Thesis (M.A.)--University of Hong Kong, 1989. / Also available in print.

Thesis (M.A.)--Guo li Taiwan da xue. / Cover title. Reproduced from typescript. Includes bibliographical references (p. 146-152).

Thesis (M.A.)--Guo li Taiwan da xue. / Cover title. Reproduced from typescript. Bibliography: p. 146-152.

Rock’n’roll. Ce terme s’est répandu d’abord dans le monde occidental à la fin des années 1950, principalement grâce au succès d’Elvis Presley. Fusion du blues, du rhythm’n’blues, du gospel, du doo-wop et de la country. Le terme rock’n’roll désigne à l’origine une musique nouvelle, adoptée avec enthousiasme par la jeunesse américaine rompant résolument avec la musique qu’écoutaient leurs parents. Le rock’n’roll, synonyme de révolte de la jeunesse, secoua l’Amérique à la fin des années 1950. Le 9 mai 1986, un grand concert rendant hommage à « l’Année Mondiale de la paix » a eu lieu au « Gongti » gongrentiyuguan à Pékin. Cui Jian, un jeune chanteur totalement inconnu portant une longue veste est monté sur scène en sautant. Avec sa voix étrange et son énergie communicative de jeune garçon, il a chanté une chanson composée par lui – même : «rien à mon nom». Ce fut le début de l’histoire du rock chinois, le Yaogun.Pendant les trois décennies que la Chine vient de traverser, un régime « capitaliste sauvage » s’est confortablement installé dans le pays. Ces trente dernières années ont témoigné du « spectaculaire intégré », concept défini par Guy Deobrd. Dans ce contexte, la musique Rock a fait son apparition au début des années 1980 en Chine.Cette thèse se penche sur la phénomène du rock chinois, nos recherches s’organisent autour d’un objectif commun : approcher, analyser et comprendre la situation du rock en Chine. Nous tentons de faire une étude des rapports sociaux, économiques et culturels que ce phénomène artistique reflète par son apparition, son évolution, ses difficultés et ses perspectives. / The term Rock’n’roll became firstly known in the Western society in the fifties due to the phenomenal success of Elvis Presley. A combination of blues, rhythm’n’blues, doo-wop and country music, the new genre of Rock’n’roll music has been extremely popular in the US, where it is seen as the synonym of youth and rebellion.The very first page of the Chinese rock, the “Yaogun”, was turned on May 9th 1986, when a big charity concert in the name of ‘The International Year of Peace’ took place at the famous Beijing Workers’ Stadium. During this concert, a young and unfamous musician Cui Jian performed a song written by himself, which is titled “I Have Nothing”.This thesis investigates the Yaogun phenomenon in order to achieve some understanding of the mechanisms underlying cultural dynamics in contemporary China. It situates the Chinese rock in the context of the development of “market economy" in China during the last three decades. The author applies Guy Debord’s key concept of “integrated spectacle” to illustrate and analyze the development of Chinese rock in the social, historical and political nexus.

No description available.

