The purpose of this research is to demonstrate the ability to generate and characterize a nanometer sized aerosol using solutions, suspensions, and a bulk nanopowder, and to research the viability of using an acoustic dry aerosol generator/elutriator (ADAGE) to aerosolize a bulk nanopowder into a nanometer sized aerosol. The research compares the results from a portable scanning mobility particle sizer (SMPS) to the more traditional method of counting and sizing particles on a filter sample using scanning electron microscopy (SEM). Sodium chloride aerosol was used for the comparisons. The sputter coating thickness, a conductive coating necessary for SEM, was measured on different sizes of polystyrene latex spheres (PSLS). Aluminum oxide powder was aerosolized using an ADAGE and several different support membranes and sound frequency combinations were explored. A portable SMPS was used to determine the size distributions of the generated aerosols. Polycarbonate membrane (PCM) filter samples were collected for subsequent SEM analysis. The particle size distributions were determined from photographs of the membrane filters. SMPS data and membrane samples were collected simultaneously. The sputter coating thicknesses on four different sizes of PSLS, range 57 nanometers (nm) to 220 nm, were measured using transmission electron microscopy and the results from the SEM and SMPS were compared after accounting for the sputter coating thickness. Aluminum oxide nanopowder (20 nm) was aerosolized using a modified ADAGE technique. Four different support membranes and four different sound frequencies were tested with the ADAGE. The aerosol was collected onto PCM filters and the samples were examined using SEM. The results indicate that the SMPS and SEM distributions were log-normally distributed with a median diameter of approximately 42 nm and 55 nm, respectively, and geometric standard deviations (GSD) of approximately 1.6 and 1.7, respectively. The two methods yielded similar distributional trends with a difference in median diameters of approximately 11 - 15 nm. The sputter coating thickness on the different sizes of PSLSs ranged from 15.4 - 17.4 nm. The aerosols generated, using the modified ADAGE, were low in concentration. The particles remained as agglomerates and varied widely in size. An aluminum foil support membrane coupled with a high sound frequency generated the smallest agglomerates. A well characterized sodium chloride aerosol was generated and was reproducible. The distributions determined using SEM were slightly larger than those obtained from SMPS, however, the distributions had relatively the same shape as reflected in their GSDs. This suggests that a portable SMPS is a suitable method for characterizing a nanoaerosol. The sizing techniques could be compared after correcting for the effects of the sputter coating necessary for SEM examination. It was determined that the sputter coating thickness on nano-sized particles and particles up to approximately 220 nm can be expected to be the same and that the sputter coating can add considerably to the size of a nanoparticle. This has important implications for worker health where nanoaerosol exposure is a concern. The sputter coating must be considered when SEM is used to describe a nanoaerosol exposure. The performance of the modified ADAGE was less than expected. The low aerosol output from the ADAGE prevented a more detailed analysis and was limited to only a qualitative comparison. Some combinations of support membranes and sound frequencies performed better than others, particularly conductive support membranes and high sound frequencies. In conclusion, a portable SMPS yielded results similar to those obtained by SEM. The sputter coating was the same thickness on the PSLSs studied. The sputter coating thickness must be considered when characterizing nanoparticles using SEM. Finally, a conductive support membrane and higher frequencies appeared to generate the smallest agglomerates using the ADAGE technique.

Certain N95 FFR models that staple the head straps directly onto filtering material are commercially available. This method of assembly can tear or reduce fiber density in the immediate area surrounding the staple punctures. Five N95 FFR models were evaluated to determine if staple punctures on the filter medium reduce the protection offered by the respirators. Total penetrations were measured with the staple punctures intact and when stretching the head straps a distance equivalent to a 95% male head circumference. Filter penetration were measured by sealing the staple punctures. Aerosols of 200, 500, and 1000 nm were used to challenge respirators at 28 and 85 Liter/min flow rates. Staple punctures were visually inspected by macrophotography with a light source on the opposing side of the punctures. Three FFR models had greater mean leakages than the remaining two. However, only two FFR models had statistically significant greater total penetrations than filter penetrations. Pulling the head straps increased total penetration, but was not statistically significant. Filter penetrations were greatest at 85 Liter/min and 200 nm, while leakages were greatest at 28 Liter/min flow rate and 1000 nm. Leakage through the staple punctures had greater contributions to total penetration than filter penetration allowing a greater percentage of 1000 nm particles into the breathing zone. Leakage was dependent on the tearing of the filter material or the reduction of fiber density near the puncture, regardless of filter efficiency. Total penetration to filter penetration ratios showed that leakage was greater than filter penetration 15 fold for 1,000 nm. This value is similar to what has been reported for face seal leaks on human subjects. Protection factors were reduced from ~930 to ~60 when the staple punctures created a tear. N95 FFR with stapled head straps that puncture the filter medium should be avoided because they can reduce protection to the user.

