L'objectif principal de ce travail était l'étude et l'optimisation du procédé de lyophilisation en milieu aqueux et organique de l'ibuprofène. Une étude comparative approfondie a été réalisée à différents stades de la fabrication de l'ibuprofène lyophilisé pour les deux formulations étudiées. Cette étude comparative a été menée sur l'étape de formulation, sur le procédé de lyophilisation (congélation, sublimation, désorption) et sur les propriétés finales du produit (humidité, réhydratabilité, aspect...). On a observé, que l'utilisation comme solvant du mélange eutectique A, correspondant à une composition de 20% en TBA + 80% en eau (% massique), permettait une forte augmentation de la solubilité de l'ibuprofène et conduisait pour les mêmes conditions opératoires (Tshelf et Pc), à une augmentation des cinétiques de séchage d'un facteur 1,8, par rapport aux résultats observés avec la formulation d'ibuprofène à base aqueuse. Par ailleurs, la détermination expérimentale des valeurs des pressions de vapeur à l'équilibre solide-vapeur et de l'enthalpie de sublimation a été effectuée par deux méthodes différentes : la méthode thermogravimétrique et la méthode statique. Ces déterminations nous ont permis de conclure que l'augmentation des cinétiques de sublimation résultait essentiellement des valeurs plus élevées de la pression de vapeur à l'équilibre solide-vapeur et d'une valeur plus faible de l'enthalpie de sublimation de l'eutectique A par rapport à la glace. Ces données thermodynamiques ont aussi été utilisées comme paramètres clefs pour la modélisation de l'étape de sublimation sous Comsol Multiphysics. In fine, l'optimisation des paramètres opératoires de l'étape de sublimation par la méthodologie du Design Space a conduit à un lyophilisat final d'ibuprofène formulé à base organique qui satisfait entièrement aux critères standard de qualités recherchés (couleur, aspect, résidus de solvants etc). Un développement industriel de la formulation à base de co-solvant organique apparait plus avantageux qu'avec la formulation à base aqueuse.

Title from PDF of title page. / Document formatted into pages; contains 70 pages. / Thesis (M.S.E.E.)--University of South Florida, 2003. / Includes bibliographical references. / Text (Electronic thesis) in PDF format. / ABSTRACT: Currently thin film solar cells have efficiencies in the range of 16-18%. Higher efficiencies of 20% or more can be achieved by two junction solar cells in which two p-n junctions are connected in series one on top of the other in a tandem structure. The ideal bandgaps for optimum efficiency in a tandem structure are about 1eV for the top cell and 1.7 eV for the bottom cell. Copper Indium Gallium di-Selenide (CIGS) with a bandgap of 1 eV is a suitable candidate for the bottom cell and Cadmium Zinc Telluride (CZT) with a tunable bandgap of 1.44-2.26 eV is a suitable candidate for the top cell. This work involves characterization of cadmium zinc telluride films and solar cells prepared by close spaced sublimation. CZT is deposited by co-sublimation of CdTe and ZnTe. The process has been investigated on various wide bandgap semiconductor materials including cadmium sulphide, cadmium oxide and zinc selenide. / ABSTRACT: Different post deposition heat treatments were carried out to determine their effect on film and device properties. Characterization of the CZT devices was done using XRD, EDS, SIMS, J-V and spectral response measurements. CZT (Eg 1.7 eV) /CdS exhibited best performance when compared to the other window layers investigated. The best device exhibited Voc=640mV, FF=40% and Jsc=4.5 mA/cm2. The theoretical performance of CZT based solar cells were investigated using SCAPS. The effect of bulk and interface defects on the device parameters were studied. / System requirements: World Wide Web browser and PDF reader. / Mode of access: World Wide Web.

Thesis (Ph. D.)--University of Massachusetts Amherst, 2009. / Open access. Includes bibliographical references (p. 187-214). Print copy also available.

L'enjeu principal de cette recherche est de questionner ce que l'analyse psychodynamique du travail peut apporter à l'anthropologie psychanalytique du sens moral. Une explicitation des références doctrinales est un préalable nécessaire pour discuter la façon dont la psychanalyse et la psychodynamique du travail conçoivent les réquisits du sens moral. La démarche clinique et critique adoptée au cours de cette thèse tend conjointement à décrire et comprendre l'expérience vécue des sujets rencontrés, et à discuter les constructions métapsychologiques censées rendre compte de cette même expérience. Selon notre point de vue, la psychodynamique du travail apporte des éléments de discussion essentiels, et pourtant insuffisamment pris en compte par la psychanalyse, pour élucider les conditions de construction et de suspension du sens moral. Nous développerons l'idée qu'en sus d'une théorie du corps affecté dans le rapport au réel, une anthropologie du sens moral ne peut se passer d'une théorie du travail.

