In the past, most research on soil mechanical properties was carried out for cohesionless soils in the fields of civil and geotechnical engineering. Little research has been carried out for mechanical properties of agricultural soil, which are essential for designing soil engaging tools in agriculture. In this study, unconsolidated undrained triaxial compression tests were performed to study the effects of moisture level and confining pressure on a sandy loam soil. The soil specimens tested had three moisture levels, and they were high (27-29% d.b.), medium (19-21% d.b.) and low (9-11% d.b.). The confining pressures used for the triaxial tests were 50, 100, and 150 kPa. Soil specimen was loaded at a strain rate of 1%/min. Measurements from the tests included stress-strain curve, shear strength, Young’s modulus, Poisson’s ratio, angle of internal friction, and cohesion. A model was developed using the Discrete Element Method (DEM) and computed by Particle Flow Code in three dimensions (PFC3D), a common DEM software. The model simulated the triaxial compression tests, and the model specimen was an assembly of 5-mm spherical particles which were defined by a set of micro parameters. During simulations, soil shear strength was monitored under different confining pressures. Through sensitivity analysis, it was found that most of the micro parameters affected the simulated soil shear strengths and the stress-strain behaviours. The most influential micro parameter was particle friction coefficient. This micro parameter was calibrated with the data from triaxial tests for different combinations of soil moisture levels and confining pressures. The calibrated particle friction coefficients varied from 0.2 to 1.0. The calibrations were done through matching the shear strengths between simulations and measurements, and the relative errors ranged between 0 and 6 %. / October 2015

Le contrôle précis des boucles de régulation existantes sur une machine frigorifique est essentiel à son bon fonctionnement. Il existe plusieurs méthodes de régulation parmi lesquelles on retrouve la plus ancienne et la plus connue : la commande PID (Proportionnelle, Intégrale et Dérivée). Malgré la simplicité apparente des relations mises en jeu, le régulateur PID est assez délicat à ajuster sur des processus présentant de fortes perturbations comme les installations frigorifiques. L'objectif du travail présenté est de mettre en œuvre une commande prédictive fonctionnelle (PFC) afin de réguler la surchauffe en sortie d'évaporateur, la pression de condensation et la puissance frigorifique sur une installation munie d'un compresseur à vitesse variable. L'utilisation d'une commande PFC nécessite de réaliser une prédiction de l'évolution à venir de la sortie du procédé. C'est un modèle interne qui fait office de modèle de connaissance. En assimilant le procédé à un système du premier ordre, la mise en œuvre de cette commande ne nécessite que trois paramètres : un gain statique, une constante de temps et un retard pur. L'originalité de la démarche développée a consisté à réaliser une modélisation physique de la machine afin de déterminer les paramètres précédents par une approche macroscopique. Une bibliothèque de modèles physiques a été élaborée permettant de simuler le comportement de différents évaporateurs, condenseurs, compresseurs ou vannes de détente. La commande développée a ensuite été implantée sur un automate industriel programmable et des expériences ont été réalisées sur deux machines différentes. La première est constituée de deux échangeurs à tubes et calandre et d'un compresseur à pistons, alors que la seconde comprend un évaporateur à plaques, une batterie à ailettes et un compresseur à vis.

A single-phase, buck-boost based, dual-output AC-DC converter is studied in this thesis. The converter has two DC outputs with opposite polarities, which share the same ground with the input power line. The power stage performance, including the input filter, is studied and procedure to select power components is given. The circuit model is analyzed to develop appropriate control. Zerocrossing distortion of the source input current is addressed and a solution is proposed. Experimental results are satisfactory in that a high power factor line current results for steady-state operation.

