Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2015-10-23T14:10:54Z No. of bitstreams: 1 NecienneDePaulaCarneiroPorto_DISSERT.pdf: 1841553 bytes, checksum: 3545fb3d3d9bc281739a4a80d031bab2 (MD5) / Approved for entry into archive by clediane guedes (clediane@bczm.ufrn.br) on 2015-10-23T20:22:43Z (GMT) No. of bitstreams: 1 NecienneDePaulaCarneiroPorto_DISSERT.pdf: 1841553 bytes, checksum: 3545fb3d3d9bc281739a4a80d031bab2 (MD5) / Made available in DSpace on 2015-10-23T20:22:43Z (GMT). No. of bitstreams: 1 NecienneDePaulaCarneiroPorto_DISSERT.pdf: 1841553 bytes, checksum: 3545fb3d3d9bc281739a4a80d031bab2 (MD5) Previous issue date: 2013-06-27 / Introdu??o: a avalia??o da press?o inspirat?ria nasal (SNIP) ? considerada uma manobra complementar da Press?o Inspirat?ria M?xima est?tica (PImax) em v?rias condi??es cl?nicas, por?m n?o h? relatos na obesidade. Por outro lado, a obesidade tem um importante impacto nos m?sculos respirat?rios especialmente com maiores gordura abdominal o que provavelmente pode ser detectado na avalia??o da SNIP que mensura mais precisamente a press?o diafragm?tica. Objetivo: analisar em obesos a rela??o entre SNIP e vari?veis respirat?rias e marcadores de adiposidade. Material e M?todo: num estudo transversal um total de 92 obesos (38.3?10.2 anos) sem hist?ria de doen?a respirat?ria ou card?aca diagnosticada. Foram avaliados na espirometria (capacidade vital for?ada-CVF; volume expirat?rio for?ado no primeiro segundo-VEF1; volume de reserva expirat?rio-VRE) e press?es respirat?rias est?tica (PImax, PEmax e SNIP) e din?mica (ventila??o volunt?ria m?xima-VVM). Sendo considerados os marcadores de adiposidade: ?ndice de adiposidade corporal-IAC; ?ndice de massa corporal-IMC e circunfer?ncias do quadril (CQ), cintura (CC) e pesco?o (CP). Resultados: 65 obesos m?rbidos (IMC=50.8?8.1Kg/m2) e 27 obesos n?o m?rbidos (IMC=35.6?2.7Kg/m2) foram homog?neos (p>0.05) na SNIP (99.1?24.5cmH2O, 87% do predito) e PImax (107.3?26.4cmH2O, 109% do predito). Existe correla??o (r=0.5) entre SNIP e PImax somente no grupo de obesos m?rbidos. De acordo com as correla??es houve associa??o entre vari?veis respirat?rias (CVF r=0.48; VEF1 r=0.54; e VVM r=0.54), valores antropom?tricos (idade r=-0.44) e SNIP somente para os obesos m?rbidos. Esses achados foram certificados quando tamb?m comparados a quantidade de gordura ao redor do pesco?o (CP?43cm). O modelo de regress?o linear stepwise mostrou que a VVM parece ser o melhor preditor para explicar a SNIP nos obesos m?rbidos. Nestes obesos a SNIP foi levemente mais baixa (87%predito) que os valores esperados para indiv?duos brasileiros saud?veis. Conclus?o: em obesos m?rbidos a SNIP ? moderadamente relacionada a PImax. A SNIP parece ser mais relacionada a VVM que ? marcadores de adiposidade.

