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Characterization and Comparison of Three Unique RNA Thermometers from Shigella dysenteriaeAlsip, Anna Kellen 16 September 2022 (has links)
No description available.
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Shut up and simplify : the writing process of Shut up and singBellina, John Gregory 10 December 2013 (has links)
This report documents the initial inspiration, development, and rewrites that went into the creation of John Gregory Bellina’s screenplay Shut Up and Sing. Furthermore, the following pages trace the evolution of the author’s writing during the entirety of his program experience. / text
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Hydrolyzed Polyacrylamide- Polyethylenimine- Dextran Sulfate Polymer Gel System as a Water Shut-Off Agent in Unconventional Gas ReservoirsJayakumar, Swathika 1986- 02 October 2013 (has links)
Technologies such as horizontal wells and multi-stage hydraulic fracturing have made ultra-low permeability shale and tight gas reservoirs productive but the industry is still on the learning curve when it comes to addressing various production issues. Some of the problems encountered while hydraulically fracturing these reservoirs are the absence of frac barriers, thinner shales and the increased presence of geological hazards. Induced vertical fractures sometimes extend to an underlying aquifer and become a conduit to the well. We have developed a low-concentration, low-viscosity and delayed-crosslink polymeric gel system as a water shutoff agent for hydraulically-fractured tight gas and shale reservoirs, where some fractures might connect to water rich zones. The system also is a significant improvement over traditional flowing gels for fracture water shutoff in conventional reservoirs because of these features. The gel uses high molecular weight hydrolyzed polyacrylamide (HPAM) at low polymer concentrations with a delayed organic crosslinker. This crosslinker is more environmentally benign and provides much longer gelation time and stronger final gels than comparable polymer loadings with chromium carboxylate crosslinkers at higher temperatures. The low viscosity system allows low-pressure extrusion of gelant into the narrow-aperture fractures present in unconventional gas reservoirs. The gelant can be pumped at low pressures due to lower polymer concentrations and delayed gelation point. This allows the potential to seal problem zones that are producing excess water even when the fractures conducting water have very narrow apertures. By impeding water production, the gel system developed here can effectively delay water loading thereby avoiding abandonment or installation of expensive equipment with increased operational costs, thus extending life and reserves of unconventional gas wells.
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Numerical simulation and interpretation of borehole fluid-production measurementsFrooqnia, Amir 18 September 2014 (has links)
Downhole production measurements are periodically acquired in hydrocarbon reservoirs to monitor and diagnose fluid movement in the borehole and the near-borehole region. However, because of the complexity involved with physical modeling and numerical implementation of borehole and formation multiphase flow behavior, inference of near-borehole petrophysical properties from production measurements is limited to simplified single-phase reservoir models. This dissertation develops a new transient coupled borehole-formation fluid flow algorithm to numerically simulate two-phase production logs (PL) acquired across heterogeneous rock formations penetrated by vertical and deviated boreholes. Subsequently, the coupled flow algorithm is used to estimate relevant dynamic petrophysical properties from borehole production measurements. The developed reservoir-borehole fluid flow model is based on an isothermal, one-dimensional (borehole axis) version of two-fluid formulation that simulates simultaneous flow of two fluid phases in oil-water, oil-gas, and gas-water flowing systems. Linkage of borehole and formation fluid flow models is carried out by introducing additional source terms into borehole mass conservation equations. Transient simulation of two-phase production measurements indicates the presence of borehole cross-flow when performing a shut-in test across differentially-depleted multilayer reservoirs. In a two-layer synthetic reservoir model penetrated by a vertical borehole, only two hours of through-the-borehole cross-communication of differentially-depleted layers gives rise to more than 14% increase in volume-averaged oil-phase relative permeability of the low-pressure layer. Simulated borehole fluid properties in the presence of cross-flow are used to estimate formation average pressure from two-phase selective-inflow-performance analysis. A new inversion-based interpretation algorithm is developed to estimate near-borehole absolute permeability and fluid-phase saturation from two-phase production logs. The inversion algorithm integrates production logs acquired in time-lapse mode to construct a near-borehole reservoir model that describes depth variations of skin factor over the elapsed time. Feasibility studies using synthetic reservoir models show that the estimated petrophysical properties are adversely influenced by the large volume of investigation associated with PL measurements. Moreover, undetectable fluid production across low-permeability layers decreases the sensitivity of production logs to layer incremental flow rate, thus increasing estimation uncertainty. Despite these limitations, the estimated fluid saturation and permeability across high-permeability layers are within 25% and 20% of the corresponding actual values, respectively. Oil-water and oil-gas flowing systems are additionally studied to quantify the added value of remedial workover operations (e.g., water and gas shut-off). Simulation of a gas shut-off performed in a gas-oil field example recommends a minimum bottom-hole pressure to prevent high gas production caused by (i) gas coning effects, and (ii) released gas from oil solution. Maintaining bottom-hole pressure above that limit gives rise to more than 60% reduction of downhole gas production. / text
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Pressure transients in wellbores : water hammer effects and implications for fracture diagnosticsMondal, Somnath 17 February 2011 (has links)
A pressure transient is generated when a sudden change in injection rate occurs due to a valve closure or injector shutdown. This pressure transient, referred to as a water hammer, travels down the wellbore, is reflected back and induces a series of pressure pulses on the sand face. This study presents a semi-analytical model to simulate the magnitude, frequency and duration of water hammer in wellbores. An impedance model has been suggested that can describe the interface, between the wellbore and the formation. Pressure transients measured in five wells in an offshore field are history matched to validate the model. It is shown that the amplitude of the pressure waves may be up to an order of magnitude smaller at the sand face when compared with surface measurements. Finally, a model has been proposed to estimate fracture dimensions from water hammer data. / text
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Oz Wide Shut: An Exploration of Gender and Master Narratives in Stanley Kubrick’s Final FilmCaplinger, James C. January 2004 (has links)
No description available.
