Made available in DSpace on 2016-01-26T18:55:27Z (GMT). No. of bitstreams: 1 Dissertacao Camila.pdf: 356742 bytes, checksum: d31eb9f6798556536fdad46d8eb56d72 (MD5) Previous issue date: 2008-08-27 / This study compared the analgesic, sedative and neuroendocrine effects of the epidural (EP) and intramuscular (IM) methadone in cats submitted to ovariohisterectomy. Cats were randomly assigned to three groups of 08 animals each and received EP or IM methadone (0.2mg.kg-1 diluted with saline to 0.2ml.kg-1, G1 and G2, respectively) or a saline placebo (G3). Pre-anaesthetic medication was acepromazine (0.1mg.kg-1 IM). Anaesthesia was induced with thiopental (12mg.kg-1 IV) and maintained with halothane. Serum cortisol concentration, behavioral changes, degree of analgesia and sedation were evaluated. In the epidural methadone group (G1) lower scores of pain were observed when compared with the others groups, but the difference did not significance. Rescue analgesia was administered 3 times to 02 cats in the G1, 9 times to 05 cats in the G2 and 11 times to 06 cats in the G3. It was concluded that the methadone preemptive administration reduced postoperative analgesic requirement. Stress response was modulated by methadone in cats submitted to ovariohisterectomy. / Esse estudo comparou os efeitos analgésicos, sedativos e neuroendócrinos do opióide metadona administrado via intramuscular ou epidural em gatas, submetidas a ovariossalpingohisterectomia (OSH). Os animais foram distribuídos aleatoriamente em três grupos de 08 animais cada, sendo tratados com metadona pela via epidural ou intramuscular (0,2mg.kg-1 diluída em solução salina em volume final de 0.2ml.kg-1, G1 e G2, respectivamente) ou com solução salina (G3) (n=8). Na medicação pré-anestésica foi administrada acepromazina (0,1mg.kg-1 IM), a indução anestésica foi realizada com tiopental sódico (12mg.kg-1 IV), com posterior manutenção em anestesia geral inalatória, com halotano. Avaliaram-se comportamento, grau de analgesia, sedação e concentração sérica de cortisol. No grupo tratado com metadona epidural (G1), foram observados escores inferiores de dor, quando comparados aos demais grupos. Analgesia resgate foi administrada 3 vezes em 2 animais do G1, 9 vezes em 5 animais do G2 e 11 vezes em 6 animais do G3. Conclui-se que a administração preemptiva da metadona reduziu o requerimento de analgésico pós-operatório. Paralelamente, a metadona favoreceu a modulação da resposta de estresse em gatas submetidas à OSH.

Made available in DSpace on 2016-01-26T18:55:36Z (GMT). No. of bitstreams: 1 Paulo Henrique da Silva.pdf: 146595 bytes, checksum: b33ac213ba3a976522fc7a41aa05e514 (MD5) Previous issue date: 2013-08-05 / Changes in the results of erythrocyte standards require decisions and guide the conduct of clinical regarding prognosis and treatment of any diseases. The use of modern equipment that make the blood cell count used to calculate the RDW (red cell distribution width) and its fractions RDW-CV and RDW-SD, which provide a quantitative assessment of heterogeneity of each erythrocyte. Given the limited information available in the literature about the RDW for the domestic cat, this study aims to compare the values of RDW, with MCV and reticulocytes from 40 (n=14males, n=26 females) healthy mongrel cats, with age ranging from 1.2 to 5.5 years (3.0 ± 1.2) were used. The animals were kept in individual cages all over the experiment. Blood samples were taken directly from the external jugular vein and separated into two tubes: one containing anticoagulant EDTA (ethylene diamine tetra acetic acid) to 10% for the complete blood count and the second without anticoagulant for biochemical tests. The results showed that there is a direct relationship between values of RDW-SD and RDW-CV and an inverse correlation between RDW-CV with MCV. There was no relation between RDW and reticulocyte aggregates or punctate. There was no relation between sex and RDW as well. RDW values determined in this experiment can be used as a resource for future research and also as reference values for the feline species. / As alterações nos resultados dos padrões eritrocitários demandam decisões e norteiam a conduta do clínico quanto ao prognóstico e a terapêutica de eventuais patologias. A utilização de equipamentos modernos que fazem a contagem celular sanguínea permite calcular a amplitude de distribuição dos eritrócitos ou RDW (red cell distribution width) e suas frações RDW-CV e RDW-SD, que provêem uma avaliação quantitativa da heterogenicidade de cada eritrócito. Diante da escassa informação disponível na literatura científica sobre os valores de RDW para o gato doméstico, este estudo se propõe a comparar os valores de RDW com o VCM e reticulócitos de 40 gatos domésticos hígidos, sem raça definida, com idade variando de 1,2 a 5,5 anos (3,0±1,2), sendo 14 machos e 26 fêmeas provenientes do gatil da instituição. O sangue foi colhido diretamente da veia jugular externa e separado em dois tubos: um contendo anticoagulante EDTA (ácido etileno diamino tetra acético) a 10%, para a realização do hemograma e o segundo, sem anticoagulante, para as provas bioquímicas de triagem. Os resultados encontrados mostraram que existe uma relação direta significativa entre os valores de RDW-SD e RDW-CV e uma correlação inversa entre os valores de RDW-CV o VCM. Não houve correlação entre os valores de RDW e reticulócitos agregados ou ponteados. O sexo não interfere no diâmetro das hemácias. Os valores de RDW determinados neste experimento podem ser usados como fonte de consulta para futuras pesquisas e também como valores de referência da espécie felina.

