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The making of insulin in health and diseaseVasiljevic, Jovana, Torkko, Juha M., Knoch, Klaus-Peter, Solimena, Michele 20 January 2021 (has links)
The discovery of insulin in 1921 has been one of greatest scientific achievements of the 20th century. Since then, the availability of insulin has shifted the focus of diabetes treatment from trying to keep patients alive to saving and improving the life of millions. Throughout this time, basic and clinical research has advanced our understanding of insulin synthesis and action, both in healthy and pathological conditions. Yet, multiple aspects of insulin production remain unknown. In this review, we focus on the most recent findings on insulin synthesis, highlighting their relevance in diabetes.
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Molecular mechanism of Inhibition of the CREB-coactivator TORC by the mitogen-activated kinase DLK in pancreatic beta-cellsDo, Thanh Phu 21 July 2010 (has links)
No description available.
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Electrophysiological characterization of insulin secreting beta-cells in pancreatic tissue slices / Elektrophysiologische Charakterisierung Insulin sezernierender beta-Zellen in Gewebeschnitten des PankreasSpeier, Stephan 05 November 2004 (has links)
No description available.
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