This thesis concerns optimal designs and estimation approaches for a class of nonlinear dose response models, namely multi-response Emax models. These models describe the relationship between the dose of a drug and two or more efficacy and/or safety variables. In order to obtain precise parameter estimates it is important to choose efficient estimation approaches and to use optimal designs to control the level of the doses administered to the patients in the study. We provide some optimal designs that are efficient for estimating the parameters, a subset of the parameters, and a function of the parameters in multi-response Emax models. The function of interest is an estimate of the best dose to administer to a group of patients. More specifically the dose that maximizes the Clinical Utility Index (CUI) which assesses the net benefit of a drug taking both effects and side-effects into account. The designs derived in this thesis are locally optimal, that is they depend upon the true parameter values. An important part of this thesis is to study how sensitive the optimal designs are to misspecification of prior parameter values. For multi-response Emax models it is possible to derive maximum likelihood (ML) estimates separately for the parameters in each dose response relation. However, ML estimation can also be carried out simultaneously for all response profiles by making use of dependencies between the profiles (system estimation). In this thesis we compare the performance of these two approaches by using a simulation study where a bivariate Emax model is fitted and by fitting a four dimensional Emax model to real dose response data. The results are that system estimation can substantially increase the precision of parameter estimates, especially when the correlation between response profiles is strong or when the study has not been designed in an efficient way. / <p>At the time of the doctoral defence the following papers were unpublished and had a status as follows: Paper 1: Manuscript; Paper 2: Manuscript; Paper 3: Manuscript; Paper 4: Manuscript.</p>

This thesis is the use of commercially available methyl 2-iodobenzoate as the starting material and was prepared into iodine - oxazoline compound 118. Then, we undergo copper-catalyzed cross-coupling reactions of compound 118with thiols, and were readily facilitated to afford the corresponding desired products 127¡B136 in good to excellent yields. This method not only modified short- comings of that adding strong base to synthesis of sulfur-oxazoline ligands in past years but also has a good yield performances, the yield is 70 -87%. And we will use this strategy to undergo one pot reaction of carbon-sulfur coupling in future. In the end, we used new sulfur-oxazoline ligands127¡B128 in the Pd-catalyzed asymmetric alkylation of 1,3-diphenyl-2-propenyl acetate with dimethyl malonate. and reaction ee% were high, with the best result of 99% and 93% conversion.

[EN] Idiopathic pulmonary fibrosis (IPF) is the pulmonary disease with higher incidence and worse prognosis. Recent evidence suggests that cucurbitaceae, selective inhibitors of the JAK2/STAT3 pathway, may improve the pathogenesis of IPF, as anti-inflammatory and antioxidative properties have been confirmed in other diseases. However the role in IPF is unknown. Two pharmacological models were investigated in the present study. In the preventive model, Wistar rats were instilled intratracheally with a single dose of bleomycin (BLM)(3.75 U/kg; n=12) to induce lung injury. CuI (20mg/kg/day; n=6) or CuI vehicle (control and IPF group) was administered intraperitoneally daily for 21 days. The therapeutic model was exactly the same starting CuI administration on day 7 until day 21. Animal evolution together with the ventilation-perfusion ratio was controlled through CT/SPECT imaging. Cellular count and characterization was performed in broncoalveolar lavage (BAL) together with the total protein content and the IL-6 and IL-13 concentration in BAL and lung tissue. Hematoxilin-eosin and masson trichrome stains allowed the study of the lung's tissue