Submitted by Luciana Ferreira (lucgeral@gmail.com) on 2016-02-04T07:54:13Z No. of bitstreams: 2 Dissertação - Celma Dias Borges - 2013.pdf: 8330340 bytes, checksum: a366dca28cfd3702224d099c0d56a472 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) / Approved for entry into archive by Luciana Ferreira (lucgeral@gmail.com) on 2016-02-04T07:56:57Z (GMT) No. of bitstreams: 2 Dissertação - Celma Dias Borges - 2013.pdf: 8330340 bytes, checksum: a366dca28cfd3702224d099c0d56a472 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) / Made available in DSpace on 2016-02-04T07:56:57Z (GMT). No. of bitstreams: 2 Dissertação - Celma Dias Borges - 2013.pdf: 8330340 bytes, checksum: a366dca28cfd3702224d099c0d56a472 (MD5) license_rdf: 23148 bytes, checksum: 9da0b6dfac957114c6a7714714b86306 (MD5) Previous issue date: 2013-12-20 / In addition to the common causes of death for both sexes, women are victimized by problems related to sexuality and reproduction. These problems become more severe for teenagers, as they are more likely to die than women greater than 20 years of age by a pregnancy-related, preventable death in most cases. The greater vulnerability of adolescents to these deaths is hinged to the material conditions of life and the rights recommended for this age group over the past decades depends one effective public politics. The aim of this study was to analyze maternal mortality in adolescents, in Goiânia, in the period 2002-2011. It is an observational, descriptive study conducted in the city of Goiânia, Brazil. The population included all maternal deaths of women aged between 10 and 49 years old in the city of Goiânia in the period 2002-2011, data collected from records of the death certificate and tokens Research Women and Maternal Death in the Municipal Health of Goiânia and structured in Microsoft Excel. The results showed no differences between the mortality profile of adolescents and women of all ages. Noteworthy is the proportion of unknown data for almost all variables, however, between the recorded data was prevalent age of 18, black color, low education and direct obstetric causes of maternal deaths. The conclusion from these findings is that age itself does not differ from the profile of maternal mortality among adolescents and women of all ages, but regardless of age where they occur, these deaths are a serious violation of human rights of women to be preventable in 92% of cases, and that the situation of vulnerability of adolescents to be recognized in practice as a condition for any teen is a victim of this type of death. / As causas de morte comuns a ambos os sexos, no entanto, as mulheres são vítimas de graves problemas ligados à sexualidade e à reprodução. Esses problemas se tornam mais graves para adolescentes, visto terem maior probabilidade de morrer do que uma mulher maior de 20 anos de idade por uma causa relacionada à gravidez. A maior vulnerabilidade das adolescentes para estas mortes está articulada às condições materiais de vida e os direitos preconizados para essa faixa etária ao longo das últimas décadas depende de políticas públicas efetivas. O objetivo deste estudo foi analisar a mortalidade materna em adolescentes, no município de Goiânia. Estudo observacional, descritivo. A população constitui-se pelos óbitos maternos de mulheres com idade entre 10 e 49 anos, ocorridos no município de Goiânia no período de 2002 a 2011, os dados coletados de fichas de Declaração de Óbito e fichas de Investigação de Óbito Feminino e Materno na Secretaria Municipal de Saúde de Goiânia e estruturados no programa Microsoft Excel. Os resultados não demonstraram diferenças entre o perfil de mortalidade de adolescentes e mulheres de todas as faixas etárias. Identificou-se grande proporção de dados ignorados para quase todas as variáveis, entretanto, entre os dados registrados foi prevalente a faixa etária de 18 anos, cor negra, baixa escolaridade e causas obstétricas diretas para os óbitos maternos. Concluiu-se que a faixa etária em si não difere o perfil de mortalidade materna entre adolescentes e mulheres de todas as idades, porém independente da faixa etária em que ocorram, essas mortes constituem uma grave violação dos direitos humanos das mulheres por serem evitáveis em 92% dos casos; e que a situação de vulnerabilidade das adolescentes precisa ser reconhecida na prática, como condição para que nenhuma adolescente seja vítima desse tipo de morte.

