A sense of place is important to the construction, believability and success of regional mystery novels. Authentic representation of place is challenging if an author is not originally from the area being portrayed. Despite this, some authors are able to depict foreign places more comprehensively and realistically than others. Professor Gary Hausladen of the University of Nevada, Reno identifies: narrative description, dialogue, iconography, and attention to detail as the basic literary devices that convey sense of place. This thesis questions the manner in which successful mystery novelists writing about foreign places meet Hausladen's model. Specifically, do they use all four of the literary devices, which are most commonly used, which are consciously used, and what research methods and resources do they use to incorporate the literary devices. Primary and secondary data are collected through interviews and literary analyses. It is found that these authors use all four of the prescribed literary devices, that some of the literary devices are more challenging to use than others, that place establishing literary techniques are important to the authors and that the authors seek to incorporate sense of place through diverse types of intensive research.

Practitioners have proposed that Digital Natives prefer graphics while Digital Immigrants prefer text. While Instructional Design has been extensively studied and researched, the impact of the graphical emphasis in instructional designs as it relates to digital propensity has not been widely explored. Specifically, this study examined the performance of students when presented with text-only and graphic-only instructional formats. The purpose of this study was to test the relationship between Digital Propensity Index scores of individuals and their performance when interpreting online instruction. A sample of students from the population of a large metropolitan university received the Digital Propensity Index questionnaire, which is a measure of an individual's time spent interacting with digital media. Each student was randomly assigned varying formats of a computer-based instructional unit via a public survey. The instructional unit consisted of the DPI questionnaire and six tasks related to the Central Florida commuter rail system. Participants were asked to answer the DPI questionnaire on a website by clicking on a link in an emailed invitation. Following the DPI questionnaire, participants were randomly assigned to one of two groups. Group One saw three instructional tasks shown in text and shuffled in random order. Each task was displayed on its own webpage. By submitting an answer to the task, the group progressed through the website to the next task. Group Two saw graphic tasks first, again, shuffled in random order. After the first three tasks, the groups swapped instructional formats to view the opposing group's initial questions. Participants were timed on how many seconds they spent reviewing each task. Each task had an assessment question to evaluate the learning outcomes of the instructional unit. Finally, the DPI score of the participant was matched with the time spent viewing each presentation format. The findings indicate that DPI score had a statistically significant prediction of time spent navigating each type of instruction. Though the link between DPI score and time spent navigating instruction was statistically significant, the actual measurable time difference between navigating text and graphic formats was only a fraction of a second for each increment in DPI score. Limitations and potential future research related to the study are discussed as well.

Snyder-Robinson syndrome (SRS) is an X-linked neurodegenerative disorder affecting males. The disease appears early in childhood with symptoms like bone abnormalities, reduced muscle mass, and mobility issues. It results from disrupted polyamine biosynthesis, which is due to a mutation in spermine synthase (Sms). This causes an abnormally elevated Spermidine: Spermine ratios. There is no approved SRS treatment, rather only management of symptoms. A genetic mouse model for the SmsG56S mutation found in some SRS patients was characterized, and a novel spermine Prodrug treatment was tested. The hypothesis is that male SmsG56S mutant mice exhibit polyamine dysregulation and SRS traits, while Prodrug intervention may rebalance abnormal ratios and facilitate a normalized phenotype. Mice were phenotyped in pure C57BL/6J, mixed C3H, and backcrossed C57BL/6J x C3H backgrounds. Lethality of the mutation, especially in C57BL/6J mice, was an obstacle. Viable mutant mice exhibited reduced body weight, typically smaller size, and lower bone densities compared to age-matched wild-type mice. Prodrug treatment was performed using different dosing strategies and in all backgrounds. Upon histological examination, testes and bone exhibited subtle defects in affected mutant male mice, while no detectable differences were found in skeletal muscle, liver, or kidney compared to wild-type mice. Acute prodrug treatment using oral gavage 5 times per week over 2 weeks was found to rebalance the Spermidine: Spermine ratio. Repeated efforts to dose Prodrug over a longer 6-8 week duration in mice required lower intraperitoneal doses but outcomes may have been moderated by the mice background. Overall, the SmsG56S phenotype in the testes and bone are consistent with other mutant Sms models, although C57BL/6J mice seemed to be more sensitive to the SmsG56S mutation. Further testing of Prodrug is needed, including in younger mice and for a longer duration of treatment, to evaluate Prodrug effectiveness in improving traits in SmsG56S mice.

No description available.