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2017-07-03T12:17:44Z No. of bitstreams: 1 MariaHelenaVieiraDeMelo_DISSERT.pdf: 1200116 bytes, checksum: 18ff16af8c77b5da46b3a799b3da7fdd (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2017-07-05T15:40:57Z (GMT) No. of bitstreams: 1 MariaHelenaVieiraDeMelo_DISSERT.pdf: 1200116 bytes, checksum: 18ff16af8c77b5da46b3a799b3da7fdd (MD5) / Made available in DSpace on 2017-07-05T15:40:57Z (GMT). No. of bitstreams: 1 MariaHelenaVieiraDeMelo_DISSERT.pdf: 1200116 bytes, checksum: 18ff16af8c77b5da46b3a799b3da7fdd (MD5) Previous issue date: 2017-05-05 / O objetivo do presente estudo foi avaliar e comparar a espessura dos m?sculos levantadores do ?nus em mulheres com s?ndrome dos ov?rios polic?sticos e com ciclo menstrual normal. Atrav?s de um estudo anal?tico com delineamento transversal, foram recrutadas 10 (dez) mulheres com s?ndrome do ov?rio polic?stico (grupo SOP) e 10 (dez) mulheres com ciclo menstrual normal (grupo controle). As volunt?rias foram avaliadas por uma ficha de avalia??o e pelo exame de ultrassonografia transperineal. O plano axial foi utilizado para avaliar a espessura dos m?sculos levantadores do ?nus no lado direito e do lado esquerdo. A estat?stica descritiva e o teste de Mann Whitney foram utilizados para caracterizar a amostra e para comparar os grupos. Os resultados mostraram que a m?dia de idade foi de 25,1 (? 2,1) e 24,2 (? 1,9) no grupo SOP e controle, respectivamente (p> 0,05). N?o h? diferen?a significativa entre a espessura dos m?sculos do assoalho p?lvico ? direita (Grupo SOP: Direito 1,12 (? 0,5); Esquerda 1,08 (? 0,6) e Controle Grupo: Direito 0,89 (? 0,6); Esquerda 0,94 (? 0,4). Concluiu-se que as mulheres jovens com SOP e ciclo menstrual normal n?o mostram diferen?as na espessura dos m?sculos do assoalho p?lvico identificados pelo ultrassom. No entanto, o grupo com SOP mostrou uma tend?ncia a apresentar uma maior espessura. Talvez, este fato pode ser devido ao estado de hiperandrogenismo ou sobrecarga abdominal. O enriquecimento intelectual e cient?fico ? item indissoci?vel de um Programa de P?s-Gradua??o, por apresentar um perfil multidisciplinar, possibilitou aos alunos um contato diferenciado abrangendo diversos temas da ?rea de sa?de, permitindo ampliar os horizontes acad?micos e cient?ficos e adquirir pensamento cr?tico e anal?tico com senso de responsabilidade. Todas essas caracter?sticas s?o essenciais para influencias o desenvolvimento de pesquisas na ?rea de sa?de, o que exige do pesquisador um conhecimento amplo e t?cnico em diferentes temas. / OBJECTIVE: to evaluate pelvic floor muscle (PFM) thickness in women with polycystic ovary syndrome (PCOS) group and compare it to those with normal menstrual cycle (control group). MATERIALS AND METHODS: transperineal ultrasound examination was used to evaluate the thickness of the bilateral pelvic floor muscles RESULTS: The mean age was 25.1(? 2.1) and 24.2(? 1.9) years in PCOS and control groups, respectively (p> 0.05). Body mass index averaged 22.5(? 0.9) in the control group and 27.8(? 2.6) in the PCOS group (p = 0.03). There was no difference between the thickness of the pelvic floor muscles (PCOS Group: Right 1.12(? 0.5), Left 1.0 (? 0.6) and control group: Right 0.89(? 0.6); Left 0.94(? 0.4)). CONCLUSIONS: there was no differences in pelvic floor muscle thickness identified by ultrasound. However, the PCOS group exhibited a tendency to greater thickness. This may be due to the state of hyperandrogenism or abdominal overload. Intellectual and scientific enrichment is an indissociable item of a Post-Graduation Program, because it presents a multidisciplinary profile, enabled the students to have a differentiated contact covering several health topics, allowing to broaden academic and scientific horizons and acquire critical and analytical thinking with sense of responsability. All these characteristics are essential for influencing the development of health research, which requires the researcher to have a broad and technical knowledge on different topics.

Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2017-07-04T12:09:26Z No. of bitstreams: 1 SamaraAlencarMelo_DISSERT.pdf: 1367781 bytes, checksum: 530b3e8b883b5cad16a54173d6beb00d (MD5) / Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2017-07-11T15:04:08Z (GMT) No. of bitstreams: 1 SamaraAlencarMelo_DISSERT.pdf: 1367781 bytes, checksum: 530b3e8b883b5cad16a54173d6beb00d (MD5) / Made available in DSpace on 2017-07-11T15:04:08Z (GMT). No. of bitstreams: 1 SamaraAlencarMelo_DISSERT.pdf: 1367781 bytes, checksum: 530b3e8b883b5cad16a54173d6beb00d (MD5) Previous issue date: 2016-12-20 / A S?ndrome da Dor Femoropatelar (SDFP), definida como dor anterior ou retropatelar, ? uma das disfun??es m?sculo-esquel?ticas mais frequentes no joelho que acomete, sobretudo, a popula??o feminina e cujo tratamento apresenta-se controverso. Objetivo: Analisar os efeitos imediatos e tardios da aplica??o do Kinesio Taping (KT) na atividade eletromiogr?fica do m?sculo vasto medial obl?quo (VMO), no desempenho isocin?tico do quadr?ceps femoral e na dor de sujeitos portadores da SDFP. M?todos: Ensaio cl?nico, randomizado e cego, no qual 54 volunt?rias, com idade m?dia de 23,70 ? 