Thesis (M.N.)--Memorial University of Newfoundland, 2004. / Bibliography: leaves 188-195.

Heart failure (HF) is a serious, life limiting chronic illness and is the most common cause of <30-day hospital readmission, which is costly both in its profound negative impact on patient mortality and quality of life, and in economics. Limited access to care in rural communities increases the prevalence of hospitalizations for heart disease in rural areas. The aims of this project using data mined from Arizona Health Sciences Center Clinical Research Data Warehouse, are to define clinical events (fever, pain, changes in respiratory status, change in level of consciousness, changes in output, bleeding, and suicide ideation) for patients with heart failure, and determine what assessment values are for chronically ill patients and compare to "normal" assessment values for non-chronically ill patients. A literature review was completed to determine how to define clinical events for chronically ill patients with HF, and how decision making is used at home to manage chronic illness. Assessment value data was mined from the clinical research data warehouse and compared to “normal” assessment values, with identification of associations between clinical events and action taken in the hospital. The project results support that there are differences in "normal" assessment values for fever, pain, and change in respiratory status between chronically ill patients with HF, and non-chronically ill patients; there was insufficient data to define bleeding, change in output, or suicide ideation. Impacts to care include earlier recognition of worsening HF symptoms that could result in an earlier call or visit to primary care provider forestalling the need for emergent care and hospital readmission. Application of the mined clinical may inform development of evidenced-based algorithm to guide decision-making at home, and it may also provide the foundation for the development of a tool for patient use to prevent <30-day hospital readmission.

One of the major development problems in the southern African region and South Africa in particular relates to the phenomenon of high failure rates among Small Medium and Micro Enterprises (SMMEs). The important role of SMMEs in creating jobs and incomes is widely acknowledged. SMMEs are relatively inexpensive to establish and have the potential to generate economic growth in the southern African region. One major dilemma of this sector, however, is the short lifespans of SMMEs. Past research has focused on understanding failure of small businesses by mainly identifying factors of failure without subjecting them to step-wise causality testing. This research closes that gap and uses a retrospective study, coupled with the critical realist approach, to understand the causes of the high failure rates of SMMEs. The merit of this approach lies in the attention it gives to an historical understanding of past processes and how a determined effort could be initiated to change the current “historical reality” of the factors behind the failures, specifically in South Africa. A sample comprising 254 owner-managers of SMMEs from the Gauteng, Limpopo and Mpumalanga provinces in the Republic of South Africa as well as from Gaborone in Botswana was subjected to an interview between January 2007 and December 2007. Data were collected by means of a semi-structured research instrument which probed the failure of the interviewees’ businesses across a period spanning seven years between 2000 to 2006. The analysis of the data involved the use of both quantitative and qualitative research methodologies. The findings indicate that four explanatory factors were paramount: “monitoring and control” (factor 1); “experience and planning in finance and marketing” (factor 2); “income constraints” (factor 3), and “cash control” (factor 4). Based on the findings, the following recommendations, if implemented, may assist with lowering the high failure rates: First, the mindsets of the owners of the failed businesses were found to be a fundamental factor in the closure of the businesses. Radical programmes for changing these mindsets are therefore critical. Second, with the mindsets changed, venture skills training programmes could then be introduced involving learning and training. By so doing, it is hoped that the void left by low levels of education and business experiences in the SMME sector would be reduced. Finally, at the policy-making level, the required assistance should be tilted more towards government-corporate involvement, in assisting the SMME sector in the form of financial subsidies for start-up capital, small business-builder programmes, and business mentoring programmes, among others. / Thesis (PhD)--University of Pretoria, 2011. / Business Management / unrestricted

The purpose of this study was to explore how college students reflectively describe their learning failure experiences, along with the major themes of those experiences. Through a series of in-depth interviews, four narrative cases written from the perspective of two college students were developed. These four cases were then carefully analyzed and cross-examined to generate a deeper understanding of college student learning failures. This study explored approximately 78 themes related to these four cases, which led to the development of six key components of college student learning failure experiences: Recognizing Learning Failures, Evaluating Learning Failures, Attributions for Learning Failures, Self-Discovery Through Learning Failure, Past Experience and Future Expectations, and Social Influence. These components helped to define an initial framework for guiding future research into college student learning failure experiences.

