David A. Casta? / Bibliography: leaf [9]. / ONR Contract N00014-76-C-0346.

Die Dissertation behandelt aus unterrichtspraktischen Fragestellungen heraus Gestalt und Anwendungsmöglichkeiten aktuell nutzbarer Lehrwerke des Orgelspiels. Aus der Perspektive einer Lehrtätigkeit des Autors an der Musikhochschule erwächst eine Reflexion zur Funktionalität und Wirksamkeit von Orgellehrwerken nach gegenwärtig zugrunde liegenden Kriterien. Es wird der Frage nachgegangen, inwieweit sich didaktische Zielsetzungen früherer und heutiger Zeit unterscheiden und Thesen zur Verwendung elementarer Orgelschulen aufgestellt. Ausgehend von den Entwicklungen bei der Anwendung von Orgellehrwerken im Verlauf der Musikgeschichte wird sichtbar, dass sich die berufspraktischen Anforderungen innerhalb des Aufgabenbereiches eines Organisten am Beginn des 21. Jahrhunderts spürbar verändert haben. Es wird die Bedeutung interpretatorischer, methodischer, musikwissenschaftlicher und psychologischer Aspekte für den heutigen Verlauf des Unterrichtsprozesses beleuchtet. Zudem wird dargestellt, inwieweit speziell der Orgelunterricht einen Sonderfall im Spannungsfeld gegenwärtiger Instrumentalpädagogik bildet.

This dissertation seeks to explore possible relationships between literature—poetry, in particular—and royal patronage. More specifically, I am here interested in examining the remarkable efflorescence of Sinitic poetry (kanshi) during the reign of Emperor Saga (786-842, r. 809-823), as well as some of its later developments in the private poetry collections of Shimada Tadaomi (828-891) and his pupil Sugawara no Michizane (845-903). The history of Sinitic poetry composed in Japan has been meticulously studied; there is certainly no dearth of research, either in Japanese or in English. Even so, the early ninth century remains somewhat of a mystery. A total of three imperially commissioned anthologies (chokusenshū) of Sinitic poetry and prose were compiled during this time, along with an imperial history—all of which were the direct product of Saga’s personal patronage. Much of his own poetry has been preserved in these anthologies. Despite the existence of hundreds of Sinitic poems, and a contemporary history (also in Sinitic), scholars tend to shy away from this period. This dissertation is an attempt to remedy that situation. As a means of facilitating a broader appreciation of Saga, I have included some material on King Alfred the Great (849-899, r. 871-899), the most well-known Anglo-Saxon king, and oft-celebrated father of the English nation, who was a near contemporary of Saga. Naturally, I have also interwoven some material on Emperor Taizong (598-649, r. 626-649) of the Tang dynasty, whose influence on ninth-century Sinitic poetry (in Japan) has been the focus of some past research. Scholars of East Asian literature, whether they specialize in Chinese or Japanese literature, are familiar with the grand literary and political legacy of this continental sovereign. Both Saga’s poetry as well as his ideal of sovereignty were influenced by the work of Taizong and his lettered vassals. A central assumption informs this work: ninth-century poetry was inevitably political, insofar as it served as a tool whereby authors could enforce or manipulate prevalent power relations within the court. Poetry, therefore, was both dominated by and exercised significant influence over hierarchical networks of patronage. Poetry was also occasional performative, that is, it was recited aloud on public occasions—royal banquets or excursions—before an audience of vassals and courtiers. Saga, as supreme ruler and patron, composed poetry that sought, through its presentation at these banquets, to repeatedly legitimate his own position, while simultaneously appealing to a number of different audiences. Different audiences harbored different expectations, and Saga, adroit politician that he was, strove to please each in turn by adopting a number of poetic voices or personae. This is especially evident after his retirement, when he found it necessary to adopt a different poetic persona more appropriate to his less prominent station. Tadaomi and Michizane, as recognized scholars, loyal vassals, and influential statesmen, received patronage from both sovereigns and high-ranking noblemen. These complex networks of patronage and varied audiences demanded the creation of ever more subtle poetic personae. This dissertation, among other things, is an exploration of how poets of the ninth century adopted different poetic personae in accordance with their intended audiences. The deliberate mixing of various Sinitic genres to achieve this end receives a great deal of attention.

