Submitted by Sandra Pereira (srpereira@ufrrj.br) on 2017-05-12T14:19:07Z No. of bitstreams: 1 2010 - Henriqueta Talita Guimar?es Barboza.pdf: 10302674 bytes, checksum: 6daf4f88308c3c733615f0772d6db594 (MD5) / Made available in DSpace on 2017-05-12T14:19:07Z (GMT). No. of bitstreams: 1 2010 - Henriqueta Talita Guimar?es Barboza.pdf: 10302674 bytes, checksum: 6daf4f88308c3c733615f0772d6db594 (MD5) Previous issue date: 2010-03-04 / Twelve heterocyclic dialkylphosphorylhydrazones compounds were synthesized in this work. Dialkylphosphorylhydrazones were obtained through 3 steps of reaction. The first step consists on the synthesis of different dialkylphosphonates obtained by reaction of triethyl phosphate (PCl3) with 3 mols of the corresponding alcohol. The second step occurs by the reaction with dialkylphosphonates synthesized and hydrazine, producing dialkylphosphorylhydrazines. The third and last step is the condensation reaction of these dialkylphosphorylhydrazines with different heterocycle substituted aromatic aldehydes. The analysis of the 1H NMR spectra allowed to observe the stereoisomers E and Z, with the formation of E diastereisomer preferencially. All the compounds were characterized by 1H, 13C and 31P NMR, IR and mass spectroscopy. Tests in vitro with, Alternaria sp., Colletotrichum sp., Fusarium sp. e Fusarium solani, known as patogenic in papaya (Carica papaya L.) were performed in order to confirm if the compounds showed fungicide activity. The substance 6 B was the one with the best performance in the inhibition of all fungal growths. Finally, tests with acetylcholinesterase enzyme indicated that all substances did not inhibit this enzyme. Figure 2 - General structures of dialkylphosphoryhidrazones synthesized. R ? Ethyl; propyl; isopropyl e isobuthyl. X = O, Y, Z e W = CH; X = S, Y, Z e W = CH; X = NH, Y, Z e W = CH; X = NH, Y= CH, Z=CH e W = N; X = CH, Y= N, Z=CH e W = N; / Neste trabalho foram sintetizadas doze (12) novas dialquilfosforilidrazonas heteroc?clicas. Esses compostos foram obtidos utilizando-se tr?s etapas de rea??o. A primeira etapa consiste na s?ntese de diferentes fosfonatos de dialquila, obtidos por meio da rea??o do tricloreto de f?sforo (PCl3) com tr?s mols do ?lcool correspondente. A segunda etapa ocorre por meio da rea??o dos fosfonatos de dialquila sintetizados com a hidrazina, formando as dialquilfosforilidrazinas. A terceira e ?ltima etapa ? a condensa??o destas dialquilfosforilidrazinas com diferentes alde?dos heteroc?clicos. A an?lise dos espectros de RMN-1H indica a forma??o de diastereois?meros, E e Z, com predomin?ncia do diastereis?meros E. Todos os compostos obtidos foram caracterizados por RMN de H1 e C13 e P31, IV, an?lises de massas. Em seguida foram realizados testes in vitro para verificar se os mesmos possuem atividade fungicida sobre os fungos Alternaria sp., Colletotrichum sp., Fusarium sp. e Fusarium solani, conhecidos por serem pat?genos da cultura de mam?o (Carica papaya L.). O composto 6 B foi o que apresentou o melhor efeito fungicida sobre o crescimento de todos os fungos. Finalmente foram realizados testes com a enzima acetilcolinesterase a fim de observar a toxicidade dos compostos sintetizados frente a esta enzima. Figura 1- Estrututa gen?rica das dialquilfosforilidrazonas heteroc?clicas sintetizadas. R ? Etil; propil; isopropil e isobutil. X = O, Y, Z e W = CH; X = S, Y, Z e W = CH; X = NH, Y, Z e W = CH; X = NH, Y= CH, Z=CH e W = N; X = CH, Y= N, Z=CH e W = N.

