Bibliography: p. 64. / Contract no. DA36-039-AMC-03200(E).

This study provides a biological perspective on the potential of using year-round sanctuaries to protect largemouth bass (Micropterus salmoides). Although the Rideau Lakes bass sanctuaries have been present for more than 70 years, a lack of empirical rationale has resulted in a considerable debate regarding their usefulness. Using radio telemetry in Lake Opinicon, Ontario, the current study indicates that largemouth bass behaviour is influenced by the structural complexity of the habitats they occupy. In high-structure habitats, bass tend to have smaller utilization areas, displacement rates and radial displacements relative to those occupying low-structure habitats. All largemouth bass were captured and released (after transmitter implantation) in high-structure areas; however, more than half (12 of 23) of these individuals made spring (closed fishing season) relocations to low-structure areas where most (11 of 12) remained for the duration of the study. Behaviour is important to consider because of the influence it has on the level of sanctuary protection received by a largemouth bass. Twelve individuals began the study in the high-structure habitats of Lake Opinicon’s Murphy Bay fish sanctuary; however, only five remained in high-structure habitats throughout the study to receive full open season protection, two others received partial protection and four largemouth bass received no open season sanctuary protection because they made spring relocations to low-structure areas outside of the sanctuary. The results of this study provide an important biological perspective for the evaluation of year-round bass sanctuaries. Further research is needed to understand the specific causes of observed behaviours and to investigate how open and closed season protection of a year-round sanctuary translates into overall bass fishery benefits. Therefore, we recommend the maintenance of the Rideau Lakes bass sanctuaries as year-round regulations until there is sufficient empirical evidence to support their re-designation or removal. / Thesis (Master, Biology) -- Queen's University, 2010-04-01 01:39:20.969

<p>This thesis examines the bandwidth shortcomings of conventional inductive coupling biotelemetry systems for implantable devices, and presents two approaches toward an end-to-end biotelemetry system for reducing the power consumption of implanted devices at increased levels of bandwidth. By leveraging the transition zone between the near and far field, scattering in the near field at UHF frequencies for increased bandwidth at low power budgets can be employed. Additionally, taking advantage of surface wave propagation permits the use of single-wire RF transmission lines in biological tissue, offering more efficient signal routing over near field coupling resulting in controlled implant depth at low power budgets.</p><p>Due to the dielectric properties of biological tissue, and the necessity to operate in the radiating near field to communicate via scattered fields, the implant depth drives the carrier frequency. The information bandwidth supplied by each sensing electrode in conventional implants also drives the operating frequency and regime. At typical implant depths, frequencies in the UHF range permit operation in the radiating near field as well as sufficient bandwidth.</p><p>Backscatter modulation provides a low-power, high-bandwidth alternative to conventional low frequency inductive coupling. A prototype active implantable device presented in this thesis is capable of transmitting data at 30 Mbps over a 915 MHz link while immersed in saline, at a communication efficiency of 16.4 pJ/bit. A prototype passive device presented in this thesis is capable of operating battery-free, fully immersed in saline, while transmitting data at 5 Mbps and consuming 1.23 mW. This prototype accurately demodulates neural data while immersed in saline at a distance of 2 cm. This communication distance is extended at similar power budgets by exploiting surface wave propagation along a single-wire transmission line. Theoretical models of single-wire RF transmission lines embedded in high permittivity and conductivity dielectrics are validated by measurements. A single-wire transmission line of radius 152.4 um exhibits a loss of 1 dB/cm at 915 MHz in saline, and extends the implant depth to 6 cm while staying within SAR limits.</p><p>This work opens the door for implantable biotelemetry systems to handle the vast amount of data generated by modern sensing devices, potentially offering new insight into neurological diseases, and may aid in the development of BMI's.</p> / Dissertation

