abstract: Despite the extensive research on the consequences of migration, little is known about the effects of seasonal migration on fertility, contraception and sexually transmitted diseases in the countries of former Soviet Union, that have undergone vast demographic changes in the last two decades. Using cross-sectional data from two surveys conducted in Armenia in 2005 and 2007, this dissertation is exploring the effects of seasonal migration on reproductive behavior and outcomes, as well as sexual health among women left-behind. The dissertation is constructed of three independent studies that combined draw the broad picture of the consequences of seasonal migration in this part of the world. The first study, "Seasonal migration and fertility in low-fertility areas of origin" looks at the effect of seasonal migration on yearly pregnancy rates, lifetime fertility, and fertility preferences among women and their husbands. The models are fitted using discrete-time logistic regression, and random-intercept logistic regression for negative binomial and binary outcomes, correspondingly. The findings show that seasonal migration in low-fertility settings does not further disrupt fertility levels in a short-, or long-run, contradicting to the findings from high-fertility settings. However, the study provides some evidence that seasonal migration is associated with increased fertility preferences among migrant men. The second study, "Seasonal migration and contraception among women left-behind", examines the associations between migration and modern contraceptive use, by looking at current contraceptive use and the history of abortions. A series of random-intercept logistic regression models reveal that women with migrant partners are significantly less likely to use modern contraceptives, than women married to non-migrants. They also have higher rates of abortions; however this effect is moderated by the socioeconomic status of the household. The third study, "Seasonal migration and risks of sexually transmitted diseases (STDs) among women left-behind", looks at the effects of seasonal migration on the diagnosed STDs in the last three years, and self reported STD-like symptoms in the last twelve months. The results of random-intercept logistic regression for negative binomial and binary outcomes provide strong evidence of increased STD risks among migrants' wives; however, this effect is also moderated by the household income. / Dissertation/Thesis / Ph.D. Sociology 2011

A proposta desta dissertação é analisar como os governos de esquerda da América Latina contribuem ou não para a construção, desenvolvimento e consolidação de uma cultura democrática na região. A partir da experiência recente de Brasil e de Venezuela, que representam hoje os dois modelos dominantes da esquerda latino-americana, investiga-se se os resultados sociais obtidos estimulam ou não a confiança dos cidadãos no regime democrático. Para alcançar esse objetivo, verifica-se se houve ou não avanço em educação e saúde nos dois países entre 1990 e 2008. Tal diagnóstico é confrontado com a opinião de brasileiros e venezuelanos sobre a satisfação com a vida cotidiana e com o grau de apoio à democracia no mesmo período. A partir dos dados analisados, pode-se concluir que há avanços, no entanto, as medidas implementadas na área social são insuficientes para se consolidar a dimensão social da democracia e fortalecer substancialmente a cultura democrática. / The proposal of this dissertation is to examine how the governments on the left in Latin America contribute or not contribute to the construction, development and consolidation of a democratic culture in the region. Since the recent experience in Brazil and Venezuela, which now represent the two dominant models of the Latin American left, investigates whether the results obtained social stimulate or no public confidence in the democratic system. To achieve this goal, it is whether there is progress in education and health in both countries between 1990 and 2008. This diagnosis is confronted with the view of Brazilians and Venezuelans on satisfaction with life and the degree of support for democracy in the same period. From the data, it can be concluded that there is progress, however, the measures implemented in the social area are insufficient to strengthen the social dimension of democracy and substantially strengthen the democratic culture.

Doctor of Philosophy / Department of Statistics / Christopher Vahl / Veterinary drugs are used extensively for disease prevention and treatment in food producing animals. The residues of these drugs and their metabolites can pose risks for human health. Therefore, a withdrawal time is established to ensure consumer safety so that tissue, milk or eggs from treated animals cannot be harvested for human consumption until enough time has elapsed for the residue levels to decrease to safe concentrations. Part of the process to establish a withdrawal time involves a linear regression to model drug residue depletion over time. This regression model is used to calculate a one-sided, upper tolerance limit for the amount of drug residue remaining in target tissue as a function of time. The withdrawal period is then determined by finding the smallest time so that the upper tolerance limit falls below the maximum residue limit. Observations with measured residue levels at or below the limit of quantitation (LOQ) of the analytical method present a special challenge in the estimation of the tolerance limit. Because values observed below the LOQ are thought to be unreliable, they add in an additional source of uncertainty and, if dealt with improperly or ignored, can introduce bias in the estimation of the withdrawal time. The U.S. Food and Drug Administration (FDA) suggests excluding such data while the European Medicine Agency (EMA) recommends replacing observations below the LOQ with a fixed number, specifically half the value of the LOQ. However, observations below LOQ are technically left censored and these methods are do not effectively address this fact. As an alternative, a regression method accounting for left-censoring is proposed and implemented in order to adequately model residue depletion over time. Furthermore, a method based on generalized (or fiducial) inference is developed to compute a tolerance limit with results from the proposed regression method. A simulation study is then conducted to compare the proposed withdrawal time calculation procedure to the current FDA and EMA approaches. Finally, the proposed procedures are applied to real experimental data.