Orientadores: Jose Guilherme Cecatti, Maria Laura Costa do Nascimento / Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas / Made available in DSpace on 2018-08-26T00:58:50Z (GMT). No. of bitstreams: 1 Ferreira_EltonCarlos_M.pdf: 3220735 bytes, checksum: adb82ed562a5753986a41b8a54b80cb0 (MD5) Previous issue date: 2014 / Resumo: Objetivo: avaliar a distribuição dos partos segundo o Sistema de Classificação em Dez Grupos de Robson (RTGCS) explorando os dados da Rede Brasileira de Vigilância da Morbidade Materna Grave (RBVMMG) e do Hospital da Mulher (CAISM) da Universidade Estadual de Campinas (UNICAMP), Brasil; e comparação de ambos com os dados do estudo Global Survey da Organização Mundial de Saúde (WHO). Método: Foram realizadas duas abordagens. A primeira foi uma análise secundária de um estudo de corte transversal multicêntrico que ocorreu em 27 maternidades brasileiras de referência, localizadas nas cinco regiões do país e participantes da RBVMMG. Foi realizada a codificação dos dados para alocação de todas as mulheres segundo o RTGCS e as mulheres foram classificadas de acordo com o espectro clínico de gravidade e a condição subjacente de morbidade materna grave. Para a segunda abordagem, foi realizado um estudo de corte transversal, com avaliação das mulheres admitidas para parto no CAISM no período de janeiro 2009 a julho de 2013. As mulheres foram agrupadas segundo a RTGCS e, adicionalmente, a distribuição das mulheres entre os diferentes grupos foi comparada entre os casos que tiveram morbidade materna grave, operacionalmente definida pela necessidade de internação em unidade de terapia intensiva (UTI), com os demais casos sem complicações graves. Para as duas abordagens (RBVMMG e CAISM), realizou-se também uma comparação com resultados publicados de outro grande estudo, realizado em diferentes contextos e países, fundamentalmente com os dados para o Brasil, disponíveis no estudo Global Survey da WHO. Resultados: Para a RBVMMG, das 7247 mulheres que compuseram o estudo, 73.2% foram submetidas à cesariana (CS). O grupo 10, grupo com provável indicação de cesárea por complicação materna e/ou fetal, foi o mais prevalente com 33.9% e também aquele com maior contribuição para a taxa geral de cesárea, 28%. Os grupos que tiveram maior gravidade (¨near miss¨ e óbito materno) foram, em ordem decrescente, os grupos 7 e 9, o grupo 8 e o grupo 10. O grupo 3 teve um caso de resultado materno grave (¨near miss¨ + óbito materno) para cada 29 casos de condição potencialmente ameaçadora da vida. Nas mulheres desse grupo submetidas a CS, essa relação atingiu valores de 1:10. Em todos os grupos avaliados, a hipertensão foi o fator de gravidade mais frequente. Na segunda abordagem, foram admitidas 12.771 parturientes durante o período do estudo. A taxa de cesariana encontrada foi de 46.6%. O grupo 1 foi o mais prevalente com 28.1%, sendo o grupo 5 aquele que mais contribui para a taxa geral de cesárea (12.7%). Apresentaram, proporcionalmente, mais internação em UTI os grupos 10 (46.8%), 5 (13.3%) e 2 com 9.8%. Conclusões: O estudo evidenciou uma alta taxa de cesárea nas duas populações avaliadas e o uso do RTGCS mostrou-se útil, evidenciando grupos clinicamente relevantes com alta taxa de parto por cesárea. Estudos futuros serão necessários para melhor avaliar a associação entre cesárea e morbidade materna grave, assim como definir possíveis intervenções e a taxa de cesárea esperada para esse grupo específico de mulheres / Abstract: Objective: To evaluate the distribution of delivering women according to the Robson¿s Ten Group Classification System (RTGCS) exploring the data from the Brazilian Network for the Surveillance of Severe Maternal Morbidity (RBVMMG) and from a tertiary hospital (CAISM), University of Campinas, Brazil; comparing both data with that from the WHO Global survey. Method: Two approaches were proposed. The first, a secondary analysis of a database obtained from a multicenter cross-sectional study taking place in 27 referral obstetric units located in the five geographical regions of Brazil, members of the Brazilian Network for the Surveillance of Severe Maternal Morbidity (RBVMMG), was carried out. For this analysis, data was organized following information necessary to classify all women into one of the RTGCS and cases from each of the 10 groups were classified according to case severity and underlying cause of severe morbidity. Subsequently, certain Robson groups were subdivided for further analysis. For the second approach, a cross-sectional study of data from women delivering at CAISM from January 2009 to July 2013 was carried out. Women were grouped according to RTGCS and, additionally, the distribution of women among the different groups was