Proefschrift Rijksuniversiteit Limburg, Maastricht. / Auteursnaam op omslag: Harry M. Bakker. Met lit. opg. en een samenvatting in het Nederlands.

Submitted by Hiolanda Rêgo (hiolandar@gmail.com) on 2013-09-16T18:37:13Z No. of bitstreams: 1 Dissertação_Med_Silvana Conceição.pdf: 993066 bytes, checksum: ac16fedc0180b5cad548853e0231eb14 (MD5) / Approved for entry into archive by Flávia Ferreira (flaviaccf@yahoo.com.br) on 2013-10-31T17:04:43Z (GMT) No. of bitstreams: 1 Dissertação_Med_Silvana Conceição.pdf: 993066 bytes, checksum: ac16fedc0180b5cad548853e0231eb14 (MD5) / Made available in DSpace on 2013-10-31T17:04:44Z (GMT). No. of bitstreams: 1 Dissertação_Med_Silvana Conceição.pdf: 993066 bytes, checksum: ac16fedc0180b5cad548853e0231eb14 (MD5) / Tropical Medicine Research Center (TMRC); Instituto Nacional de Ciências e Tecnologia de Doenças Tropicais (INCT-DT); Bolsa de Estudo da CNPq; NIH - National Institute of Health (Grant P50AI30639-16 e R03AI067663-02). / Introdução: A primeira linha de tratamento da leishmaniose tegumentar americana (LTA) é baseada nos derivados do antimonial. A refratariedade ao antimônio é frequente entre os pacientes com LTA. Leishmania (Viannia) braziliensis é a principal causa de LTA no Brasil. A L. (V.) braziliensis causa três formas de leishmaniose na Bahia: leishmaniose cutânea localizada (LC), a mais comum com pequenas lesões auto curáveis até as formas mais grave e de difícil tratamento, a leishmaniose mucosa (LM), e a leishmaniose disseminada (LD). Métodos e Resultados: Neste estudo, foram incluídos 91 casos de LTA (67 LC, 7 LM e 17 LD) de uma região endêmica para L. (V.) braziliensis, chamada Corte de Pedra (CP), no estado da Bahia/Brasil, e os quais apresentaram culturas de parasítos positivas. Foram avaliados: (1) associação entre o genótipo de L.(V) braziliensis e a resposta dos pacientes ao antimoniato de meglumina (Glucantime®); (2) a distribuição geográfica dos pacientes refratários ao glucantime dentro da região afetada; e (3) a resistência da L. (V.) braziliensis ao Glucantime® in vitro. Os parasitas foram genotipados com base no sequenciamento de um único locus polimórfico (que começa na posição 3074 do cromossomo 24) desta população de L. (V.) braziliensis. Para a avaliação da distribuição geográfica dos casos responsivos e refratários, as coordenadas geográficas dos locais de moradia dos pacientes foram adquiridas por GPS e comparados usando o teste de Cusick and Edwards. As coordenadas dos locais de moradia dos pacientes foram plotadas em uma foto de satélite da região para inspeção visual, usando o sistema de informação geográfica (SIG). Foi encontrado que a refratariedade é amplamente distribuída na região, quase que uniformemente, contudo não foi possível detectar associações entre os genótipos dos parasitos e a resposta ao tratamento. A sensibilidade ao antimônio foi avaliada expondo as formas promastigotas da L.(V) braziliensis a concentrações crescentes do antimoniato de meglumina (Glucantime®) in vitro. Os parasitos de pacientes com LM e LD foram significantemente mais resistentes ao antimonial do que aqueles isolados dos casos de LC. Assim, a resistência ao antimônio observada in vitro está de acordo com o que tem sido observado em campo, onde os pacientes com LM e LD tendem a ter uma resposta menor ao tratamento com Glucantime® do que os indivíduos com LC. Embora não tenha sido encontrada associação entre as cepas parasitárias e a resposta ao tratamento nestes pacientes com LTA, na genotipagem dos isolados foi usado um único locus, o qual certamente limitou o poder discriminatório da técnica. Conclusão: Nos estudos futuros, estas associações devem ser repetidas aplicando mais loci polimórficos na genotipagem dos isolados de L. (V.) braziliensis de Corte de Pedra. / Salvador

Capture of the energy in sunlight relies mainly on the use of light-absorbing semiconductors, in solar cells and in water-splitting devices. While solar cell efficiency has increased dramatically since the first practical device was made in 1954, production costs for the most-efficient solar absorbers, III-V semiconductors, remain high. This is largely a result of use of expensive, slow growth methods which rely on hazardous gas-phase precursors. Alternative growth methods are necessary to lower the cost for III-V materials for use in solar cells and improve the practicality of water-splitting devices. The research goal of this dissertation is two-fold: to expand the capabilities of close-spaced vapor transport, an alternative growth method for III-Vs to demonstrate its compatibility with current technologies; and to explore the fundamental chemistry of close-spaced vapor transport as a growth method for these materials. This dissertation surveys plausibly lower-cost growth methods for III-V semiconductors (Chapter II) and presents in-depth studies on the growth chemistry of two ternary III-Vs: GaAs1-xPx (Chapter III) and Ga1-xInxP (Chapter IV). Finally, the growth of GaAs microstructures which could be utilized in a water-splitting device is studied (Chapter V). This dissertation includes previously published and unpublished co-authored material. / 2019-01-09

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The aim of this thesis to analysis factors influencing consumer behavior and his/her purchase decision making when buying vegetables, and its impact on marketing of vegetable in Republic of Yemen. The study depend on number of hypothesis, the most important of them was that there are many cultural, social, and economical factors influencing Yemeni consumer behavior which in turn effect on agricultural marketing in the country. Based on the obtained results it is obvious that in the chosen statistical data about the development in production and consumption of vegetables in the Republic of Yemen, increasing in the cultivated area of vegetables within study period (19952009) led to rise in its production and thus in available to consumption. On the other side there was a deficit in all marketing functions of agricultural products. From the given analysis for factors influencing Yemeni consumer behavior it can be concluded that factors price, occasions, discontent, and time of purchase showed a high degree of influence on the behavior of Yemeni consumer when buying vegetables, while factors habit, display, sorting, and the location of seller suggests medium influence, and the influence was low for wordmouth, for factors quality, personal relationship between consumer and buyer, and recommendation of family and friends the influence was high and medium. On the other hand the small sell units are dominating to buy in Yemen.

This master thesis presents a view of work and impotence of medical clowns in Czech hospital facilities. It unveils the organizational structure and history of the same name company, which sponsors medical clowns in the Czech Republic. It presents all the important parts of complex performance that are essential for medical clowns. Therefore, the clowns are able to visit patients and use their artistic performance to pozitively influence their psychical condition. This leads to patients‘ physical health improvement. The thesis defines „klauniáda“ as a means to reach those goals and presents specific patters of theatrical performace in hospital facilities. It deals with structure of klauniády with use of particular stories, author’s life experience and proffesional researches. It also answers the questions related to the medical clowns‘ contribution.

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