Made available in DSpace on 2016-01-26T18:55:45Z (GMT). No. of bitstreams: 1 Dissertacao Cleidemar.pdf: 291699 bytes, checksum: 46535cd36bde0f3bcd3e5d22ca0f3899 (MD5) Previous issue date: 2008-03-28 / The objective was to validate a sensitive, single, rapid and low cost analytical method is presented for determination of amitraz concentration in cat plasma samples using gas chromatography with capillary column and thermionic specific detector (GC-TSD). The method was linear between 20 to 400 ng ml-1 with regression coefficients corresponding to 0.9987 and the coefficient of variation of the points of the calibration curve lower than 20%. The detection limits and quantification were 10 and 20 ng ml-1 respectively. The proposed method was useful and efficient for detection of the amitraz in the plasma of cats intoxicated with this product in a dipping bath. / O objetivo foi validar um método analítico simples, rápido e de baixo custo para determinação da concentração de amitraz no plasma de gatos intoxicados experimentalmente através de banho, empregando-se a cromatografia gasosa com coluna capilar e detector termiônico específico (CG-DTE). O método mostrou-se linear na faixa entre 20 a 400 ng/mL com coeficiente de correlação igual a 0,9987 e o coeficiente de variação dos pontos da curva de calibração abaixo de 15%. Os limites de detecção e quantificação foram 10 ng/mL e 20 ng/mL respectivamente. A metodologia empregada se mostrou útil e eficiente para detecção do amitraz no plasma de gatos intoxicados com este produto.

Made available in DSpace on 2016-07-18T17:53:05Z (GMT). No. of bitstreams: 1 Dissertacao Camila.pdf: 356742 bytes, checksum: d31eb9f6798556536fdad46d8eb56d72 (MD5) Previous issue date: 2008-08-27 / This study compared the analgesic, sedative and neuroendocrine effects of the epidural (EP) and intramuscular (IM) methadone in cats submitted to ovariohisterectomy. Cats were randomly assigned to three groups of 08 animals each and received EP or IM methadone (0.2mg.kg-1 diluted with saline to 0.2ml.kg-1, G1 and G2, respectively) or a saline placebo (G3). Pre-anaesthetic medication was acepromazine (0.1mg.kg-1 IM). Anaesthesia was induced with thiopental (12mg.kg-1 IV) and maintained with halothane. Serum cortisol concentration, behavioral changes, degree of analgesia and sedation were evaluated. In the epidural methadone group (G1) lower scores of pain were observed when compared with the others groups, but the difference did not significance. Rescue analgesia was administered 3 times to 02 cats in the G1, 9 times to 05 cats in the G2 and 11 times to 06 cats in the G3. It was concluded that the methadone preemptive administration reduced postoperative analgesic requirement. Stress response was modulated by methadone in cats submitted to ovariohisterectomy. / Esse estudo comparou os efeitos analgésicos, sedativos e neuroendócrinos do opióide metadona administrado via intramuscular ou epidural em gatas, submetidas a ovariossalpingohisterectomia (OSH). Os animais foram distribuídos aleatoriamente em três grupos de 08 animais cada, sendo tratados com metadona pela via epidural ou intramuscular (0,2mg.kg-1 diluída em solução salina em volume final de 0.2ml.kg-1, G1 e G2, respectivamente) ou com solução salina (G3) (n=8). Na medicação pré-anestésica foi administrada acepromazina (0,1mg.kg-1 IM), a indução anestésica foi realizada com tiopental sódico (12mg.kg-1 IV), com posterior manutenção em anestesia geral inalatória, com halotano. Avaliaram-se comportamento, grau de analgesia, sedação e concentração sérica de cortisol. No grupo tratado com metadona epidural (G1), foram observados escores inferiores de dor, quando comparados aos demais grupos. Analgesia resgate foi administrada 3 vezes em 2 animais do G1, 9 vezes em 5 animais do G2 e 11 vezes em 6 animais do G3. Conclui-se que a administração preemptiva da metadona reduziu o requerimento de analgésico pós-operatório. Paralelamente, a metadona favoreceu a modulação da resposta de estresse em gatas submetidas à OSH.