histology. TGF-ß1, CTGF, COL1A and ET-1 gene and protein expression were both measured by real time PCR and WB as pulmonary vascular remodeling markers. P-STAT3, P-SMAD3 and P-JAK2 proteins were determined by protein and immunohistochemistry quantification. Finally, JAK2 and STAT3 expression and distribution was studied in lung tissue of fibrotic patients with pulmonary hypertension. CT/SPECT quantification showed reduction of the fibrotic areas in the CuI treated group by reestablishing the air space in the lungs back to day 0 levels for the preventive and the therapeutic model. Furthermore, ventilation/perfusion correlation was restored in the therapeutic model after administrating CuI during 14 days. Hematoxilin-eosine stains demonstrated how the group treated pharmacologically presented an improvement in the lung tissue architecture, reversing vascular remodeling and right heart hypertrophy. Masson trichrome stain revealed a reduction of the collagen deposits. Ashcroft score, used to determine the severity of pulmonary fibrosis, was measured and diminished significantly in the CuI treated group. The results showed a gene and protein overexpression of TGF-ß1, CTGF, COL1A and ET-1 in BLM relative to Control rats. This was counteracted with CuI treatment which reduced the expression back to control. In terms of immunohistochemistry, the results demonstrated a decrease in the COL1A deposits in the treated group versus the absence of treatment group. Protein and immunohistochemistry analysis of JAK2, STAT3 and SMAD3 demonstrated an overexpression in bleomycin rats while the protein expression was inhibited in the CuI treated group. In accordance to the results obtained, the immunohistochemistry analysis of the lung parenchyma in patients with pulmonary hypertension related to pulmonary fibrosis showed and overexpression of the phosphorylated forms of JAK2 and STAT3, lacking its expression in healthy lung tissue. The preventive and therapeutic administration of JAK2/STAT3 inhibitor can be a potential treatment for pulmonary fibrosis, as it improves the parameters related to the disease. / [ES] La fibrosis pulmonar idiopática (FPI) es la enfermedad pulmonar con mayor incidencia y peor pronóstico. Estudios recientes sugieren que la familia de las cucurbitaceae, inhibidores selectivos de la ruta JAK2/STAT3, pueden mejorar la patogénesis de la enfermedad, al haberse confirmado sus propiedades antinflamatorias y antioxidantes en otras enfermedades. Sin embargo se desconoce su papel en FPI. En el presente trabajo se estudiaron dos modelos farmacológicos. En el modelo preventivo las ratas Wistar fueron instiladas con una dosis única de bleomicina intratraqueal (BLM)(3.75 U/kg; n=12) para inducir las lesión pulmonar. Durante 21 días se administró CuI (20mg/kg/día; n=6) o vehículo de CuI (control y grupo FPI) por vía intraperitoneal. El modelo curativo se diferencia del preventivo en el comienzo de la administración farmacológica a los 7 días de inducir la enfermedad. El seguimiento de la evolución animal y el ratio de ventilación-perfusión se realizó mediante las técnicas de imagen TC/SPECT. Se realizó el recuento y caracterización de las células totales extravasadas en lavado broncoalveolar (LBA) así como el contenido de proteína total y la concentración de IL- 6 e IL-13 en LBA y tejido pulmonar. Las tinciones de hematoxilina-eosina y masson tricrómico permitieron el estudio de la histología del tejido pulmonar. Se determinó la expresión génica y proteica de TGF-ß1, CTGF, COL1A y ET-1 mediante las técnicas de real time PCR y WB como marcadores de remodelado vascular. Las proteínas P-STAT3, P-SMAD3 y P-JAK2, fueron determinadas mediante cuantificación proteica e inmunohistoquimia. Por último se estudió la expresión y distribución de JAK2 y STAT3 en tejido de pacientes con fibrosis pulmonar e hipertensión pulmonar. La cuantificación de las imágenes TC/SPECT mostraron una reducción de las áreas fibróticas en el grupo tratado con CuI. El tratamiento farmacológico permitió el restablecimiento del espacio aéreo pulmonar hasta valores control en ambos modelos estudiados. El grupo con