[pt] O impactador inercial em cascata é um instrumento no qual uma amostra de ar e poluentes (aerossóis) é obrigada a percorrer um trecho contendo obstáculos, chamados placas de impactação. Os obstáculos forçam o jato a mudar de direção, mas como as partículas têm maior inércia do que o fluido, não acompanham as linhas de corrente do escoamento e acabam por depositar-se sobre estes obstáculos. Diferenças na geometria envolvendo diminuição de área de passagem de escoamento e conseqüente aumento de velocidades, fazem com que, a cada estágio, partículas de diâmetros menores sejam coletadas. O desafio é projetar um instrumento que maximize a eficiência de coleta, diminuindo as perdas por deposição indesejável de partículas nas paredes, recirculações e outros efeitos. Nesta Dissertação de Mestrado foi realizado o projeto de um impactador de três estágios coletando, respectivamente, partículas com diâmetro aerodinâmico de 10, 2,5 e 1 (mi)m, operando com vazão de 30 lpm (litros por minuto) e pressão atmosférica. Na análise de desempenho do instrumento, foram realizadas simulações numéricas com o objetivo de analisar características do escoamento e da trajetória de partículas e levantar as curvas de eficiência de coleta. Foram realizados, também, testes experimentais reproduzindo condições de uso com o intuito de levantar as curvas de eficiência reais. Os resultados numéricos e experimentais foram comparados e apresentam-se ao final, conclusões sobre o desempenho do instrumento e recomendações para trabalhos futuros. / [en] Impactors are simple devices in which a sample flows of air and pollutants flow around an obstacle, called impaction plate. Particles with sufficient inertia will slip across the flow streamlines and impact on the obstacle. Particles with less inertia will follow the airflow away from the impaction surface. Inertial cascade impactors have more than one impaction area. Each one has an impaction plate and a nozzle plate. From one stage to the other, the nozzle diameters become smaller and, consequently, the velocities are higher. This allows for the collection of smaller particles. The challenge is to design an instrument with the higher collection efficiency as possible, reducing wall losses, recirculation regions and other effects. In this study a 3-stages inertial cascade impactor was designed and tested. The cut-point aerodynamic diameters for each stage were 10, 2.5 and 1 (mi)m, respectively, when operating with a flow rate of 30 l/min at atmospheric pressure. To evaluate the instrument, some numerical simulations were performed. They provided results for the flow field, particle trajectories and the collection efficiency curves. Experimental tests were also done to allow for the determination of the real efficiency curves. The numerical and experimental data were compared. Finally, the conclusions of the work and recommendations for future studies are presented.

Research Doctorate - Doctor of Philosophy (PhD) / This work reports the deposition onto high voltage insulators and correlation to atmospheric corrosivity measurement. This work includes corrosion studies at 15 sites in New Zealand (1,816 tests) for in excess of 12 months, and co-operative research in South Africa. In addition, to confirm the relevance and transportability of this proposed model, a review of the published international data on deposition rates on insulators was conducted. It was noted that the deposition rate of airborne pollutants onto a surface is dependent upon the true surface area facing the wind and the aerodynamic properties of the surface. Such is the effect that surfaces with minimal exposure to the wind such as horizontal plates, have been shown to be poor collectors of deposits while vertical plates are more efficient, followed by high voltage glass insulators, the ISO9223 salt candle, and the largest collector is the Direct Dust Deposit Gauge. This study found that the ISO9223 wet salt candle and the average annual deposition rate on the High Voltage Glass insulator bottom surface (unenergized) provided relatively similar deposition results. The deposition onto insulator surfaces may be a more relevant method as it replicates deposition on large surfaces. This Equivalent Salt Dry Deposition (ESDD) method for HV insulators is an all inclusive measure of the airborne pollutants deposition rate and converts the total deposited material into a single value equivalent to that of salt, even though the deposit may consist of sulphur, marine salts, nitrates, and other conductive pollutants. The measured deposition rate on the sheltered insulator bottoms at 85 sites around the world predicted 87% of the ISO corrosivity categories (based on zinc corrosion) for these sites. Results from equatorial Asia appear to be non-compliant and warrant further investigation. The ESDD values are now being quoted from around the world, by electrical engineers who use the recently revised CIGRE methodology, to determine the probability of arc-over (shorting to earth) of high voltage cables due to pollution build-up on insulators. The implications from this research are significant, with the cost of atmospheric corrosivity studies becoming prohibitively expensive, this method converts technically valid surface deposition results from the electrical engineers from around the world (provided at no cost), to valid empirical corrosivity rates from often remote locations.

