In his most popular prose work, Mary Magdalens Funeral Teares (1591), English Jesuit Robert Southwell adapts the Mary Magdalene tradition by incorporating the meditative practices of St. Ignatius Loyola coupled with the Petrarchan language of poetry. Thus, he creates a prose work that ministered to Catholic souls, appealed to Protestant audiences, and initiated the literature of tears in England. Southwell readapts the traditional image of Mary Magdalene for a Catholic Early Modern audience by utilizing the techniques of Jesuit meditation, which later flourished in the weeper texts of Richard Crashaw and George Herbert. His vividly imagined scenes also employ the Petrarchan and Ovidian language of longing and absence and coincide with both traditional and mystic early church writers such as Bernard and Augustine. Through this combination, Southwell’s Marie Magdalens Funeral Teares resonated with Catholics deprived of both ministry and the presence of Christ in the Eucharist. These contributions solidify Southwell’s place as a pivotal figure in the religious and literary contexts of Early Modern England.

Cette recherche porte sur la genèse et l’évolution des Troubles Musculo-Squelettiques (TMS) dans un établissement de l’industrie aéronautique. Nous proposons une formalisation de nos résultats regardés par le prisme 1. des régulations construites par les compagnons, 2. des phénomènes d’usure, et 3. des processus de mise à l’abri des compagnons lourdement affectés par des douleurs articulaires.Pour ce faire, nous avons construit une approche compréhensive pluridisciplinaire associant des actions en entreprise (analyses ergonomiques de l’activité, entretiens diachroniques menés avec le médecin du travail du site, reconstitution de parcours professionnels de compagnons reclassés pour raisons de santé) et une approche statistique, par des exploitations de l’observatoire EVREST en œuvre dans le groupe industriel depuis le début des années 2000.Nos résultats proposent un regard sur la genèse des TMS, suggèrent des perspectives de prévention, encouragent à construire une mémoire de l’entreprise, et à analyser l’activité (au niveau micro des opérateurs, comme au niveau de l’entreprise) d’une manière indissociable des temps, entre passé, présent et avenir. / This research aims at studying the genesis and evolution of Musculo Skeletal Diseases (MSD) in a company belonging to the aeronautics sector. We put forward a formalization of our results, examined through the prism of 1. Regulations elaborated by the workers, 2. Wear and tear phenomena, and 3. Sheltering processes for workers suffering from serious joint diseases.We have therefore built a comprehensive multidisciplinary approach, associating studies at the workshop level (ergonomic job analyses, diachronic interview carried out with the participation of company’s job physician, reconstitution of professional courses of workers reallocated because of health disorders) and a statistical approach, using the “Evrest” Observatory, undertaken in this industrial group from 2000 on.Our results provide a view of the genesis of MSD, suggest avenues for prevention, encourage to build a memory inside the company, and to analyze activity (at the micro level of workstations, as well as at company level) without separating past, present, and future periods.

Made available in DSpace on 2016-06-02T19:52:02Z (GMT). No. of bitstreams: 1 5718.pdf: 19273613 bytes, checksum: 5513939eb0582427e140f188b3104e37 (MD5) Previous issue date: 2013-04-26 / This work aims to perform the analysis of complaints made by workers within the sugar cane cutting business and their correlation with clinical outlook during the emergency care in a public health unit and its relationship to work in the cane. The results found from the survey of the medical records, the laboratory tests, and the interviews with the workers, present the relationships between diagnoses and characteristics of the work process, in addition to determining the absence of care protocol directed to such worker, whom does not find in the public health system of which it is to him constitutionally guaranteed. The disorders related to the work/health relationship and the conditions found that it should allow for redemption of its homeostasis are presented here in order to provoke thought about this dissonance. / Esse trabalho tem como propósito a realização da análise das queixas apresentadas pelos trabalhadores do corte da cana-de-açúcar e suas correlações com o quadro clínico detectado no atendimento de emergência em unidade pública de saúde e sua relação com o trabalho na cana. Os resultados encontrados, a partir do levantamento dos prontuários médicos, da realização de exames laboratoriais e de entrevistas com os trabalhadores, mostram as relações entre os diagnósticos realizados e as características do processo de trabalho, além da determinante ausência de protocolo de atendimento direcionado a esse trabalhador, qual não encontra no serviço público de saúde a assistência que constitucionalmente lhe é garantida. Os distúrbios relacionados à relação trabalho/saúde e as condições encontradas que lhe deveriam permitir o resgate da sua homeostase são aqui apresentados de forma a provocar reflexão a respeito dessa dissonância.

