On estime que plus de la moitié de population mondiale sait parler au moins deux langues et que 40% de cette population bilingue utilise les deux langues au quotidien. Les psycholinguistes et les neuropsycholinguistes se sont rapidement intéressés au fonctionnement du cerveau bilingue et à la façon dont deux langues pouvaient partager un seul cerveau. Ainsi, de nombreuses recherches ont porté sur la représentation de plusieurs langues dans le cerveau ainsi que sur les mécanismes permettant de passer d’une langue à l’autre, mais aussi sur la période développementale sensible à l’apprentissage des langues.Dans ce travail, nous nous sommes intéressés au rôle de l’âge d’acquisition et du niveau de compétence des deux langues sur a) la représentation des substrats cérébraux, b) la plasticité cérébrale et c) la capacité d’alterner entre les deux langues. Pour cela nous comparons des locuteurs bilingues précoces -qui ont appris les deux langues avant 3 ans- et des locuteurs bilingues tardifs -qui ont appris la deuxième langue après 10 ans- tous ayant atteint un très bon niveau de compétence dans les deux langues. Le niveau langagier et le fonctionnement exécutif des participants ont été mesurés à l’aide de plusieurs tâches linguistiques et non linguistiques. Grâce à la technique d’imagerie par résonances magnétiques fonctionnelles (IRMf), nous avons pu identifier les substrats neuronaux des deux langues pour chacun des groupes, les aires impliquées dans le contrôle des langues ainsi que les changements cérébraux dus à l’apprentissage précoce de deux langues. De manière générale, les résultats montrent que la compétence langagière, plutôt que l’âge d’acquisition, aurait un rôle essentiel sur la représentation des langues. En revanche, l’âge d’acquisition serait déterminant en ce qui concerne la structure cérébrale des certaines aires impliquées dans les processus langagiers. / It is estimated that more than half of the world's population speaks two languages and that 40% of the population uses both languages on a daily basis. Psycholinguists and neuropsycholinguists became interested early in the way in which two languages could share a single brain. They have therefore been interested in the representation of several languages in the bilingual brain, in the sensitive period during which languages are learned and also in the mechanisms that allow bilinguals to switch from one language to another without apparent effort. In this work, we investigated the role of the age of acquisition and proficiency of languages and the influence of two languages a) on the representation of cerebral substrates of two languages, b) on the cerebral plasticity, c) and on the mechanisms of language control. For this purpose, we compare early bilingual speakers, who learned both languages before the age of 3 years, and late bilingual speakers who learned the second language after 10 years, both of whom had a very good level of proficiency in both languages. Participants were assessed in a wide range of linguistic and non-linguistic tasks to measure language level and executive functioning. Using the functional magnetic resonance imaging technique, we were able to identify the neuronal substrates of the two languages for each group and the areas involved in language control, as well as cerebral changes due to the early learning of two languages. In general, the results show that language proficiency, rather than the age of acquisition, has an essential role on the representation of languages, but that the age of acquisition is decisive in regards of cerebral structure of certain areas related to language.

Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder characterized by difficulty paying attention, impulsivity, and hyperactivity. Diagnosis of ADHD rose 42% from 2003–2004 to 2011–2012. In 2011, 3.5 million children were treated with drugs. Optimizing therapy can take a year, and may not be completely effective. A clinical trial is currently being conducted of a device/drug combination using the computer game Minecraft, to determine how certain activities affect executive function, working memory, and restraint in patients diagnosed with ADHD. The human subjects’ responses are being modeled using artificial neural networks (ANNs), an artificial intelligence method that can be utilized to interpret highly complex data. We propose using ANNs to optimize drug and Minecraft therapy for individual patients based on the initial NICHQ Vanderbilt assessment scores. We are applying ANNs in the development of computational models for executive function deficiencies in ADHD. These models will then be used to develop a therapeutic video game as a drug/device combination with stimulants for the treatment of ADHD symptoms in Fragile X Syndrome. As a first step towards the design of virtual subjects with executive function deficits, computational models of the core executive functions working memory and fluid intelligence were constructed. These models were combined to create healthy control and executive function-deficient virtual subjects, who performed a Time Management task simulation that required the use of their executive functions to complete. The preliminary working memory model utilized a convolutional neural network to identify handwritten digits from the MNIST dataset, and the fluid intelligence model utilized a basic recurrent neural network to produce sequences of integers in the range 1-9 that can be multiplied together to produce the number 12. A simplified Impulsivity function was also included in the virtual subject as a first step towards the future inclusion of the core executive function inhibition.