This thesis examines the particle capture, fibre wetting and droplet flow processes within wet filters collecting solid and liquid aerosols and within filters collecting only liquid aerosols. The processes involved in this type of filtration were examined through a series of experiments and models developed to describe the behaviour of fibre/liquid systems. This work can be summarized in 4 categories: (1) The bounce and immediate re-entrainment of liquid and solid monodisperse aerosols under a stable filtration regime (pre cake formation) by wet and dry fibrous filters. In this work it was found that the solid particles generally exhibited a lower fractional filtration efficiency than liquid particles (of the same size), although this difference decreased in the smaller size fractions. However, for the wet filtration regime (each fibre of the filter was coated by a film of water), no significant difference in filtration efficiency was detectable between solid and liquid aerosols. Either the bounce effect of the particles is inhibited by the liquid film, or the filtration conditions in the wet filter are so different that the aerosol properties are less significant with respect to capture. (2) A microscopic study of the effect of fibre orientation on the fibre wetting process and flow of liquid droplets along filter fibres when subjected to airflow and gravity forces was conducted. The flow of the liquid collected by the fibres was observed and measured using a specially developed micro-cell, detailed in the thesis. The experimental results were compared to a theoretical model developed to describe the flow of droplets on fibres. The theory and experimental results showed a good agreement. A sensitivity analysis of the model was performed which showed the droplet radius to be the most significant parameter. The model has the potential to improve filter self-cleaning and minimise water use. (3) An experimental study of the capture of solid and liquid (oil) aerosols on fibrous filters wetted with water. Variable quantities of liquid irrigation were used, and the possibility for subsequent fibre regeneration after clogging or drying was also studied. It was found that self-cleaning (removal of solid aerosols by water) occurred even under heavily dust-laden conditions, and post evaporation of water. With the collection of oil aerosols on fibres wetted with water, a predominance of the barrel shaped droplet on the fibre was observed, with oil droplets displacing water droplets (if the oil and fibre combination created a barrel shaped droplet), creating various compound droplets of oil and water not previously reported in literature. (4) An extensive experimental investigation of the wetting processes of fibre/liquid systems during air filtration (when drag and gravitational forces are acting) has shown many important features, including droplet extension, oscillatory motion, and detachment from fibres as airflow velocity increases. The droplet oscillation is believed to be induced by the onset of the transition from laminar to turbulent flow as droplet size increases. To model such oscillation it was necessary to create a new conceptual model to account for the forces both inducing and preventing such oscillation. The agreement between the model and experimental results is satisfactory for both the radial and transverse oscillations.