My concern in Dead Drunk is not simply the subject matter of death, it is rather with the representation of drunks in the form of fictional phantoms in The Glass Canoe and Bliss as rendering the death drive visible. Close scrutiny of the representation of the drunk in Australian fiction, as discussed in relation to The Glass Canoe, and Bliss reveals a ‘constant recurrence of the same thing’ rendered uncannily visible. On inspection, what becomes visible is recurring deaths and subsequent resurrections. For the ghostly Australian drunk there is always the possibility of resurrection, but that resurrection is usually in the form of another drink. A drink promises resurrection, but instead delivers a return or recurrence of the drunken, ghostly state. / The presence of drinking and drunks in Australian fiction can be described as a haunting, the ghostly drunks as repetition of an anachronistic past. It is the repetition of the representations of drunks as ghostly presences in Australian fiction that is telling. Utilising Sigmund Freud’s theories developed in ‘The Uncanny’ (1919) and Beyond the Pleasure Principle (1920), I propose that if the uncanny is an encounter with one’s origins and the death drive is a backward looking return to origins; the drunks are a past that is repeatedly encountered in an uncanny moment. Utilising the modalities of the uncanny in regards to The Glass Canoe reveals the guises of the drunken ghosts. Making reference to an Australian colonial past, founded on intoxicant use and abuse the dissertation suggests alcoholism as a white man’s dreaming. A discussion of Bliss links the uncanny ghosts to a registration or surfacing of the death drive. In conclusion I suggest the psychoanalytic concept of sublimation as both an explanation for and a release from the symptomatic repetition. / Floundering, the creative work, is an extract from a novel in progress. The section presented is the opening to the novel. The narrative unfolds during one day, New Year’s Eve, and involves the interactions between the two brothers Jordy and Tom, and Old Fat. Loretta, the boys’ absent mother, haunts the novel and drives the narrative. Although the creative work does not explicitly depict dead drunks as discussed in the dissertation, the theory has by necessity permeated the creative, and the creative permeated the theory, forming a chiasma – a crossing over between strands of thought.

Thesis (MA)(CrWrtg) --University of Melbourne, Dept. of Media and Communications, Faculty of Arts, 2009. / Typescript. Includes bibliographical references (leaves 36-40)

Techn. Universiẗat, Diss., 2004--Darmstadt.

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior / De Assinalações a DESTERRO: investigações entre arte e subjetividade é uma reflexão sobre o processo de construção das obras das séries SORTERRO e DESTERRO. Tais trabalhos se utilizam de pelos e cabelos como matéria física e conceitual na sua elaboração e a partir destes elementos dar-se inicio a uma série de investigações que buscam trazer a tona os meandros do processo da criação e produção artística. A investigação inicia com a visita a algumas obras anteriores em que o elemento cabelo aparece. A partir daí uma serie de temas atravessam o caminho. Dentre os quais estão as questões relativas ao corpo, à vida e à morte, ao desejo, ao trauma, à biografia, ao acaso, ao medo, ao erotismo, à animalidade, à perversão, a sublimação e à linguagem. Dentre os autores mais visitados estão: Georges Bataille, Jacques Derrida e Gilles Deleuze / From Assinalations to Exile: Investigations between Art and Subjectivity is a reflection about the building process of the artworks from the series SORTERRO and EXILE. These artworks used fur and hair as physical and conceptual matter, and, after these elements, started a process of investigations that would seek to bring to light the intricacies of the creation process. The has investigation initiated with the contact with some previous artworks that the element hair could have been found. After that, a series of themes crossed the pathway taken. Among them, issues related to body, to life and death, to desires, to trauma, to biography, to fortuity, to fear, to eroticism, to animalism, to perversion, to sublimation and to the language appeared. Among the most visited authors, there are: Georges Bataille, Jacques Derrida and Gilles Deleuze