Para realizar medições de parâmetros fisiológicos que precisem ser determinados de maneira invasiva, técnicas de biotelemetria envolvendo unidades sensoras implantáveis passivas mostram-se bastante úteis, pois permitem sua monitoração por longos períodos. Neste trabalho é apresentado o desenvolvimento de uma nova técnica de biotelemetria que concentra qualidades desejáveis neste tipo de monitoração, tais como ausência de baterias e número mínimo de componentes eletrônicos na unidade sensora, que é formada apenas pelo próprio transdutor indutivo. Tanto a modelagem teórica do sistema quanto a especificação prática de seus componentes para realização de experimentos para sua validação são apresentadas e discutidas, resultando em um conjunto de condições a serem respeitadas e em um método de 15 passos para realização de medições. A fase da impedância de um circuito ressonante de leitura acoplado magneticamente à unidade sensora é utilizada para determinar o parâmetro de interesse. Modelos matemáticos do comportamento do circuito são apresentados detalhadamente, considerando diferentes aspectos existentes em aplicações práticas, tais como capacitâncias parasitas em bobinas e variações de indutância devidas à distância de acoplamento entre a unidade de leitura e o transdutor. A especificação de diferentes condições de contorno, necessárias para obtenção de modelos matemáticos aplicáveis, é também apresentada neste trabalho. Os resultados obtidos, tanto teóricos como experimentais, apontam para a viabilidade da proposta, e erros relativos menores do que 5 % foram obtidos na medição de indutâncias remotas com distâncias de acoplamento de até 10 mm. Além de sugestões para a continuidade do desenvolvimento da pesquisa, objetivando uma aplicação envolvendo uma unidade sensora de pequenas dimensões, neste trabalho é ainda apresentado o desenvolvimento de um sensor para medição remota de pressão, sendo que neste caso os resultados obtidos mostraram erros menores que 15 %. Os resultados obtidos neste trabalho mostram que unidades sensoras para fins biotelemétricos podem ser obtidas com construções simples compostas por apenas por um componente, oferecendo assim uma nova alternativa para monitoração de diferentes parâmetros fisiológicos. / Biotelemetry techniques with passive implantable sensing units are very useful to monitor physiological parameters that must be invasively measured, once they are able to remain inside the observed patient for long periods. This work describes the development of a new biotelemetry technique, which offers desirable characteristics in this kind of application, such as batteryless sensing unit and a minimal number of electronic components on it: only an inductive transducer itself. Besides theoretical modelling, also practical specifications of components for the validation of the system are presented and discussed, resulting in a set of conditions that must be fulfilled and in a 15 step method to perform measurements. Impedance phase measurements of a resonant reading circuit, which is magnetically coupled to the senor unit, are used to obtain the value of the target parameter. Mathematical models of circuit behaviour are presented in details, considering different aspects of practical applications, like parasitic capacitances in coils or inductance changes due to the variation of the distance between the reading unit and the sensor. Also the definition of different boundary values to the mathematical models is presented in this work. Theoretical and experimental results point to the viability of the suggested technique, and remote inductances could be measured with more than 95 % accuracy, when separated by 10 mm from the reading unit. Apart from suggestions for further developments with focus on the application of the presented technique with a small dimensions sensing unit, this work also describes the development of an inductive sensor to monitor pressure remotely and the obtained experimental results, with measurement errors below 15 %. Results from this work indicate that sensor units for biotelemetry applications can be build in a simple way, made of a single component, offering thus a new alternative to monitor different physiological parameters. Biotelemetrische Techniken, die mit implantierbaren Sensoren arbeiten, sind nürtzlich bei der invasiven Evaluierung von physiologischen Parametern, da der zu beobachtende Patient für längere Zeit die Implantate in sich behalten kann. Die Entwicklung einer neuen Technik für Biotelemetrie wird in dieser Arbeit dargestellt. Diese Technik erfüllt einige der gewünschten Bedingungen für diese Art von Anwendung und ermöglicht die Nutzung eines Sensors ohne Batterien, gebaut aus einem einzigen elektronischen Element, welches der induktivische Transduktor selber ist. Neben der theoretischen Modellierung, werden auch praktischen Angaben bezüglich der Komponenten für die Evaluierung der vorgeschlagenen Technik präsentiert und diskutiert. Daraus wird eine Gruppe von Bedingungen, die beachtet werden müssen, als auch eine aus 15 Schritten bestehende Methode für die Durchführung einer Messung abgeleitet. Es werden Phasenwinkelwerte von der Impedanz eines externen zu dem Sensor magnetisch gekuppelten Schaltkreis verwendet, um die gewünschten Parameter zu messen. Es werden ausführliche Mathematische Modelle zum Verhalten des Schaltkreises präsentiert. Dabei werden unterschiedliche Aspekte von praktischen Anwendungen, wie zum Beispiel parasitäre Kapazitäten innerhalb von Spulen und induktanzänderungen aufgrund des Kupplungsabstandes zwischen der Leseeinheit und den Transduktor, betrachtet. Die Bestimmung verschiedene Randbedingungen, notwendig für den Erhalt anwendbare mathematische Modelle, werden in dieser Arbeit ebenfalls präsentiert. Sowohl theoretische als auch praktische Ergebnisse deuten auf die Funktionstüchtigkeit der Technik hin, und Induktivitäten, die sich 10mm von der leseeinheit entfernt befanden, konnten mit mehr als 95% Genauigkeit gemessen werden. Die Arbeit enthält einige Vorschläge für die Entwicklung neuer Anwendungen mit der hier vorgestellten Technik, mit Hinsicht auf Sensoren mit kleinen Dimensionen. Die Entwicklung eines induktivischen Sensors, welcher für die ferne Messung von Druck geeignet ist, wird in der Arbeit dargestellt. Mit dem Sensor wurden Messfehler von weniger als 15% bei der Mesung von Luftdruck erreicht. Die mit dieser Arbeit gewonnenen Erkenntnisse deuten auf eine Möglichkeit der Nutzung einfacher Sensoren, bestehend aus nur Baustein, in der Biotelemetrie. Hiermit wird eine neue Alternative für die Messung unterschiedlicher physiologischer Parameter vorgestellt.