3,76 anos, foram distribu?das aleatoriamente em tr?s grupos e realizaram um dos seguintes protocolos: (1) grupo controle - permaneceram em repouso; (2) grupo com tens?o - aplica??o do KT com tens?o na regi?o do VMO; (3) grupo sem tens?o - aplica??o do KT sem tens?o, na mesma regi?o. Todas as volunt?rias foram submetidas ? avalia??o da intensidade da dor, da atividade eletromiogr?fica do VMO e VL e dos par?metros dinamom?tricos em tr?s momentos distintos: antes da aplica??o do KT, imediatamente ap?s e 72h depois da aplica??o. A an?lise estat?stica foi realizada por meio do SPSS (vers?o 20.0). Foi utilizada uma ANOVA de modelo misto para verificar diferen?as intra e intergrupo, com n?vel de signific?ncia de 5% (p ? 0,05). Resultados: Houve diferen?a significativa intergrupo na intensidade da dor entre o grupo sem tens?o e o grupo controle, ap?s 72h. Com rela??o ?s vari?veis dinamom?tricas, n?o houve diferen?a entre os grupos avaliados para o pico de torque normalizado pelo peso corporal, pico de torque m?dio, pot?ncia m?dia e trabalho total. Tamb?m n?o foram observadas diferen?as no que se refere ?s vari?veis eletromiogr?fica: raz?o VMO/VL e tempo de in?cio da ativa??o do VMO em rela??o ao VL, em cadeia aberta e fechada. Conclus?o: O Kinesio Taping, aplicado no vasto medial obl?quo, n?o promove altera??es imediatas e nem tardias no desempenho isocin?tico nem nos par?metros eletromiogr?ficos de portadores da S?ndrome da Dor Femoropatelar. Entretanto, foi observada uma redu??o da dor no grupo que aplicou o KT sem tens?o, ap?s 72 horas da sua aplica??o. / Patellofemoral pain syndrome (PFPS) is defined as anterior or retropatellar pain. It is one of the most frequent musculoskeletal dysfunctions in the knee, that affects mainly, the female population and whose treatment is controversial. Objective: To analyze the immediate and late effects of Kinesio Taping (KT) in the electromyography activity of the vastus medialis obliquus (VMO), in the isokinetic performance of the quadriceps femoris and the pain of subjects with PFPS. Methods: Randomized clinical trial, in which 54 volunteers, with a mean age of 23.70 ? 3.76 years were randomized into three groups and performed one of the following protocols: (1) control group - remained in rest; (2) group with tension - application of KT with tension in the VMO region; (3) group without tension - application of KT without tension, in the same region. All volunteers were submitted to the evaluation of pain intensity, electromyography activity of the VMO and the VL and the dynamometric parameters in three different moments: before the application of KT, after the application and 72 hours after the application. Statistical analysis was performed using SPSS (version 20.0). A mixed model ANOVA was used to verify intra and intergroup differences, with a significance level of 5% (p ? 0.05). Results: There was a significant intergroup difference in pain intensity in the 72h evaluation between the no tension group and the control group. Dynamometric variables, peak torque normalized by body weight, mean peak torque, mean power and total work did not show significant difference between the groups evaluated. No differences were observed in the electromyography variables, VMO/ VL ratio and time of onset of VMO activation in relation to VL. Conclusion: Kinesio Taping, applied to the vastus medialis obliquus, does not promote immediate or late changes in the isokinetic performance and in the electromyography parameters of patients with Patellofemoral Pain Syndrome. However, was observed a reduction in pain, in the no tension group after 72 hours of application.

Submitted by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2014-12-18T11:57:11Z No. of bitstreams: 2 camila_danielle_cunha_neves.pdf: 1114741 bytes, checksum: d50be0f18b6b46636a9e4cf8ef159a66 (MD5) license_rdf: 22974 bytes, checksum: 99c771d9f0b9c46790009b9874d49253 (MD5) / Approved for entry into archive by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2014-12-18T12:22:44Z (GMT) No. of bitstreams: 2 camila_danielle_cunha_neves.pdf: 1114741 bytes, checksum: d50be0f18b6b46636a9e4cf8ef159a66 (MD5) license_rdf: 22974 bytes, checksum: 99c771d9f0b9c46790009b9874d49253 (MD5) / Approved for entry into archive by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2014-12-18T12:22:41Z (GMT) No. of bitstreams: 2 camila_danielle_cunha_neves.pdf: 1114741 bytes, checksum: d50be0f18b6b46636a9e4cf8ef159a66 (MD5) license_rdf: 22974 bytes, checksum: 99c771d9f0b9c46790009b9874d49253 (MD5) / Approved for entry into archive by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2014-12-18T12:23:34Z (GMT) No. of bitstreams: 2 camila_danielle_cunha_neves.pdf: 