The 1960s have a special place in the cultural memory of the West Coast of Canada. They have informed its regional identity, the cityscape of Vancouver, and the social infrastructure of the modern state. But lost in the mythos that has surrounded Vancouver’s long sixties is the story of the Georgia Straight. Founded by a group of poets in 1967 to combat a campaign launched by the municipal government to discriminate against the counterculture, it is today, in 2018, the most prosecuted newspaper in Canadian history. Between 1967 and 1972, the municipal and provincial government deliberately took advantage of the legal justice system to censor an outlet for dissent, with the end goal of inhibiting it from publishing. This thesis challenges popular conceptions of the 1960s in British Columbia’s popular memory by demonstrating the extent to which the state deliberately censored freedom of expression by attempting to silence an outlet for dissent, and highlights how the municipal and provincial government infringed on the civil liberties of Vancouver’s counterculture community, in one instance in August 1971, threatening it with outright violence. / Graduate

Speckle tracking echocardiography (STE) is a relatively new imaging modality that enables the direct measurement of active contractile myocardial tissue in an offline analysis. This is accomplished through a software algorithm that tracks collections of acoustic markers, known as 'speckles', that are unique to a given section of myocardium. By measuring the displacement of these 'speckles' as the heart contracts and relaxes, STE produces parameters of the strain, or percent change in length, exhibited by the myocardium. As multiple studies have shown, this strain data produced by tracking of the global left atrium has the ability to accurately assess the physiologic functions of the atrium as a reservoir, conduit and booster pump in the cardiac cycle. Despite these valuable correlations, there are noted problems with STE regarding acoustic cluttering and disappearance of 'speckles' that can occur as the selected region of interest moves out of the field of view or becomes obscured. These problems may be increased when tracking an extended region of myocardium. Therefore, this present study sought to test a new method of assessing left atrial function with STE strain analysis by focusing on a concise region of the atrium, specifically the interatrial septum. To test this, the echocardiograms of 37 patients were obtained and grouped according to the designation of their cardiac function as normal (n=11), abnormal (n=12), or exhibiting signs of cardiac amyloidosis (n=14). In all patients, STE strain analysis was performed on the both the global left atrium and the interatrial septum. Measurements of the mean peak strain observed in the resultant strain curves were recorded for both STE scans of each patient. The curves produced by the tracking the segments of the entire atrium (6 segments) and interatrial septum (3 segments) were compared based on the exhibited changes in strain seen in the relative shapes of the curves, as well as the spread of the segmental strain curves about the calculated mean strain curve. Additionally, the number of segments that were either unsuccessfully or incorrectly tracked was recorded as a measure of the accuracy of STE. As a final step, the interatrial strain curves of four selected patients in the various states of ventricular diastolic dysfunction were chosen and compared with data obtained from scans of mitral flow echocardiography and tissue Doppler imaging (TDI) in an attempt to correlate the exhibited changes in strain shown in the interatrial septum with the physiologic functions of the atrium during ventricular diastole. The results showed that the mean peak strain of the global atrial strain trace decreased from normal (41.32%±10.8) to abnormal (21.69%±13.8) to the amyloid group (10.41%±6.9). This trend was echoed in the mean peak strain measured in the interatrial septum, as measured in normal (64.2%±15.6), abnormal (28.37%±13.4) and amyloid groups (12.21%±12.1). When the strain curves of the entire atrium and interatrial septum were compared, they demonstrated similar patterns in the timing of changes in strain, however the strain curves of the individual interatrial septum segments showed a much more concise grouping about the mean strain curve and were less likely to exhibit discordant segmental strain curves that deviated from the pattern established by all other segments in the trace. Additionally, within the STE scans of the global atrium, the interatrial septum exhibited a higher percentage of successfully tracked segments than did the lateral atrial wall; this trend was universally exhibited in all three groups. Finally, the interatrial septum strain curves, mitral flow echocardiography and TDI scans all demonstrated similar indications of left atrial function in the four selected patients. Ultimately, STE strain analysis of the interatrial septum appears to be a more accurate method of tracking the atrial myocardium than STE tracing of the global left atrium. Furthermore, it shows viable potential as a method for assessing the global physiologic function of the left atrium, as indicated by the similarities between the trends exhibited by these STE scans and the data gathered from scans produced by mitral flow echocardiography and TDI.