compared between cases who had severe maternal morbidity (SMM), operationally defined by intensive care unit (ICU) admission, with the other cases without severe complications. For both approaches (RBVMMG and CAISM), patients distributed among groups were compared to another Brazilian study population, available on the WHO Global Survey study. Results: For RBVMMG, among the 7247 women considered, 73.2% underwent cesarean section (CS). Group 10 had the highest prevalence rate (33.9%), also contributing most significantly (28%) to the overall CS rate. Groups associated with a severe maternal outcome (maternal ¨near miss¨ or maternal death), in decreasing order were: groups 7 and 9, 8 and 10. Group 3 had one case of severe maternal outcome (maternal ¨near miss¨ + maternal death) for every 29 cases of potentially life-threatening conditions. When evaluating only women undergoing CS in this group, ratios of 1:10 were achieved, indicating a worse outcome. Among all groups evaluated, hypertension was the most common condition of severity. For CAISM, of the 12771 women, 46.6% underwent CS. Group 1 had the highest prevalence rate (28%) and Group 5 contributed most significantly to overall CS rates. ICU admission was proportionally higher in groups 10 (46.8%), 5 (13.3%) and 2 with 9.8%.Conclusions: The study demonstrated a high cesarean section rate in the two populations studied and the use of RTGCS proved to be extremely useful, showing clinically relevant groups with high rates of cesarean section. Future studies are needed to better evaluate the association between cesarean section and severe maternal morbidity, as well as to define possible interventions and the expected cesarean section rate for this particular group of women / Mestrado / Saúde Materna e Perinatal / Mestre em Ciências da Saúde

Ghana, a low-income developing country in sub-Saharan Africa is experiencing low maternal health service utilization and high rates of maternal mortality, especially in the rural areas. The Talensi-Nabdam District is one of the poorest and most remote districts in Ghana. The reproductive health status of women in the most remote communities in this District is poor. Dialogue about women’s reproductive health care needs in Ghana have been influenced by health care authorities, professionals, researchers and experts’ perceptions. The purpose of this ethnographic research was to explore rural Ghanaian women’s experiences of seeking reproductive health care from their own perspectives. The study was based on data collected from participant observations, unstructured face-to-face interviews and focus group discussions. A total of 27 women of varying socio-demographic backgrounds participated in the study. Interviews were conducted at locations of the women’s choice and in women’s local dialect. Data were translated and transcribed verbatim, and analyzed thematically. Four major themes emerged from the findings: submitting to the voices of family, women’s experiences of receiving nursing care, the community of gossip, and gaining voice. The findings of this study have implications for nursing practice, education and nursing inquiry. Awareness of barriers that rural women encounter in meeting their reproductive health care needs among health care providers is important in facilitating positive health care seeking behaviours. Nurse educators should orient themselves to the challenges to meeting women’s health care needs, and include in culturally sensitive approaches in nursing education programs. Further research is needed to investigate strategies that will enhance women’s reproductive health care seeking behaviours in rural settings and to focus on women’s perspectives in particular. In addition, research is needed to examine nurses’ perspectives on factors that influence quality care delivery to address women’s reproductive health issues. / Health and Social Development, Faculty of (Okanagan) / Nursing, School of (Okanagan) / Graduate

Abstract Background: Maternal mortality is one of the most sensitive indicators of the health disparities between poorer and richer nations. It is also one of the most difficult health outcomes to measure reliably. In many settings, major challenges remain in terms of both measuring and reducing maternal mortality effectively. This thesis aims to quantify overall levels, identify specific causes, and evaluate local interventions in relation to efforts to reduce maternal mortality in Tigray Region, Northern Ethiopia, thereby providing a strong empirical basis for decision making by the Tigray Regional Health Bureau using methods that can be scaled at national level.   