1114741 bytes, checksum: d50be0f18b6b46636a9e4cf8ef159a66 (MD5) license_rdf: 22974 bytes, checksum: 99c771d9f0b9c46790009b9874d49253 (MD5) / Made available in DSpace on 2014-12-18T12:23:37Z (GMT). No. of bitstreams: 2 camila_danielle_cunha_neves.pdf: 1114741 bytes, checksum: d50be0f18b6b46636a9e4cf8ef159a66 (MD5) license_rdf: 22974 bytes, checksum: 99c771d9f0b9c46790009b9874d49253 (MD5) Previous issue date: 2014 / O efeito do consumo cr?nico do cigarro no perfil inflamat?rio, estresse oxidativo e desempenho f?sico t?m sido investigado em fumantes assintom?ticos, contudo, estes estudos na sua maioria ainda s?o poucos e divergentes. Sendo assim, o objetivo deste estudo foi avaliar o efeito cr?nico do tabagismo no perfil inflamat?rio, estresse oxidativo, fun??o muscular esquel?tica perif?rica e aptid?o cardiorrespirat?ria de homens adultos assintom?ticos. Os sujeitos do estudo foram divididos igualmente entre o grupo fumante (GF, n= 20) e grupo controle (GC, n= 20), composto por sujeitos n?o fumantes. A fun??o pulmonar de todos participantes foi avaliada pela espirometria. O perfil inflamat?rio foi avaliado pela mensura??o das concentra??es plasm?ticas das citocinas IL-6, TNF-?, IL-10 e pelos receptores sol?veis de TNF-? (sTNFR1 e sTNFR2). O estresse oxidativo foi avaliado pela mensura??o das concentra??es plasm?ticas das subst?ncias reativas ao ?cido tiobarbit?rico (TBARS), da atividade das enzimas antioxidantes super?xido dismutase (SOD) e catalase de eritr?citos e pela capacidade antioxidante total do plasma. A fun??o muscular esquel?tica perif?rica foi avaliada por meio das medidas de pico de torque dos m?sculos extensores e flexores de joelho e da resist?ncia e fadiga muscular dos m?sculos extensores de joelho; e a aptid?o cardiorrespirat?ria foi avaliada atrav?s da mensura??o do consumo pico de oxig?nio (VO2pico), frequ?ncia card?aca m?xima (FCmax) e dist?ncia caminhada em um teste m?ximo de caminhada/corrida. Sujeitos do GF apresentaram aumentos significativos das concentra??es plasm?ticas de TBARS e do receptor sol?vel sTNFR1 e diminui??es significativas da atividade da enzima catalase em lisado eritrocit?rio, comparados ao GC. Al?m disso, sujeitos do GF exibiram menor resist?ncia muscular dos m?sculos extensores de joelho como determinado pelas medidas de trabalho, com inalterado ?ndice de fadiga dos m?sculos extensores de joelho e pico de torque dos m?sculos extensores e flexores de joelho. A aptid?o cardiorrespirat?ria foi similar entre os sujeitos do GF e do GC. Este estudo demonstrou que homens fumantes cr?nicos e assintom?ticos exibiram altera??es no perfil inflamat?rio, no estresse oxidativo e na fun??o muscular esquel?tica perif?rica, quando comparados a n?o fumantes. / The effect of chronic cigarette smoking on inflammatory profile, oxidative stress and physical performance has been investigated in asymptomatic smokers, however, these studies are few and divergent. Thus, the aim of this study was to evaluate the chronic effect of smoking on inflammatory profile, oxidative stress, peripheral skeletal muscle function and cardiorespiratory fitness in asymptomatic adult men. The subjects of the study were divided equally between the smoking group (SG, n = 20) and control group (CG, n = 20) composed of non-smoking subjects. The lung function of all participants was assessed by spirometry. The inflammatory response was assessed by measurement of plasma concentrations of IL- 6, TNF- ?, IL -10 and soluble receptors for TNF-? (sTNFR1 and sTNFR2). Oxidative stress was evaluated by measuring plasma concentrations of thiobarbituric acid reactive substances (TBARS), the activity of antioxidant enzymes superoxide dismutase (SOD) and catalase in erythrocytes and the total antioxidant capacity of plasma. The peripheral skeletal muscle function was assessed by measuring the peak torque of the extensor and flexor muscles of the knee; and resistance and muscle fatigue of the knee extensor muscles; and cardiorespiratory fitness was assessed by measurement of peak uptake oxygen (VO2peak), maximum heart rate (HRmax) and distance walked on a maximum test of the walk/run. SG subjects showed significant increases in plasma concentrations of TBARS and soluble receptors sTNFR1 and significant decreases in erythrocyte catalase enzyme activity, compared to the CG. In addition, SG subjects exhibited less muscle strength of knee extensors muscles as determined by measures of work and unchanged fatigue index of the knee extensors muscles and peak torque of knee extensors and flexors muscles. Cardiorespiratory fitness was similar between subjects SG and CG. This study demonstrated that male chronic smokers, healthy adult, exhibited changes in the inflammatory response, oxidative stress and peripheral skeletal muscle function, when compared to non-smokers. / Disserta??o (Mestrado) ? Programa Multic?ntrico de P?s-gradua??o em Ci?ncias Fisiol?gicas, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2014.