tratamiento farmacológico restauró el ratio de ventilación/perfusión tras administrar CuI durante 14 días. Las tinciones de hematoxilina eosina revelaron como el grupo animal tratado farmacológicamente presenta una mejora de la histología pulmonar, revirtiendo el remodelado vascular y la hipertrofia del ventrículo derecho. La tinción de masson tricrómico mostró una disminución de los depósitos de colágeno. Se determinó el valor de Ashcroft, evaluador del grado de fibrosis pulmonar, que descendió significativamente en el grupo tratado con CuI. Los resultados presentan una sobrexpresión génica y proteica de TGF-ß1, CTGF, COL1A y ET-1 en los grupos de bleomicina frente a las ratas control. Dicha condición fue revertida mediante el tratamiento con CuI que restableció los valores a niveles control. Los análisis proteicos e inmunohistoquíimicos de JAK2, STAT3 y SMAD3 revelaron una sobreexpresión en las ratas con bleomicina mientras que la expresión proteica fue inhibida en el grupo tratado con CuI. En consonancia con los resultados obtenidos, el análisis inmunohistoquímico del parénquima pulmonar de pacientes con FPI e HP asociada muestran una sobreeexpresión de las formas fosforiladas de JAK2 y STAT3 frente a la ausencia de expresión en tejido pulmonar sano. La administración curativa y preventiva de un inhibidor de la ruta JAK2/STAT3 puede ser un potencial tratamiento para la fibrosis pulmonar, ya que mejora parámetros indicativos de la patología. / [CAT] La fibrosi pulmonar idiopàtica (FPI) és la enfermetat pulmonar amb major incidència i pitjor pronostic. Estudis recents suggereixen que la família de les cucurbitàcies, Inhibidors selectius de la ruta JAK2 / STAT3, poden millorar la patogènesi de la malaltia, en haver-se confirmat les seues propietats antiinflamatòries i antioxidants En altres patologies. No obstant això es desconeix el seu paper en FPI. En el present treball es van estudiar 2 models farmacològics. En el model preventiu les rates Wistar foren instilades amb una dosi única de bleomicina intratraqueal (BLM) (3,75 U / kg; n = 12) per a induir les lesions pulmonars. Durant 21 dies es va administrar CuI (20 mg / kg / dia, n = 6) o Vehicle de CuI (control i grup FPI) per vía intraperitoneal. El model curatiu es diferència del preventiu en el començament de l'administració farmacológica als 7 dies d'induir l'enfermetat. El seguiment de l'evoluciò dels animals i el ratio de Ventilació-perfusió es va realitzar mitjançant tècniques d'imatge TC/SPECT. Es realitzà el recompte i caracterització de les cèl·lules totals extravasades en el llavat broncoalveolar (LBA). Així com el contingut de proteina total i la concentració d'IL-6 i IL-13 en LBA i teixit pulmonar. Les tincions d'hematoxilina-eosina i tricròmic de Masson van permetre l'estudi de la histologia del teixit pulmonar. Es va determinar l'expressió gènica i proteica de TGF-ß1, CTGF, COL1A i Et-1 mitjançant tècniques de PCR en temps real i WB com marcadors de remodelat vascular. Les proteïnes P-STAT3, P-SMAD3 i P-JAK2, varen ser determinades mitjançant quantificació proteica i inmunohistoquimia. Per últim se estudià l'expressió i distribució de JAK2 i STAT3 en teixit de pacients amb fibrosi pulmonar e hipertensió pulmonar. La quantificació de les imatges TC/SPECT mostraren una reducció de les àrees fibrótiques en el grup tractat amb CuI. El tractament farmacològic permet el restabliment de l'espai aeri pulmonar fins valors de control en els dos models estudiats. El grup amb tractament farmacològic va restaurar el ratio de ventilació/perfusió tras administrar Cul durant 14 dies. Les tincions d'hematoxilina eosina van revelar com el grup animal tractat farmacològicament presenta una Millora de la histologia pulmonar, revertint el remodelat vascular i la hipertròfia del ventricle dret. La tinció de tricròmic de Masson va mostrar una disminució dels dipòsits de col·lagen. Es va determinar el valor d'Ashcroft, avaluador del grau de fibrosi pulmonar, que va baixar significativament a el grup tractat amb CuI. Els resultats presenten una sobreexpressió gènica i proteica de TGF-ß1, CTGF, COL1A i Et-1 en els grups