L'amplitude du forçage radiatif direct par les aérosols dépend d'un grand nombre de facteurs, incluant entre autre leur nature chimique, leurs variations de concentrations temporelles et spatiales, et leur distribution en taille. Les grandes hétérogénéités de ces différents paramètres rendent les études de modélisation de l'impact radiatif délicates. Ces difficultés sont accentuées aux hautes latitudes, avec conditions environnementales particulières et un manque de données d'observation, alors même que les changements climatiques potentiels sont renforcés dans l'Arctique par certains effets de rétroactions, incluant par exemple les changements d'albédo résultants de la fonte des glaces polaires. Dans ce cadre, le programme EAAS (European Arctic Aerosol Study) avait pour objectif l'étude des propriétés physico-chimiques et optiques des aérosols dans l'Arctique européen afin d'en évaluer le forçage radiatif à l'échelle régionale. Cette étude s'est déroulée à Sevettijärvi (69°35' N., 28°50' E., 130 m au-dessus du niveau des mers), en Laponie finlandaise, de Juillet 1997 à Juin 1999. En vue de l'évaluation du forçage radiatif, nous nous sommes ainsi intéressés à la charge des différentes composantes de l'aérosol dans la basse troposphère en prenant en compte l'aérosol carboné (carbone suie et matière organique particulaire) afin de proposer un bilan de masse le plus précis possible. Nous avons ensuite, à des périodes clés de l'année, étudié plus en détail les distributions en taille des composantes de l'aérosol selon le type de masse d'air rencontré. Certaines espèces chimiques présentes au sein de l'aérosol étant issues de précurseurs gazeux, les échanges et les équilibres entre ces deux phases ont été étudiés. Un intérêt particulier a été porté à l'influence de la vapeur d'eau sur les distributions en taille des composantes particulaires. Enfin, nous avons introduit les propriétés optiques des aérosols et les paramètres importants pour une modélisation précise du forçage radiatif à l'échelle régionale.

<p>This thesis project describes how the retrieval of aerosol extinction and backscatter coefficients is computed from data obtained with a Raman lidar at FOI, Swedish Defense Research Agency. The theory is described, the implementation is done and problems discovered along the way are discussed. The lidar use the wavelength 355 nm and the Raman shift in nitrogen at 387 nm.</p><p>The retrieved algorithm gives extinction coefficient between 1 500 and 10 000 meters while the backscatter coefficient covers the span 800 to 15 000 meters. However there is skewness in the backscatter coefficient that needs to be further investigated. Tests indicate that the skewness comes from the way the measurements are done at FOI.</p>

This thesis examines the mechanisms of magnetic particle deposition and retention in human airways for magnetically targeted drug delivery. As this is a novel application, fundamental studies were performed to establish the necessary background knowledge for further development. Magnetic particle deposition from an aerosol in simulated airway conditions was studied using numerical and experimental models. The model results showed qualitative agreement; discrepancies were due to particle aggregation, which enhances deposition. Aerosol flow rate had a limited effect; the main factor in effective deposition was the proximity of the particle trajectories to the magnets. This spatial bias shows the importance of particle distribution in the flow as well as magnetic field geometry. These studies demonstrated the feasibility of capturing magnet particles from aerosol in airway conditions. For retention, clearance of particles due to motion of the mucus lining of the airways must be overcome. Particle retention was studied in vitro using various liquids to simulate mucus and identify relevant parameters. An ex vivo animal tissue model was used to demonstrate feasibility. Retention of 3-5 m diameter iron particles was achieved at reduced liquid/mucus viscosities. Larger (~100 m) particles were retained at normal mucus viscosities. The size dependence shows that particle aggregation after deposition is crucial for effective retention. In vitro retention experiments showed aggregate size is correlated with liquid viscosity, i.e. formation of aggregates is limited by forces opposing particle motion along the mucus layer interface. To determine these forces, particle motion on various air-liquid interfaces, chosen to simulate different mucus properties in isolation, was studied. When surfactants are present, as in the mucus layer, particle motion is limited by a velocity-dependent surface tension gradient as well as viscous drag. Pulling particles through the mucus layer into the tissue beneath was also considered as a potential retention strategy. The force required to pull particles through the mucus layer was also studied using various liquids to simulate mucus properties. In addition to the surface tension force holding the particles at the interface, hydrodynamic forces must be overcome to pull particles into or out of a liquid film such as the mucus layer.

