This thesis asks for the role of signs in Aristotle's theory of knowledge. The great part of semiotic literature is restricted on the interpretation of the works De Interpretatione, which explains the theory of symbols, and Analytica Priora, which explains the theory of signs. In Aristotle's words, theory of signs is based on the theory of knowledge submitted in De Anima. However, semioticians are not able to define the exact part of this work which is being linked, therefore they only neglect this link. The aim of this thesis is to find how much the conception of knowledge submitted in De Anima works or does not work with the notion of representation, and which role Aristotle's notions of sign (sémeion) and symbol (symbolon) take in that issue. Keywords: Aristotle, De Interpretatione, Analytica Priora, De Anima, history of semiotics, knowledge, signs.

Cardiac surgery is known to initiate a complex physiological response with the immune system activation (SIRS), neurohormonal response, metabolic changes, coagulopathies etc. SIRS is triggered by tissue injury, myocardial ischemia, reperfusion, use of anaesthesia, cardioplegia, extracorporeal circuit etc. Excessive immune system activation is associated with progression of SIRS, life-threatening multi-organ dysfunction (MOD), and increased morbidity/mortality in the postoperative period. The immune system response is regulated and terminated by both cellular and humoral regulatory and inhibitory mechanisms including changes in expression of in our study monitored molecules: CD200/CD200R, sCD200R and CD95/CD95L. Methods: The study included the measurement the expression of CD95, CD95L, CD200R, and sCD200R molecules in granulocyte and monocyte populations in blood samples of 30 patients who underwent heart surgery using CPB. Samples collected before surgery, after surgery, and in the postoperative period (1st , 3rd , 7th day) were analysed by flow cytometry and sCD200R by ELISA. Results: We discovered a significant increase in the percentage of granulocytes expressing inhibitory molecule CD200R (from 5% to 17.8%) instantly after surgery. It might be presumed that these cells are less susceptible to...

Mgr. Martin Charvát Deleuze's asignifying semiotics Disertační práce Abstract: In the thesis I am trying to prove that Gilles Deleuze's philosophy must be considered in respect of his analysis of sign. Deleuze's philosophy is thus inseparable from his semiotics which I would like to show on the figure of philosophy as symptomatology. If we understand sign as a symptom we are also standing on the semiotic level. Signs are expressions of ways of life, of our understanding of the world around us. The problem of Deleuze's semiotics (which is connected with the problem of expression) leads us to the problem of genesis. In this respect the genesis is united with the concept of pure difference. Key words: Deleuze, Gilles - signs - semiotics - genesis - difference

Mgr. Martin Charvát Deleuze's asignifying semiotics Disertační práce Abstract: In the thesis I am trying to prove that Gilles Deleuze's philosophy must be considered in respect of his analysis of sign. Deleuze's philosophy is thus inseparable from his semiotics which I would like to show on the figure of philosophy as symptomatology. If we understand sign as a symptom we are also standing on the semiotic level. Signs are expressions of ways of life, of our understanding of the world around us. The problem of Deleuze's semiotics (which is connected with the problem of expression) leads us to the problem of genesis. In this respect the genesis is united with the concept of pure difference. Key words: Deleuze, Gilles - signs - semiotics - genesis - difference

Colorectal cancer is one of the most common type of malignity. Despite of the existence of numerous studies focused on this carcinoma, there are still many unknown features regarding its diagnosis, treatment or prognosis. In the thesis we focused on the identification of novel prognostics markers that could be useful for the stratification of patients based on the disease outcomes. In the first study we immunohistochemically assessed expression of two proteins associated with cancer stem cells in the samples of primary colorectal cancer and matched liver metastasis. Goal of the study was to evaluate relation among expression of CD44 and CD133 and overall survival and disease free interval in our set of patients. We observed that increased ratio of CD133 positive compared to CD133 negative tumor glands resulted in longer disease free interval, finding which is opposite to the general view on the CD133 role in the cancer development. Our hypothesis is that we analyzed confined group of patients and followed a bit different goal, where we measured ratio between positive and negative glands in the view-field and not the intensity of staining as the previous studies did. Our second study was focused on the transcriptional analysis of the selected set of twelve genes using frozen samples from colorectal...