Submitted by Jos? Henrique Henrique (jose.neves@ufvjm.edu.br) on 2018-03-13T19:28:36Z No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) priscilla_avelino_ferreira_pinto.pdf: 1920663 bytes, checksum: c9bd6e512c60dc9f7254711669d80fe0 (MD5) / Approved for entry into archive by Rodrigo Martins Cruz (rodrigo.cruz@ufvjm.edu.br) on 2018-03-29T11:52:20Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) priscilla_avelino_ferreira_pinto.pdf: 1920663 bytes, checksum: c9bd6e512c60dc9f7254711669d80fe0 (MD5) / Made available in DSpace on 2018-03-29T11:52:21Z (GMT). No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) priscilla_avelino_ferreira_pinto.pdf: 1920663 bytes, checksum: c9bd6e512c60dc9f7254711669d80fe0 (MD5) Previous issue date: 2017 / Funda??o de Amparo ? Pesquisa do Estado de Minas Gerais (FAPEMIG) / Introdu??o: A Distrofia Muscular de Duchenne (DMD) ? marcada pela falta da distrofina, e sua aus?ncia leva a altera??es mec?nicas da fibra muscular, resultando num processo de necrose muscular e altera??es histol?gicas. O treinamento f?sico de baixa intensidade vem sendo empregado como forma de retardar a progress?o da DMD, entretanto, ainda n?o se sabe os par?metros ben?ficos ao m?sculo distr?fico. Assim, objetivou-se elucidar os efeitos do exerc?cio terap?utico de baixa intensidade em esteira no m?sculo esquel?tico distr?fico do modelo mdx nos par?metros morfol?gicos, na morfometria dos marcadores de les?o muscular, da fibrose musclar e na constitui??o da matriz extracelular pelos col?genos tipo I e III. Metodologia: Foram estudados tr?s grupos: camundongos mdx exerc?cio (mdxE), mdx sedent?rio (mdxC) e controle saud?veis (Cc) (n=8/grupo). O grupo mdxE foi estimulado a correr em esteira horizontal motorizada para ratos, em baixa intensidade, 9m/min por 30 minutos/dia, 3 vezes/semana, por 8 semanas. Ap?s o protocolo de exerc?cio foi realizada a eutan?sia dos animais e coletado o m?sculo gastrocn?mio. Foi realizada a colora??o Hematoxilina-Eosina para an?lise dos marcadores de les?o muscular: N?cleo Central e Di?metro M?nimo de Feret; a rea??o de Picrossirius red para an?lise das fibras col?genas na fibrose muscular e a imuno-localiza??o das fibras col?genas tipo I e III. Resultados: Foram observadas altera??es histol?gicas distr?ficas caracter?sticas nos grupos mdxE e mdxC e feixes de fibras col?genas espessas no grupo mdxC. A imuno-histoqu?mica revelou presen?a de col?geno do tipo I principalmente no grupo mdxC. N?o houve diferen?a significativa entre os grupos mdxE e mdxC para fibras com n?cleo central e coeficiente de varia??o do Di?metro m?nimo de Feret. O grupo mdxE n?o apresentou diferen?a significativa em rela??o ao Cc para a porcentagem da ?rea de fibras col?genas na fibrose muscular. Conclus?es: O treino de baixa intensidade reduz a deposi??o de fibras col?genas na fibrose muscular, com fibras delgadas do col?geno tipo I e n?o altera os marcadores de les?o muscular. / Disserta??o (Mestrado Profissional) ? Programa de P?s-Gradua??o em Reabilita??o e Desempenho Funcional, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2017. / Introduction: Duchenne muscular dystrophy (DMD) is marked by lack of dystrophin, and its absence leads to muscle fiber rupture, resulting in muscular necrosis and histological changes. Physical training of low intensity has been used to delay the progression of DMD, however, parameters of the dystrophic muscle are not yet known. The objective of this study was to elucidate the effects of a treadmill low intensity exercise on morphology, morphometric parameters of the muscle injury markers and the composition of the extracellular matrix by type I and III collagens of the dystrophic skeletal muscle of the mdx model. Methods: Three groups were studied: exercised mdx (mdxE), sedentary mdx (mdxC) and healthy controls (Cc) (n =8/group). The mdxE group was stimulated to run on a motorized horizontal treadmill for rats, with a low intensity (9 m/min for 30 minutes/day, 3 times/week) for 8 weeks. After the exercise protocol, the animals were euthanized and the gastrocnemius muscle was collected. Hematoxylin-Eosin staining was performed for analysis of muscle injury markers, Central Nucleus and Minimum Diameter of Feret, Picrossirius red reaction for analysis of collagen fibers in muscle fibrosis and immuno-localization of type I and III collagen fibers. Results: Dystrophic histopathological changes were observed in the mdxE and mdxC groups and thicker collagen fiber bundles in the mdxC group. Immunohistochemistry revealed the presence of type I collagen mainly in the mdxC group. There was no significant difference between the mdxE and mdxC groups for fibers with centrally located nuclei and coefficient of variation of the Minimum Feret Diameter. The mdxE group showed no significant difference in relation to Cc for the percentage of the area of collagen fibers in muscle fibrosis. Conclusions: The low intensity training reduced the deposition of collagen fibers in muscle fibrosis with thin fibers of type I collagen and did not alter the markers of muscle injury.

