Global ETD Search

31	Výpočtová analýza rovnání čtvercových tyčí / Computational analysis of leveling of square cross section rods Šebek, František January 2012 (has links) Current requirements in mechanical engineering require more accurate operations and more efficient technologies. The aim of this thesis is the analysis of the leveling of square rods. The main problem is the setting of the leveling machine for the specified material and geometric data so that the initially curved material, which passes through alternatively positioned offset rollers, is leveled as much as possible. The main factor in the leveling process is the plastification of the material used for the redistribution of the residual stress. Based on existing theo-retical knowledge in this field, programs are set up to simulate the passing of the rod through the leveling machine. Further, modifications leading to the improvement of the whole process are presented. Finally, there is a verification of the results which is made independently of the submitted solution and processed by the finite element method.
32	Methylome Analysis: From Computation Workflow Development to Implementation in a Breast Cancer Prevention Trial Frankhouser, David E. January 2017 (has links) No description available. Bioinformatics Biomedical Research DNA methylation breast cancer bioinformatics next-generation sequencing omega-3 fatty acids bisulfite methylcap-seq clinical research biomarker computational analysis cancer prevention treatment therapy study design
33	Trauma in the Syntax: Trauma Writing in David Foster Wallace's Infinite Jest Alyssa Caroline Fernandez (11181666) 26 July 2021 (has links) <p>This project presents a case study of postmodern trauma, working at the boundaries of the humanities and computer science to produce an in-depth examination of trauma writing in David Foster Wallace’s novel <i>Infinite Jest</i>. The goal of this project is to examine the intricacies of syntax and language in postmodern trauma writing through an iterative process I refer to as <i>broken reading</i>, which combines traditional humanities methodologies (close reading) and distant, computational methodologies (Natural Language Processing). Broken reading begins with close reading, then ventures into the distant reading processes of sentiment analysis and entity analysis, and then returns again to close reading when the data must be analyzed and the broken computational elements must be corrected. While examining the syntactical structure of traumatic and non-traumatic passages through this broken reading methodology, I found that Wallace represents trauma as gendered. The male characters in the novel, when recollecting past traumata or undergoing traumatic events, maintain their subject status, recognize those around them as subjects, and are able to engage actively with the world around them. On the other hand, the female characters in the novel are depicted as lacking the same capacities for subjectivity and action. Through computational text analysis, it becomes clear that Wallace writes female trauma in a way that reflects their lack of agency and subjectivity while he writes male trauma in a way that maintains their agency and subjectivity. Through close reading, I was able to discover qualitative differences in Wallace’s representations of trauma and form initial observations about syntactical and linguistic patterns; through distant reading, I was able to quantify the differences I uncovered through close reading by conducting part of speech tagging, entity analysis, semantic analysis, and sentiment analysis. Distant reading led me to discover elements of the text that I had not noticed previously, despite the occasional flaw in computation. The analyses I produced through this broken reading process grew richer because of failure—when I failed as an interpreter, and when computational analysis failed, these failures gave me further insight into the trauma writing within the novel. Ultimately, there are marked syntactical and linguistic differences between the way that Wallace represents male and female trauma, which points toward the larger question of whether other white male postmodern authors gender trauma in their writings, too. This study has generated a prototype model for the <i>broken reading </i>methodology, which can be used to further examine postmodern trauma writing.</p> Literature Digital Humanities Linguistics Natural Language Processing Postmodernism (Literature) Postmodern Trauma Theory Trauma Close Reading Distant Reading Computational Analysis Natural Language Processing NLP Syntax Syntax Analysis Sentiment Analysis David Foster Wallace Infinite Jest Hal Incandenza Kate Gompert Katherine Ann Gompert Dominick LaCapra Cathy Caruth American Literature Contemporary Literature Contemporary American Literature Literature Digital Humanities DH
34	Computational analysis of wide-angle light scattering from single cells Pilarski, Patrick Michael 11 1900 (has links) The analysis of wide-angle cellular light scattering patterns is a challenging problem. Small changes to the organization, orientation, shape, and optical properties of scatterers and scattering populations can significantly alter their complex two-dimensional scattering signatures. Because of this, it is difficult to find methods that can identify medically relevant cellular properties while remaining robust to experimental noise and sample-to-sample differences. It is an important problem. Recent work has shown that changes to the internal structure of cells---specifically, the distribution and aggregation of organelles---can indicate the progression of a number of common disorders, ranging from cancer to neurodegenerative disease, and can also predict a patient's response to treatments like chemotherapy. However, there is no direct analytical solution to the inverse wide-angle cellular light scattering problem, and available simulation and interpretation methods either rely on restrictive cell models, or are too computationally demanding for routine use. This dissertation addresses these challenges from a computational vantage point. First, it explores the theoretical limits and optical basis for wide-angle scattering pattern analysis. The result is a rapid new simulation method to generate realistic organelle scattering patterns without the need for computationally challenging or restrictive routines. Pattern analysis, image segmentation, machine learning, and iterative pattern classification methods are then used to identify novel relationships between wide-angle scattering patterns and the distribution of organelles (in this case mitochondria) within a cell. Importantly, this work shows that by parameterizing a scattering image it is possible to extract vital information about cell structure while remaining robust to changes in organelle concentration, effective size, and random placement. The result is a powerful collection of methods to simulate and interpret experimental light scattering signatures. This gives new insight into the theoretical basis for wide-angle cellular light scattering, and facilitates advances in real-time patient care, cell structure prediction, and cell morphology research. light scattering computational analysis pattern analysis pattern recognition cytometry machine learning image processing image analysis single cells optics medical diagnostics lab on a chip wide-angle light scattering shape recognition biomedical image analysis fourier theory fourier transform cellular optics optical simulation scattering simulation inverse scattering problem inverse analysis computational intelligence mitochondria cell morphology cancer scattering theory iterative methods generate and test reverse monte carlo image parameterization structure prediction 3D structure prediction computer science computer engineering electrical engineering
35	Computational analysis of wide-angle light scattering from single cells Pilarski, Patrick Michael Unknown Date No description available. light scattering computational analysis pattern analysis pattern recognition cytometry machine learning image processing image analysis single cells optics medical diagnostics lab on a chip wide-angle light scattering shape recognition biomedical image analysis fourier theory fourier transform cellular optics optical simulation scattering simulation inverse scattering problem inverse analysis computational intelligence mitochondria cell morphology cancer scattering theory iterative methods generate and test reverse monte carlo image parameterization structure prediction 3D structure prediction computer science computer engineering electrical engineering

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