Methods: This study employed a combination of community-based study designs to investigate the level and determinants of maternal mortality in six randomly selected rural districts of Tigray Region. A census of all households in the six districts was conducted to identify all live births and all deaths to women of reproductive age occurring between May 2012 and September 2013. Pregnancy-related deaths were screened through verbal autopsy with the data processed using the InterVA-4 model, which was used to estimate Maternal Mortality Ratio. To identify independent determinants of maternal mortality, a case-control study using multiple logistic regression analysis was done, taking all pregnancy-related deaths as cases and a random sample of geographical and age matched mothers as controls. Uptake of ambulance services in the six districts was determined retrospectively from ambulance logbooks, and the trends in pregnancy-related death were analyzed against ambulance utilization, distance from nearest health center, and mobile network coverage at local area level. Lastly, implementation of the Family Folder paper health register, and its potential for accurately capturing demographic and health events, were evaluated using a capture-recapture assessment.   Results: A total of 181 deaths to women of reproductive age and 19,179 live births were documented from May 2012 to April2013. Of the deaths, 51 were pregnancy-related. The maternal mortality ratio for Tigray region was calculated at 266 deaths per 100,000 live births (95% CI 198-350), which is consistently lower than previous “top down” MMR estimates. District–level MMRs showed strong inverse correlation with population density (r2 = 0.86). Direct obstetric causes accounted for 61% of all pregnancy–related deaths, with hemorrhage accounting for 34%. Non-membership in the voluntary Women’s Development Army (AOR 2.07, 95% CI 1.04-4.11), low husband or partner involvement during pregnancy (AOR 2.19, 95% CI 1.14-4.18), pre-existing history of other illness (AOR 5.58, 95% CI 2.17-14.30), and never having used contraceptives (AOR 2.58, 95% CI 1.37-4.85) were associated with increased risk of maternal death in a multivariable regression model. In addition, utilization of free ambulance transportation service was strongly associated with reduced MMR at district level. Districts with above-average ambulance utilization had an MMR of 149 per 100,000 LB (95% CI: 77-260) compared with 350 per 100,000 (95% CI: 249-479) in districts with below average utilization. The Family Folder implementation assessment revealed some inconsistencies in the way Health Extension Workers utilize the Family Folders to record demographic and health events.   Conclusion: This work contributes to understanding the status of and factors affecting maternal mortality in Tigray Region. It introduces a locally feasible approach to MMR estimation and gives important insights in to the effectiveness of various interventions that have been targeted at reducing maternal mortality in recent years.

Maternal mortality is a critical area of concern globally, despite the availability of accessible preventive measures. The role of sociodemographic and service delivery factors in maternal mortality in the Accra Metropolitan Area of Ghana are important to examine. As part of the United Nations (UN) Millennium Campaign, the UN implemented 8 Millennium Development Goals (MDGs); maternal mortality reduction by 75% between 1990 and 2015 was among the fundamental MDGs to be achieved by 2015. The purpose of this case-control study was to use secondary data to assess the relationships between sociodemographic variables, service delivery factors, and maternal mortality among 8,171 women of reproductive age (15-45 years) living in the Greater Accra metropolitan area in Ghana. The health belief model and social cognitive theory provided the theoretical framework to interpret the study findings. Particularly, income (p = .023), primary (p = .035) and secondary (p = .002) education, and health insurance (p = .008) were significantly associated with maternal-related mortality. However, for survival outcome, health insurance (p = .003), prenatal care (p = .001), and presence of a skilled attendant at delivery (p = .020) were significant factors. These study results provide support for the significant effects of sociodemographic and service delivery factors on maternal mortality and survivorship in the Greater Accra metropolitan area in Ghana. The results of this study could enhance educational and outreach programs designed to lower maternal mortality rate. Further research needs to be done to advance knowledge and practice in health delivery services and public health education with respect to the importance of sociodemographic and service delivery characteristics.