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The Forgotten Gothic of Christina RossettiWallner, Lars January 2010 (has links)
In this essay, the author analyzes the Gothic of Christina Rossetti in such poems as A Coast Nightmare, Shut Out, but also the well-known Goblin Market and the Prince's Progress. Interested in what the imagery of these poems convey, and intent on declaring Rossetti as a prominent example of Gothic poets, the author makes a strong case for the including of Rossetti among the great Gothics.
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Att adaptera svartsjuka : En komparativ analys av hur subtext påverkats i adaptionen av romanen Dream Story till filmen Eyes Wide ShutRadhi, Yasser January 2016 (has links)
Subtext är en sanning gömd under ytan, som avslöjar en handling eller ords sanna mening. Hur kan en adaptionsprocess påverka subtexten då en bok tolkas om till film? Syftet med denna uppsats är att applicera en komparativ adaptionsanalys för att svara på frågan kring hur subtexten i en bok påverkas av att adapteras till film. Två kapitel och dess respektive filmscener analyseras därmed för att därefter peka ut dess subtext, detta från boken Dream Story och dess filmatisering Eyes Wide Shut. Skillnaderna i hur subtexten förmedlats pekas sedan ut i resultatet, där slutsatser kring adaptionsprocessen av subtext görs. Subtexten analyseras med hjälp av Linda Segers bok Writing Subtext: What Lies Beneath, vilket understöds med Thomas Denks teorier kring komparativa analyser i Komparativ metod – förståelse genom jämförelse. Resultatet har då pekat på att subtexten påverkats av att gå från en litterär till visuell tolkning, där mediespecifika detaljer påverkat berättandet. Dock har samma subtext i stor grad framförts i filmen, det har endast handlat om mediespecifika tolkningar.
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Étude des dégradations dans les piles à combustible PEMFC pendant les phases de démarrage/arrêt / Study of the degradations induced by start-up/shut-down operations in PEMFCLamibrac, Adrien 28 June 2013 (has links)
Cette thèse contribue à l'identification des mécanismes de dégradation qui ont lieu durant les phases de démarrage et d'arrêt des Piles à Combustible à Membrane Échangeuse de Proton. Dans un premier temps, des démarrages et arrêts individuels sont étudiés au moyen d'une cellule équipée de collecteurs de courants segmentés. Les courants internes qui sont produits durant ces opérations peuvent ainsi être mesurés. La mesure du dioxide de carbone dans les gaz d'échappement de la cathode révèle qu'une partie des courants internes correspond à de l'oxydation du carbone. Une autre part provient des réactions (réversibles ou non) d'oxydoréduction impliquant du platine. L'hétérogénéité des dégradations subies par la pile entre l'entrée et la sortie de la cathode est mise en évidence lors de protocoles de vieillissement répétant des démarrages et arrêts. Des analyses post-mortem révèlent un autre niveau d'hétérogénéité, qui concerne également le carbone, entre les dents et les canaux. De ces expériences, il ressort également que les dégradations sont plus importantes lorsque les gaz sont injectés à faible vitesse dans le compartiment anodique mais aussi quand de l'air est utilisé à la place de l'azote pour arrêter la pile. L'influence des caractéristiques de la MEA sur l'intensité des dégradations est aussi étudié. Un chargement en platine élevé à l'anode ou des électrodes avec des surfaces de carbone actif élevées accélèrent la chute des performances électriques. Au contraire accroitre le chargement en platine à la cathode limite ces pertes. Enfin, des simulations numériques des phases de démarrage complètent les résultats expérimentaux. L'oxydation réversible du platine est notamment identifiée comme étant responsable d'une part importante des courants internes / This works contributes to the identification of the various degradation mechanisms in Polymer Electrolyte Membrane Fuel Cell during start-up and shut-down operations. Single start-ups and shut-downs are first analysed using a cell with segmented cathode current collectors. Thus, internal currents which occur during these operations can be measured. Carbon dioxide measured in the cathode exhaust gas reveals that they result partially from carbon oxidation. Another contribution is the reversible or non reversible redox reactions involving platinum. The heterogeneity of the non reversible platinum oxidation between the inlet and outlet of the cathode is evidenced by the in-situ monitoring of the Electrochemical Surface Area during long-term start-up and shut-down aging protocols. Post-mortem analysis reveals another level of heterogeneity, which concerns also carbon oxidation, between land and channel. From these experiments, it appears also that degradations are more important when gases are injected with a low velocity in the anode compartment and when air is used instead of nitrogen to flush the anode compartment during shut-down. The influence of the MEA characteristics on the extent of the degradation observed during these aging protocols is also analyzed. High platinum loading in the anode and high surface carbon electrodes accelerate the drop of the electrical performances, while increasing the cathode platinum loading limits their decay. Finally, numerical simulations of start-ups complete the experimental results. Reversible platinum oxidation was found to be one of the main contribution to the internal currents
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EYS is a major gene involved in retinitis pigmentosa in Japan: Genetic landscapes revealed by stepwise genetic screening. / EYSは日本における網膜色素変性の主たる原因遺伝子である:多段階的な遺伝子スクリーニングにより明らかとなった日本人網膜色素変性患者の遺伝的背景Numa, Shogo 23 March 2021 (has links)
京都大学 / 新制・課程博士 / 博士(医学) / 甲第23098号 / 医博第4725号 / 新制||医||1050(附属図書館) / 京都大学大学院医学研究科医学専攻 / (主査)教授 小杉 眞司, 教授 滝田 順子, 教授 小川 誠司 / 学位規則第4条第1項該当 / Doctor of Medical Science / Kyoto University / DFAM
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