Sub-endocardial fibres line the inner surface of both ventricles and are responsible for longitudinal oscillations of the mitral annulus, such oscillations may be measured using tissue Doppler echocardiography (IDE). During systole the annulus descends and during early diastole (ETDE) and atrial systole (ATDE) itascends. This thesis examined whether changes in the velocity of the annulus ineach of these phases of oscillation, measured using tissue Dopplerechocardiography (TDE), could determine the nature of increases in left ventricular size (pathological or physiological). Study one examined differences at rest in longitudinal velocities between individuals with hypertrophic cardiomyopathy (HCM), hypertension (HT), weightlifters, runners and controls, (n = 15 all groups) and all groups were aged between 20 - 36 years. The results demonstrated that both pathological groups had systolic and ETDE velocities significantly lower than groups with physiological hypertrophy (weightlifters or runners) or controls p < 0.05. AIDE however was not significantly different between groups. Additionally runners also demonstrated a significantly higher ETDE than either weightlifters or controls (p < 0.05). Binomial logistic regression identified longitudinal systolic velocity < 9 cm s" 1 and ETDE velocity < 11 cm s" 1 as the best combination of variables to predict pathological increases in heart size. Study two examined older subjects in order to determine whether the criteria set out in study one were applicable to senior athletes. The subject groups were the same as in study one however all subjects were aged between 36-55. In this case systolic annular velocity was significantly lower in groups with pathological LVH but ETDE < 9 cm s" 1 was a better differentiator. Binomial logistic regression identified ETDE < 9 cm s" 1 and a mitral E / A ratio < 1 as the best combination of variables to predict pathological LVH. Study three examined the age related changes in long axis function using the pooled data from studies one and two. This demonstrated that in the pathological LVH groups only ETDE / ATDE ratio was significantly correlated with age (r = - 0.5 p < 0.05) suggesting that there appears to be no summation of the effects of pathology and age on mitral annular velocities. The control groups demonstrated a significant age related reduction in all long axis variables (systolic velocity r = - 0.7 p < 0.05; ETDE r = - 0.6 p < 0.01; ATDE r = 0.5 p < 0.05; ETD E / ATDE r = - 0.5 p< 0.01). Weightlifters however did not demonstrate an age related decline in either systolic or diastolic annular velocities. Runners had no age related decline in systolic annular velocities, and whilst they had an age dependent fall in ETDE ( r = - 0.62 p < 0.05) the older runners ETDE were still significantly faster (p < 0.05) than that seen in control subjects. Study four investigated relationship between mitral annular velocity and VOiruK in runners, weightlifters and controls. These results demonstrated peak exercise E TDE strongly correlated to VO^PEAK (r = 0.8 p < 0.01). ConclusionsTaken together these data suggest that longitudinal velocities of the mitral annulus may be useful in determining the nature of increases in heart size, in addition the increased performance of endurance - trained athletes is due in part to functional changes of the long axis.

The thesis "The Problems in Writing of Left-handed Pupils" is focused on the dificulties in the first steps of writing of left-handed children in primary schools. The thesis is divided into two parts. In the theoretic part we deal with the laterality and the left-handness in general. Further we deal with the development of left-handness in the history and nowadays and first of all with the development of motor skills of the left-handed children in the preschool age. The next aim is to chart the difficulties in the preschool period and the potencional problems in writing. The main part of our thesis is focused on the correct methodological help with writing in the first class in primary schools. The other part of our thesis is practical part. In this part we focus on the analysis of the writing edacation for the left-handed pupils in the first classes in the schools in Central Bohemian Region. We studied the quantity of the left-handed boys and the left-handed girls, the correct holding of writing tools, the slope of paper, the slope of letters, the correct sitting, the using of ergonomic tools and the using of pens or pencils.