Made available in DSpace on 2016-07-18T17:53:11Z (GMT). No. of bitstreams: 1 Paulo Henrique da Silva.pdf: 146595 bytes, checksum: b33ac213ba3a976522fc7a41aa05e514 (MD5) Previous issue date: 2013-08-05 / Changes in the results of erythrocyte standards require decisions and guide the conduct of clinical regarding prognosis and treatment of any diseases. The use of modern equipment that make the blood cell count used to calculate the RDW (red cell distribution width) and its fractions RDW-CV and RDW-SD, which provide a quantitative assessment of heterogeneity of each erythrocyte. Given the limited information available in the literature about the RDW for the domestic cat, this study aims to compare the values of RDW, with MCV and reticulocytes from 40 (n=14males, n=26 females) healthy mongrel cats, with age ranging from 1.2 to 5.5 years (3.0 ± 1.2) were used. The animals were kept in individual cages all over the experiment. Blood samples were taken directly from the external jugular vein and separated into two tubes: one containing anticoagulant EDTA (ethylene diamine tetra acetic acid) to 10% for the complete blood count and the second without anticoagulant for biochemical tests. The results showed that there is a direct relationship between values of RDW-SD and RDW-CV and an inverse correlation between RDW-CV with MCV. There was no relation between RDW and reticulocyte aggregates or punctate. There was no relation between sex and RDW as well. RDW values determined in this experiment can be used as a resource for future research and also as reference values for the feline species. / As alterações nos resultados dos padrões eritrocitários demandam decisões e norteiam a conduta do clínico quanto ao prognóstico e a terapêutica de eventuais patologias. A utilização de equipamentos modernos que fazem a contagem celular sanguínea permite calcular a amplitude de distribuição dos eritrócitos ou RDW (red cell distribution width) e suas frações RDW-CV e RDW-SD, que provêem uma avaliação quantitativa da heterogenicidade de cada eritrócito. Diante da escassa informação disponível na literatura científica sobre os valores de RDW para o gato doméstico, este estudo se propõe a comparar os valores de RDW com o VCM e reticulócitos de 40 gatos domésticos hígidos, sem raça definida, com idade variando de 1,2 a 5,5 anos (3,0±1,2), sendo 14 machos e 26 fêmeas provenientes do gatil da instituição. O sangue foi colhido diretamente da veia jugular externa e separado em dois tubos: um contendo anticoagulante EDTA (ácido etileno diamino tetra acético) a 10%, para a realização do hemograma e o segundo, sem anticoagulante, para as provas bioquímicas de triagem. Os resultados encontrados mostraram que existe uma relação direta significativa entre os valores de RDW-SD e RDW-CV e uma correlação inversa entre os valores de RDW-CV o VCM. Não houve correlação entre os valores de RDW e reticulócitos agregados ou ponteados. O sexo não interfere no diâmetro das hemácias. Os valores de RDW determinados neste experimento podem ser usados como fonte de consulta para futuras pesquisas e também como valores de referência da espécie felina.

Made available in DSpace on 2016-07-18T17:53:18Z (GMT). No. of bitstreams: 1 Dissertacao Cleidemar.pdf: 291699 bytes, checksum: 46535cd36bde0f3bcd3e5d22ca0f3899 (MD5) Previous issue date: 2008-03-28 / The objective was to validate a sensitive, single, rapid and low cost analytical method is presented for determination of amitraz concentration in cat plasma samples using gas chromatography with capillary column and thermionic specific detector (GC-TSD). The method was linear between 20 to 400 ng ml-1 with regression coefficients corresponding to 0.9987 and the coefficient of variation of the points of the calibration curve lower than 20%. The detection limits and quantification were 10 and 20 ng ml-1 respectively. The proposed method was useful and efficient for detection of the amitraz in the plasma of cats intoxicated with this product in a dipping bath. / O objetivo foi validar um método analítico simples, rápido e de baixo custo para determinação da concentração de amitraz no plasma de gatos intoxicados experimentalmente através de banho, empregando-se a cromatografia gasosa com coluna capilar e detector termiônico específico (CG-DTE). O método mostrou-se linear na faixa entre 20 a 400 ng/mL com coeficiente de correlação igual a 0,9987 e o coeficiente de variação dos pontos da curva de calibração abaixo de 15%. Os limites de detecção e quantificação foram 10 ng/mL e 20 ng/mL respectivamente. A metodologia empregada se mostrou útil e eficiente para detecção do amitraz no plasma de gatos intoxicados com este produto.