京都大学 / 0048 / 新制・課程博士 / 博士(情報学) / 甲第21394号 / 情博第680号 / 新制||情||117(附属図書館) / 京都大学大学院情報学研究科社会情報学専攻 / (主査)准教授 三田村 啓理, 教授 守屋 和幸, 教授 畑山 満則 / 学位規則第4条第1項該当 / Doctor of Informatics / Kyoto University / DFAM

No description available.

Elasmobranchs play ecologically important roles in coastal environments. Unfortunately, the basic distribution and movement patterns of these species, particularly rays, remain relatively unknown. This is especially true for the Whitespotted Eagle Ray (Aetobatus narinari), a protected species in Florida with poorly described migratory and habitat use patterns. I employed a combination of acoustic telemetry techniques to reveal multi-scale spatial patterns of A. narinari around Florida. Movement patterns between the east and west coast individuals were distinct; a majority of west coast tagged A. narinari exhibited migratory or transient behavior while most east coast tagged individuals remained resident in the Indian River Lagoon. Fine-scale tracking of A. narinari revealed individuals spent a large percentage of time in the inlets and channels and frequently reused habitats parallel to the shore. This study fills a knowledge gap on the species ecology which may be used for adaptive management strategies throughout A. narinari’s range. / Includes bibliography. / Thesis (M.S.)--Florida Atlantic University, 2018. / FAU Electronic Theses and Dissertations Collection

O desenvolvimento da Física tem possibilitado sua atuação em vários campos, e mais recentemente, na Medicina, onde estudos da Freqüência Cardíaca e do Ritmo Respiratório fornecem informações importantes acerca de processos fisiológicos e podem ser um útil instrumento diagnóstico e terapêutico. Nestes estudos, em muitos casos, necessita-se que as variáveis sejam monitoradas telemétricamente, como a observação de atletas e pacientes pré e pós-enfartados durante a prática desportiva, e estudos de animais em seu habitat natural. Desenvolvemos, portanto, um protótipo capaz de medí-las por métodos não invasivos (métodos que dispensam urna exposição cirúrgica), baseando-se na aplicação do Efeito Doppler Ultrasônico e no Movimento Mecânico do Tórax. Este protótipo consta de um conjunto de transmissores e receptores que captam e Freqüência Cardíaca e o Ritmo Respiratório, registrando de forma audível, gráfica e numérica, conforme tempos pré-estabelecidos. / The development of physics made action in various fields possible, and more recently, in Medicine, studies of heart frequency and breathing rhythm give important information about physiological status and are useful for diagnostics and therapeutics. In these studies, in many cases, it is necessary that variables could be monitored by telemetry, as p.e. observation of athletes and also before and post-glutted patients during sport practices, and studies of animals in their own habitat. We are developing, therefore, a telemetric prototype which is capable of measuring them by non-invasive methods (methods that exempt a surgical exposure), based upon application of the Ultrasonic Doppler effect and of the Mechanical Movement of thorax. This prototype consist of a group of transmitters and receivers which are getting heart beat frequency and breathing rhythm recorded by such forms: audible, graphic and numerical, in before established periods.