Made available in DSpace on 2014-12-17T14:55:42Z (GMT). No. of bitstreams: 1 LucianoPSJ_DISSERT.pdf: 6664942 bytes, checksum: fc1840aaaecdac8b8558e271f979adbf (MD5) Previous issue date: 2009-04-17 / This work deals with the development of an experimental study on a power supply of high frequency that provides the toch plasmica to be implemented in PLASPETRO project, which consists of two static converters developed by using Insulated Gate Bipolar Transistor (IGBT). The drivers used to control these keys are triggered by Digital Signal Processor (DSP) through optical fibers to reduce problems with electromagnetic interference (EMI). The first stage consists of a pre-regulator in the form of an AC to DC converter with three-phase boost power factor correction which is the main theme of this work, while the second is the source of high frequency itself. A series-resonant inverter consists of four (4) cell inverters operating in a frequency around 115 kHz each one in soft switching mode, alternating itself to supply the load (plasma torch) an alternating current with a frequency of 450 kHz. The first stage has the function of providing the series-resonant inverter a DC voltage, with the value controlled from the power supply provided by the electrical system of the utility, and correct the power factor of the system as a whole. This level of DC bus voltage at the output of the first stage will be used to control the power transferred by the inverter to the load, and it may vary from 550 VDC to a maximum of 800 VDC. To control the voltage level of DC bus driver used a proportional integral (PI) controller and to achieve the unity power factor it was used two other proportional integral currents controllers. Computational simulations were performed to assist in sizing and forecasting performance. All the control and communications needed to stage supervisory were implemented on a DSP / O presente trabalho trata do desenvolvimento de um estudo experimental sobre uma fonte de alimenta??o de alta freq??ncia que alimentar? a tocha pl?smica a ser implementada no projeto PLASPETRO, o qual consta de dois conversores est?ticos desenvolvidos com o uso de transistores - Insulated Gate Bipolar Transistor (IGBT). Os drivers utilizados no controle dessas chaves s?o acionados por um controlador de sinal digital - Digital Signal Processor (DSP) atrav?s de fibras ?pticas a fim de reduzir problemas com interfer?ncia eletromagn?tica - Electromagnetic interference (EMI). O primeiro consiste de um est?gio pr?-regulador na forma de um conversor CA-CC boost trif?sico com corre??o de fator de pot?ncia, tema principal deste trabalho, enquanto o segundo consiste na fonte de alta frequ?ncia propriamente dita. Um inversor s?rie-ressonante composto por 4 (quatro) c?lulas inversoras operando a uma frequ?ncia de cerca de 115 kHz cada, em modo de comuta??o suave, alternando-se para fornecer ? carga (tocha de plasma) uma corrente alternada com uma frequ?ncia de 450 kHz. O primeiro est?gio tem a fun??o de fornecer ao inversor s?rie-ressonante uma tens?o CC de valor controlado a partir da rede de alimenta??o disponibilizada pelo sistema el?trico da concession?ria, al?m de corrigir o fator de pot?ncia do sistema como um todo. Esse n?vel CC de tens?o no barramento de sa?da do primeiro est?gio ser? utilizado para o controle da pot?ncia transferida pelo inversor ? carga, podendo variar desde 550Vcc at? um valor m?ximo de 800Vcc. Para controlar o n?vel de tens?o do barramento CC utilizou-se um controlador Proporcional Integral (PI) e para atingir o fator de pot?ncia unit?rio utilizou-se dois outros PIs para controle das correntes em referencial estacion?rio. Simula??es computacionais foram realizadas para auxiliar no dimensionamento e previs?o de performance. Todo o controle e comunica??es necess?rias ao est?gio supervis?rio foram implementadas em um DSP

The importance of investigating Emotion Regulation (ER) may be self-evident, given that emotions have a substantial impact on our daily lives. ER encompasses set of processes that people go through in order to cultivate their feelings that arise at the moment and produce some response. Brain-imaging studies of ER have broadly focused on examining cognitive strategies, such as reappraisal, in order to understand underlying variables that contribute to the development of this particular process of emotions. The main focus in this paper was to summarize some of the observation done by functional Magnetic Resonance Imaging (fMRI) on neural processes underlying cognitive reappraisal. Furthermore, the paper will discuss some of these experiments that have been made through the last 15 years in the field where indications have been somewhat confusing when it comes to certain aspects of presented data, especially in comparison with other studies. Finally, a brief overview and some of the significant contributions, such as a process model of ER, to the field of ER have been presented and discussed. Cognitive reappraisal has been shown to effectively down-regulate subjective emotional experience. Even though many studies have been performed in measuring brain-activity when engaging in cognitive reappraisal, a unified and accepted agreement has yet not been found. In broader terms, brain-responses when engaging in cognitive reappraisal seem to operate in a particular manner where different parts of prefrontal and parietal cortex execute control over subcortical regions, such as amygdala.