Forskning om entreprenörskap fokuserar på framgång som ignorerar den höga felfrekvensen av Nya företag. Många nya företag misslyckas så hur entreprenörer hantera det när deras företag misslyckas? Framgångsrika entreprenörer prisar fördelarna med misslyckande som en värdefull lärare. Resultatet av misslyckande regelbundet fylld med ekonomiska, sociala, psykologiska och fysiska hälsoproblem. Syftet med denna forskning är att bedöma företagets misslyckande upplevelser för företagare, från det ögonblick resultatet genom att  återhämtningen för att hantera företagande fel och avsluta för påverkan av den slutna företag.  I denna forskning aspekter av livet som påverka av entreprenörs fel undersöka ekonomiskt, socialt och psykologiskt att belysa faktorer som kan påverka mängden av kostnaderna för ett misslyckande. Därefter beskriver forskningen hur entreprenörer lära av misslyckanden. Den presenterar på resultaten av företagets misslyckande, inklusive hantera fel och återhämtning tillsammans med kognitiva och beteendemässiga utfall. / Research on entrepreneurship focuses on success which ignores the high failure rate of new ventures. Many new ventures fail so how entrepreneurs deal with it when their venture    fails? Successful entrepreneurs praising the advantages of failure as a valuable teacher. The result of failure is regularly filled with economic, social, psychological, and physical health disorder. The aim of this research is to assessment venture failure experiences for entrepreneurs, from the instant result through to recovery for coping with entrepreneurial failure and exit for impact of the closed venture. In this research, aspects of life affected by entrepreneurial failure examine economically, socially and psychologically in highlighting factors that may influence the amount of costs of failure. Next, the research describes how entrepreneurs learn from failure. It presents on the outcomes of venture failure, including coping with failure and recovery together with cognitive and behavioral outcomes. The main objective of the research study is to understand the failure from entrepreneurs    who have experienced it and also to make a theoretical framework of failure based on entrepreneurial venture failure experiences. Every entrepreneur starts up a venture with high expectations of achieving success. Failure can be emotionally disturbing, devastating,  painful, distressing and costly for the entrepreneur who may have to aspect the stigma of failure and the loss of reputation. The entrepreneur can get involved in grief, heartache, anxiety, depression, shame, rejection and discouragement (Politis &amp; Gabrielsson, 2009). The purpose of the research is to investigate how entrepreneurs realize and react to venture  failure. Moreover, entrepreneurs are looking for positive aspects of failure as enhancing experiences that help their coping with entrepreneurial failure, learning from failure, the willingness to begin a new venture and also trigger changes in upcoming decision-making. The purpose of the research is to take a view of the existed experience of failure, taking into consideration impact from the entrepreneurship.

This dissertation is to obtain an overall understanding of the crack path selection in adhesively bonded joints. Using Dow Chemical epoxy resin DER 331® with various levels of rubber concentration as an adhesive, and aluminum 6061-T6 alloy with different surface pretreatments as the adherends, both symmetric and asymmetric double cantilever beam (DCB) specimens are prepared and tested under mixed mode fracture conditions in this study. Post-failure analyses conducted on the failure surfaces indicate that the failure tends to be more interfacial as the mode II component in the fracture increases whereas more advanced surface preparation techniques can prevent failure at the interface. Through mechanically stretching the DCB specimens uniaxially until the adherends are plastically deformed, various levels of T-stress are achieved in the specimens. Test results of the specimens with various T-stresses demonstrate that the directional stability of cracks in adhesive bonds depends on the T-stress level. Cracks tend to be directionally stable when the T-stress is compressive whereas directionally unstable when the T-stress is tensile. However, the direction of crack propagation is mostly stabilized when more than 3% mode II fracture component is present in the loading regardless of the T-stress levels in the specimens. Since the fracture sequences in adhesive bonds are closely related to the energy balance in the system, an energy balance model is developed to predict the directional stability of cracks and the results are consistent with the experimental observations. Using the finite element method, the T-stress is shown to be closely related to the specimen geometry, indicating a specimen geometry dependence of the directional stability of cracks. This prediction is verified through testing DCB specimens with various adherend and adhesives thicknesses. By testing the specimens under both quasi-static and low-speed impact conditions, and using a high-speed camera to monitor the fracture sequence, the influences of the debond rate on the locus of failure and the directional stability of cracks are investigated. Post-failure analyses suggest that the failure tends to be more interfacial when the debond rate is low and tends to be more cohesive when the debond rate is high. However, this rate dependence of the locus of failure is greatly reduced when more advanced surface preparation techniques are used in preparing the specimens. The post-failure analyses also reveal that cracks tend to be more directionally unstable as the debond rate increases. Finally, employing interface mechanics and extending the criteria for the direction of crack propagation to adhesively bonded joints, the crack trajectories for directionally unstable cracks are predicted and the results are consistent with the overall features of the crack paths observed experimentally. / Ph. D.

