Today, wireless communications is used more then ever before. Wired systems are replaced with wireless versions. New methods and transmission standards are developed and tested. The purpose of this thesis is development of a flexible high-performance System Test Platformfor test of the SoCTRix Wireless LAN Transceiver. The result is a Xilinx Virtex-II FPGA based System Test Platform board with CardBus PC Card interface to a computer. The hardware achieved has the following features: - 8-layer PCB - PCMCIA CardBus PC Card interface, enabling 133 MB/s data throughput - 1M Gate Virtex-II FPGA with reprogrammable configuration memory - Debugging via LEDs and Logic Analyzer connectors - 2x SPI EEPROM - 40 MHz system clock - Easy connection of two daughter-boards Specially designed for wireless transmitter development, can also be used for other computer related highperformance applications.

När den amerikanska investmentbanken Lehman Brothers ansökte om konkurs den 15 september 2008 ökade oron på den globala finansiella marknaden. Detta ledde till svårigheter för finansiella aktörer i Sverige att finansiera sin verksamhet eftersom det blev dyrare att ta upp lån internationellt samtidigt som misstänksamheten gentemot andra aktörer pressade upp riskpremierna. Vid denna tidpunkt var inflationsnivån i Sverige den högsta på 15 år vilket fick Riksbanken att höja styrräntan dagarna innan konkursansökan. När den amerikanska investmentbanken Lehman Brothers ansökte om konkurs den 15 september 2008 ökade oron på den globala finansiella marknaden. Detta ledde till svårigheter för finansiella aktörer i Sverige att finansiera sin verksamhet eftersom det blev dyrare att ta upp lån internationellt samtidigt som misstänksamheten gentemot andra aktörer pressade upp riskpremierna. Vid denna tidpunkt var inflationsnivån i Sverige den högsta på 15 år vilket fick Riksbanken att höja styrräntan dagarna innan konkursansökan. Uppsatsens undersökning har till stor del bestått av en litteraturstudie. Utöver detta har även en intervju genomförts med riksbankschefen Stefan Ingves. Materialet som har använts har främst tagits från Riksbanken. Riksbanken vidtog ett flertal åtgärder för att stärka den svenska finansmarknadens motståndskraft. Åtgärderna var under krisens gång en kombination av penningpolitik och finansiella stabiliseringsåtgärder. Utöver räntejusteringar erbjöds bland annat obegränsade lånemöjligheter till Riksbankens motparter, vilket enligt Stefan Ingves även var den viktigaste åtgärden. Detta syftade främst till att sänka den allmänna räntenivån och återskapa förtroendet på den svenska finansiella marknaden. Till följd av Riksbankens åtgärder föll den allmänna räntenivån. Vilka effekter Riksbankens åtgärder hade på inflations och BNP utvecklingen är dock svårt att fastställa då utvecklingen av dessa berodde på flera olika faktorer. Riksbankens agerande under finanskrisen stämmer väl överens med vad teorierna förespråkar. Problemet med de penningpolitiska teorierna är att handlingsutrymmet begränsas när styrräntan närmar sig nollgränsen samtidigt som konjunkturnedgången är ihållande. Trots att Riksbanken agerade i enlighet med de penningpolitiska teorierna kan händelseförloppet inte enbart förklaras av dessa. Riksbanken agerande som en Lender of Last Resort är teorienlig förutom att en alldeles för låg straffränta togs ut.

