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The Global ETD Search service is a free service for researchers
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Showing 11 to 20 of 20 (0.022 seconds)Spelling suggestions: "subject:"equol"" "subject:"dquol""
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Oestrogenic compounds and oxidative stress (in human sperm and lymphocytes in the Comet assay)Anderson, Diana, Baumgartner, Adolf, Brinkworth, Martin H., Schmid, Thomas E., Cemeli, Eduardo, Wood, John M. January 2003 (has links)
No / Reactive oxygen species (ROS) are produced by a wide variety of chemicals and physiological processes in which enzymes catalyse the transfer of electrons from a substrate to molecular oxygen. The immediate products of such reactions, superoxide anion radicals and hydrogen peroxide can be metabolised by enzymes such as superoxide dismutase (SOD) and catalase (CAT), respectively, and depending on its concentration by Vitamin C (Vit C). Under certain circumstances the ROS form highly reactive hydroxyl radicals. We examined human sperm and lymphocytes after treatment with six oestrogenic compounds in the Comet assay, which measures DNA damage, and observed that all caused damage in both cell types. The damage was diminished in nearly all cases by catalase, and in some instances by SOD and Vit C. This response pattern was also seen with hydrogen peroxide. This similarity suggests that the oestrogen-mediated effects could be acting via the production of hydrogen peroxide since catalase always markedly reduced the response. The variable responses with SOD indicate a lesser involvement of superoxide anion radicals due to SOD-mediated conversion of superoxide to hydrogen peroxide generally causing a lower level of DNA damage than other ROS. The variable Vit C responses are explained by a reduction of hydrogen peroxide at low Vit C concentrations and a pro-oxidant activity at higher concentrations. Together these data provide evidence that inappropriate exposure to oestrogenic compounds could lead to free-radical mediated damage. It is believed that the observed activities were not generated by cell free cell culture conditions because increased responses were observed over and above control values when the compounds were added, and also increasing dose¿response relationships have been found after treatment with such oestrogenic compounds in previously reported studies.
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Die Wirkung von Genistein und Equol in Kombination mit Vibrationstraining auf Knochenparameter der orchidektomierten Ratte während einer Knochendefektheilung / The effect of Genistein and Equol combined with vibration therapy on bone parameters during the bone healing of an orchiectomized ratHenze, Sara 16 March 2016 (has links)
No description available.
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Die therapeutischen Effekte von Estradiol, Dihydrotestosteron, Genistein und Equol auf den osteoporotischen Knochen der orchidektomierten männlichen Sprague-Dawley-Ratte / Therapeutic effects of estradiol, dihydrotestosterone, genistein and equol on osteoporotic bone of orchidectomized male Sprague Dawley ratVorwerk, Elena 08 December 2010 (has links)
No description available.
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Einfluss von Estradiol, Genistein, Equol und Resveratrol auf verschiedene östrogensensitive Organe und Parameter der ovariektomierten Maus / Influence of Estradiol, Genistein, Equol and Resveratrol on different estrogen-sensitive organs and parameters in the ovarectomized mouseMählmeyer, Sandra 02 February 2011 (has links)
No description available.
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Einfluss eines 30-Hz-Vibrationstrainings in Kombination mit verschiedenen Isoflavonen auf die proximale Tibiametaphyse der ovarektomierten Ratte / Effects of a 30 Hz whole-body vibration training in combination with various isoflavones on the proximal metaphysis of the ovariectomized rat tibiaSandmann, Fabian 08 November 2011 (has links)
No description available.
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| 16 |
Neuroendocrine effects of the endocrine disruptors Vinclozolin and Equol in the adult male rat / Neuroendokrine Effekte der endokrinen Disruptoren Vinclozolin und Equol in der erwachsenen männlichen RatteLoutchanwoot, Panida 19 November 2007 (has links)
No description available.
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| 17 |
Die Wirkung von Sexual- und Phytohormonen auf das Remodelling des osteoporotischen Knochens der orchiektomierten Ratte nach Trepanation und Vibration / The influence of sexual and phytohormones on remodelling of the osteoporotic bone of male rat after trepanation and whole-body-vibration.Thole, Sonja Wilma 26 March 2014 (has links)
No description available.
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Impact of Short-Term Isoflavone Intervention in Polycystic Ovary Syndrome (PCOS) Patients on Microbiota Composition and MetagenomicsHaudum, Christoph, Lindheim, Lisa, Ascani, Angelo, Trummer, Christian, Horvath, Angela, Münzker, Julia, Obermayer-Pietsch, Barbara 20 April 2023 (has links)
Background: Polycystic ovary syndrome (PCOS) affects 5–20% of women of reproductive age worldwide and is associated with disorders of glucose metabolism. Hormone and metabolic signaling may be influenced by phytoestrogens, such as isoflavones. Their endocrine effects may modify symptom penetrance in PCOS. Equol is one of the most active isoflavone metabolites, produced by intestinal bacteria, and acts as a selective estrogen receptor modulator. Method: In this interventional study of clinical and biochemical characterization, urine isoflavone levels were measured in PCOS and control women before and three days after a defined isoflavone intervention via soy milk. In this interventional study, bacterial equol production was evaluated using the log(equol: daidzein ratio) and microbiome, metabolic, and predicted metagenome analyses were performed. Results: After isoflavone intervention, predicted stool metagenomic pathways, microbial alpha diversity, and glucose homeostasis in PCOS improved resembling the profile of the control group at baseline. In the whole cohort, larger equol production was associated with lower androgen as well as fertility markers. Conclusion: The dynamics in our metabolic, microbiome, and predicted metagenomic profiles underline the importance of external phytohormones on PCOS characteristics and a potential therapeutic approach or prebiotic in the future.
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Der Einfluss von Sexual- und Phytohormonen sowie Ganz-Körper-Vibration auf die Wundheilung des osteoporotischen Knochens der männlichen Ratte / The influence of sexual and phytohormones as well as whole-body vibration on wound healing of osteoporotic bone of the male ratSzentmiklossy von Primocz, Johannes Pal 26 March 2014 (has links)
No description available.
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Kurzzeiteffekte von Estradiol, Raloxifen, Phytohormonen und Parathormon auf die metaphysäre Frakturheilung des manifest osteoporotischen Knochens der Ratte / Effects of estradiol, raloxifene, cimicifuga racemosa, equol, genistein and parathyroid hormone on early metaphyseal fracture healing in osteoporotic ratsDaub, Florian 16 June 2010 (has links)
No description available.
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