Synthetische Hochleistungswerkstoffe, in Faserform, haben sich bisher in Gebieten wie dem Freizeitsport (Klettersport, Segelsport), Seetechnik (Ankerleinen, Zugleinen) und Schutzausrüstung (Ballistik, Arbeitsschutzbekleidung) bewehrt. Die Einführung von Hochleistungsfasern in weiteren Anwendungsfeldern wird durch Schwachstellen im Materialverhalten der Fasern selbst verhindert. So gilt unter Anwendern und Entwicklern das Problemfeld des inneren Verschleißes der textilen Halbzeuge bei Belastung auf Zug und Biegung, durch gegenseitiges Schädigen der Garne, als Haupthindernis zur weiteren Verbreitung von Textilstrukturen aus synthetischen Hochleistungspolymeren. Es kann davon ausgegangen werden, dass die Lebensdauer von z.B. Seilen und Bändern aus Hochleistungsfasern signifikant erhöht werden kann, falls es gelingt, bestimmte Schädigungsmechanismen wie Alterung durch Strahlung, aggressive Medieneinflüsse und inneren Verschleiß auszuschließen bzw. zu mindern. Da eine, wie auch immer geartete, nachträgliche Ausrüstung oder Modifizierung der Hochleistungsfasern durch den Weiterverarbeiter (z.B. Seilerei, Weberei, Konfektionär etc.) oder individuelle Bereitstellungen durch die Hersteller ausgeschlossen ist, werden für die Erarbeitung von Lösungsansätzen folgende Randbedingungen vorgeschlagen: die Modifikation des Endverbundes erfolgt nicht durch Veränderungen an der Hochleistungsfaser, sondern durch zusätzlich eingebrachte Hilfsfasern. Das Einbringen der Hilfsfasern soll mit in der Textiltechnik üblicher Weise vorhandener Maschinentechnik möglich sein. Die Ausrüstung der Hilfsfasern erfolgt vorrangig durch Additive, primär mittels Compoundierung im Schmelzspinnprozess. Die vorliegende Arbeit wird zunächst versuchen die Auswirkungen dynamischer Belastungsprozesse auf textile Zug- und Tragmittel aus Hochleistungsfasern zu erfassen. Nach Aufnahme des Schadbildes werden dann die ausgerüsteten Hilfsfasern charakterisiert, d.h. es werden solche mechanischen und physikalischen Parameter erfasst und deren Änderung beschrieben, welche in dem zu erwartenden tribologischen System aus Hochleistungsfaser und Hilfsfasern ausschlaggebend sind. / Advanced synthetic materials, in the shape of synthetic high-performance fibers, are well established in areas such as leisure sports (climbing, sailing), maritime technology (anchor lines, load lines) and reinforced protective equipment (ballistics, protective work clothing). The introduction of high-performance fibers in other fields of application is hindered by deficiencies in the material behavior of the fibers themselves. Whereas the problem of inner wear of the textile-semi-finished products, due to tension and bending loads, causes mutual harm to the fibers. This is considered being the main obstacle to the further spread of textile structures made of synthetic high-performance polymers among users and developers. It can be assumed that a significantly increase of lifetime, of e.g. fiber ropes and narrow fabrics, can be achieved if it succeeds, to exclude certain damage mechanisms such as aging resulting from radiation, aggressive media influences and inner wear. Since any subsequently equipment or modification of high-performance fibers by the manipulators (e.g. rope factory) or individual deployments by the manufacturer are excluded, the following general conditions are suggested for the development of approaches in this work. The modification of the final textile product is not been carried out due to changes on the high-performance fiber, but by additionally introduced assisting fibers. Introducing the assisting fibers to the textile product needs to be carried out on textile technology in common ways on existing machinery. The modification of the assisting fibers will be carried out, primarily through commercially available additives, during compounding in the melt spinning process. This paper will first attempt to capture the effect of dynamic load processes on textile-based tension and hoist members, made of high-performance fibers. After recording the damage structure, the equipped assisting fibers are characterized then. The investigations are including such mechanical and physical parameters, which are crucial in the expected tribological system of high-performance fiber and assisting fibers.