The vitamin D metabolite 1,25(OH)2D3 has long been known to inhibit growth of prostate cancer cells and this mainly through a VDR-mediated pathway controlling target gene expression, resulting in cell cycle arrest, apoptosis and differentiation. Another major way in which 1,25(OH)2D3 inhibits cell growth in prostate cancer is via membrane-initiated steroid signalling, which triggers activation of signal cascades upon steroid binding to a receptor complex, leading to induction of genes regulating cell growth, proliferation and apoptosis. The main prostate cancer inhibiting membrane-initiated route is the TGFβ signalling pathway, elicited by the protein TGFβ. Two other important proteins downstream in this cascade are Smad2 and Smad3. In this study the early effects of 1,25(OH)2D3 on activated Smad2/3 levelsin PC-3 prostate cancer cells were examined. PC-3 cells were incubated for 3, 5, 10, 30 and 60 minutes as well as 38 hours both together with 1,25(OH)2D3 of the concentrations 10-10 and 10-7 M and without. Western Blots were then performed on supernatants from the cells treated followed by treatment of the membranes with primary antibodies against phosphorylated Smad2/3 C-terminal linker regions, alkaline phosphatase conjugated secondary antibodies and finally visualization with BCIP/ NBT tablets. As the downstream cascade protein JNK is a proposed activator of Smad2/3, this procedure was also repeated with a JNK inhibitor. This is a follow-up to an earlier study which examined the influence of 1,25(OH)2D3 on TGFβ levels using the same doses and time points and which found that 1,25(OH)2D3 initially lowered the level of active TGFβ, then increased it. The results of this study indicated a 1,25(OH)2D3 mediated induction of the same pattern in the levels of active Smad2 and 3, both with and without JNK inhibitor. The results did not indicate that 1,25(OH)2D3 activates the Smad2/3 C-terminal linker region via the JNK pathway.

The vitamin D metabolite 1,25(OH)2D3 has long been known to inhibit growth of prostate cancer cells and this mainly through a VDR-mediated pathway controlling target gene expression, resulting in cell cycle arrest, apoptosis and differentiation. Another major way inwhich 1,25(OH)2D3 inhibits cell growth in prostate cancer is via membrane-initiated steroid signalling, which triggers activation of signal cascades upon steroid binding to a receptor complex, leading to induction of genes regulating cell growth, proliferation and apoptosis. The main prostate cancer inhibiting membrane-initiated route is the TGFβ signalling pathway, elicited by the protein TGFβ. Another important protein downstream in this cascade is Smad2. In this study the early effects of 1,25(OH)2D3 on activated Smad2 levels in PC-3 prostate cancer cells were examined. PC-3 cells were incubated for 5, 10, 30 and 60 minutes as well as 24 and 40 hours both together with 1,25(OH)2D3 of the concentrations 10-10 and 107 M and without. An ELISA assay scanning for activated Smad2 was then performed on supernatants from both treated and untreated cells. This is a follow-up to an earlier study which examined the influence of 1,25(OH)2D3 on TGFβ levels using the same doses and similar time points and which found that 1,25(OH)2D3 initially lowered the level of active TGFβ, then increased it. The results of this study showed a statistically insignificant, time delayed 1,25(OH)2D3 mediated induction of the same pattern in the levels of active Smad2. / Project Work in Biomedicine, Advanced Level, 7.5 ECTS

Tablet PC is not a brand-new idea. But it did not draw much attention of consumers in the past. However tablet PC became the hottest product since Apple released the iPad in April 2010 which hit 15 million sales record in less than nine months. And this fever drives all of the IT, PC, mobile companies to start their production line. A war of tablet PC is about to begin in 2011. But from consumers¡¦ perspective, is tablet PC so different from its counterpart being utilized currently that attracts consumer to use it? What are the factors influencing the intention to use tablet PC? To answer the question, this study presents an extended technology acceptance model (TAM) integrating innovation diffusion theory and perceived price to examine the factors that influence the adoption of tablet PC. And the proposed model was empirically tested through data collected from an online questionnaire with 536 samples. And principal analysis, ANOVA, multiple regression as well as descriptive statistics were conducted to analyze the data. The findings indicate that all of the factors proposed in the model anticipate potential users¡¦ intention to use tablet PC. Among the factors, perceived enjoyment, perceived ease of use, relative advantage have the most significant influence and image is the least one. This study may extend use of TAM and provide further insights into tablet PC marketing strategies.

