Evidence suggests that certain genotypic variants associated with novelty-seeking and aggressiveness, such as the 7-repeat dopamine D4 receptor variant (DRD4-7R), short (s) allele of the serotonin transporter (5-HTT), and the low-activity variant of the MAOa promoter (MAOa-L), are more prevalent in human groups that radiated out of Africa than human groups that remained in Africa. Rhesus macaques (Macaca mulatta), like humans, are a widespread species of primates that needed to adapt to different regional environments with one group, Indian-derived rhesus macaques, largely occupying predictable and resource-rich environments, while the other group, the Chinese-derived rhesus macaques, has come to occupy less predictable and resource-abundant environments. Rhesus macaques possess orthologues of these trait-related genes, making it possible to compare the frequency of genotypes associated with these traits between members of two strains. DNA was obtained from N=212 rhesus macaques (n=54 Chinese-derived, n=158 Indian-derived) and genotyped for DRD4 (n=98), 5-HTT (n=190), and MAOA (n=97). Analyses showed that Chinese-derived subjects exhibited higher frequencies of the DRD4-7R and 5-HTT-s-allele when compared to Indian-derived subjects. There were no strain differences in MAOA-L genotype groupings, but the Chinese-derived subjects exhibited a more frequent high-activity (MAOA-H-6R) allele when compared to the Indian-derived subjects. The results suggest that the Chinese-derived rhesus macaques possess a higher frequency of alleles associated with novelty-seeking, impulsivity, and aggressiveness compared to their Indian-derived peers and that those genotypically-mediated traits may have beneficial to both humans and rhesus macaques as they spread into novel and unfamiliar environments.

Network usage is an important quality metric for mobile apps. Slow networks, low monthly traffic quotas and high roaming fees restrict mobile users’ amount of usable Internet traffic. Companies wanting their apps to stay competitive must be aware of their network usage and changes to it. Short feedback loops for the impact of code changes are key in agile software development. To notify stakeholders of changes when they happen without being prohibitively expensive in terms of manpower the change detection must be fully automated. To further decrease the manpower overhead cost of implementing network usage change detection the system need to have low configuration requirements, and keep the false positive rate low while managing to detect larger changes. This thesis proposes an automated change detection method for network activity to quickly notify stakeholders with relevant information to begin a root cause analysis after a change in the network activity is introduced. With measurements of the Spotify’s iOS app we show that the tool achieves a low rate of false positives while detecting relevant changes in the network activity even for apps with dynamic network usage patterns as Spotify. / Nätverksaktivitet är ett viktigt kvalitetsmått för mobilappar. Mobilanvändare begränsas ofta av långsamma nätverk, låg månatlig trafikkvot och höga roamingavgifter. Företag som vill ha konkurrenskraftiga appar behöver vara medveten om deras nätverksaktivitet och förändringar av den. Snabb återkoppling för effekten av kodändringar är vitalt för agil programutveckling. För att underrätta intressenter om ändringar när de händer utan att vara avskräckande dyrt med avseende på arbetskraft måste ändringsdetekteringen vara fullständigt automatiserad. För att ytterligare minska arbetskostnaderna för ändringsdetektering av nätverksaktivitet måste detekteringssystemet vara snabbt att konfigurera, hålla en låg grad av felaktig detektering samtidigt som den lyckas identifiera stora ändringar. Den här uppsatsen föreslår ett automatiserat förändringsdetekteringsverktyg för nätverksaktivitet för att snabbt meddela stakeholders med relevant information för påbörjan av grundorsaksanalys när en ändring som påverkar nätverksaktiviteten introduceras. Med hjälp av mätningar på Spotifys iOS-app visar vi att verktyget når en låg grad av felaktiga detekteringar medan den identifierar ändringar i nätverksaktiviteten även för appar med så dynamisk nätverksanvändning som Spotify.

Inferences from scientific success to the approximate truth of successful theories remain central to the most influential arguments for scientific realism. Challenges to such inferences, however, based on radical discontinuities within the history of science, have motivated a distinctive style of revision to the original argument. Conceding the historical claim, selective realists argue that accompanying even the most revolutionary change is the retention of significant parts of replaced theories, and that a realist attitude towards the systematically retained constituents of our scientific theories can still be defended. Selective realists thereby hope to secure the argument from success against apparent historical counterexamples. Independently of that objective, historical considerations have inspired a further argument for selective realism, where evidence for the retention of parts of theories is itself offered as justification for adopting a realist attitude towards them. Given the nature of these arguments from success and from retention, a reasonable expectation is that they would complement and reinforce one another, but although several theses purport to provide such a synthesis the results are often unconvincing. In this paper I reconsider the realist's favoured type of scientific success, novel success, offer a revised interpretation of the concept, and argue that a significant consequence of reconfiguring the realist's argument from success accordingly is a greater potential for its unification with the argument from retention.

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Knowing when one does not know is crucial in decision making. By estimating uncertainties humans can recognize novelty both by intuition and reason, but most AI systems lack this self-reflective ability. In anomaly detection, a common approach is to train a model to learn the distinction between some notion of normal and some notion of anomalies. In contrast, we let the models build their own notion of normal by learning directly from the data in a self-supervised manner, and by introducing estimations of model uncertainty the models can recognize themselves when novel situations are encountered. In our work, the aim is to investigate the relationship between model uncertainty and anomalies in time series data. We develop a method based on a recurrent autoencoder approach, and we design an anomaly score function that aggregates model error with model uncertainty to indicate anomalies. Use the Monte Carlo Dropout as Bayesian approximation to derive model uncertainty. Asa proof of concept we evaluate our method qualitatively on real-world complex time series using stock market data. Results show that our method can identify extreme events in the stock market. We conclude that the relation between model uncertainty and anomalies can be utilized for anomaly detection in time series data.