Resumo: A cetamina, um anestésico dissociativo, é amplamente empregado para a indução e manutenção da anestesia em cães. Possui dois enantinômeros, sendo o S(+), de atividade anestésica superior. Com este estudo objetivou-se correlacionar os parâmetros clínicos com os aspectos farmacocinéticos da cetamina S(+), bem como avaliar, o método de HPLC para quantificação deste fármaco e, as alterações farmacodinâmicas e farmacoinéticas observadas na associação deste com o midazolam. Para tanto, a cetamina S(+) foi administrada em oito cães, sendo quatro fêmeas da raça Beagle e quatro machos sem raça definida, pela via intravenosa na dose de 10mg/kg, associada ou não ao midazolam (0,2mg/kg), em duas fases distintas. A análise farmacocinética foi realizada através da cromatografia líquida de alta performance (HPLC) em amostras plasmáticas de quatros fêmeas e um macho. Os parâmetros clínicos foram obtidos por meio da biotelemetria nas quatro fêmeas e, semiotecnicamente, nos quatro machos, por um período de 12 horas. Observouse que a concentração máxima, cinco minutos após a aplicação, foi de 35,1 e 18,7 æg/mL, a meia vida de distribuição de 0,142 e 0,234 horas, a meia vida de eliminação de 3,70 e 4,06 horas, o clearance de 2,40 e 4,36 L/kg.h e o volume de distribuição de 9,70 e 16,47 L/kg, para a cetamina S(+) isolada e associada ao midazolam, respectivamente. Não foram detectadas diferenças estatísticas para os parâmetros farmacocinéticos analisados, porém foram detectadas em 15 alguns momentos para os parâmetros clínicos. Pode-se concluir que a presença do midazolam não altera os parâmetros clínicos e farmacocinéticos da cetamina S(+) em cães e, que a biodisponibilidade foi coincidente com as alterações clínicas monitoradas por meio da biotelemetria. / Abstract: Ketamine, a dissociative anesthetic agent, is widely used for induction and maintenance of anesthesia in dogs. It has two enantiomers, from which the S(+) has a greater anesthetic activity. The aim of this study was to correlate clinical parameters with pharmacokinetics aspects of ketamine S(+) as well as evaluating, the HPLC method for quantification this drug and, observed the pharmacodinamics and pharmacokinetics alterations in the association of this drug with midazolam it. For this, the ketamine was administered intravenously in eight dogs (four females beagles and four crossbreed males) at a dose of 10mg/kg, associated of not to midazolam (0.2mg/kg), in two distinct phases. Pharmacokinetic analysis was accomplished through High Performance Liquid Chromatography (HPLC) in serum samples of four females and a male. Clinical parameters were obtained through biotelemetry in the four females and semiotecnically in the four males, for 12 hour period. It was noticed that five mintues after the administration the maximum concentration was 35.1 and 18.7 æg/mL, Half-life of distribution was 0.142 and 0.234 hours, and half life of elimination was 3.7 and 4.06 hours, clearance was 2.40 and 4.36 L/kg.h and the volume of distribution was 9.70 and 16.47 L/kg, for ketamine S(+) isolated and associated to midazolam, respectively. No statistical difference was noticed in 17 the pharmacokinetic parameters, however there were differences in clinical parameters in some periods. In conclusion, the presence of midazolam does not alter clinical and pharmacokinetics parameters of ketamine S(+) in dogs and the biodisponibility of the drug was in accordance with clinical alterations monitored through biotelemetry. / Orientador: Carlos Augusto Araújo Valadão / Coorientador: Rosangela Zacarias Machado / Banca: Newton Nunes / Banca: José Francisco Fracasso / Mestre