de bleomicina en comparacióa les rates control. Aquesta condició va ser revertida mitjançant el tractament amb CuI que va restablir els valors fins a nivel dels control. A nivell immunohistoquímic els resultats mostren una disminució dels dipòsits de COL1A en el grup tractat comparativament al grup sense tractament. Els anàlisi proteics i inmunohistoquíimics de JAK2, STAT3 i SMAD3 van revelar una sobreexpressió en les rates amb bleomicina mentre que l'expressió proteica va ser inhibida en el grup tractat amb CuI. D'acord amb els resultats obtinguts, l'anàlisi immunohistoquímic del parènquima pulmonar de pacients amb FPI i HP associada mostren sobreeexpresió de les formes fosforilades de JAK2 i STAT3 davant l'absència d'expressió en teixit pulmonar sa. La administració curativa i preventiva d'un inhibidor de la ruta JAK2 / STAT3 pot ser un potencial tractament per la fibrosi pulmonar, ja que millora paràmetres indicatius de la patologia. / Hernández Ribes, G. (2016). ESTUDIO DE LA RUTA CELULAR JAK2/STAT3 COMO POTENCIAL INHIBIDOR EN EL MODELO DE FIBROSIS PULMONAR [Tesis doctoral no publicada]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/64087 / TESIS

In dieser Arbeit werden Untersuchungen an dem transparenten p-Typ-Halbleiter Kupferiodid (CuI) und den ternären Verbindungshalbleitern CuBrxI1-x und AgxCu1-xI vorgestellt. Im ersten Teil der Arbeit liegt der Fokus auf der Untersuchung der dielektrischen Funktion und der optischen Übergänge dieser Materialien. Basierend auf der Kombination von experimentellen Daten und theoretischen Bandstrukturrechnungen werden die beobachteten optischen Übergänge bestimmten elektronischen Übergängen in der Brillouin-Zone zugeordnet. Die optischen Eigenschaften der ternären Legierungen CuBrxI1-x und AgxCu1-xI , insbesondere die exzitonischen Übergangsenergien am Γ-Punkt werden präsentiert. Es wird gezeigt, dass die Bandlückenenergie beider Legierungen ein nichtlineares Verhalten als Funktion der Legierungszusammensetzung aufweist, welches bei tiefen Temperaturen durch einen quadratischen Krümmungsparameter im Bereich von 0.49 eV bis 0.54 eV beschrieben werden kann. Der Ursprung des beobachteten Krümmungsverhaltens wird im Hinblick auf verschiedene Beiträge wie Bindungslängenänderungen und Ladungsumverteilungseffekte diskutiert. Der Einfluss der Legierungszusammensetzung auf die Spin-Bahn-Aufspaltung wird diskutiert, wodurch Rückschlüsse auf die p-d-Hybridisierung der obersten Valenzbänder am Γ-Punkt ermöglicht werden. Es wird gezeigt, dass der Beitrag der metallischen d-Orbitale zum Valenzbandmaximum mit steigendem Br-Gehalt zunimmt, während mit steigendem Ag-Gehalt das Gegenteil der Fall ist. Des Weiteren wird die Temperaturabhängigkeit der Bandlücke für AgxCu1-xI Legierungen in Abhängkeit der Legierungszusammensetzung präsentiert. Es wird gezeigt, dass die Temperaturabhängigkeit der Bandlückenenergie mit steigendem Ag-Gehalt abnimmt, was hauptsächlich auf die Änderung des Beitrags der thermischen Gitterausdehnung zurückzuführen ist. Im zweiten Teil dieser Arbeit werden die bandkantennahen Emissionseigenschaften von CuI Einkristallen vorgestellt. Die Ergebnisse unterstreichen die Notwendigkeit, Exziton-Polariton-Effekte bei der Interpretation der spektralen Linienform der Emissionsspektren und ihrer zeitlichen Entwicklung nach optischer Anregung zu berücksichtigen. Das unterschiedliche transiente Emissionsverhalten der freien und gebundenen Zustände wird durch deren gekoppelte Wechselwirkung erklärt, was eine Abschätzung der Defektdichte im Material ermöglicht. Die Zunahme der Lebensdauer der freien Exziton-Polaritonen mit steigender Temperatur bis etwa 150K deutet auf eine vorwiegend strahlende Rekombination in diesem Temperaturbereich hin, während die Abnahme der Zerfallszeiten bei noch höheren Temperaturen auf eine Zunahme der nicht-strahlenden Rekombinationskanäle hindeutet.:I Introduction 1 II Basics of the Cumulative Part 7 1 Physical properties and concepts . . . . . . . . . . . . . . . . . . . . . . . . . 9 1.1 Copper and silver halides . . . . . . . . . . . . . . . . . . . . . . . . . 9 1.2 Dielectric function . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 1.3 Exciton-polaritons in semiconductors . . . . . . . . . . . . . . . . . . 17 2 Experimental and computational techniques . . . . . . . . . . . . . . . . . . 21 2.1 Sample preparation techniques . . . . . . . . . . . . . . . . . . . . . . 21 2.2 Structural and electrical characterization . . . . . . . . . . . . . . . . 24 2.3 Optical spectroscopy . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 2.4 Density functional theory . . . . . . . . . . . . . . . . . . . . . . . . . 33 III Cumulative Part 35 [C1] Dielectric function of CuBrxI1-x alloy thin films . . . . . . . . . . . . . . . . . 37 [C2] Epitaxial growth of AgxCu1-xI on Al2O3 (0001) . . . . . . . . . . . . . . . . . 56 [C3] Optical properties of AgxCu1-xI alloy thin films . . . . . . . . . . . . . . . . . 64 [C4] Dynamics of exciton-polariton emission in CuI . . . . . . . . . . . . . . . . . 81 IV Summary and Outlook 95 V Publications 101 1 Publications in the basics of the cumulative part . . . . . . . . . . . . . . . . 103 2 Publications forming the cumulative part with contribution by the author . . 119 3 Further publications with contribution by the author . . . . . . . . . . . . . . 120 List of Abbreviations 121 Author Contributions 123 Zusammenfassung nach §11 (4) der Promotionsordnung der Fakultät für Physik und Geowissenschaften der Universität Leipzig 129 / The present work presents investigations on the transparent p-type semiconductor copper iodide (CuI) and the related ternary compound semiconductors CuBrxI1-x and AgxCu1-xI . The first part of the thesis focuses on the study of the dielectric function and related optical transitions of this family of materials. Based on the combination of the experimental data and first principles band structure calculations the observed optical transitions are assigned to specific electronic transitions in the Brillouin zone. The optical properties of ternary CuBrxI1-x and AgxCu1-xI alloys and in particular the excitonic transition energies at the Γ-point as a function of the alloy composition are discussed in detail. It is shown that the bandgap energy of both alloys exhibits non-linear behavior as a function of alloy composition, which can be described by a quadratic bowing parameter in the range of 0.49 eV and 0.54 eV at low temperatures. The origin of the observed bowing behavior is discussed in terms of various physical and chemical contributions, such as changes in bond lengths and charge redistribution effects. The influence of the alloy composition on the spin-orbit splitting energy Δ0 is also discussed in detail, allowing conclusions to be draw down about the p-d hybridization of the top valence bands at the Γ-point. It is shown that the contribution of the metal d orbitals to the valence band maximum increases with increasing Br-content, while the opposite is true for increasing Ag incorporation. In addition to the transition energies at low temperatures, the temperature dependence of the bandgap for AgxCu1-xI alloys as a function of alloy composition is presented. It is shown that the temperature dependent energy shift of the bandgap decreases with increasing Ag content, which is mainly due to the change in the contribution of lattice thermal expansion. In the second part of this work, the properties of the near-band edge emission of CuI single crystals are presented. The obtained results highlight the importance of considering the exciton-polariton effects when interpreting the spectral line shape of the emission peaks as well as their temporal behavior after an optical excitation. The different transient decay characteristics of the free and bound states are explained by their coupled interaction, allowing an approximation of the defect density in the material. With increasing temperature, an increase in the lifetime of the free exciton polaritons was observed up to ca. 150K, indicating mainly radiative recombination in this temperature range. The observed decrease in the decay time at higher temperatures indicates a rapid increase in non-radiative recombination channels.:I Introduction 1 II Basics of the Cumulative Part 7 1 Physical properties and concepts . . . . . . . . . . . . . . . . . . . . . . . . . 