The effect of individual and combined zirconium and manganese additions have been compared for an AA2198 6 mm thick sheet in T351 temper regarding their influence primarily on recrystallisation resistance and secondly on fracture toughness and overageing resistance. A complete characterisation of the dispersoid distributions was carried out for a deeper understanding of the effects of the Al3Zr and Al20Cu2Mn3 particles, involving studying their formation from the as-cast and homogenised stage.The most important finding in this work was the lower recrystallisation resistance in the alloy containing 0.1 wt%Zr + 0.3 wt%Mn compared to that containing only 0.1 wt%Zr. This result was rather unexpected, if one considers the opposite microsegregation patterns of Zr and Mn during casting, which leads to dispersoids occupying the majority of the grains’ volume and minimising dispersoid-free zones that could be potential sites for nucleation of recrystallisation. The other two alloys with dispersoid additions 0.05 wt%Zr + 0.3 wt%Mn and 0.4 wt%Mn, were partially and fully recrystallised respectively in the rolled T351 condition.Equally important in this work, was the observation that the opposite microsegregation trend of Zr and Mn sufficed to restrict grain growth in unrecrystallised areas. The 0.1Zr-0.3Mn alloy exhibited the lowest grain size of all alloys, both in the T351 temper and after annealing at 535oC for up to 144 hours. The reason for this was the combined action of Al20Cu2Mn3 dispersoids and Mn solute in the regions where the Zr concentration was low (i.e. near the grain boundaries), which offered additional pinning pressure to those areas compared to the 0.1Zr alloy.The lower recrystallisation resistance of the 0.1Zr-0.3Mn alloy was explained on the grounds of two main factors. The first was the lower subgrain size and hence stored energy within bands of Al20Cu2Mn3 dispersoids, which increased the driving force for recrystallisation in these regions. The second was the interaction between Zr and Mn that led to a decrease in the Al3Zr number density and pinning pressure. Since Zr was the dominant dispersoid family in terms of inhibiting recrystallisation, inevitably this alloy became more prone to recrystallisation. The Al3Zr pinning pressure was found to be much lower especially within bands of Al20Cu2Mn3 dispersoids. The detrimental effect of the Mn addition on the Al3Zr distribution was proven not to result from the dissolution of Zr within Mn-containing phases, and several other phases, at the grain interior and also in grain boundaries. The observed effect could not be precisely explained at this stage.Concerning mechanical properties, the 0.1Zr alloy exhibited the best combination of properties in the Kahn tear tests for fracture toughness. Further, it had a higher overageing resistance compared to the 0.1Zr-0.3Mn alloy.As an overall conclusion from this work, considering all the studied properties here that are essential for damage tolerant applications, the addition of 0.1 wt%Zr to the AA2198 6 mm thick sheet was found to be superior to that of the combined addition of 0.1 wt%Zr + 0.3 wt%Mn.