Previous research on quality of life (QOL) and its relation to BNP levels in heart failure (HF) has been widely studied. However, the impact of physicians' knowledge of BNP levels at time of clinic visit on QOL and hospital length of stay (LOS) has yet to be fully investigated. The purpose of this study were to determine if physicians' knowledge of BNP levels affected a change in QOL scores at 90 days and reduce hospital length of stay among heart failure patients. QOL data from HF clinic patients (N = 108, 67.5 ± 12.3, 56% male, ejection fraction 26.5 ± 8.2) were analyzed. QOL was measured at time of clinic visit (T1) and at 90 days (T2) using the Minnesota Living with Heart Failure Questionnaire (MLHFQ). An independent t-test was utilized to compare the two groups. Findings: Both groups were comparable regarding demographic and baseline characteristics. There was no significant association observed between the experimental and control group at 90 days, although the data indicated a decrease in the mean QOL scores at 90 days (37.46 ± 28.67) as compared to the mean QOL scores at baseline (46.87 ± 29.63) for both groups. Because the QOL scale is reversed, this indicated that there was a positive change in QOL scores during the 90 day time interval. Hospital LOS was similar for both groups (mean=3 days). BNP levels were significantly correlated with both baseline QOL scores (r=.25, p=.01) and physical subscale scores (r=.24, p=.01). Mortality was higher in the control when compared to the experimental group (t=1.99, df=90, p=.04). Conclusion: While physicians' awareness of BNP levels had not shown a significant change in QOL at 90 days, patients' QOL might already have been quite positive. Chronic HF patients may have adapted to their disease and have adjusted their perception of their QOL. Therefore, QOL may be a stable construct at this time. Findings may have been different on newly diagnosed HF patients since they may not have adapted to their health condition.

Purpose The  purpose  of  this  thesis  is  to  identify  the  role  of positive  emotions  in  project  failure  and  how  these emotions  affect  corporate  entrepreneurs´  decision-making and motivation. Theoretical perspective Entrepreneurial Failure, Emotions, Appraisal Theory, Attribution  Theory,  Psychological  Ownership,  Psychological Capital. Empirical foundation Seventeen respondents from 14 entrepreneurial companies  were  interviewed to identify  the role of positive emotions in  project failure and  their impact  on corporate entrepreneurs’  decision-making  and motivation in subsequent projects. Interviews were conducted by phone (1), audio conference (2), video conference (3) and face-to-face interviews (4). Conclusion We  offer  a  model,  which  shows  the  three  positive emotions that were found to be experienced in project failure, namely relief, confidence and challenge and their  impact  on  corporate  entrepreneurs’  decision-making and motivation in subsequent projects.

Introduction: Chronic kidney disease (CKD) and congestive heart failure (CHF) patients have higher serum B-type natriuretic peptide (BNP), which alters the test interpretation. We aim to define BNP cutoff levels to diagnose acute decompensated heart failure (ADHF) in CKD according to CHF subtype: heart failure with preserved ejection fraction (HFpEF) and heart failure with reduced ejection fraction (HFrEF). Material and methods: We reviewed 1,437 charts of consecutive patients who were admitted for dyspnea. We excluded patients with normal kidney function, without measured BNP, echocardiography, or history of CHF. BNP cutoff values to diagnose ADHF for CKD stages according to CHF subtype were obtained for the highest pair of sensitivity (Sn) and specificity (Sp). We calculated positive and negative likelihood ratios (LR+ and LR–, respectively), and diagnostic odds ratios (DOR), as well as the area under the receiver operating characteristic curves (AUC) for BNP. Results: We evaluated a cohort of 348 consecutive patients: 152 had ADHF, and 196 had stable CHF. In those with HFpEF with CKD stages 3–4, BNP < 155 pg/ml rules out ADHF (Sn90%, LR– = 0.26 and DOR = 5.75), and BNP > 670 pg/ml rules in ADHF (Sp90%, LR+ = 4 and DOR = 6), with an AUC = 0.79 (95% CI: 0.71–0.87). In contrast, in those with HFrEF with CKD stages 3–4, BNP < 412.5 pg/ml rules out ADHF (Sn90%, LR– = 0.19 and DOR = 9.37), and BNP > 1166.5 pg/ml rules in ADHF (Sp87%, LR+ = 3.9 and DOR = 6.97) with an AUC = 0.78 (95% CI: 0.69–0.86). All LRs and DOR were statistically significant. Conclusions: BNP cutoff values for the diagnosis of ADHF in HFrEF were higher than those in HFpEF across CKD stages 3–4, with moderate discriminatory diagnostic ability. / Revisión por pares

The restaurant industry plays an essential role in the U.S. economy. Approximately 26% of small- and medium-sized enterprise restaurants fail during their first year of business operation and 60% cannot sustain beyond 3 years. The objective of this multiple case study was to explore the strategies that small- and medium-sized restaurant owners used to financially sustain business beyond 5 years. The purposive sample consisted of 4 successful restaurant owners who have been in operation for at least 5 years in the southern region of the United States. The general systems theory was the conceptual framework of this study. The data were collected from semistructured interviews, cash flow statement, and profit and loss statements. Member checking and transcript review were used to strengthen the credibility and trustworthiness. The 3 themes that emerged from methodological triangulation after completing the Yin's 5 steps of data analysis were market research, great customer service, and having passion. The findings of this study might serve as a guide for current and future SME restaurant owners to financially sustain business beyond 5 years. The findings of the study may contribute to social change as successful small- and medium-sized enterprise restaurant owners would help address unemployment issues by generating additional jobs and building wealth for themselves, their employees, communities, and the local economy.