Healing style (zhiyu xi 治愈系 ) media refers to the various products and services labelled with a promise to comfort consumers, and the media category has gradually become viewed as a way to cope with the omnipresent stress and anxiety of modern life. However, there are widespread criticisms of healing style media regarding creating the illusion of comfort for temporary relaxation to avoid facing and addressing the problems that cause discomfort. To counter such biased accusations this thesis examines two types of Chinese healing style media, fiction and anime, to address two main research questions: 1) Whether and how Chinese healing style media respond to the problems people face in real life? 2) How do Chinese healing style media present healing? The textual analyses of the novel Rushan, Gushu and Me reveal that Chinese healing style literature is not creating the illusion of comfort but focuses on the emotional relationship crisis suffered by Chinese people and offers practical solutions with four main steps that integrate the theory and practice of psychotherapy. In the presentation of healing, Chinese healing style writers are inclined to utilize some typical healing elements like character settings that resonate with most people and adequate sensory descriptions. Interpretations combined with screenshots of the anime film The Legend of Hei reinforce the argument that Chinese healing style is not just a comforting fictional world but very concerned with the living space and environmental crises caused by rapid urbanization and emphasizes the importance of reliable intimate relationships in coping with the crises in modern life. In The Legend of Hei, the use of healing elements like natural scenery and colors, resonant characters, delicious foods and positive attitudes all contribute to presenting healing and cater to the psychological needs of the target viewers. Through critically analyzing Chinese healing style fiction and anime, this thesis affirms that they are not escaping but actively presenting the collective crises and providing solutions. This study defends the rationality and effectiveness of Chinese healing style media as one of the many ways to cope with numerous pressures of modern life, thus contributing to a more comprehensive understanding and more appropriate application of Chinese healing style media. / Graduate

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In humans, the epidermis is the main site for the synthesis of Vitamin D3 (cholecalciferol) from 7-dehydrocholesterol. Cholecalciferol undergoes further hydroxylation in the liver and kidney to produce the active form of the circulating hormone 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3). In target cells, 1,25(OH)2D3 interacts with the specific intracellular vitamin D receptor (VDR), a member of the nuclear receptor superfamily. However, epidermal keratinocytes, in addition to being target cells, have enzymes required for autocrine production of 1,25(OH)2D3. They can convert cholecalciferol to 1,25(OH)2D3 via 25-hydroxylase (CYP2R1) and 1α-hydroxylase (CYP27B1). Another enzyme, 24-hydroxylase (CYP24A1), regulates local levels by inactivating 1,25(OH)2D3. While recent studies have shown that absence of VDR or 1,25(OH)2D3 impairs formation of granulation tissue during wound healing in mice, little is known about the autocrine and paracrine regulation of biologically active vitamin D3 by human dermal fibroblasts during cutaneous wound healing. Primary cultures of human keratinocytes and fibroblasts expressed VDR and all the cytochrome enzymes necessary for autocrine production of vitamin D. The relative expression of VDR mRNA was higher in dermal fibroblasts than donor-matched keratinocytes. In contrast, epidermal keratinocytes had a higher mRNA expression of vitamin D3 metabolising enzymes. A scratch wound assay confirmed that 1,25(OH)2D3 stimulated keratinocyte migration, but paradoxically inhibited fibroblast migration as early as 4h, yet neither cholecalciferol nor 25-hydroxyvitamin D3 had any effect. VDR knockdown using small interfering RNA (siRNA) abolished the inhibitory effect of 1,25(OH)2D3 on fibroblast migration, demonstrating the requirement for the VDR in this response. Immunofluorescent staining revealed that 1,25(OH)2D3 increased nuclear VDR protein expression, without a corresponding increase in VDR mRNA transcription only in mechanically wounded dermal fibroblasts, indicating activation of the receptors. Incubation with either 1,25(OH)2D3, cholecalciferol or 25(OH)D3 up-regulated CYP24A1 transcription. This response was most pronounced with 1,25(OH)2D3, suggesting a tightly regulated feedback control on 1,25(OH)2D3 bioavailability within the dermis. In addition, cholecalciferol also increased CYP2R1 and CYP27B1 mRNA expression in scratched dermal fibroblasts, providing evidence for autocrine regulation of 1,25(OH)2D3 by dermal fibroblasts. Expression of α-SMA protein was up-regulated in cultured dermal fibroblasts following scratching, which was down-regulated in the presence of 1,25(OH)2D3. These observations suggest that 1,25(OH)2D3 may restrict differentiation of wounded dermal fibroblasts into pro-fibrotic myofibroblasts. 1,25(OH)2D3 also down-regulated MMP-2 secretion and collagen type I to III ratio in scratched dermal fibroblasts. Using a human ex vivo wound healing model, it was demonstrated that 1,25(OH)2D3, but not cholecalciferol, stimulated the rate of wound closure. In summary, this study has confirmed that human dermal fibroblasts express the transcriptional machinery for autocrine production of 1,25(OH)2D3, and a higher VDR expression suggests they are more responsive than keratinocytes. Changes in CYP and VDR expression in the presence of cholecalciferol, 25-hydroxyvitamin D3 or 1,25(OH)2D3 indicate fine-tuning of the bioavailability of vitamin D in the dermis after wounding. Down-regulation of α-SMA, MMP-2 secretion and the collagen type I to III ratio by 1,25(OH)2D3 highlight an important role for 1,25(OH)2D3 in modulating wound healing and the scarring process.