Marine stratocumulus cloud regimes exert a strong climatic influence through their high solar reflectivity. Human-induced changes in stratocumulus clouds, attributed to an increase of the aerosol burden (indirect effects), can be significant given the cloud decks proximity to the continents; nevertheless, the magnitude and the final climatic consequences of these changes are uncertain. This thesis investigates further the interactions between aerosols, cloud microphysics, regional circulation, and radiative response in the Southeast Pacific stratocumulus cloud deck, one of the largest and most persistent cloud regimes in the planet. Specifically, three different aspects are addressed by this thesis: The importance of the synoptic atmospheric variability in controlling cloud microphysical and radiative changes, a validation analysis of satellite retrievals of cloud microphysics from MOderate Resolution Imaging Spectroradiometer (MODIS), and the quantitative assessments of cloud aerosol interactions along with their associated radiative forcing using primarily aircraft remote sensing data. Synoptic and satellite-derived cloud property variations for the Southeast Pacific region associated with changes in coastal satellite-derived cloud droplet number concentration (Nd) are analyzed through a composite technique. MAX and MIN Nd composites are defined by the top and bottom terciles of daily area-mean Nd values over the Arica Bight, the region with the largest mean oceanic Nd, for the five October months of 2001, 2005, 2006, 2007, and 2008. The MAX-Nd composite is characterized by a weaker subtropical anticyclone and weaker winds than the MIN-Nd composite. Additionally, the MAX-Nd composite clouds over the Arica Bight are thinner than the MIN-Nd composite clouds, have lower cloud tops, lower near-coastal cloud albedos, and occur below warmer and drier free tropospheres. At 85˚W, the top-of-atmosphere shortwave fluxes are significantly higher (50%) for the MAX-Nd, with thicker, lower clouds and higher cloud fractions than for the MIN-Nd. The change in Nd at this location is small, suggesting that the MAX-MIN Nd composite differences in radiative properties primarily reflects synoptic changes. The ability of MODIS level 2 retrievals to represent the cloud microphysics is assessed with in-situ measurements of droplet size distributions, collected during the VAMOS Ocean-Cloud-Atmosphere-Land Study Regional Experiment (VOCALS-REx). The MODIS cloud optical thickness (t) correlates well with the in-situ values with a positive bias (1.42). In contrast, the standard 2.1 micron-derived MODIS cloud effective radius (r_e) is found to systematically exceed the in-situ cloud-top r_e, with a mean bias of 2.08 um. Three sources of errors that could contribute to the MODIS r_e positive bias are investigated further: the spread of the cloud droplet size distribution, the presence of a separate drizzle mode, and the sensor viewing angles. The sensor zenith viewing angles were found to have little impact, while the algorithm assumption about the cloud droplet spectra and presence of a precipitation mode could affect the retrievals but not by enough to fully explain the positive MODIS r_e bias. The droplet spectra effects account for r_e offsets smaller than 0.6 um, 0.9 um, and 1.6 um for non-drizzling, light-drizzling, and heavy-drizzling clouds respectively. An explanation for the observed MODIS bias is lacking although three-dimensional radiative effects were not considered. This investigation supports earlier studies documenting a similar bias, this time using data from newer probes. MODIS r_e and t were also combined to estimate a liquid water path (LWP) and Nd. A positive bias was also apparent in LWP, and attributed to r_e. However, when selected appropriate parameters a priori, the MODIS Nd estimate was found to agree the best with the insitu aircraft observations of the four MODIS variables. Lastly, the first aerosol indirect effect (Twomey effect) is explicitly investigated with VOCALS-REx observations, collected during three daytime research flights (Nov 9, 11, and 13), utilizing an aerosol-cloud interactions metric, and defined as ACI=dln(t)/dln(Na), with Na corresponding to the accumulation mode aerosol concentration, t derived from a broadband pyranometer, and ACI binned by cloud LWP derived from a millimeter-wavelength radiometer. Aircraft remote sensing estimates of the ACI, during sub-cloud transects, show that the cloud aerosol-interactions are strong and close to the maximum theoretical value for thin clouds, with a decrease of ACI with LWP. Although an explanation for the dependence of ACI on LWP is lacking, we found that a decrease in ACI with LWP is associated with decreases in both surface meridional winds and Nd. Similar to ACI, albedo fractional changes due to Nd fractional changes also tended to be smaller for higher LWPs, but with an overall radiative forcing larger than conservative global estimates obtained in global circulation models. The findings of this thesis emphasize the strong stratocumulus albedo response to an aerosol perturbation and its dependence on the regional scale atmospheric configuration. The results presented here can be used as a benchmark for testing regional and climate models, as well as helping to improve the current parameterizations of the first aerosol indirect effect.

The ill-posed problem of aerosol distribution determination from a small number of backscatter and extinction lidar measurements was solved successfully via a hybrid method by a variable dimension of projection with B-Splines. Numerical simulation results with noisy data at different measurement situations show that it is possible to derive a reconstruction of the aerosol distribution only with 4 measurements.