La plupart des travaux empiriques ont montré que les jeunes et les âgés utilisent de nombreuses stratégies pour accomplir des tâches cognitives. Ils mettent aussi en évidence que les âgés (a) utilisent moins de stratégies, (b) utilisent les stratégies disponibles dans des proportions différentes, (c) exécutent moins efficacement les stratégies utilisées, et (d) choisissent, sur chaque problème, moins fréquemment la meilleure stratégie que les jeunes. L’objectif général de cette thèse était de déterminer quels sont les mécanismes sous-tendant la différence de performances jeunes/âgés dans ces différentes dimensions stratégiques. Nous testons l’hypothèse que le déclin des fonctions exécutives médiatise les différences liées à l’âge dans le répertoire, la distribution, l’exécution et la sélection stratégiques. Pour atteindre cet objectif, nous avons adopté une approche corrélationnelle et une approche expérimentale. Les résultats répliquent les principales données concernant les différences jeunes/âgés dans les différentes dimensions stratégiques. De plus, ils mettent en évidence le rôle essentiel des fonctions exécutives, et, en particulier, de la flexibilité cognitive et de l’inhibition, dans la diminution avec l’âge du répertoire, de la sélection et de l’exécution stratégiques. Nous discutons les implications de ces résultats sur le vieillissement et les variations stratégiques, d’une part, et sur les modèles de la sélection stratégique, d’autre part. / Empirical studies on strategic variations during aging have shown that young andolder adults use multiple strategies to accomplish cognitive tasks. They also showed that older adults (a) use fewer strategies, (b) do not use available strategies with the same frequency as young adults (c) execute strategies less efficiently, and (d) select less frequently the best strategy than young adults. The aim of this study was to investigate which mechanisms underly the strategic differences in young and older adults. We tested the hypothesis that age related decline of executive functions mediate age-related differences in strategy repertoire, distribution, execution, and selection. To achieve these ends, we adopted correlational and experimental approaches. Results replicated previous data relative to differences between young and older adults in different strategy dimensions. Results also highlight crucial role ofexecutive functions, especially cognitive flexibility and inhibition, in strategy repertoire, selection, and execution. Implications for further our understanding of aging and strategic variations, as well as current theoretical models of strategy selection are discussed.

No description available.

No description available.