9 1.1 Copper and silver halides . . . . . . . . . . . . . . . . . . . . . . . . . 9 1.2 Dielectric function . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 1.3 Exciton-polaritons in semiconductors . . . . . . . . . . . . . . . . . . 17 2 Experimental and computational techniques . . . . . . . . . . . . . . . . . . 21 2.1 Sample preparation techniques . . . . . . . . . . . . . . . . . . . . . . 21 2.2 Structural and electrical characterization . . . . . . . . . . . . . . . . 24 2.3 Optical spectroscopy . . . . . . . . . . . . . . . . . . . . . . . . . . . 27 2.4 Density functional theory . . . . . . . . . . . . . . . . . . . . . . . . . 33 III Cumulative Part 35 [C1] Dielectric function of CuBrxI1-x alloy thin films . . . . . . . . . . . . . . . . . 37 [C2] Epitaxial growth of AgxCu1-xI on Al2O3 (0001) . . . . . . . . . . . . . . . . . 56 [C3] Optical properties of AgxCu1-xI alloy thin films . . . . . . . . . . . . . . . . . 64 [C4] Dynamics of exciton-polariton emission in CuI . . . . . . . . . . . . . . . . . 81 IV Summary and Outlook 95 V Publications 101 1 Publications in the basics of the cumulative part . . . . . . . . . . . . . . . . 103 2 Publications forming the cumulative part with contribution by the author . . 119 3 Further publications with contribution by the author . . . . . . . . . . . . . . 120 List of Abbreviations 121 Author Contributions 123 Zusammenfassung nach §11 (4) der Promotionsordnung der Fakultät für Physik und Geowissenschaften der Universität Leipzig 129

This study evaluates the perceived credibility of a technical chatbot based on its communication style - the way it interacts with its users embodied through text and emojis. A chatbot’s initial communication style was compared to a humble version. The humble communication style was developed from a design workshop held together with six participants and is presented in this paper as a design style guide. The perceived credibility was divided into six dimensions; Competence, Goodwill, Honesty, Predictability, Reputation, and Trustworthiness. The results from the evaluation of the two chatbot versions showed that the credibility was, in general, perceived higher for the chatbot using a humble communication style. Two exceptions were found; (1) the dimension of Trustworthiness stayed at the same level between the versions, and (2) the dimension of Goodwill was perceived higher for the chatbot not using the humble communication style. The satisfaction with the chatbot was measured and resulted in an NPS of 17 for the chatbot using the humble communication style compared to a negative score of -16 for the chatbot not using it. This study found that a more humble communication style would not harm the perceived credibility of a technical professional chatbot. / Den här studien utvärderar den upplevda trovärdigheten hos en teknisk chatbot baserat på dess kommunikationsstil - hur den interagerar med sina användare genom text och emojis. En chatbots initiala kommunikationsstil jämfördes med en ödmjuk version. Den ödmjuka kommunikationsstilen utvecklades från en designworkshop och presenteras i denna studie som en designguide. Den upplevda trovärdigheten delades upp i 6 dimensioner; Kompetens, Välvilja, Ärlighet, Förutsägbarhet, Rykte, och Pålitlighet. Resultatet av utvärderingen av de två chatbot versionerna visade att trovärdigheten upplevdes generellt högre för den ödmjukare chatboten. Två undantag påvisades dock; (1) Pålitlighet blev oförändrad mellan de två kommunikationsstilarna, och (2) Välvilja resulterade i ett högre värde hos den initiala kommunikationsstilen. Användarnas tillfredsställelse med chatboten utvärderades och resulterade i ett NPS värde på 17 för chatboten som använde den ödmjuka kommunikationsstilen igämförelse med ett negativt värde på -16 för chatboten som använde den initiala kommunikationsstilen. Denna studie visade att en mer ödmjuk kommunikationsstil inte skadar den upplevda trovärdigheten hos en teknisk professionell chatbot.