<p>This thesis explores the intersection of storytelling and spirituality in contemporary Native literature in Canada. The invocation of the oral tradition and its history will be examined in the works of Eden Robinson, Joseph Boyden, and Harry Robinson, as each author attempts to orient his or her narratives within a First Nations framework. By gesturing towards orality in their written literature, these authors acknowledge the dialogic nature of a narrative that has been shaped by ancestral experiences and memory and thus write against the colonial master narrative of the contemporary Canadian nation-state. In Joseph Boyden's <em>Through Black Spruce</em>, Eden Robinson's <em>Monkey Beach</em>, and the transcribed collections of Harry Robinson's stories, the invocation of orality becomes the vehicle through which to explore Indigenous ways of knowing and traditional spiritual beliefs. This thesis first considers the ways in which the mode of storytelling allows each author to create a new narrative that introduces readers to an Indigenous perspective on the processes of history. It then examines the evolution of specific spiritual beings from traditional narratives into contemporary settings as a way to explore neocolonial attitudes and the compromised contexts of modern Indigenous life in communities across Canada that continue to be haunted by a legacy of colonialism. I end with an exploration of the potential for healing that each author envisions as communities move into a decolonization process through the regeneration of tribal languages, a reconnection to sacred space, and a reimagining of the Canadian master narrative and its colonial interpretation of history.</p> / Master of English

<p>Much of the critical discourse on J.M. Coetzee’s <em>Foe</em> does not fully investigate its relationship with Daniel Defoe’s texts, despite <em>Foe</em>’s intimate relation with them. This thesis offers a postcolonial reading of Coetzee’s Susan Barton, Cruso and Friday against Daniel Defoe’s original characters Roxana, Robinson Crusoe and Friday. Chapter one discusses Roxana-as-feminist, female colonizer, representative of her sex and Amazon and compares her to Barton. It reveals the tendency of critical discourse to attempt to ‘know’ Barton as they ‘know’ Roxana, by categorizing her, and reveals how Coetzee’s character frustrates attempts to define her. The second chapter addresses eighteenth-century knowledge of race and how it differs from present day, which offers an alternate reading of <em>Robinson Crusoe</em> and complicates its use as a colonial handbook. I also discuss masculinity in Defoe’s <em>Robinson Crusoe</em> as an individual characteristic Coetzee alters into something that can be appropriated. His characters are not masculine but can wield phallic symbols such as the pen and the knife to reveal power as systemic rather than individualistic. The final chapter offers an in depth postcolonial reading of Friday and interrogates critical discourse’s tendency to read him as representative of ‘the colonized,’ or as a colonial trope.</p> / Master of Arts (MA)

In this paper, I explore the environmental philosophy of three Californian modernists, who I have collectively named the Dust Dwellers: John Steinbeck, Robinson Jeffers, and Jack London. I argue that these writers participated in a broader modernist response to the ascendancy of the Enlightenment and its manifestation in industrial progress. Furthermore, I demonstrate that the Dust Dwellers' response was distinctly informed by their American identity. They engaged modernist themes of decay as applied to Western expansion and the dissolution of the American Edenic dream. Investigating the fractured relationship between civilization and the environment, they searched for a philosophy that could reconcile humanity to nature. Specifically, I argue that their environmental philosophy displays intellectual and creative congruencies that can be traced to the common influence of twentieth-century psychoanalyst Carl Jung. The foundational tenet of the Dust Dwellers' environmental philosophy parallels Jung's concept of the unus mundus. Mirroring Jung's interpretation of this alchemic term, the Dust Dwellers describe a cosmic unity that encompasses all of life. I discuss depictions of the unus mundus across the Dust Dwellers' work and outline other implications of this central philosophic presupposition. Ultimately, I conclude that their environmental philosophy, along with other attributes, permits and even encourages scholars to approach these writers as a distinct group of American modernists. / Master of Arts / In this paper, I explore the environmental philosophy of three Californian modernists, who I have collectively named the Dust Dwellers: John Steinbeck, Robinson Jeffers, and Jack London. I argue that these writers participated in a broader modernist response to the Enlightenment's failed pursuit of utopia. Furthermore, I demonstrate that the Dust Dwellers' response was distinctly informed by their American identity. They engaged modernist themes of decay as applied to the American frontier. Specifically, they recognized that America had failed to transform into a new Garden of Eden. Investigating the negative effects of industrial civilization, the Dust Dwellers searched for a philosophy that could create harmony between humanity and nature. I argue that their environmental philosophy displays intellectual and creative congruencies that can be traced to the common influence of twentieth-century psychoanalyst Carl Jung. The foundational concept of the Dust Dwellers' environmental philosophy parallels the Jungian concept of the unus mundus. Mirroring Jung's interpretation of this alchemic term, the Dust Dwellers describe a cosmic unity that encompasses all of life. I discuss depictions of the unus mundus across the Dust Dwellers' work and outline other implications of this central philosophic presupposition. Ultimately, I conclude that their environmental philosophy, along with other attributes, permits and even encourages scholars to approach these writers as a distinct group of American modernists.