Diploma thesis deals with semiotics of advertising media campaigns of sport clubs AC Sparta Praha and HC Sparta Praha in the season 2013/2014. Both of the clubs celebrated an anniversary this season: AC Sparta Praha celebrated 120 years since its foundation, HC Sparta Praha celebrated 110 years. That was a reason why media campaigns were intensive and referred to the glorious history of the clubs. The Diploma thesis research is focused on meanings encoded into the campaigns and attempts to find out which verbal and non-verbal signs create the term "Sparta". The Author tries to find out if there is the same semiotic base for both clubs which operate with the same name and elementary signs. Diploma thesis defines contemporary "myth of Sparta" in Czech sport area. Theoretical part occupies with contemporary status of sport in the society, analytical part deals with the media campaigns of both clubs from semiotic perspective.

Genetic relationship was analyzed between type traits and longevity measures in dual-purpose cattle. Data from 91 486 Czech Fleckvieh cows first calved between 2003 and 2009 were used. Longevity was defined as the actual number of lactations initiated per cow and also as functional longevity, which incorporated an adjustment to account for variation in voluntary culling based upon milk production. Lifetime performance was defined as cumulative milk production through the 6th parity. All cows were scored for conformation traits during their first lactation. Genetic correlations between these traits and longevity measures were estimated by bivariate analysis using the DMU variance component program package. Type trait heritabilities ranged from 0.30 to 0.59, while heritabilities for longevity and functional longevity were 0.06 and 0.05, respectively. Heritability of lifetime performance was 0.08. Genetic correlations between type traits and longevity measures ranged from low to intermediate values. Genetic correlations of the measured body size traits to the real and functional longevity ranged from ?0.06 to ?0.29, for udder traits from ?0.02 to 0.33, and for foot and leg traits from ?0.03 to 0.17. Genetic correlations between the measured body size traits and lifetime performance ranged from ?0.03 to ?0.30, for udder traits from 0.05 to 0.47, for foot and leg traits from ?0.07 to 0.15. Genetic correlations of composite trait scores for frame, muscularity, feet and legs, and udder with longevity traits ranged from ?0.20 to 0.41 and for lifetime performance ?0.14 to 0.51. The highest genetic correlations between a type trait and functional longevity were for composite udder score (0.25), feet and legs (0.26), and udder depth (0.33), suggesting that these traits could serve as indicators of functional longevity. We conclude that selection based upon easily and inexpensively measured type traits could improve functional longevity of cows as well as lifetime milk production.

The thesis deals with the issue of low achieving readers and appropriate corrective approaches. The theoretical part addresses in detail the characteristics and difficulties of low achieving readers as well as suitable corrective action. In the research part pupils are divided into groups according to their shortcomings and in each group the pupil´s qualitative and quantitative errors in their reading performance are analyzed and then a corrective action is proposed. The research survey is carried out using comprehensive reading diagnostics for pupils in the third class at elementary school.

This thesis deals with Czech and Italian punctuation. The aim is to compare the rules of the punctuation usage in the Czech language with the rules in the Italian language. In the first, theoretical, part there are firstly introduced the sources on which the whole work is based. Then the very notion of punctuation is explained from the both Czech and Italian perspective. Next, there is defined which particular punctuation marks are going to be further examined. The following chapters provide a list of rules of the punctuation usage in Czech and Italian with an emphasis on the similarities and the differences between the two languages. The work also tries to offer a comprehensive look at both languages. In conclusion, there is a practical part to verify the acquired knowledge. It is a series of exercises with a key of the correct answers.

Within the final thesis, the main focus is directed towards history of modern dance techniques, their principles and terminology associated with respective time periods. Furthermore, significant personalities of these periods will be introduced. Following chapters will depict underlying conditions in formation of contemporary dance and also terms often associated with such dance practice. Fourth chapter is dedicated to specific figures, that we were able to encounter within studies on the Academy of Performing arts. We will elaborate specific training approaches and moreover try to discover context and influence of modern techniques contained in their work. Last chapter will summarize the influence of modern art techniques on contemporary dance, what they share and also the role of dance in current society.