Este trabalho apresenta os resultados da pesquisa Corpo Docente Corpo Doente: Por Que Padece o Corpo? O principal objetivo era investigar a possibilidade de o Mal-Estar Docente constituir a profissão do magistério, assim como o mal-estar caracteriza e constitui o progresso da humanidade, Freud (1998). A questão central da pesquisa era descobrir se assim como o Mal-Estar na Civilização, o Mal-Estar Docente também derivaria de situações presentes na configuração atual do magistério. Portanto, discorre sobre algumas formas de mal-estar que marcaram o desenvolvimento da civilização, agrupadas em cinco modalidades. O trabalho adota o estudo de cunho reflexivo e almeja contribuir com o debate teórico para uma abordagem alternativa do Mal-Estar Docente. Agrega aos estudos as reflexões provenientes das entrevistas realizadas com médicos que atuam na Coordenadoria de Valorização do Servidor, da Prefeitura Municipal do Rio de Janeiro. Destaca-se o posicionamento da pesquisa em relação ao Mal-Estar Docente pelo viés da subjetividade do professor. O trabalho considera importantes as pesquisas que apresentam o mal-estar do ponto de vista social, mas discorda da ênfase dada exclusivamente aos fatores sociais. Freud (1998), Zaragoza (1999), Codo & Menezes (2000), Adorno (2003), Rouanet (2003) e Birman (2007) foram os referenciais teóricos utilizados. A partir do diálogo entre os autores e da análise das entrevistas, constatou-se que algumas situações presentes na configuração do magistério realmente contribuem para o problema do Mal-Estar Docente. A pesquisa revelou, ainda, o imperativo de novas investigações sobre a situação dos professores que buscaram estratégias de saúde para não cair no adoecimento, para inquirir os impactos do silenciamento da sexualidade docente sobre a prática do professor e para averiguar como a sublimação pode ser desenvolvida no espaço escolar.

This thesis explores Karl Barth’s (1886-1968) argument for “The True Religion” in his 'Church Dogmatics' I/2, §17.3, particularly the four “aspects” (i.e., creation, election, justification, and sanctification). Because this thesis focuses on Barth’s theology of the true religion and its four “aspects,” it contributes to a knowledge of his theology of religion in general and the Christian religion in particular by offering a more holistic interpretation of his theology of religion as both wholly negative and wholly positive in contrast to the vast majority of scholarship which interprets Barth’s theology as only against religion. By using the retranslation of §17 wherein the infamous German word Aufhebung is rendered more correctly as “sublimation” (rather than the original “abolition”) this thesis argues that Barth’s theology of religion is not wholly negative; rather, that of all religions God solely sublimates the Christian religion. This thesis focuses exclusively on Barth’s Church Dogmatics and in chapter one it provides a thorough exegesis of §17 to show how the four “aspects” in his theology of the true religion are the culmination of his argument that the Christian religion is the true religion. This is accomplished by emphasizing Barth’s use of the simul iustus et peccator, which is the analogous paradigm to understand the Christian religion as the true religion, because even though the Christian religion is wholly sinful it is also wholly just as evidenced in God’s sublimation of it. In chapters two through five each “aspect” is respectively exposited first and then proceeds to the corresponding sections in the later volumes of Barth’s Church Dogmatics that display the strongest theological continuity with each “aspect” in order to demonstrate how they complement, correct, and complete his theology of the true religion. The first “aspect” on creation sees Barth stress the anhypostasis of the humanity of Jesus Christ, which has continuity with his theology of the affirmation of creation in III/1, §42, especially creation as justification. In the second “aspect” on election Barth employs the covenant between Old Testament Israel and the Christian religion, which he also utilizes in II/2, §34, particularly in the twofold judgment and mercy of God. In the third “aspect” on justification Barth emphasizes the theme of the forgiveness of sins, which corresponds to IV/1, §61, specifically the pardon of the sinner. The fourth “aspect” on sanctification, particularly the motif of proclamation, aligns with his theology of sanctification in IV/2, §66, particularly the praise of the Christian’s works. This thesis concludes by offering an ethical postscript, which derives from and builds upon its discussion and enlargement of the four “aspects” and prescribes a posture of humility in which the Christian religion must relate towards other religions because it is also still a religion. This ethic also includes a purified pride in which the Christian religion boldly proclaims to all other religions that God sublimates it alone into the true religion in the hope that the adherents of other religions will eventually join the Christian religion.