Made available in DSpace on 2014-12-17T14:13:37Z (GMT). No. of bitstreams: 1 KarynaMOBF.pdf: 5534733 bytes, checksum: 530fbd079356df5078e7d3aeb2952942 (MD5) Previous issue date: 2008-12-16 / This study aimed at assessing the interobserver reliability of the Brazilian-Portuguese version of the Berg Balance Scale (BBS). The assessment was made by physiotherapists with extensive or little clinical experience in non-institutionalized elderly individuals. Participants comprised 12 elderly subjects (10 women and 2 men) with mean ages of 75.8 ? 8.4 years (range = 63-87) and 18 physiotherapists with varying clinical experience. Inter-examiner reliability obtained for each scale item yielded weighted kappa value > 0.75 in 11 of the 14 items (varying from 0.37 to 1.0). The intra-class correlation coefficient (ICC) for the total sum of BBS scores between the two groups of physiotherapists was 0.996 (95% confidence interval, 0.987 0.999) with a Cronbach alpha coefficient of 0.996. We found no difference between the rater groups when we compared the sum score means obtained with the student s T-test (p = 0.86). Although some items had low reliability values, in general our results suggest that the Brazilian Version of the BBS showed good levels of interrater reliability and agreement when used by physiotherapists with different clinical practice levels and without previous training on non-institutionalized elderly patients. We concluded that the BBS can be useful as an important evaluation instrument on a protocol for Rehabilitation clinics. It may be used by various health professionals, as: Physicians, Physical therapists, Physical educators, Occupational therapists, Nurses and Phonoaudiologists, so confirming the interdisciplinary character of this study / O presente trabalho objetivou avaliar a confiabilidade interobservador da Vers?o Brasileira da Escala do Equil?brio de Berg (EEB), entre fisioterapeutas com extensa e escassa pr?tica cl?nica em uma popula??o idosa n?o-institucionalizada. Participaram do estudo 12 idosos (10 mulheres e 2 homens), com m?dia de idade de 75,8 anos ? 8,39 (varia??o de 63-87) e 18 fisioterapeutas com diferentes n?veis de experi?ncia cl?nica. A confiabilidade interexaminador obtida em cada item da escala, apresentou um valor de Kappa ponderado (Kw) de > 0,75 em 11 dos 14 itens (varia??o de 0,37 a 1,0). O coeficiente de correla??o intraclasses (ICC) da soma da pontua??o total da EEB entre os dois grupos de fisioterapeutas foi de 0,996 (IC 95%, 0,987 - 0,999) e com o coeficiente de Cronbach de 0,996. N?o encontramos diferen?as entre os grupos de avaliadores quando comparadas as m?dias da pontua??o total obtida por meio do teste T-student (p=0,86). Embora alguns itens tenham apresentado baixos valores de confiabilidade, em geral nossos resultados sugerem que a Vers?o Brasileira da EEB apresenta bons n?veis de confiabilidade interobservador quando utilizada por fisioterapeutas com diferentes n?veis de pr?tica cl?nica e sem treinamento pr?vio em idosos que vivem na comunidade. Conclu?mos que a EEB pode servir como um importante instrumento de avalia??o dentro de um protocolo sistematizado para servi?os de Reabilita??o, onde sua utiliza??o pode ser realizada por diferentes profissionais de sa?de, tais como: M?dicos, Fisioterapeutas, Educadores f?sicos, Terapeutas ocupacionais, Enfermeiros e Fonoaudi?logos, confirmando assim o car?ter interdisciplinar dessa pesquisa

Made available in DSpace on 2014-12-17T15:16:11Z (GMT). No. of bitstreams: 1 RafaelaSF_DISSERT.pdf: 900361 bytes, checksum: 495352e9755ba95f3abc69208525008d (MD5) Previous issue date: 2010-11-03 / To analyze the effects of electrical stimulation at two frequencies on the EMG parameters (EMG) and dynamometer, in muscles with different typing. MATERIALS AND METHODS: This is a controlled clinical trial, randomized and double blind. Sixty healthy volunteers (23.6 ? 4.2anos; 54.2 ? 7.7kg, 1.62 ? 