An approach to parallelize the simulation of AC-Radial Shipboard Power Systems (SPSs) using multicore computers is presented. Time domain simulations of SPSs are notoriously slow, due principally to the number of components, and the time-variance of the component models. A common approach to reduce the simulation run-time of power systems is to formulate the electrical network equations using modified nodal analysis, use Bergeron's travelling-wave transmission line model to create subsystems, and to parallelize the simulation using a distributed computer. In this work, an SPS was formulated using loop analysis, defining the subsystems using a diakoptics-based approach, and the simulation parallelized using a multicore computer. A program was developed in C# to conduct multithreaded parallel-sequential simulations of an SPS. The program first represents an SPS as a graph, and then partitions the graph. Each graph partition represents a SPS subsystem and is computationally balanced using iterative refinement heuristics. Once balanced subsystems are obtained, each SPS subsystem's electrical network equations are formulated using loop analysis. Each SPS subsystem is solved using a unique thread, and each thread is manually assigned to a core of a multicore computer. To validate the partitioning approach, performance metrics were created to assess the speed gain and accuracy of the partitioned SPS simulations. The simulation parameters swept for the performance metrics were the number of partitions, the number of cores used, and the time step increment. The results of the performance metrics showed adequate speed gains with negligible error. An increasing simulation speed gain was observed when the number of partitions and cores were augmented, obtaining maximum speed gains of <30x when using a quadcore computer. Results show that the speed gain is more sensitive to the number partitions than is to the number of cores. While multicore computers are suitable for parallel-sequential SPS simulations, increasing the number of cores does not contribute to the gain in speed as much as does partitioning. The simulation error increased with the simulation time step but did not influence the partitioned simulation results. The number of operations caused by protective devices was used to determine whether the simulation error introduced by partitioning SPS simulations produced a inconsistent system behavior. It is shown, for the time step sizes uses, that protective devices did not operate inadvertently, which indicates that the errors did not alter RMS measurement and, hence, were non-influential.

From the perspective of contingency theory, this study investigates the governance change of the organization value chain between upstream and downstream firms in three most important high-tech industries in Taiwan: PC, semiconductor, and TFT-LCD. Many scholars and experts have thoroughly studied governances of value chains. Their findings are valuable to the competitiveness of organizations and industries. However, most of them are focused on the Western industries. Very few studies are based on Taiwanese industries. Besides, most of these researches on the characteristics of Taiwanese organizations and industries emphasize the flexible production collaborative networks and the quick responses of small and medium-sized enterprises (SMEs). Even fewer studies have recognized that Taiwanese high-tech industries have evolved into large integrated business groups. This study complements previous literature from a different perspective. Employing case research method, this research has interviewed 20 experts that are familiar with the operation of these three high-tech electronic industries. It is found that all PC, IC and TFT-LCD industries adopted network models at the emerging stage. When these industries getting matured, however, the IC industry adopted the market model, while the PC and TFT-LCD industries moved to hierarchy models. Using Boolean method, this study has reached four major findings for Taiwan¡¦s high-tech industries: 1. The industries¡¦ governance of organization value chain moved toward the personal network model at the emerging stage due to technology uncertainties, relatively high profitability and not enough capital munificence. 2. The industries¡¦ governance of organization value chain moved toward the impersonal network model at the emerging stage due to technology uncertainties, low complexity of technology, relatively high profitability, and enough capital munificence. 3. The industries¡¦ governance of organization value chain moved toward the market model at the mature stage due to technology certainties, enough capital munificence, high complexity of technology and relatively high profitability. 4. The industries¡¦ governance of organization value chain moved toward the hierarchy model at the mature stage due to technology certainties, enough capital munificence, low complexity of technology and relatively low profitability. In the concluding chapter, this thesis presents management implications and future researches based on this study.