Made available in DSpace on 2014-06-11T19:23:42Z (GMT). No. of bitstreams: 0 Previous issue date: 2007-08-10Bitstream added on 2014-06-13T20:11:24Z : No. of bitstreams: 1 galhardo_a_me_jabo.pdf: 395101 bytes, checksum: e772cc6cb2c6cd3e0d11abdb749af7ff (MD5) / Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) / A cetamina, um anestésico dissociativo, é amplamente empregado para a indução e manutenção da anestesia em cães. Possui dois enantinômeros, sendo o S(+), de atividade anestésica superior. Com este estudo objetivou-se correlacionar os parâmetros clínicos com os aspectos farmacocinéticos da cetamina S(+), bem como avaliar, o método de HPLC para quantificação deste fármaco e, as alterações farmacodinâmicas e farmacoinéticas observadas na associação deste com o midazolam. Para tanto, a cetamina S(+) foi administrada em oito cães, sendo quatro fêmeas da raça Beagle e quatro machos sem raça definida, pela via intravenosa na dose de 10mg/kg, associada ou não ao midazolam (0,2mg/kg), em duas fases distintas. A análise farmacocinética foi realizada através da cromatografia líquida de alta performance (HPLC) em amostras plasmáticas de quatros fêmeas e um macho. Os parâmetros clínicos foram obtidos por meio da biotelemetria nas quatro fêmeas e, semiotecnicamente, nos quatro machos, por um período de 12 horas. Observouse que a concentração máxima, cinco minutos após a aplicação, foi de 35,1 e 18,7 æg/mL, a meia vida de distribuição de 0,142 e 0,234 horas, a meia vida de eliminação de 3,70 e 4,06 horas, o clearance de 2,40 e 4,36 L/kg.h e o volume de distribuição de 9,70 e 16,47 L/kg, para a cetamina S(+) isolada e associada ao midazolam, respectivamente. Não foram detectadas diferenças estatísticas para os parâmetros farmacocinéticos analisados, porém foram detectadas em 15 alguns momentos para os parâmetros clínicos. Pode-se concluir que a presença do midazolam não altera os parâmetros clínicos e farmacocinéticos da cetamina S(+) em cães e, que a biodisponibilidade foi coincidente com as alterações clínicas monitoradas por meio da biotelemetria. / Ketamine, a dissociative anesthetic agent, is widely used for induction and maintenance of anesthesia in dogs. It has two enantiomers, from which the S(+) has a greater anesthetic activity. The aim of this study was to correlate clinical parameters with pharmacokinetics aspects of ketamine S(+) as well as evaluating, the HPLC method for quantification this drug and, observed the pharmacodinamics and pharmacokinetics alterations in the association of this drug with midazolam it. For this, the ketamine was administered intravenously in eight dogs (four females beagles and four crossbreed males) at a dose of 10mg/kg, associated of not to midazolam (0.2mg/kg), in two distinct phases. Pharmacokinetic analysis was accomplished through High Performance Liquid Chromatography (HPLC) in serum samples of four females and a male. Clinical parameters were obtained through biotelemetry in the four females and semiotecnically in the four males, for 12 hour period. It was noticed that five mintues after the administration the maximum concentration was 35.1 and 18.7 æg/mL, Half-life of distribution was 0.142 and 0.234 hours, and half life of elimination was 3.7 and 4.06 hours, clearance was 2.40 and 4.36 L/kg.h and the volume of distribution was 9.70 and 16.47 L/kg, for ketamine S(+) isolated and associated to midazolam, respectively. No statistical difference was noticed in 17 the pharmacokinetic parameters, however there were differences in clinical parameters in some periods. In conclusion, the presence of midazolam does not alter clinical and pharmacokinetics parameters of ketamine S(+) in dogs and the biodisponibility of the drug was in accordance with clinical alterations monitored through biotelemetry.