0.009 cm) of both sexes were divided randomly into three groups: control group (CG), experimental group 1 (SG1) with application of the current Russian 30 HZ and experimental group 2 (EG2) at 70 Hz The volunteers performed an initial assessment (AV1) on the isokinetic dynamometer with three repetitions maximum voluntary isometric (MVC) for knee extension concomitant uptake of EMG for the VM muscle, VL and RF. Later, after application of NMES, they underwent an experimental protocol of isometric fatigue using 70% of MVIC, ending with the completion of a final assessment (AV2) in the same manner as the AV1. RESULTS: By analyzing the profile of the 60 subjects in three broad, VM showed a higher value of RMS behavior when the VL and RF (p = 0.03 and p = 0.02). With respect to Fmed the RF muscle (p = 0.001) showed a higher value for the VM. The VM muscle showed significant increases of Fmed (p = 0.05) after electrical stimulation at 70 Hz when compared the AV1 AV2 and RF showed significant decreases (p = 0.009) after stimulation at 30 Hz during the fatigue showed an increase RMS in the VM and VL, with a reduction in RF. For the variable Fmed was observed in three broad decline during fatigue. CONCLUSION: Our findings provide evidence that the muscles VM, VL and RF fiber typing are different besides indicating that the frequency of NMES tend to relate to the muscle stimulated. Finally suggests the surface EMG as a noninvasive method for characterizing muscle / OBJETIVO: Analisar os efeitos da eletroestimula??o sobre os par?metros eletromiogr?ficos e dinamom?tricos do m?sculo quadr?ceps. MATERIAIS E M?TODOS: Trata-se de um ensaio cl?nico controlado, randomizado e duplo cego. Sessenta volunt?rios saud?veis (23.6?4.2anos; 54.2?7.7Kg; 1,62?0,009cm) de ambos os sexos foram divididos aleatoriamente em tr?s grupos: grupo controle (GC), grupo experimental 1 (GE1) com aplica??o de corrente russa a 30 HZ e grupo experimental 2 (GE2) a 70 Hz. Os volunt?rios realizaram uma avalia??o inicial (AV1) no dinam?metro isocin?tico com 3 repeti??es isom?tricas volunt?rias m?ximas (CIVM), para extens?o do joelho concomitante a capta??o da EMG para os m?sculos vasto medial (VM), vasto lateral (VL) e reto femoral (RF). Posteriormente, ap?s aplica??o da eletroestimula??o neuromusuclar (EENM) foram submetidos a um protocolo experimental de fadiga isom?trica utilizando 70% da CIVM, finalizando com a realiza??o de uma avalia??o final (AV2), nos mesmos moldes da AV1. A an?lise dos dados se deu atrav?s da utiliza??o do programa estat?stico SPSS for Windows (Statistical Packege For the Social Sciense) 17.0 e foram utilizados Anova one way nas compara??es entre os grupos e teste t pareado nas compara??es dentro dos grupos. RESULTADOS: Ao analisar o perfil dos 3 vastos nos 60 sujeitos, o VM apresentou um maior valor de RMS quando comportamento ao VL e RF (p=0,03 e p=0,02). Com rela??o a Fmed, o m?sculo RF (p=0,001) apresentou maior valor comparado ao VM. O m?sculo VM apresentou aumentos significativos da Fmed (p=0,05) ap?s eletroestimula??o a 70 Hz quando a AV1 foi comparada a AV2 e o RF apresentou quedas significativas (p=0,009) ap?s estimula??o a 30 Hz. Durante a fadiga observou-se aumento do RMS no VM e VL, com redu??o no RF. Para a vari?vel Fmed observou-se queda nos tr?s vastos durante a fadiga. CONCLUS?O: Os achados deste estudo sugerem que os m?sculos VM, VL e RF possuem tipagens de fibras diferentes al?m de indicar que as frequ?ncias de EENM tendem a se relacionar com o m?sculo estimulado. Por fim sugere a EMG de superf?cie como um m?todo n?o invasivo para caracteriza??o muscular

Made available in DSpace on 2014-12-17T15:32:29Z (GMT). No. of bitstreams: 1 CassianoFWN_TESE.pdf: 3914655 bytes, checksum: c6fb9bd86bba433eb6a5a047a9337861 (MD5) Previous issue date: 2010-09-23 / Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico / The odontogenic keratocysts are distinguished from other odontogenic cystic lesions by their potentially aggressive clinical behavior and association, in some cases, with Gorlin syndrome. Studies have suggested that syndrome keratocysts, in comparison with sporadic lesions, have higher growth and infiltration capacity and higher recurrence tendency. The aim of this study was to analyze, by means of immunohistochemistry, the expressions of receptor activator of nuclear factor ?B ligand (RANKL) and osteoprotegerin (OPG), the angiogenic index (CD34) and the presence of myofibroblasts (?-SMA) in primary and recurrent sporadic keratocysts and in keratocysts associated with Gorlin syndrome. The sample was composed by 30 sporadic keratocysts (22 primary and 8 recurrent) and 22 syndrome keratocysts. In the epithelium and in the fibrous capsule of the lesions, the immunoexpression of RANKL and OPG was evaluated by determination of the percentage of positive cells, according to the following scores: 0 (less than 10% of positive cells), 1 (11% - 50% of positive cells), 2 (51% - 75% of positive cells) and 3 (more than 76% of positive cells). In addition, cases were classified according to the RANKL score/ OPG score ratio, as follows: RANKL > OPG, RANKL < OPG, and RANKL = OPG. The angiogenic index was analyzed by counting the microvessels immunoreactive to anti-CD34 antibody in 5 fields (200?). The analysis of myofibroblasts was performed by counting the cells immunoreactive to anti-?