L'objectif de ce travail était de rendre compte d'une revue complète de la littérature comparant les différentes méthodes et techniques de mesure de la pente tibiale par la radiographie conventionnelle, le scanner et l'IRM pour aider les chirurgiens orthopédistes à établir une méthode de mesure standardisée et fiable. Le travail inclut aussi deux études rétrospectives mesurant la pente tibiale en utilisant des modalités différentes. Il a été rapporté que la pente tibiale postérieure (PTS) a une influence sur la cinématique du genou notamment le ligament croisé antérieur (LCA). Une meilleure compréhension de la signification de la PTS pourrait améliorer le développement du dépistage des lésions du LCA, et les programmes de prévention, et pourrait servir de base pour des programmes de réadaptation individuels adaptés après la reconstruction du LCA. De plus, dans plusieurs interventions orthopédiques telle que l'ostéotomie tibiale haute, la pente tibiale peut modifier la mécanique du genou. Dès lors, une mesure préopératoire exacte de la pente tibiale postérieure est obligatoire. Plusieurs méthodes sont utilisées sur des radiographies conventionnelles, des scanners et l’IRM, mais jusqu'à présent il n'y a aucune méthode standard validée. La première partie de ce travail consiste en une introduction générale des structures anatomiques d'intérêt impliquées dans cette étude, à savoir l'articulation du genou, les ligaments croisés antérieurs, les ménisques et le tibia. Cette partie d'introduction inclut une description de l'anatomie brute, de la structure microscopique, de la fonction et quelques considérations cliniques. La deuxième partie du travail est consacrée à une revue systématique des modalités et techniques disponibles dans la littérature. Les informations quant aux méthodes de mesure de la pente tibiale chez des sujets normaux et avec LCA-lésé ont été extraites de toutes les études incluses de manière systématique, et ont été classifiées selon la technique de mesure et les modalités utilisées. L'axe le plus utilisé était l'axe tibial anatomique proximal (PTAA), et la méthode Midpoint est la plus fréquemment utilisée pour calculer le PTAA. Les valeurs les plus grandes de la pente tibiale médiale (MTS) et de la pente tibiale latérale (LTS) ont été obtenues en utilisant l'axe du cortex tibial antérieur, tandis que les valeurs les plus faibles ont été obtenues avec l'axe tibial diaphysaire. En comparaison directe, la plus grande valeur de la MTS pour le genou pathologique a été trouvée par les études radiologiques, tandis que les études IRM ont présenté les plus petites valeurs. Par conséquent, pour la LTS, les valeurs IRM étaient plus petites que celles des études par CT. La troisième partie du travail était une étude de cas-contrôle, en utilisant l'IRM; les LTS, MTS et pentes des ménisque interne et externe (LMS, MMS) ont été comparés chez 100 patients avec un LCA-déchiré isolé et chez un groupe témoin de 100 patients avec une douleur patello-fémorale et un LCA intact. La découverte la plus importante de cette étude consiste en ce que les pentes tibiales augmentées, aussi bien osseuse que méniscales, sont des facteurs de risque pour la blessure du LCA. Comme le ménisque a tendance à corriger la pente observée vers l'horizontale, la perte du ménisque postérieur peut potentialiser cet effet en augmentant la pente fonctionnelle. La quatrième partie du travail visait à évaluer les effets des caractéristiques des patients, du délai entre la blessure et l’intervention (TFI) et de la pente tibiale postérieure sur les formes de lésions des ménisques. Chez les 362 patients ayant un LCA-déchiré, le site de la lésion méniscale le plus commun était la corne postérieure (PH) du ménisque médial (MM), suivi par la lésion impliquant le MM entier. L'âge du patient, le BMI (Body Mass Index) et le TFI ont été significativement associés à l'incidence de la lésion du MM... [etc] / The aim of this work was to report a comprehensive literature review comparing the different methods and techniques of measurement of the posterior tibial slope (PTS) among the conventional radiograph, computed tomography (CT), and magnetic resonance imaging (MRI) in order to help the orthopedic surgeons to establish a standard and reliable measurement method. The work also includes two retrospective studies measuring the tibial slope using different modalities. It has been reported that the PTS has an influence on the kinematics of the knee notably the anterior cruciate ligament (ACL). A better understanding of the significance of the PTS could improve the development of ACL injury screening and prevention programmes, and might serve as a basis for individual adapted rehabilitation programmes after ACL reconstruction. Additionally, in several orthopedic interventions such as high tibial osteotomy, the tibial slope can result in altered knee mechanics. Therefore, an exact preoperative measurement of the posterior tibial slope is mandatory. Several methods are used on conventional radiographs, CT and MRI, but until now there is no standard validated method. The first part of this work was a general introduction about the anatomical structures of interest involved in this study, namely the knee joint, the anterior cruciate ligaments, the menisci, and the tibia, this introduction part included the gross anatomy, the microscopic structure, function, and some clinical considerations. The second part of the work is dedicated to a systematic review of the available modalities and techniques in the literature. Information regarding methods of measurement of the tibial slope in normal and ACL-injury subjects was extracted from all the studies in a systematic fashion and classified according to the measurement technique and used modalities. The most common used axis was the proximal tibial anatomical axis (PTAA), and the midpoint method is the most frequently used method for calculating the PTAA. By direct comparison, the greatest value of the medial tibial slope (MTS) for the pathological knee was achieved by the radiological studies, while the MRI studies presented the smallest values. Consequently, for the pathological lateral tibial slope (LTS), the MRI values were smaller than that of the CT studies. The greatest values of the MTS and LTS were obtained by the anterior tibial cortex axis, while the minimum values were achieved by the tibial diaphyseal axis.This third part of the work was a case-control study, by using MRI, the bony slopes as well as the lateral and medial meniscal slopes (LMS, MMS) were compared in 100 patients with isolated ACL injury and a control group of 100 patients with patello-femoral pain and an intact ACL. The most important finding of this study is that the increased tibial slopes, both bony and meniscal, are risk factors for ACL injury. As the meniscus tends to correct the observed slope towards the horizontal, loss of the posterior meniscus may potentiate this effect by increasing the functional slope. The fourth part of the work is aimed to evaluate the effects of the patient characteristics, time from injury (TFI), and PTS on meniscal tear patterns. In the 362 ACL-injured analyzed patients; the most common tear location was the posterior horn (PH) of the medial meniscus (MM), followed by tear involving the whole MM. Patient age, BMI, and TFI were significantly associated with the incidence of MM tear. An increase in the tibial slope, especially of the lateral plateau, seems to increase the risk of tear of the lateral meniscus (LM), and of both menisci

