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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
provided by the
Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
Search results
Showing 381 to 390 of 504 (0.042 seconds)| 381 |
THE ROLE OF IL-¿¿1 RECEPTOR-¿¿ASSOCIATED KINASE 4 IN MICROGLIAL ACTIVATION IN ALZHEIMER’S DISEASECameron, Brent D. 07 March 2013 (has links)
No description available.
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| 382 |
Gene regulatory mechanisms underlying microglial dysfunction in Alzheimer’s diseaseDaily, Kylene Patricia 19 September 2022 (has links)
No description available.
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| 383 |
Interleukin-1 signaling in the stressed CNS: From microglial source to neuronal destinationDiSabato, Damon J. January 2021 (has links)
No description available.
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| 384 |
Role of P2X7 Receptors in Immune Responses During NeurodegenerationOliveira-Giacomelli, Ágatha, Petiz, Lyvia Lintzmaier, Andrejew, Roberta, Turrini, Natalia, Silva, Jean Bezerra, Sack, Ulrich, Ulrich, Henning 27 March 2023 (has links)
P2X7 receptors are ion-gated channels activated by ATP. Under pathological conditions,
the extensive release of ATP induces sustained P2X7 receptor activation, culminating
in induction of proinflammatory pathways with inflammasome assembly and cytokine
release. These inflammatory conditions, whether occurring peripherally or in the central
nervous system (CNS), increase blood-brain-barrier (BBB) permeability. Besides its well-known involvement in neurodegeneration and neuroinflammation, the P2X7 receptor
may induce BBB disruption and chemotaxis of peripheral immune cells to the CNS,
resulting in brain parenchyma infiltration. For instance, despite common effects on
cytokine release, P2X7 receptor signaling is also associated with metalloproteinase
secretion and activation, as well as migration and differentiation of T lymphocytes,
monocytes and dendritic cells. Here we highlight that peripheral immune cells mediate
the pathogenesis of Multiple Sclerosis and Parkinson’s and Alzheimer’s disease, mainly
through T lymphocyte, neutrophil and monocyte infiltration. We propose that P2X7
receptor activation contributes to neurodegenerative disease progression beyond its
known effects on the CNS. This review discusses how P2X7 receptor activation
mediates responses of peripheral immune cells within the inflamed CNS, as occurring
in the aforementioned diseases.
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The Role of Neuroinflammation in the Pathogenesis of Amyotrophic Lateral SclerosisFrakes, Ashley E. January 2014 (has links)
No description available.
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| 386 |
Cytokine expression, cytoskeleton organization, and viability of SIM-A9 microglia exposed to Staphylococcus aureus-derived lipoteichoic acid and peptidoglycanRoberts, Erin January 2017 (has links)
No description available.
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| 387 |
HSV-1 Infection of C3H Central Nervous System Cell LinesVan Buren, Lauren Kay 27 September 2007 (has links)
No description available.
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| 388 |
Alzheimer's disease pathology in aged chimpanzeesEdler, Melissa K. 26 July 2016 (has links)
No description available.
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| 389 |
Studies on the role of Cofilin signaling in Hemin induced Microglial activationBin Sayeed, Muhammad Shahdaat 22 December 2016 (has links)
No description available.
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| 390 |
Examination Of A Post-Stroke Drug Treatment For Its Effect On Blood Brain Barrier Permeability, And Gene Expression Changes In The Peri-Infarct RegionPatel, Ankita Anil 29 August 2016 (has links)
No description available.
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