dabigatran 110mg, Dabigatran 150mg et le Rivaroxaban) en se basant sur les cinq critères essentiels élaborés selon un processus de concertation cadrée, qui sont l’efficacité, la sécurité, la fonction rénale, l’observance et le prix. Les résultats de l’évaluation de ces quatre nouveaux anticoagulants est un classement de ces options thérapeutiques par leur ordre de performance dans la prise en charge des patients de la FA selon ces cinq critères en considération.

This thesis deals with the production and characterization of cheese analogues, ie products in which some of the dairy components are mutually or completely replaced by a non-dairy component. Model samples of fresh cheese and analogues of fresh cheese (standard) with the addition of linseed and rapeseed oil were produced by a standard technological procedure in MENDELU Brno. The content of bound and free fatty acids, volatile (aroma) substances and sensory quality was monitored in the samples. The main focus was to evaluate the effect of added vegetable oil on the monitored parameters. The fats from the sample were extracted with a mixture of diethyl ether and petroleum ether. Fatty acids were converted to methyl esters by boron trifluoride-catalyzed acid esterification and subsequently identified by GC-FID. The analysis found a higher content of fatty acids in cheese analogues in comparison with the control sample, also the content of unsaturated fatty acids increased. The HS-SPME-GC-MS method was used for the identification and semi-quantification of volatile substances (aromatic substances). 56 volatile compounds were identified in the samples; The percentage of individual chemical groups differed significantly, the highest content was found in the control sample. Sensory evaluation was performed using a scale and a serial test. In all of monitored indicators (apparence, color, consistency, smell and taste) the control sample was evaluated as best. As for the analogues the taste and smell of used oils were detected, which was unpleasant for the evaluators. The obtained results show that the addition of vegetable oils increases the nutritional value of cheeses (higher content of unsaturated fatty acids), but reduces their sensory quality and overall consumer acceptability.

Purpose: One relevant aspect for anastomotic leakage in colorectal surgery is blood perfusion of both ends of the anastomosis. The clinical evaluation of this issue is limited, but new methods like fluorescence angiography with indocyanine green or non-invasive and contactless hyperspectral imaging have evolved as objective parameters for perfusion evaluation. Methods: In this prospective, non-randomized, open-label and two-arm study, fluorescence angiography and hyperspectral imaging were compared in 32 consecutive patients with each other and with the clinical assessment by the surgeon. After preparation of the bowel and determination of the surgical resection line, the tissue was evaluated with hyperspectral imaging for 5 minutes before and after cutting the marginal artery and assessed by 6 hyperspectral pictures followed by fluorescence angiography with indocyanine green. Results: In 30 of 32 patients the image data could be evaluated and compared. Both methods provided a comparable borderline between well perfused and poorly perfused tissue (p = 0.704). In 15 cases, the surgical resection line was shifted to the central position due to the imaging. The border zone was sharper in fluorescence angiography and was best assessed 31sec after injection. With hyperspectral imaging, the border zone was visualized wider and with more differences between proximal and distal border. Conclusion: Hyperspectral imaging and fluorencence angiography provide similar results in determining the perfusion border. Both methods allow a good and safe visualization of the blood perfusion at the central resection margin to create a well-perfused anastomosis.:Abbildungsverzeichnis II Abkürzungsverzeichnis III 1. Einleitung 1 1.1 Anastomoseninsuffizienz 1 1.2 Hyperspektralbildgebung 2 Methodik und technische Daten 2 1.3 Fluoreszenzangiographie mit Indocyaningrün 4 Methodik und technische Daten 4 Anwendungsgebiet 6 1.4 Chirurgische Technik 6 1.5 Studiendesign und intraoperative Bildgebung 7 1.6 Bisherige Ergebnisse 10 2. Publikation 12 3. Zusammenfassung der Arbeit 21 4. Literaturverzeichnis IV 5. Darstellung des eigenen Beitrags VIII 6. Erklärung über die eigenständige Abfassung der Arbeit IX 7. Danksagung X

This paper deals with the manufacture and characterisation of cheese analogues, which are products, where the milk components are totally or partially replaced by non-milk components. Model samples, edam type cheese and the analogue containing hazelnut oil, were manufactured using the standard way at Brno Mendelu. The main parameters chosen to describe the quality of samples were free and bound fatty acids, volatile compounds and sensory quality. The main aim was to judge the influence of added hazelnut oil on mentioned parameters. For the identification and semiquantification of volatile compounds HS-SPME-GC-MS method was used. Fat extraction from sample was made with a mixture of two solvents (diethylether, petrolether), fatty acids were identified and quantified by GC-FID, with their former acid transesterification using methanolic solution of BF3 as a catalyst. For sensory analysis of the appearance, colour, texture, aroma, taste and overall acceptance of the sample descriptive scales and comparison with standard were used, the structure was observed by electron microscopy. The results show that addition of hazelnut oil affects the sensory properties, ripening process (higher amount of volatile compounds, faster lipolysis), nutrition value (higher amount of unsaturated fatty acids), and the stability of the product.