The purpose was to objectively measure the rate of healing of equine distal limb wounds when a 10% Natural Proprietary Compound (NPC) was compared to a topical antibacterial cream (1% silver sulfadiazine- SSD). Five horses had two wounds measuring 6.25cm2 created on the dorsomedial aspect of each limb. Two contralateral limbs were randomly chosen to be bandaged and the other two limbs were un-bandaged – with one limb of each group being treated with either NPC or SSD. On each limb the most proximal wound was left without topical treatment to act as a control. There was no significant difference between SSD and the compound evaluated in this study when either perimeter or area was assessed. Control wounds were significantly smaller than those treated with an ointment regardless of other variables, giving rise to a proposed location effect. Bandaging by day was significant for the time period approximating 2-5 weeks.

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This thesis is in three sections: an introductory chapter surveying the contributory factors which gave rise to Christian Science as a healing cult taking into account the life and peculiarities of its founder, Mrs. Baker, Glover, Patterson, Eddy; a chapter on Mrs. Eddy's contact with Mesmerism through Phineas P. Quimby who writings and methods she adopted as her own; and, finally, a chapter wherein the doctrine of "Mind Healing" is evaluated as to its validity, limitations and possibilities. It is contended that the healing taught and practiced by Christian Science is nothing new but merely a reintroduction, under a different name, of the ancient practice of hypnotic suggestion which is, without doubt, effective in healing functional diseases. It is further contended, however, that Christian Science claims to healing of all diseases is fraught with real danger to life since its methods cannot heal organic disease, neither can it claim divine healing since its very philosophy is a denial of true Christianity as also of true Science. / Thesis / Bachelor of Divinity (BD)

My thesis is an exploration of the emotional connection we have with architecture. The inspirations for the Grief and Healing Sanctuary were the healing experienced at quiet spaces of reflection and my father's stories as a Navy Vietnam shipboard combat veteran. I designed a building to provide a place for healing and to deal with grief. The building was designed for patients and their families being treated at the National Institutes of Health in Bethesda, Maryland. Not all families leave as they arrive. The families, many from out of town, need a place to reflect, pray, cry, or laugh. This need was reinforced by my father's stories of his transition from normal life to the extremes of combat to life back as a civilian. No one comes out unaffected, and there is not always a place to go and reflect. The Grief and Healing Sanctuary provides these spaces for all people who have these needs. / Master of Architecture

With advancements in medical technology, the mechanics of dying and death has changed significantly. Centuries ago, people mostly died of infectious diseases. From the time they were diagnosed, to the time of their death did not take long. Today, public health has improved remarkably. We have a better control over infectious diseases, but we have to deal with cancer and other chronic illnesses. The long period of treatment for such illnesses makes us spend a lot of our time in healthcare facilities such as hospitals, hospices, and care homes. Unfortunately, in many cases, these facilities do not pay much attention to emotional and spiritual needs of their patients and are mostly designed around their own institutional and technological needs. In that regard, these buildings become pretty awful places with no natural light and long corridors. Today, due to the nature of chronic diseases that we mostly deal with, hospice care facilities are becoming more popular. The idea of a hospice is to focus on quality of the place for families and patients who have already spent a lot of their time in a hospital setting. The goal is provide humane care for patients who do not have much time left, to make sure that they live the remainder of their lives as comfortably and as fully as possible. It is important to remember that when such facilities are designed for children, we need to pay extra attention to their unique needs. It is important to provide opportunities for children with terminal illnesses to continue to learn and grow. This thesis is exploration of an architectural setting in which children with a terminal prognosis would spend the last few weeks of their lives. Located in Old Town Alexandria, Virginia, this project takes advantage of the existing nature of the site to create an oasis for families who have gone through an exhausting battle with an untreatable disease. The goal is to shift the focus from curing to healing and to create a nurturing place that helps to bring normalcy back to the lives of patients and their families. / Master of Architecture

A successful landscape is one that allows people to feel comfortable within that landscape. Many people who live in an urban environment use gardens and parks as a way to balance their lives from the hard edge of what the world requires of them. That balance adds to the level of comfort and a decrease in stress. My thesis is to create a parking garage with that balance. A balance of hardscape with softscape, of practical uses with amenities, and of current methodology with progressive ideology. It will integrate parking and gardens, the static with the transitional. The proposal will create a balance between parking spaces where time is measured in hours with garden areas where time is measured in seasons. Thomas Jefferson said, "It takes time to persuade man to do even what is for his own good." This thesis is an example of that. Something that will take time for people, companies, municipalities and governing bodies to aspire to but that will, ultimately, be to the benefit of everyone. / Master of Landscape Architecture