This work deals in the theoretical part in its theoretical part with a summary and detailed description of selected diagnostic methods that were applied to selected structural parts of an existing bridge structure within the practical part. The thesis also deals with the basic terminology and terminology in the field of bridge construction, subsequently, in its practical part deals in terms of diagnostics, the implementation of structural and static survey and subsequent evaluation of the current structural, technical and static state on selected structural units of existing reinforced concrete bridge structures

The diploma thesis deals with the construction and technical survey of a reinforced concrete structure. The theoretical part describes the tested properties of concrete and the methodology of their tests used in the practical part. The practical part is devoted to the diagnosis of the existing structure, which was determined the strength of concrete using core holes, concrete adhesion by tear tests, and reinforcement of reinforced concrete elements of the structure determined by ground-penetrating radar, electromagnetic indicators and additional chopped probes.

In this thesis, we start with the description of the biophysical properties of the plasma membrane models upon signaling processess such as the increased cytoso- lic concentration of calcium ions, or posttranslational modifications of membrane proteins. Calcium signaling is characterized by a rapid increase of its cytosolic concentration. We identify calcium binding sites and characterize the binding in the plasma membrane models of increasing complexity from pure phospholipid bilayers, through cholesterol and peptide rich lipid membranes, to membranes ex- tracted from HEK293 cells. We use Time-Dependent Fluorescent Shift method, which provides direct information on hydration and mobility in defined regions of a lipid bilayer, accompanied with molecular dynamic (MD) simulations, which give molecular details of the studied interactions. The initial step of signaling mediated by PAG protein is its double palmi- toylation. We investigate changes of the biophysical properties of both the lipid membrane and the peptide itself upon the incorporation of the palmitoyls. Em- ploying all atom MD simulations, we study inter- and intramolecular interactions as well as changes in membrane hydration, thickness, or lipid ordering. The second part of the thesis, realized in a direct collaboration with a phar- macological...

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