Previous research indicates that many important changes in executive functions, or higher cognitive capacities, occur between the ages of three and five years. Additionally, a distinction can be made between the cognitive functions associated with two different cortical regions. The functions of the dorsolateral prefrontal cortex (DL-PFC) are assessed using 'cool' tasks that are abstract and decontextualised. In contrast, the functions of the orbitofrontal cortex (OFC) are assessed using 'hot' tasks that require flexible appraisal of the affective significance of stimuli (Zelazo & Müller, 2002). Different clinical populations have been hypothesized to differ in terms of their impairment on tasks associated with each area of functioning. Current research conclusions regarding the primacy of hot versus cool executive function impairments are limited, however, as they have not taken complexity into account. That is, tasks currently used in investigations of hot and cool executive functions might differ in terms of the complexity of the cognitive processes that the tasks require. Therefore, comparisons across tasks may be misleading because these tasks vary in terms of the demands they place on participants as well as their hot versus cool status. While complexity theories have been applied to a number of cool tasks, only one hot task, those measuring theory-of-mind abilities, have been analysed in terms of complexity. One aim of the current research was to modify several tasks presumed to measure OFC performance to include a complexity manipulation. Tasks from three hot domains (conditional discrimination, the Children's Gambling Task, and future-oriented decision-making) were analysed in terms of their relational complexity, that is, the number of related entities or arguments inherent in a task or concept (Halford, 1993). Based on these complexity analyses, binary-relational and ternary-relational items of each of these tasks were developed or existing tasks were selected and/or modified. The binary-relational items were closely matched to the ternary-relational items in terms of stimuli and procedure, however, they were lower in complexity. After pilot testing, the three new measures of hot executive functioning were included in a larger test battery that was administered to a sample of 120 normally developing 3-, 4-, 5- and 6-year-old children. Existing binary- and ternary-relational items assessing theory-of-mind (a hot task) and three cool measures (transitivity, class inclusion and the Dimensional Change Card Sort test) were also included. The inclusion of measures of both hot and cool executive functions, each with complexity manipulated, allowed for the examination of a possible differential age of emergence of executive abilities associated with the DL-PFC versus the OFC. In support of the relational complexity approach, significant complexity effects were found across all seven tasks. Items at a higher level of complexity were experienced as relatively more difficult by children of all ages. Significant effects of age were also observed, with performance across all tasks increasing with age. The age effects were strongest on the ternary-relational items. The pass-fail data indicated that the majority of children in all age groups succeeded on the binary-relational items. However, it was not until a median of five years of age that children were able to process ternary relations. Consequently, the ternary-relational items produce the greatest differences in performance between the four age groups. The overall pattern of the results also suggested that a distinction can be made between the ages of emergence of abilities associated with the OFC versus the DL-PFC. The results of the pass-fail percentages, patterns of age-related change and age effects on domain factor scores all suggested that while hot executive functions may begin to develop around four years of age, similar levels of improvement are not seen in cool executive functions until five years of age. Thus, the ability to succeed on ternary-relational items of hot executive function tasks appeared to emerge slightly earlier than the cool executive function tasks. Complexity appears to be a critical factor underlying children's performance on executive function tasks, and future assessment regarding the development of executive abilities will benefit from keeping this in mind. While some refinement of new task items may be beneficial, the current test battery may have utility in further examinations of the executive profiles underlying clinical groups, such as children with autism and ADHD.

<p>Studiens syfte var att med neuropsykologiska utredningsverktyg undersöka exekutiva funktioner hos allsvenska fotbollsspelare samt division 1 spelare. Även sambandet mellan spelarnas exekutiva funktioner, gjorda mål och assist undersöktes. 57 herr- och damspelare testades. Elva kliniska utredningstest användes. Resultaten visade att de allsvenska spelarna hade signifikant bättre kapacitet på vissa exekutiva funktioner än spelarna från division 1. Även de spelare som gjort flest mål och assist hade i förhållande till de som gjort minst, bättre kapacitet på flertalet exekutiva funktioner. Den förklarade variansen visade att de exekutiva funktionerna, i vissa fall, utgjorde mellan 30 % och 40 % av samtliga egenskaper som påverkar spelarnas prestationsförmåga mätt i mål och assist. Resultaten indikerar att kapaciteten av de exekutiva funktionera kan ha betydelse för fotbollspelares sportsliga framgång.</p> / <p>The purpose of this study was to, with neuropsychological test tools, examine the executive functions among soccer players from premier league and first division. The relations between the players’ executive functions and their goals and assists were also examined. 57 male and female soccer players were tested. Eleven different clinical test tools were used. The result shows that the players from premier league had significant better capacity of their executive functions than the players from the first division. Also the players who scored most goals and did most assist had better capacity in several of their executive functions than the players that scored and assisted least. R Square showed in some cases that 30 to 40 % of the total capacity of the players’ performance in assists and goal scoring were provided by the executive functions. The result indicates that the capacity of the executive functions among soccer players could have importance for their success.</p>

