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  • About
  • The Global ETD Search service is a free service for researchers to find electronic theses and dissertations. This service is provided by the Networked Digital Library of Theses and Dissertations.
    Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
11

Combinaison de l'inhibition du protéasome et d'un nouveau composé dans le traitement du myélome multiple / Association of proteasome inhibition and a new compound in the treatment of multiple myeloma

Ourabah, Sarah 23 March 2018 (has links)
Résumé confidentiel / Confidential abstract
12

RUGGED AND RELIABLE COTS STORAGE SOLUTIONS FOR DATA ACQUISITION SYSTEMS

Tsur, Ofer 10 1900 (has links)
International Telemetering Conference Proceedings / October 20-23, 2003 / Riviera Hotel and Convention Center, Las Vegas, Nevada / Due to the rotating mechanism in mechanical disks, they cannot provide the top-level reliability required for operation in harsh military environments. This paper describes three COTS alternatives to mechanical disks: ruggedized mechanical disks, solid-state flash disks and stacked PC Cards. It discusses their cost-effectiveness and aspects such as environmental specifications, endurance and data reliability. It highlights several methods used by flash disks to enhance endurance and reliability, as well as flash pricing and density trends. It presents data security requirements in actual emergency situations, and how flash disks can meet these requirements. It concludes with a feature-by-feature comparison of ruggedized disks, flash disks and stacked PC Cards.
13

TRENDS IN COTS STORAGE SOLUTIONS FOR DATA ACQUISITION SYSTEMS

Tsur, Ofer 10 1900 (has links)
ITC/USA 2005 Conference Proceedings / The Forty-First Annual International Telemetering Conference and Technical Exhibition / October 24-27, 2005 / Riviera Hotel & Convention Center, Las Vegas, Nevada / This paper discusses data storage requirements for data acquisition systems, and evaluates the ability of three of the most popular COTS data storage solutions - mechanical disk, ruggedized mechanical disk and solid-state flash disk - to meet these requirements today and in the future. It addresses issues of capacity, data reliability, endurance, form factor, cost and security. It concludes with a discussion of trends to implement high-speed serial interfaces in data acquisition systems, and the challenges that these trends pose for COTS storage solutions.
14

Open source vývojová prostředí pro Javu a kontrola kvality kódu

Roh, Jiří January 2006 (has links)
Pro potřebu kontroly kvality kódu v Javě lze jednak využít funkce vývojového prostředí, ale také i samostatné programy, které kvalitu kódu hlídají - analyzéry kódu. Ty lze použít v podobě pluginů pro vývojová prostředí. V této práci jsem se primárně zaměřoval na vývojová prostředí NetBeans a Eclipse a jejich podporu pro různé analyzéry kódu (FindBugs, PMD, atd.) z oblasti open source. Práce se zabývá analýzou kontroly kvality ve vývojových prostředích a analyzérech kódu.
15

A Behavior-Driven Recommendation System for Stack Overflow Posts

Greco, Chase D 01 January 2018 (has links)
Developers are often tasked with maintaining complex systems. Regardless of prior experience, there will inevitably be times in which they must interact with parts of the system with which they are unfamiliar. In such cases, recommendation systems may serve as a valuable tool to assist the developer in implementing a solution. Many recommendation systems in software engineering utilize the Stack Overflow knowledge-base as the basis of forming their recommendations. Traditionally, these systems have relied on the developer to explicitly invoke them, typically in the form of specifying a query. However, there may be cases in which the developer is in need of a recommendation but unaware that their need exists. A new class of recommendation systems deemed Behavior-Driven Recommendation Systems for Software Engineering seeks to address this issue by relying on developer behavior to determine when a recommendation is needed, and once such a determination is made, formulate a search query based on the software engineering task context. This thesis presents one such system, StackInTheFlow, a plug-in integrating into the IntelliJ family of Java IDEs. StackInTheFlow allows the user to intervi act with it as a traditional recommendation system, manually specifying queries and browsing returned Stack Overflow posts. However, it also provides facilities for detecting when the developer is in need of a recommendation, defined when the developer has encountered an error messages or a difficulty detection model based on indicators of developer progress is fired. Once such a determination has been made, a query formulation model constructed based on a periodic data dump of Stack Overflow posts will automatically form a query from the software engineering task context extracted from source code currently open within the IDE. StackInTheFlow also provides mechanisms to personalize, over time, the results displayed to a specific set of Stack Overflow tags based on the results previously selected by the user. The effectiveness of these mechanisms are examined and results based the collection of anonymous user logs and a small scale study are presented. Based on the results of these evaluations, it was found that some of the queries issued by the tool are effective, however there are limitations regarding the extraction of the appropriate context of the software engineering task yet to overcome.
16