135f. / Submitted by Oliveira Santos Dilzaná (dilznana@yahoo.com.br) on 2013-08-26T15:18:09Z No. of bitstreams: 1 DISSERT_VERSAO_FINAL Thais Brito da Silva.pdf: 617058 bytes, checksum: 966d0431991e10dbe6ab5f440cfa44da (MD5) / Approved for entry into archive by Ana Portela(anapoli@ufba.br) on 2013-08-26T15:44:04Z (GMT) No. of bitstreams: 1 DISSERT_VERSAO_FINAL Thais Brito da Silva.pdf: 617058 bytes, checksum: 966d0431991e10dbe6ab5f440cfa44da (MD5) / Made available in DSpace on 2013-08-26T15:44:04Z (GMT). No. of bitstreams: 1 DISSERT_VERSAO_FINAL Thais Brito da Silva.pdf: 617058 bytes, checksum: 966d0431991e10dbe6ab5f440cfa44da (MD5) Previous issue date: 2010 / CAPES / Esta pesquisa apresenta uma análise das posições políticas dos movimentos sociais articulados em torno do jornal Brasil de Fato sobre o governo Lula. Por um lado, a respeito de como este governo se relaciona com o bloco de poder e a hegemonia política no Brasil; por outro lado, como se relaciona com estes movimentos e em que medida contribui ou não com processos contra hegemônicos. As questões suscitadas na pesquisa foram desenvolvidas a partir da análise de conteúdo das edições do jornal Brasil de Fato no período de 2003 a 2007, nos meses de janeiro, março, junho, setembro e dezembro de cada ano. Ao todo, foram estudadas 25 edições das primeiras semanas dos meses indicados. O pensamento de Antonio Gramsci (1891-1937) e o legado teórico da sua produção intelectual é o referencial teórico principal da análise. Considerando a perspectiva gramsciana que identifica a vida estatal como uma contínua formação e superação de equilíbrios instáveis entre os interesses dos grupos fundamentais e os interesses dos grupos subordinados, o estudo apresenta as posições políticas dos movimentos sociais articulados no jornal Brasil de Fato sobre o governo Lula e coloca problemas e questões relacionados a um cenário de convivência entre alianças de classes, concessões programáticas e tentativas de conciliação de interesses conflitantes empreendidas pelo governo Lula. Ao mesmo tempo, tem-se uma conjuntura identificada, inicialmente, como favorável aos movimentos sociais, que demonstram esperar que o governo realize as mudanças ansiadas pelas classes populares, que faça reformas estruturais, mas é um cenário que vai se mostrando, nas avaliações dos intelectuais que se posicionaram no Brasil de Fato, desestruturador das forças de esquerdas no país. This research presents an analysis over the political facts and acts of social movements during Luis Inácio Lula da Silva's government as presented in Brasil de Fato newspaper. In one hand, is presented how government related with the political hegemony in Brazil. In the other, how does it related with the social movements and in what degree the government contributed or not with counterhegemony processes. That questions developed in this research rose during the analysis of 25 editions of Brasil de Fato newspapers from the first weeks of January, March, June, September and December, from 2003 to 2007. Antonio Gramsci's (1891-1937) theories is the intellectual basis of the analysis. We consider Gramsci perspective that identifies the state life as a continuous training and upgrading of unstable balance between the interests of key groups and interests of subordinate groups, the study presents the political views of social movements in Brazil de Fato newspaper about the Lula government and poses problems and issues related to a scenario of coexistence of class alliances, awards program and attempts to reconcile conflicting interests taken by this government. At the same time, the situation initially identified as favorable to the social movements - that expected the government to make changes yearn for the working classes - to make structural reforms, became – as showed on the evaluations of intellectuals who were stationed in Brasil de Fato - a scenario of destructuring the left a scenario that in the country. / Salvador

This work aims to analyze the discourses of the press intentona Communist Pernambuco in 1935. Because these speeches helped and contributed to a negative image of the left in Brazil. Thus, several issues were relevant to an analysis of this intense study, as ideology, left and right and also as the press was used to build these issues in a distorted analysis of those who participated in the communist movement. We see listed in the official newspaper of Pernambuco left pejorative terms such as extremists, anarchy, disorder and other leading newspapers of the party (player) to see the movement as something detrimental to society. These terms have influenced the popular imagination a malicious look on the left. / Este trabalho tem como objetivo analisar os discursos da imprensa escrita Pernambucana a intentona comunista de 1935. Como esses discursos ajudaram e contribuíram para uma imagem negativa da esquerda no Brasil. Desta forma, vários temas foram relevantes para uma análise intensa deste estudo, como ideologia, esquerda e direita e também como a imprensa se utilizou desses assuntos para construção de uma análise deturpada daqueles que participaram do movimento comunista. Observamos nos enunciados dos jornais oficiais de Pernambuco termos pejorativos à esquerda, como extremistas, anarquista, desordem entre outros, induzindo o interlocutor dos jornais (leitor) a ver o movimento como algo prejudicial à sociedade. Esses termos influenciaram no imaginário popular um olhar nocivo à esquerda.