No description available.

Birds uniquely produce sound through a vocal organ known as a syrinx. The presence of wall shear stress acting on the airway cells of any organism will affect how airway cells develop and multiply. Unique features of avian airway geometry and breathing pattern might have contributed to the development of the syrinx. This thesis examines wall shear stress in the trachea and first bronchi of avian geometries using computational fluid dynamics. The computational fluid dynamic simulations underwent grid- and time-independence studies and were validated using particle image velocimetry. Parameters such as bird size, bronchial branching angle, and breathing waveform were examined to determine conditions that contributed to higher wall shear stress. Both simplified and CT scan-derived respiratory geometries were examined. Maximum wall shear stress for the simplified geometries was found to be highest during the inspiratory phase of breathing and was highest near the pessulus. Maximum wall shear stress in the CT scan-derived geometries was less phase-dependent and was highest near constrictions in the airway. Comparison between scanned and simplified geometry simulations revealed significant differences in wall shear stress magnitudes and flow features. If wall shear stress is found to be important in the development of the syrinx or the advantage of a syrinx, the thesis results are anticipated to aid in characterizing conditions that would have contributed to the development of the syrinx or advantages of syringeal vocal fold position over tracheal vocal fold position.

abstract: This research aims to investigate the social environment in a brand-new type of café, pet café, and to maximum the benefit of this type of cafe. While pet cafés, especially cat cafés, are becoming increasingly common in the United States (U.S.), Asian countries have been in this kind of business since 1998. The most common and popular is the cat café. Even though the owners of cat cafés in the U.S. have learned and imitated the cat café in Asia, the cultural differences and the restrictions resulted in differences in format and design. Interior and furniture design was investigated to afford motivation to people who are pet lovers and can be potential customers. Most of the research about pets illustrates a positive influence on psychological health and social support. On the other hand, a café with pets can be attractive and interactive more than a general café, to offer a recreational activity and a comfortable social environment and therapy from pets. Juxtaposing the cat café in the U.S. against the pet café in China, is explored to investigate the difference between these countries and how they can learn from each other and make improvements to design. Research on what is the difference between the cat café in the U.S. and China are reflected on two parts of outcomes—design and business. / Dissertation/Thesis / Masters Thesis Design 2019

Hierdie studie fokus op hoe persone wat van dwelms afhanklik is of was, hulle identiteit sien. Daar is ’n bekende diskoers wat sê: “Een keer ’n verslaafde, altyd ’n verslaafde.” Hierdie diskoers impliseer dat afhanklikheid deel van ’n persoon se identiteit word. In my studie poog ek om hierdie diskoers te dekonstrueer. Die AA (Alkoholiste Anoniem) se twaalf-stap-program word bestudeer. In hulle eerste stap word daar van persone wat van ’n chemiese stof afhanklik is, verwag om te erken dat hy/sy ’n afhanklike is. Hierdie erkenning van die AA se eerste stap, het ’n direkte invloed op persone wat van dwelms afhanklik is of was. Saam met die medenavorsers, word daar gepoog om ’n alternatiewe manier te vind om na afhanklikheid en identiteit te kyk. Hiermee saam speel die Christendom en ’n persoon se Godsbegrip ’n groot rol. Die Christendom het verskillende sieninge oor afhanklikheid en sonde. Hierdie studie poog nie om die sondebegrip van die Nuwe Testament te bestudeer nie, aangesien hierdie nie ’n Nuwe-Testamentiese studie is nie. Hoe God en die medenavorsers sonde verstaan, speel ’n rol in die begrip van hulle identiteit. Die narratiewe benadering maak van metafore gebruik. Hierdie studie gebruik die metafoor van ’n draak. Aanvanklik is dit ’n gevreesde draak wat persone wat afhanklik van dwelms is of was, wil verslind en ’n direkte impak het op hulle identiteit. ‘n Nuwe metafoor het ontwikkel. Die animasiefilm, “How to train your dragon,” is as vertrekpunt gebruik om ’n nuwe metafoor te ontwikkel waar die draak steeds gevaarlik is, maar getem kan word. Deur sekere aanpassings te maak, kan persone wat afhanklik is of was van dwelms, die draak beheer. Hierdie nuwe metafoor gee ook ’n nuwe identiteit aan die persoon wat afhanklik is of was van dwelms. Afhanklikheid word nie meer as deel van ’n persoon se identiteit beskou nie aangesien die hantering van die draak ’n nuwe perspektief in die lewe van hierdie persoon gee. In my studie maak ek van kwalitatiewe navorsing gebruik en beweeg ek vanuit die oogpunt van ’n postfundamentele Praktiese Teologiese benadering. / Thesis (PhD)--University of Pretoria, 2017. / Practical Theology / PhD / Unrestricted