Problem: Zambia has one of the highest maternal mortality ratios in the world. Risks of serious complications during childbirth and associated maternal morbidity and mortality can be mitigated by improving access to skilled birth attendants and emergency obstetric and newborn care (EmONC) in facilities when complications arise. In 2012, the Saving Mothers Giving Life (SMGL) initiative was launched in Kalomo District, Zambia, to reduce maternal deaths. Methods: This study assessed the impact of SMGL in Kalomo District on rates of facility delivery, delivery with a skilled birth attendant, and facility-level changes in the provision of maternity and newborn care during the first learning phase, 2012–2013. Changes in neonatal mortality were also assessed. A mixed-methods approach utilized a quasi-experimental pre-post nonequivalent comparison group design using household data (n=21,680 women) and health facility assessments (n=77) including EmONC signal functions. Data were collected from February 2011–October 2013, before and during SMGL program implementation, in the intervention district and a comparison area. A qualitative inquiry with key informants (n=26) was then conducted in September 2014. Results: There was a 49% relative increase in the odds of facility-based birth during SMGL in Kalomo relative to comparison districts (OR 1.49, 95% CI: 1.21–1.77), controlling for covariates. There was no significant change in delivery with a skilled birth attendant. Newborn mortality in Kalomo decreased significantly (4.3% to 2.6%, p<0.01), even when controlling for covariates, with no change in comparison. EmONC signal functions increased from a mean of 2.7 to 3.9 (p=0.003) per facility in Kalomo, with no change in the comparison area. Most facility-level changes related to newborn care. Informants attributed impacts primarily to community mobilization by Safe Motherhood Action Group volunteers and clinical mentorship. Conclusion: SMGL positively influenced demand for facility deliveries. Data indicate a limited measurable change in supply-side indicators of provision of intra-partum maternity care, while improving neonatal survival. Interviews suggested that mentoring existing staff might be responsible for improved care and referrals. Phase 2 should focus on strengthening human resources to increase access to skilled delivery and strategies to improve communication and transport to facilitate timely referral of emergency cases.

MSc (Statistics) / Department of Mathematics and Natural Sciences

Although efforts have been made towards improving the health of children across the globe with notable results, neonatal tetanus (NNT) remains a major contributor to the neonatal death rates in Nigeria. This problem calls for a concerted effort by the government to achieve the revised global NNT elimination deadline of 2015. The purpose of this cross-sectional quantitative study using secondary data was to establish the prevalence of NNT in Nigeria's northeast region and to ascertain if there was any significant difference in frequency of antenatal care (ANC), trained traditional birth attendants (TBAs), and umbilical cord treatments, using single sample proportions test and chi-squared tests of independence. The framework for this research was the theory of planned behavior. The participants (N = 312) were mothers of NNT babies. In spite a continual decline in the NNT cases between 2010 (26%) and 2013 (9%), the prevalence rate of NNT was unacceptably high at 28.815%. Also, significant differences existed as mothers who gave birth to NNT babies received significantly fewer or no ANC (p < 0.001), received significantly fewer or no attention from TBAs (p < 0.001), and reported significantly fewer incidences of proper umbilical cord treatments (p < 0.001). The chi-squared tests of independence resulted in significant differences in the frequencies of mothers who received ANC between Nigerian provinces (p < 0.001) and mothers who had their baby's umbilical cord treated (p = 0.005). This study will contribute to social change by guiding health care policy makers and immunization program managers on maternal and newborn health care services and indicate ways to build capacity of the TBAs for safe home delivery/hygienic handling of umbilical cord of newborns.