Emotions have a remarkable capacity to mobilize an individual and shape a person’s behavior in order to ultimately lead to a higher wellbeing. The importance of emotions is further emphasized by pathological cases of people who suffer from an inability to normally regulate their emotional life, such as people who suffer from major depression disorder (MDD), eating disorders, or borderline personality disorder. Given the central role emotions play in our lives, it is very easy to understand the great interest cognitive neuroscientists have in this research field. Emotions have been approached in the last decades from different angles and as such, distinct theories arose. The goal of this study is to give a comprehensive overview of the emotion theories that exist, with a focus on three of the fastest developing cognitive theories of emotions: Frijda’s action-readiness, Russell’s core affect and the communicative theory. Additionally, the neural correlates of emotions will be discussed, focusing on the role of amygdala in the negative emotion of fear. Neuroimaging studies that reveal a correlation between the amygdala and emotions, fear in particular, will be described. Given that the ability of self-regulation is crucial for the achievements of our aims and goals, fMRI studies designed to investigate neural the underpinnings of emotion regulation will be presented. The process of cognitive reappraisal will be used to point towards the brain regions that act as down-regulators for the activity of amygdala while processing negatively valenced stimuli.

This diploma thesis is focused on the LLC resonant power supply with power factor correction. The first part of the thesis is focused on a selection of a suitable controller for the control of this source. Here the emphasis is mainly on efficiency and EMC. The thesis also deals with the design of the scheme and the selection of suitable components. The thesis contains the design of the LLC power supply itself and also the power factor correction circuit - PFC.

Cognitive symptoms, considered in conjunction both with their regional brain and biomarkers as well as affective, attributional and neurode-velopmental components, demonstate ever-increasing complexity to facilitate conceptualization yet, unavoidably, bedevil diagnosis in neuropsychiatry even before considerations of the enigmatic processes in memory, such as executive function and working memory, are drawn into the myriads of equations that await remedial interpretations. Prefrontal and limbic regions of the brain are involved in a diversity of expressions of cognition, normal or dysfunctional, at synaptic, intracellular and molecular levels that mobilize a concatenation of signaling entities. Serotoninergic neurotransission at prefrontal regions directs cogntive-affective entities that mediate decision-making and goal-directed behaviour. Clinical, non-clinical and basic studies challenge attempts to consolidate the multitude of evidence in order to obtain therapeutic notions to alleviate the disordered status of the diagnosed and yet-to-be diagnosed individuals. Locus of control, a concept of some utility in health-seeking procedures, is examined in three self-report studies from the perspective of a cognitive-emotional situation through observations of ordinary, 'healthy' young and middle-aged individuals, to assess the predictors of internal and external locus of control. A notion based on high level executive functioning in the dorsolateral prefrontal cortex (DLPFC) in individuals characterised by internal locus of control is contrasted with a hypofunctional executive DLPFC, characterising individuals that express an external locus of control, is discussed.

Mycobacterium tuberculosis (Mtb) is the causative agent of Tuberculosis (TB), a life-threatening disease primarily affecting the lungs that infects about one third of the world's population and causes 1.3 million deaths annually. It is estimated that TB has been infecting humans for around 70,000 years and has killed more people than any other infectious disease. The highly effective, persistent, and multifaceted virulence strategies that have allowed Mtb to continue to spread and thrive for so long are still poorly understood at the molecular level. This lack of knowledge contributes to ongoing challenges to curing TB. Although drugs capable of killing Mtb exist, even strains that are susceptible to these drugs remain so difficult to treat that stringent six- to nine-month courses of four-drug cocktails are required. Practical difficulties in administering full treatments and patient noncompliance have contributed to a rise in drug-resistant TB cases globally. To combat this increasing world health problem, new antibiotic treatments that kill Mtb and drug-resistant Mtb more effectively via new mechanisms of action are necessary. Discovering these antibiotics expediently requires that innovative Mtb-specific drug-screening assays are developed. An ideal and innovative TB drug screening method would target validated protein-protein interactions (PPI) essential to Mtb's pathogenesis and would be performed on whole Mtb cells under relevant in vivo-like conditions. This project focused on engineering several tools relevant to creating an ideal TB drug screen. A protein fragment complementation assay capable of studying PPI of the TB gyrase complex was created, and this assay was assessed for future HTS applications. To streamline the readout, this assay was re-engineered to include green fluorescent protein.

No description available.