<p>Renal cell carcinoma (RCC) is the most frequently lethal of urological cancers. It arises in the lining of the proximal convoluted tubule of the kidney and is most common in men ages 50–70. Often, partial or radical nephrectomy is needed to effectively treat the disease, leaving patients with reduced kidney function. RCC frequently displays significant radiation resistance, limiting the usefulness of traditional radiation therapy which might spare patients’ normal tissue. The enzyme carbonic anhydrase 9 (CA9), a product of the hypoxia pathway, is found upregulated in the majority of RCC, particularly the clear cell type. It catalyses the dissolution of carbon dioxide into water as bicarbonate and has been linked to increased invasion and migration in RCC tumour cells. The radiation resistance of two RCC cell lines 786-O (human CCRCC) and RAG (murine renal adenocarcinoma) was investigated by the clonogenic assay in the presence of a CA9 inhibitor or silencing RNA. The interference with CA9 by either of these methods significantly sensitizes 786-O cells to the effects of ionizing radiation <em>in vitro</em>. Moreover, fractionation of the dose delivered can increase this sensitization effect. It is hoped that current targeting of CA9 can make radiation therapy a more feasible option in the treatment of RCC.</p> / Master of Science (MSc)

No description available.

Since the nineteenth century the Two Part Inventions have become standard repertoire for piano students. However, piano teachers have often failed to give serious consideration to the suitable selection of Inventions for study. Piano students have commonly formed a dislike for Bach's piano music because of an ungratifying initial experience. There is little material written in English dealing with the Two Part Inventions. Those studies of the Inventions which do exist consist mainly of brief articles in periodicals and limited discussions in piano literature books. Therefore, there seemed to be a need for a systematic collection of pedagogical ideas concerning the Two Part Inventions. In addition, it was felt that an analysis of the problems in each piece and a subsequent graded list of the Inventions would be a step toward a more intelligent and more knowledgeable approach in the teaching of these compositions.

Die Dissertation behandelt aus unterrichtspraktischen Fragestellungen heraus Gestalt und Anwendungsmöglichkeiten aktuell nutzbarer Lehrwerke des Orgelspiels. Aus der Perspektive einer Lehrtätigkeit des Autors an der Musikhochschule erwächst eine Reflexion zur Funktionalität und Wirksamkeit von Orgellehrwerken nach gegenwärtig zugrunde liegenden Kriterien. Es wird der Frage nachgegangen, inwieweit sich didaktische Zielsetzungen früherer und heutiger Zeit unterscheiden und Thesen zur Verwendung elementarer Orgelschulen aufgestellt. Ausgehend von den Entwicklungen bei der Anwendung von Orgellehrwerken im Verlauf der Musikgeschichte wird sichtbar, dass sich die berufspraktischen Anforderungen innerhalb des Aufgabenbereiches eines Organisten am Beginn des 21. Jahrhunderts spürbar verändert haben. Es wird die Bedeutung interpretatorischer, methodischer, musikwissenschaftlicher und psychologischer Aspekte für den heutigen Verlauf des Unterrichtsprozesses beleuchtet. Zudem wird dargestellt, inwieweit speziell der Orgelunterricht einen Sonderfall im Spannungsfeld gegenwärtiger Instrumentalpädagogik bildet.

The Austin Steam Train Association operates a tourist train on a stretch of track in Texas from Cedar Park to Burnet. The diverse assortment of restored cars, some dating back to the 1920s, is pulled most-recently by a diesel engine, No. 442, as Southern Pacific No. 786, the original steam engine, is in the process of being repaired. The train requires more than $1 million annually to operate and would have folded long ago if not for an all-volunteer crew. ASTA staffs the crew of at least 10-15 people per train 105-110 times per year and has been doing so for more than 20 years. During a ride on the train, passengers see a wide variety of scenery, including some relics with historical significance. Among them are several large chunks of granite which fell of trains shuttling the stone decades ago from Marble Falls to Austin for the construction of the capitol building. Trains also carried granite to Galveston after the infamous hurricane hit. ASTA also provides entertainment inside the train. Themes rides sell out months in advance. Murder mystery trips are always hits but the Wine Flyer is gaining popularity. With a layover in Burnet on the Saturday Hill Country Flyers trips, passengers take time to explore a new city, have lunch and maybe do a little quick shopping. ASTA takes the operation of the train seriously and makes safety a priority. ASTA runs the train with fantastic dedication and perseverance and subsequently, generates a rolling work of history for study by families, first-timers and enthusiasts alike on a weekly basis. / text