The current investigation replicated and extended previous research on training of behavior professionals to implement functional assessment and analysis procedures. Specifically, the study extended procedures described by Metras to train board certified behavior analysts (BCBAs) to administer two components of the Interview Informed Synthesized Contingency Analyses (IISCA) by: (1) conducting the study in the context of a large residential/training facility for adults with ID, (2) including a participant who served as a behavior analyst for a caseload of individuals who lived and received services at the facility, and (3) adjusting the vignettes and interview scripts to reflect the change in context. This current study shows that, following a brief training sequence, the participant was able to accurately administer the open-ended interview and construct a synthesized test and control condition.

Background: Functional Assessment (FA) in older adults is an important measure of their health status. FA using Activities of Daily Living (ADL) is a strong predictor of health outcomes, especially as we age. With the development of increasingly-connected health, we have a new opportunity for more robust and improved FA. Objective: The objective of this thesis is to collate and discuss published evidence on FA predictors and how the FA predictors can be collected using the paradigm of Connected Health (CH) architectures through an industrial case study in CHAPTER 5: INDUSTRIAL CASE STUDY. Methods: The method is to do two Systematic Literature Reviews (SLRs). The two SLRs were undertaken with Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement (PRISMA) and Parsifal, an online tool for SLR. This thesis catalogs various FA and state-of-the-art Software Engineering Architectural Tactics and Styles (SEATS) used within Connected Health (CH) that focus on ADL. The results of the cataloged information were used in the industrial case study where some of the FA predictors were automated. Articles obtained from the data source during the SLRs were filtered based on the titles, abstracts, full-text provision, English language literature, including age, which must be sixty-five years and above. Another reviewer was also included in this study, while all the defined inclusion and exclusion criteria detailed in this thesis were applied. Information about FA via ADL were extracted from the articles with further extraction on the SEATS used for computer-supported FA during the industrial case study. Data Source: During the SLRs processes, database searched included PubMed, EBSCOhost, Engineering Village, IEEE Xplore Digital Library, and ScienceDirect. The conducted search contains both controlled terms called Medical Subject Headings(MeSH) such as activities of daily living and search strings such as functional assessment, older adults, geriatrics, seniors, elderly care, and aging. Results: From four hundred and ninety-five initial abstracts and titles, nineteen full-text journal articles were included in the final review for the SLR on FA predictors. Six full-text journal articles were obtained from the SLR on CH architectures after reading its 449 titles and abstracts. In the SLR on FA predictors, predictor metrics for FA via ADL were extracted from each of the articles. Gait speed, sleep quality, and movement activities were assessed as ADL predictor metrics for FA in older adults. Other FA predictors published involved self-reported metric scale measurement using Barthel-20 scale and performance-based scale through Timed-UP and Go test. This thesis reviewed each metric for sleep quality and movement activities. In the SLR on CH architectures, quick response of ADL and resource efficiency such as sensors were some of the major tactics related to performance in Software Engineering (SE) quality in CH, while confidentiality and integrity of FA measures related to security in SE quality in CH was another major concern. Conclusion: Having conducted the two SLRs, a wide range of measures were used for FA in older adults, including consideration on the SEATS used for computer-supported FA. Overall, these FA measures and SEATS provide inexpensive and easy-to-implement FA. The diversity of the FA measures and SEATS contributes towards the development of computer-supported FA. However, future work is needed to consider the result of this study as an open-source computer-supported FA tool, and such tool should also be evaluated and verified through direct examination with older adults. / Graduate

This thesis deals with rape and the possibilities of its protection against pests. The most important pests of this crop include rape stem weevil (Ceutorhynchus napi, Gyllenhal 1837), rape beetle (Brassicogethes aeneus Fabricius, 1775 Meligethes aeneus) and brassica pod midge (Dasineura napi, Loew 1850). In the practical part of the dissertation, 26 variants of application sequences of insecticides were evaluated. The first and last variant was taken as a control and therefore not treated with any insecticide. Insecticides were applied on the basis of pest control. In each variant, an insecticide was first applied, which was primarily intended for rape stem weevil (Ceutonhynchus napi, Gyllenhal 1837). The second insecticide was focused on rape beetles (Brassicogethes aeneus Fabricius, 1775, Meligethes aeneus). The third application of the insecticide was determined for the brassica pod midge (Dasineura napi Loew, 1850). The results were evaluated and entered into tables and subsequently statistically processed using Statistica 12. The aim of this work was to evaluate the most effective sequence of three insecticides against the main rapeseed pests. The view was also taken on an anti-resilient strategy in which insecticides having the same active substance should not be applied.