Interfacing a processor core in FPGA to an audio system

Mateos, José Ignacio January 2006 (has links)
<p>The thesis project consists on developing an interface for a Nios II processor integrated in a board of Altera (UP3- 2C35F672C6 Cyclone II).</p><p>The main goal is show how the Nios II processor can interact with the other components of the board.The Quartus II software has been used to create to vhdl code of the interfaces, compile it and download it into the board. The Nios II IDE tool is used to build the C/C++ files and download them into the processor.</p><p>It has been prepared an application for the audio codec integrated in the board (Wolfson WM8731 24-bit sigma-delta audio CODEC). The line input of the audio codec receives an analog signal from a laptop, this signal is managed by the control interface of the audio codec. The converters ADCs and DACs are stereo 24-bit sigma delta and they are used with oversampling digital interpolation and decimation filters.</p><p>The digital interface of the audio codec sends the digital signal to the Nios II processor and receives the data from the processor. After building the interfaces for the audio codec and the processor, it has been prepared an application in C++ language for the processor that modifies the volume of the signal.</p><p>The signal come back to the audio codec and it is possible to check the results with headphones or speakers at the line output of the audio codec.</p>
17

Improving resource availability for geospatial information infrastructures

Dí­az Sánchez, Laura 07 May 2010 (has links)
Los sistemas de información construidos mediante servicios distribuidos basados en estándares se han convertido en el paradigma de computación adoptado por defecto por la comunidad geoespacial para la construcción de infraestructuras de información. Diferentes disposiciones gubernamentales, como la Directiva Europea INSPIRE, recomiendan normas para compartir recursos (por ejemplo, datos y procesos) con el objetivo de mejorar el estudio del medio ambiente (y otros campos similares) y la toma de decisiones.La mayoría de las infraestructuras de información geoespacial (IIG) atienden necesidades básicas tales como acceso a datos, visualización y descarga, sin embargo, tienen escasos enlaces a servicios de geoprocesamiento. Además, la mayorí¬a de infraestructuras geoespaciales se han construido siguiendo un enfoque del tipo top-down, donde sólo a los proveedores oficiales (por lo general los organismos públicos) se les permite desplegar y mantener recursos. Debido a que los mecanismos para desplegar e integrar recursos en estas infraestructuras son tecnológicamente complejos, existe una muy limitada participación por parte de los usuarios, provocando a la larga la escasez de recursos actualizados.Para hacer frente a estas limitaciones, se presenta en este trabajo, una arquitectura distribuida basada en los principios de INSPIRE y ampliada con un componente llamado ServiceFramework. Este componente proporciona capacidad de procesamiento, ofreciendo una funcionalidad existente en forma de servicio estándar de procesamiento. También mejora la integración ad hoc y el despliegue de recursos de información geoespacial dentro de la infraestructura. El ServiceFramework trata la necesidad de mejorar la disponibilidad de recursos de datos geoespaciales, proporcionando mecanismos para generar de forma automática servicios compatible con INSPIRE.Estas contribuciones son evaluadas en dos escenarios diferentes dentro de dos proyectos europeos. En el proyecto AWARE, se demuestra cómo un grupo de hidrólogos puede beneficiarse del acceso a las infraestructuras geoespaciales donde pueden compartir capacidades de procesamiento. En el proyecto EuroGEOSS, demostramos cómo mejorar la disponibilidad de los recursos geoespaciales para analizar un escenario forestal. Se prevé que estas nuevas metodologí¬as, pueden aumentar la participación de usuarios más expertos en la creación de infraestructuras de información geoespacial, lo que aumenta la utilidad y el valor de estas infraestructuras.
18

Interfacing a processor core in FPGA to an audio system

Mateos, José Ignacio January 2006 (has links)
The thesis project consists on developing an interface for a Nios II processor integrated in a board of Altera (UP3- 2C35F672C6 Cyclone II). The main goal is show how the Nios II processor can interact with the other components of the board.The Quartus II software has been used to create to vhdl code of the interfaces, compile it and download it into the board. The Nios II IDE tool is used to build the C/C++ files and download them into the processor. It has been prepared an application for the audio codec integrated in the board (Wolfson WM8731 24-bit sigma-delta audio CODEC). The line input of the audio codec receives an analog signal from a laptop, this signal is managed by the control interface of the audio codec. The converters ADCs and DACs are stereo 24-bit sigma delta and they are used with oversampling digital interpolation and decimation filters. The digital interface of the audio codec sends the digital signal to the Nios II processor and receives the data from the processor. After building the interfaces for the audio codec and the processor, it has been prepared an application in C++ language for the processor that modifies the volume of the signal. The signal come back to the audio codec and it is possible to check the results with headphones or speakers at the line output of the audio codec.
19