The general aim of this thesis was to extend knowledge of the interplay between self-regulation (SR) skills during childhood in relation to academic achievement and later adult educational and occupational attainment. Previous research has shown that cool SR (i.e., cognitive) is more closely linked to academic achievement than hot SR (i.e., motivational/emotional). However, studies investigating both cool and hot SR in relation to academic achievement have been restricted to young children. Therefore, Study I assessed cool and hot SR in relation to academic achievement over a longer time period. The results showed that cool SR at age 3 was related to achievement already at age 6. Hot SR at age 3 did not predict achievement until later on in elementary school. Study II investigated the contribution of interference control and attention skills at age 6 to concurrent and later academic achievement at age 10. As the learning material becomes increasingly more complex throughout elementary school and teachers may give less support, interference control was expected to have a delayed effect on academic achievement relative to attention skills. Results showed that attention skills were related to academic achievement at age 6, whereas interference control only predicted academic achievement at age 10. Study III investigated task persistence in young adolescence in relation to academic achievement later in school and educational and occupational attainment in midlife. Results showed that task persistence contributed to change in grades between ages 13 and 16. Further, task persistence predicted later educational and occupational attainment (men only). Importantly, individual differences in intelligence, motivation, social background, and later educational attainment did not account for these effects. The findings point to a fundamental role of self-regulation in childhood for successful academic achievement and later attainment in adulthood. / At the time of doctoral defense, the following papers were unpublished and had a status as follows: Paper 1: Manuscript. Paper 2: Manuscript.

Studiens syfte var att med neuropsykologiska utredningsverktyg undersöka exekutiva funktioner hos allsvenska fotbollsspelare samt division 1 spelare. Även sambandet mellan spelarnas exekutiva funktioner, gjorda mål och assist undersöktes. 57 herr- och damspelare testades. Elva kliniska utredningstest användes. Resultaten visade att de allsvenska spelarna hade signifikant bättre kapacitet på vissa exekutiva funktioner än spelarna från division 1. Även de spelare som gjort flest mål och assist hade i förhållande till de som gjort minst, bättre kapacitet på flertalet exekutiva funktioner. Den förklarade variansen visade att de exekutiva funktionerna, i vissa fall, utgjorde mellan 30 % och 40 % av samtliga egenskaper som påverkar spelarnas prestationsförmåga mätt i mål och assist. Resultaten indikerar att kapaciteten av de exekutiva funktionera kan ha betydelse för fotbollspelares sportsliga framgång. / The purpose of this study was to, with neuropsychological test tools, examine the executive functions among soccer players from premier league and first division. The relations between the players’ executive functions and their goals and assists were also examined. 57 male and female soccer players were tested. Eleven different clinical test tools were used. The result shows that the players from premier league had significant better capacity of their executive functions than the players from the first division. Also the players who scored most goals and did most assist had better capacity in several of their executive functions than the players that scored and assisted least. R Square showed in some cases that 30 to 40 % of the total capacity of the players’ performance in assists and goal scoring were provided by the executive functions. The result indicates that the capacity of the executive functions among soccer players could have importance for their success.

Working memory is a mental system that is related to cognitive control and higher cognition. Although the topic of working memory is well researched, there is a great deal of debate about the mechanisms that drive individual differences in working memory capacity. Moreover, little is known about the direct relationships between different types of working memory tasks. The present study uses structural equation modeling to examine three varieties of working memory task: The complex span, running memory span, and visual arrays. It is found that, while complex and running span performance is directly predicted by immediate memory and retrieval from long-term memory, visual arrays is directly predicted by attention control. Despite these differences, all tasks are found to be united by executive attention, which is conceptualized as an executive process that is apparent across several types of attention and memory task. A second analysis examines the relationship between working memory and general fluid intelligence. It is concluded that, while executive attention accounts for the largest portion of the correlation between working memory and fluid intelligence, immediate memory and retrieval from long term memory are also critical to explaining this relationship.