La mortalité maternelle est considérée depuis quelques années comme un problème de santépublique au Sénégal ; ce qui a engendré pendant ces dernières décennies, un ensemble d’actionsparfois pertinentes, mais dont la mise en oeuvre est très souvent discutée, comme c’est le cas dansde nombreux pays africains.En 2010, le ratio de mortalité maternelle du pays est estimé à 392 décès maternels pour 100 000naissances vivantes selon le rapport de l’enquête démographique et de santé (EDS). Ce niveau resteélevé en dépit d’une hausse considérable du recours à l’assistance à l’accouchement.L’assistance médicale à l’accouchement qualifiée, définie comme « le processus par lequel unefemme reçoit des soins adéquats durant le travail, l’accouchement et le post-partum précoce », estapparue dans plusieurs études comme un déterminant-clé dans le processus de réduction de la mortalitématernelle.Deux conclusions principales sont obtenues à partir de nos analyses.D’une part, la très forte hausse du recours à l’assistance médicale à l’accouchement observée aucours de la première décennie des années 2000 a été sanctionnée par une baisse régulière, mais modérée,de la mortalité maternelle. D’autre part, cette faible baisse s’explique par une offred’assistance médicale à l’accouchement excessivement centrée sur des sages-femmes dont les qualificationssont hétérogènes et trop souvent limitées. Elle s’explique aussi par des infrastructures encoretrop peu adaptées à la gestion des urgences obstétricales.En effet, malgré tous les progrès accomplis dans ce domaine, il reste encore une marge importantepour poursuivre l’accès à un accouchement assisté. C’est en particulier le cas dans les campagnes,chez les femmes les plus jeunes, celles qui ont reçu une faible instruction et qui dépendent exagérémentde leurs conjoints. De ce fait, il serait intéressant de mener des politiques de sensibilisationdu côté des hommes.Au final, les enjeux futurs de l’assistance médicale à l’accouchement au Sénégal continuent à combinerdes problèmes d’offre et des problèmes de demande malgré les progrès accomplis dans cedomaine. / Maternal mortality is considered for several years as a public health problem in Senegal; which resultedin recent decades of a set of relevant actions sometimes, but the implementation is very oftendiscussed, as is the case in many African countries.In 2010, the maternal mortality ratio in the country is estimated at 392 maternal deaths per 100,000live births according to the report of the Demographic and Health Survey (DHS). This level remainshigh despite of a significant increase in the use of Delivery Assistance.The qualified medical assistance in childbirth, defined as "the process by which a woman receivesadequate medical care during labor, delivery and the early postpartum," has appeared in severalstudies as a key determinant in the maternal mortality reduction process.We can note two main conclusions from our analysis.First, the very strong increase in the use of medical assistance in delivery which has been observedin the first decade of the 2000s was sanctioned by a regular but moderate decline in maternal mortality.Then, this small decrease is due to a medical assistance in childbirth entirely performed bymidwives whose qualifications are heterogeneous and often limited. It is also explained by infrastructureswhich are not adapted to the management of obstetric emergencies.In fact, despite all the progress made in this field, there still are significant things to do before accessingto assisted delivery. This is particularly the case in rural areas, among younger women,those who received low education and who depend excessively on their husbands. Therefore, itwould be interesting to make aware of men on this issue.In the end, the future challenges of Assisted Reproduction Technology (ART) in Senegal continueto combine problems of supply and demand problems despite the progress made in this field.

Mozambique is in the process of setting up maternity waiting homes (MWHs) in an attempt to improve access of women living in remote areas. It is expected that MWHs will increase institutional deliveries and consequently, decrease maternal mortality caused by the delay in reaching obstetric care. However, no evidence for this assumption has been found in the literature. The objective of this research was, using Geographical Information Systems (GIS), to assess the impact of MWHs in increasing institutional deliveries coverage. GIS technology is a valuable methodology to analyse access, especially in contexts where official records are weak. An ecological study, using a sample of 28 health facilities, was conducted in six districts in northern Mozambique. The findings suggest that MWHs could contribute to increasing institutional deliveries coverage in a range of 4% to 2 %. However, they do not appear to increase access of women living in remote areas. / M.A. (Public Health)