<p>The vitamin D metabolite 1,25(OH)2D3 has long been known to inhibit growth of prostate cancer cells and this mainly through a VDR-mediated pathway controlling target gene expression, resulting in cell cycle arrest, apoptosis and differentiation. Another major way in which 1,25(OH)2D3 inhibits cell growth in prostate cancer is via membrane-initiated steroid signalling, which triggers activation of signal cascades upon steroid binding to a receptor complex, leading to induction of genes regulating cell growth, proliferation and apoptosis. The main prostate cancer inhibiting membrane-initiated route is the TGFβ signalling pathway, elicited by the protein TGFβ. Two other important proteins downstream in this cascade are Smad2 and Smad3. In this study the early effects of 1,25(OH)2D3 on activated Smad2/3 levelsin PC-3 prostate cancer cells were examined. PC-3 cells were incubated for 3, 5, 10, 30 and 60 minutes as well as 38 hours both together with 1,25(OH)2D3 of the concentrations 10-10 and 10-7 M and without. Western Blots were then performed on supernatants from the cells treated followed by treatment of the membranes with primary antibodies against phosphorylated Smad2/3 C-terminal linker regions, alkaline phosphatase conjugated secondary antibodies and finally visualization with BCIP/ NBT tablets. As the downstream cascade protein JNK is a proposed activator of Smad2/3, this procedure was also repeated with a JNK inhibitor. This is a follow-up to an earlier study which examined the influence of 1,25(OH)2D3 on TGFβ levels using the same doses and time points and which found that 1,25(OH)2D3 initially lowered the level of active TGFβ, then increased it. The results of this study indicated a 1,25(OH)2D3 mediated induction of the same pattern in the levels of active Smad2 and 3, both with and without JNK inhibitor. The results did not indicate that 1,25(OH)2D3 activates the Smad2/3 C-terminal linker region via the JNK pathway.</p>

<p>The vitamin D metabolite 1,25(OH)2D3 has long been known to inhibit growth of prostate cancer cells and this mainly through a VDR-mediated pathway controlling target gene expression, resulting in cell cycle arrest, apoptosis and differentiation. Another major way inwhich 1,25(OH)2D3 inhibits cell growth in prostate cancer is via membrane-initiated steroid signalling, which triggers activation of signal cascades upon steroid binding to a receptor complex, leading to induction of genes regulating cell growth, proliferation and apoptosis. The main prostate cancer inhibiting membrane-initiated route is the TGFβ signalling pathway, elicited by the protein TGFβ. Another important protein downstream in this cascade is Smad2. In this study the early effects of 1,25(OH)2D3 on activated Smad2 levels in PC-3 prostate cancer cells were examined. PC-3 cells were incubated for 5, 10, 30 and 60 minutes as well as 24 and 40 hours both together with 1,25(OH)2D3 of the concentrations 10-10 and 107 M and without. An ELISA assay scanning for activated Smad2 was then performed on supernatants from both treated and untreated cells. This is a follow-up to an earlier study which examined the influence of 1,25(OH)2D3 on TGFβ levels using the same doses and similar time points and which found that 1,25(OH)2D3 initially lowered the level of active TGFβ, then increased it. The results of this study showed a statistically insignificant, time delayed 1,25(OH)2D3 mediated induction of the same pattern in the levels of active Smad2.</p> / Project Work in Biomedicine, Advanced Level, 7.5 ECTS

<p>USB has become a popular interface for exchanging data between PC’s and peripherals. An increasing number of portable peripherals are using the USB interface to communicate with the PC.The design and implementation of a synthesizable model of the USB 1.1 protocol engine is presented in this report The PHY is compatible with the USB 1.1 transceiver macrocell interface (UTMI) specification and the simulation test confirmed the successful operation of circuits for both full speed (12 Mbps) and low speed (1.5 Mbps) data transmission. the model is written completely in behavioral verilog with a top down approach and the model was verified and validated.</p>