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In the present work, we study some aspects of Einstein's theory of gravitation in general spacetimes with an arbitrary number of dimensions. In the first chapter we summarize the foundations of used geometric formalism and we derive the equation of goedesic deviation representing the relation between relative acceleration and the Riemann tensor. Second chapter presents different types of algebraic classification of the Weyl tensor in four and higher dimensions. Third chapter is devoted to a detailed examination of the test particle motions and also to the interpretation of different terms in the general equation of geodesic deviation. The fourth section examines appropriate choice of the interpretation frame and the coordinates. The final fifth chapter contains an analysis of the motion of test particles in the Robinson-Trautman spacetime with an arbitrary higher number of dimensions.

A colisão de buracos negros é uma das fontes mais importantes de ondas gravitacionais e, em geral, a emissão anisotrópica da radiação causa um recuo do objeto final. Este cenário já é conhecido há décadas, mas foi somente com o recente avanço na relatividade numérica que as velocidades finais dos objetos radiantes foram computadas com precisão. Os valores encontrados podem ser altos o suficiente para exercerem um importante papel no crescimento de buracos negros super massivos via coleção de galáxias e na abundância de núcleos galáticos ativos contendo buracos negros. Este é um autêntico efeito da não linearidade de Relatividade Geral e esta tese fornece uma nova metodologia estudar alguns aspectos da dinâmica da colisão de buracos negros. Consideramos o horizonte como uma tela canônica que codifica as informações da evolução temporal do espaço-tempo. Com esta hipótese, fenômenos como o anti-kick, isto é, uma súbita desaceleração do sistema antes de atingir a velocidade final, são explicado em termos da dissipação das deformações do horizonte. Estudamos primeiramente o Espaço-tempo de Robinson-Trautman. Uma das solução mais simples das equações de Einstein, esta métrica nos fornece um poderoso modelo para investigar tanto a perda de massa quanto o recuo do objeto final. Mostramos que, quando as configurações iniciais tem simetria especular, a massa do buraco negro remanescente e a energia irradiada são completamente determinadas pela condição inicial. Com isso, obtemos as expressões analíticas dos resultados numéricos obtidos anteriormente na literatura. Além disto, com o auxilio do método espectral de Galerkin, analisamos o regime não linear das equações envolvidas e verificamos que se pode estimar a velocidade de recuo final com boa precisão a partir de medidas da assimetria da condição inicial. Introduzimos na seqüência a curvatura efetiva como uma medida das deformações intrínsecas ao horizonte. Além de considerar as deformações gerais, ela também inclui as diferenças entre os hemisférios norte e sul. No espaço-tempo de Robinson-Trautman, essa quantidade se correlaciona de uma forma injetora com a velocidade final. Para superar algumas limitações dessa solução, aplicamos o mesmo procedimento nos resultados da simulação numérica de uma colisão head-on. Neste caso, a curvatura efetiva, está na realidade, correlacionada com a aceleração do sistema. Refinamentos e generalizações desta técnica são também discutidos e propostos para trabalhos futuros. / Colliding black holes are one of the most important sources of gravitational waves and the anisotropic emission of the radiation generally causes the recoil of the final hole. This scenario has been known for decades, but it is only thanks to the recent progress in numerical relativity that the final velocity have been accurately computed. The values found can be large enough to play an important role in the growth of supermassive black holes via mergers of galaxies and on the number of galaxies containing them. This is a genuine nonlinear effect of general relativity and this thesis provides a new methodology to study some features on the dynamics of the collision. We propose that the horizon is a canonical screen, which encodes he information of its surroundings. With this assumption, phenomena such as the anti-kick, namely the sudden deceleration before reaching the final velocity, are explained in terms of the dissipation of the horizons deformation. We first study the Robinson-Trautman spacetime. One of the simplest solutions of Einsteins equations, it provides us with a powerful toymodel to investigate both the mass loss of the system and the recoil of the final object. We show that, for the case of reflectionsymmetric initial configurations, the mass of the remnant black-hole and the total energy radiated away are completely determined by the initial data, allowing us to obtain analytical expressions for some numerical results that had appeared in the literature. Moreover, by using the Galerkin spectral method to analyze the non-linear regime of the equations involved, we found that the recoil velocity can be estimated with good accuracy from some symmetry measures of the initial data. Then we introduce the effective urvature as a measure of intrinsic deformations on the horizon. Not only does it account for overall deformation, but also for the differences on the north and south hemispheres. In the Robinson-Trautman spacetime, this quantity correlates in an injective way with the final velocity. To overcome some caveats of this solutions, we apply the same procedure to the results given by numerical simulations of a head-on collision. In the case, the effective curvature is actually correlated with the acceleration of the system. Further improvement and generalizations of this technic is also discussed and proposed for future work.