A method of locating structural damage is developed and tested to aid in the evaluation of structural health. This method will help minimize the cost of structural inspection and repair by informing engineers of where damage, due a seismic event, has occurred before the removal of finishes for visual inspection. This thesis begins to answer the question “can structural damage be detected solely through analysis of experimentally measured mode shapes?” The work encompasses construction of a test structure, with three braces that can be repeatedly engaged or dis-engaged, thus allowing for testing of a variety of braced configurations. For this thesis, damage is assumed to cause a change in stiffness. Experimental testing is conducted to acquire mode shapes and frequencies for the 6 dominant modes of the test structure. Lastly, the data is analyzed to identify the configuration of braces engaged on the structure. The accuracy of the method is assessed by the number of configurations that it correctly predicts and the confidence of the predictions.

This Master thesis deals with construction design of pop-up turntable with load capacity 120 tons and 1500 mm stroke. The driveline will supply by combination of hydromotor and planetary gearbox.The first part of this thesis deals with research in the field of current offer of pop-up turntables and construction elements used in pop-up turntables.Then is acceded to design of 3 different construction variants, of which is chosen one based on evaluation properties of each variant. After this part, follows on constuction design of chosen variant, including both desinging and calculating part. Part of the thesis is also required technical drawing documentation.

This diploma thesis deals with the strength analysis of three-axle frame for containers with driving drum. Total weighth of the trailer is 27 000 kg. Finite elemenths method was used for this calculation in programme I-DEAS. Dangerous parts of the construction were examined and their optimization was proposed. The final part consists of the drawing documentation of the recomended design changes.

The task of this diploma thesis is technical solution for deformation measuring of motorcycle components. By reason of the technical discretion, technology of measurement was changed to another, using image processing. Retrieval which describes fundamental principle of method named photogrammetry and the main conditions of measuring. For a practical testing the carbon composite tube of main motorbike fork was used. It was loaded a with a bending moment. Due to measuring technology was changed, so the design of loading bench was change too. In the end of diploma thesis is appreciation of practical experience discovered in writing of this thesis.

This work deals with the design of chassis for race car category E2 made from aluminium honeycomb sandwich, design of roll cage and conception of engine mount. In the text are FEM analysis, which are focused on torsional rigidity of chassis and strength properties of roll cage.

KIF1A is a molecular motor for membrane-bound cargo important to the development and survival of sensory neurons. KIF1A dysfunction has been associated with several Mendelian disorders with a spectrum of overlapping phenotypes, ranging from spastic paraplegia to intellectual disability. We present a novel pathogenic in-frame deletion in the KIF1A molecular motor domain inherited by two affected siblings from an unaffected mother with apparent germline mosaicism. We identified eight additional cases with heterozygous, pathogenic KIF1A variants ascertained from a local data lake. Our data provide evidence for the expansion of KIF1A-associated phenotypes to include hip subluxation and dystonia as well as phenotypes observed in only a single case: gelastic cataplexy, coxa valga, and double collecting system. We review the literature and suggest that KIF1A dysfunction is better understood as a single neuromuscular disorder with variable involvement of other organ systems than a set of discrete disorders converging at a single locus. / National Institutes of Health / Revisión por pares

The present study evaluated the effects of utilizing derived relational responding protocols to teach non-arbitrary frames of opposition, comparison and distinction to two children with autism across tactile, auditory, and olfactory sensory modalities. Both participants were successful in demonstrating accurate responding across all skill programs, which included the demonstration of transfers of stimulus function. The results for both participants suggest that the programs were effective in fostering skill acquisition among individuals with ASD using the relational frames of opposition, distinction, and comparison by utilizing stimuli with sensory qualities of tactile, olfactory, and auditory modalities respectively.

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Due to the massive amount of postconsumer clothing waste, there is a great opportunity to utilize the discarded garments through playful methods push the imagination towards new innovative solutions. This work aims to redefine and give the discarded garments new values through exploring garment definition through characteristic lines of dress as a filter to view a garment. It deals with questions such as, what defines a specific garment and how many lines needs to be added to understand what it is. It was resulted in creation of an archive consisting of 32 pieces which shows the potential in changing the perception of unwanted/discarded garments, by literally reframing them. This work propose a new method for reusing garments without taking the garments apart but instead look at all the potential that is given within it.

I have used weaving as a method to investigate connections between this craft and architecture. The project can be divided into four parts: The first part is a research phase starting from the etymology of the word textile, which derives from the latin word texere which means - to weave, to join, to build, to construct etc. Following the spirit of Gotfried Semper and his ideas in his book “The four elements of architecture” I have built frames to learn the principles of weaving. The second part is a basic research of an attempt to create a prototype for a structural element that is based on previous studies. In part three I illustrate potential areas of use of the elements. In the final conclusive part I reflect upon my work and what I have learned during the project.