-SMA antibody in 10 fields (400?). The analysis of the expressions of RANKL and OPG in the epithelial lining and in the fibrous capsule did not reveal significant differences between groups (p > 0.05). Regarding the RANKL/ OPG ratio in the epithelial lining, most sporadic primary (54.5%) and syndrome lesions (59.1%) showed RANKL < OPG ratio and RANKL = OPG ratio, respectively (p > 0.05). With respect to the RANKL/ OPG ratio in the fibrous capsule, the majority of sporadic primary (81.8%) and sporadic recurrent lesions (75.0%) and most syndrome lesions (45.5%) showed RANKL = OPG ratio (p > 0.05). The mean number of microvessels was 69.2 in sporadic primary lesions, 67.6 in recurrent lesions, and 71.6 in syndrome lesions, with no significant differences between groups (p > 0.05). The mean number of myofibroblasts was 34.4 in sporadic primary lesions, 29.3 in recurrent lesions, and 33.7 in syndrome lesions, with no significant differences between groups (p > 0.05). In conclusion, the results of the present study suggest that the differences in the biological behavior between sporadic keratocysts and keratocysts associated with Gorlin syndrome may not be related to the expressions of RANKL and OPG, the RANKL/ OPG ratio, the angiogenic index or the number of myofibroblasts in these lesions / Os ceratocistos odontog?nicos se destacam em rela??o a outras les?es c?sticas odontog?nicas pelo comportamento cl?nico potencialmente agressivo e por se apresentarem associados, em alguns casos, ? s?ndrome de Gorlin. Estudos t?m sugerido que os ceratocistos sindr?micos, em compara??o ?s les?es isoladas, possuem maior capacidade de crescimento e infiltra??o e maior tend?ncia ? recorr?ncia. O objetivo do presente trabalho consistiu em analisar, por meio de imuno-histoqu?mica, as express?es do ligante do receptor ativador do fator nuclear ?B (RANKL) e da osteoprotegerina (OPG), o ?ndice angiog?nico (CD34) e a presen?a de miofibroblastos (?-SMA), em ceratocistos isolados prim?rios e recorrentes e ceratocistos associados ? s?ndrome de Gorlin. A amostra foi composta por 30 ceratocistos isolados (22 prim?rios e 8 recorrentes) e 22 ceratocistos sindr?micos. A express?o de RANKL e OPG foi avaliada no epit?lio e na c?psula fibrosa das les?es, estabelecendo-se o percentual de c?lulas imunopositivas, de acordo com os escores: 0 (? 10% das c?lulas positivas), 1 (11% - 50% das c?lulas positivas), 2 (51% - 75% das c?lulas positivas) e 3 (? 76% das c?lulas positivas). Al?m disso, os casos foram categorizados, segundo a propor??o RANKL/ OPG, em: RANKL > OPG, RANKL < OPG e RANKL = OPG. O ?ndice angiog?nico foi analisado por meio da contagem dos microvasos imunomarcados pelo anticorpo anti-CD34, em 5 campos (200?). Para a avalia??o dos miofibroblastos, foram quantificadas as c?lulas imunorreativas ao anticorpo anti-?-SMA, em 10 campos (400?). A an?lise das express?es de RANKL e OPG, no revestimento epitelial e na c?psula fibrosa, n?o revelou diferen?as significativas entre os grupos (p > 0,05). Em rela??o ? propor??o RANKL/ OPG no revestimento epitelial, grande parte das les?es isoladas prim?rias (54,5%) e sindr?micas (59,1%) exibiu propor??o RANKL < OPG e propor??o RANKL = OPG, respectivamente (p > 0,05). Em rela??o ? propor??o RANKL/ OPG na c?psula fibrosa, a maioria das les?es isoladas prim?rias (81,8%) e isoladas recorrentes (75,0%) e grande parte das les?es associadas ? s?ndrome de Gorlin (45,5%) revelaram propor??o RANKL = OPG (p > 0,05). O n?mero m?dio de microvasos foi de 69,2 nas les?es isoladas prim?rias, 67,6 nas les?es recorrentes e 71,6 nas les?es sindr?micas, sem diferen?as significativas entre os grupos (p > 0,05). A an?lise dos miofibroblastos revelou valores m?dios de 34,4 nas les?es isoladas prim?rias, 29,3 nas les?es recorrentes e 33,7 nas les?es sindr?micas, sem diferen?as significativas entre os grupos (p > 0,05). Em conclus?o, os resultados do presente estudo sugerem que as diferen?as no comportamento biol?gico entre ceratocistos isolados e associados ? s?ndrome de Gorlin podem n?o estar relacionadas ?s express?es de RANKL e OPG, ? propor??o RANKL/ OPG, ao ?ndice angiog?nico ou ? quantidade de miofibroblastos presentes nas les?es