Made available in DSpace on 2015-07-22T20:50:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-03-25. Added 1 bitstream(s) on 2015-08-11T03:25:40Z : No. of bitstreams: 1 Publico-057a.pdf: 1544247 bytes, checksum: d76c2d7c07bfd1b50436489da9d22288 (MD5). Added 1 bitstream(s) on 2015-08-11T03:25:40Z : No. of bitstreams: 2 Publico-057a.pdf: 1544247 bytes, checksum: d76c2d7c07bfd1b50436489da9d22288 (MD5) Publico-057b.pdf: 1030631 bytes, checksum: 9562ff77059213eafe1900cb95553c45 (MD5) / Objetivo:Estabelecer o diagnóstico da hipertrofia ventricular esquerda(HVE)em pacientes com doença renal crônica(DRC)em programa de hemodiálise(HD)por sete diferentes critérios eletrocardiográficos, assim como pela radiografia de tórax,correlacionando estes dois métodos propedêuticos com o índice de massa do ventrículo esquerdo (IMVE)obtido pelo ecocardiograma.Métodos:Estudo transversal que incluiu 100 pacientes(58 homens e 42 mulheres,idade média de 46,2 ± 14,0 anos)com DRC de todas as etiologias,há pelo menos seis meses em HD.Foram obtidos ecocardiograma,eletrocardiograma e radiografia de tórax dos pacientes,sempre até uma hora após o término das sessões de HD.Resultados:A HVE foi detectada em 83pacientes(83 por cento),dos quais 56 (67,4 por cento)apresentavam o padrão concêntrico e 27(32,6 por cento)o padrão excêntrico de HVE.O tempo médio dos pacientes em HD foi de 50,7 ± 46,5 meses, mediana de 33,5 meses.A média do IMVE foi de 154,9± 57,3 g/m2.Todos os métodos eletrocardiográficos estudados e o índice cardiotorácico(ICT)apresentaram sensibilidade,especificidade e acurácia diagnósticas acima de 50 por cento.Pela correlação linear de Pearson com o IMVE apenas o critério de Sokolow-Lyon voltagem não apresentou coeficiente ≥ 0,50.Já o cálculo da razão de verossimilhança mostrou que o tanto o ECG como a radiografia de tórax possuem poder discriminatório para diagnóstico de HVE na população estudada,com ênfase para os critérios de Cornell produto e Romhilt-Estes.Não houve correlação entre o IMVE com o intervalo QTc e sua dispersão.Conclusões:O eletrocardiograma e a radiografia de tórax são métodos seguros,úteis,eficazes e de alta reprodutibilidade no diagnósticode HVE dos pacientes em HD.A utilidade do ECG é realçada pela capacidade de detectar alterações eletrofisiológicas,como o intervalo QTc e sua dispersão. / Objective: To establish the diagnosis of left ventricular hypertrophy (LVH) in haemodialysis (HD) patients with chronic kidney disease (CKD) using seven different electrocardiographic criteria and chest radiography, and to correlate these two diagnostic methods with left ventricular mass index (LVMI) as obtained by echocardiogram. Methods: Cross-sectional study including 100 patients (58 men and 42 women, mean age of 46.2 ± 14.0 years) with CKD of all causes, undergoing HD for at least six months. Echocardiogram, electrocardiogram and chest radiography were obtained from all patients, always up to one hour after the end of the HD sessions. Results: LVH was detected in 83 patients (83%), of which 56 (67.4%) presented a concentric pattern and 27 (32.6%) an eccentric pattern of LVH. The patients had been undergoing HD for a mean time of 50.7 ± 46.5 months, median of 33,5 months. The mean LVMI was 154.9 ± 57.3 g/m2. All electrocardiographic methods studied and the cardiothoracic ratio (CTR) had diagnostic sensitivity, specificity and accuracy higher than 50%. Using Pearson’s linear correlation with LVMI, only the Sokolow-Lyon voltage criterion did not present a 0.50 coefficient. The calculation of the likelihood ratio, in turn, showed that both ECG and chest radiography have a discriminatory power for the diagnosis of LVH in the population studied, with emphasis on for the Cornell product and Romhilt-Estes criteria. No correlation was found between LVMI and QTc and QTc dispersion. Conclusions: Electrocardiogram and chest radiography are safe, useful, efficient and highly reproducible methods for the diagnosis of LVH in HD patients. The usefulness of ECG is stressed by its ability to detect electrophysiological changes such as QTc and QTc dispersion. / TEDE / BV UNIFESP: Teses e dissertações