Frege IDE nad JetBrains MPS / Frege IDE with JetBrains MPS

Satmári, István January 2018 (has links)
Frege is an open-source project which brings the popular functional programming language Haskell to the Java ecosystem. JetBrains MPS is an open-source language workbench which allows users to design a new language and build an integrated development environment with a projectional (structured) editor for the created language. In this work we analyzed Frege grammar and created an IDE based on MPS that assists developers with writing code in the Frege language. Our environment includes a set of intuitive editors for editing Frege syntax, provides a simple type checking and implements code generators for the Frege language. Aim of the Frege IDE is its usability. Additionally, the thesis compares projectional editors with the more common plain-text IDEs, such as Eclipse, and evaluates whether they offer any advantage for editing purely functional programming languages.
20

Alterações tomográficas pulmonares na artrite reumatoide

Koch, Milene Caroline January 2015 (has links)
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em Ciências Médicas, Florianópolis, 2015 / Made available in DSpace on 2016-05-24T17:24:27Z (GMT). No. of bitstreams: 1 338989.pdf: 509773 bytes, checksum: af680f166f1ab4e4301255bed239699f (MD5) Previous issue date: 2015 / Objetivos: a Artrite Reumatoide (AR) classicamente afeta as articulações, porém pode apresentar manifestações extra-articulares, incluindo pulmonares. Neste estudo, busca-se identificar possíveis fatores de risco ou marcadores laboratoriais para o comprometimento pulmonar na AR, especialmente a presença de Fator Reumatoide (FR), anticorpos contra proteínas citrulinadas (ACPA) e marcadores tumorais, relacionando-os às alterações observadas em tomografias computadorizadas de alta resolução (TCAR) do tórax. Método: estudo transversal com portadores de AR entrevistados e examinados por médico especialista e depois submetidos à TCAR do tórax e a coletas sanguíneas para medidas de proteína C reativa (PCR), velocidade de hemossedimentação (VHS), fator reumatoide (FR), ACPA (anti-vimentina e/ou anti-CCP3) e dos marcadores tumorais antígeno carcinoembrionário (CEA), CA 125, CA 15-3 e CA 19-9. Resultados: 96 pacientes realizaram a TCAR do tórax sendo os achados mais frequentes o espessamento brônquico (27/28,1%) e as bronquiectasias (25/26,0%). O FR esteve presente em 63,2% (55/87) e os ACPA (anti-vimentina ou anti-CCP3) em 72,7% (64/88) dos indivíduos. O CEA apresentou-se elevado em 27,5% dos indivíduos não tabagistas e em 67,6% de tabagistas. O CA 19-9 apresentou-se elevado em 6 (7,0%) de 86 pacientes, o CA 15-3 em 3 (3,5%) de 85 pacientes e o CA 125 em 4 (5,3%) de 75 pacientes. Na análise multivariada, foi identificada uma associação estatisticamente significativa entre a elevação do CEA e a presença de alteração em vias aéreas nos pacientes com AR (p=0,014). Conclusões: A elevação do CEA está associada à presença de alteração em vias aéreas em AR. O CEA pode servir como um preditor de doença pulmonar na AR, selecionando os indivíduos que merecem uma maior investigação do aparelho respiratório.<br> / Abstract : Introduction: Rheumatoid arthritis (RA) classically affects the joints but can present extra-articular manifestations, including pulmonary manifestations. The present study aimed to identify possible risk factors or laboratory markers for lung involvement in RA, particularly the presence of rheumatoid factor (RF), anti-citrullinated peptide antibodies (ACPA), and tumor markers, and to correlate them with changes observed on chest high-resolution computerized tomography (HRCT). Method: This cross-sectional study involved RA patients who were examined and questioned by a specialist physician and later subjected to chest HRCT and blood collection for measurement of C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), rheumatoid factor (RF), ACPA (anti-vimentin and/or anti-CCP3), and the tumor markers carcinoembryonic antigen (CEA), CA 125, CA 15-3, and CA 19-9. Results: A total of 96 patients underwent chest HRCT. The most frequent findings were bronchial thickening (27/28.1%) and bronchiectasis (25/26.0%). RF was present in 63.2% (55/87) of patients, and ACPA (anti-vimentin or anti-CCP3) were present in 72.7% (64/88) of patients. CEA levels were high in 27.5% of non smokers and 67.6% of smokers. CA-19-9 levels were high in 6 of 86 patients (7.0%), CA 15-3 levels were high in 3 of 85 patients (3.5%), and CA 125 levels were high in 4 of 75 patients (5.3%). Multivariate analysis indicated a statistically significant association between high CEA levels and the presence of airway changes in patients with RA (p=0.014). Conclusions: The elevation of CEA is associated with the presence of airway disease in AR .CEA can serve as a predictor of lung disease in RA and can help identify individuals who require more detailed examination for the presence of respiratory disorders.

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