Made available in DSpace on 2016-06-02T20:23:14Z (GMT). No. of bitstreams: 1 5192.pdf: 7955176 bytes, checksum: 058213922167c7550f42929bb50317d3 (MD5) Previous issue date: 2012-09-20 / Universidade Federal de Minas Gerais / The theme of this work is the film preservation in Brazil and its focus is the film preservation history of Limite (Mário Peixoto, 1931). In the introduction we situate our research within a Brazilian reality of appreciation of academic studies on the preservation of moving images, showing, in advance, some works, produced recently that have become fundamental sources of consultation in our research. In addition to the technical and historical sources, we also present in our bibliographic clipping related to Limite. The origins of our primary sources of research, filmic materials of Limite are also reported in the first lines of our work. In the first chapter of our work we try to approach the field of audiovisual archiving reader, describing each of the technical terms and concepts relevant to the preservation and restoration of audiovisual used throughout the text. In the second chapter, we give an account of contemporary Limite production years, and also of his rare nitrate copy views. The third chapter addresses issues related to the process of restoring physical chemistry of Limite s filmic materials, demand created by precarious conditions presented by the nitrate copy of the film, extending up to the purchase of materials and direct films on the work by Embrafilme, in 1980. The fourth chapter presents and analyzes some stretches of finegrain print, masters and master copy examined during our research, creating the necessary conditions to draw some conclusions about the handling incurred by work, dating from 1930 until 1980. / O tema deste trabalho é a preservação de filmes no Brasil e o seu foco é a história da preservação do filme Limite (Mário Peixoto, 1931). Na introdução procuramos situar nossa pesquisa dentro de uma realidade brasileira de valorização de estudos acadêmicos sobre o universo da preservação das imagens em movimento, apresentando, de antemão, algumas obras, produzidas recentemente que se tornaram fontes fundamentais de consulta em nossa pesquisa. Além das fontes técnicas e históricas, procuramos também, apresentar na introdução nosso recorte bibliográfico relacionado a Limite. As origens de nossas fontes primárias de pesquisa, os materiais fílmicos de Limite, também são informadas nas primeiras linhas de nosso trabalho. No primeiro capítulo de nosso trabalho procuramos aproximar o leitor do campo da arquivística audiovisual, descrevendo cada um dos termos técnicos e conceitos pertinentes à preservação e restauração audiovisuais utilizados ao longo do texto. No segundo capítulo, procuramos dar conta dos anos contemporâneos à produção de Limite, e também de suas raras exibições em cópia nitrato. O terceiro capítulo aborda questões relacionadas ao processo de restauração físico-química dos materiais fílmicos de Limite, demanda criada pelas condições precárias apresentadas pela cópia em nitrato do filme, estendendo-se até à compra dos materiais fílmicos e dos diretos sobre a obra pela Embrafilme, em 1980. O quarto capítulo apresenta e analisa alguns trechos do contratipo, másteres e cópia máster examinados durante nossa pesquisa, criando as condições necessárias para tirarmos algumas conclusões sobre as manipulações sofridas pela obra, datadas desde 1930 até 1980.

Made available in DSpace on 2014-12-17T14:03:42Z (GMT). No. of bitstreams: 1 JoseEGJ.pdf: 604842 bytes, checksum: a34879bd40606d248f800a49ed111824 (MD5) Previous issue date: 2006-12-06 / This report shows 2232 times purification of a βNAcetylhexosaminidase from hepatic extracts from the sea mammal Sotalia fluviatilis homogenate with final recovery of 8,4%. Sequenced steps were utilized for enzyme purification: ammonium sulfate fractionation, Biogel A 1.5 m, chitin, DEAESepharose and hydroxyapatite chromatographies. The protein molecular mass was estimated in 10 kDa using SDSPAGE and confirmed by MALDITOF. It was found to have an optimal pH of 5.0 and a temperature of 60?C. Using pnitrophenylNAcetylβDglycosaminide apparent Km and Vmax values were of 2.72 mM and 0.572 nmol/mg/min, respectively. The enzyme was inhibited by mercury chloride (HgCl2) and sodium dodecil sulfate (SDS) / Este trabalho mostra a purifica??o de 2232 vezes de uma βNAcetilhexosaminidase obtida a partir dos extratos hep?ticos do mam?fero marinho Sotalia fluviatilis com recupera??o final de 8,4%. Passos seq?enciais foram utilizados para a purifica??o enzim?tica: fracionamento com sulfato de am?nio e as cromatografias de Biogel A 1.5 m, Quitina, DEAESepharose e Hidroxiapatita. A massa molecular prot?ica foi estimada em 10 kDa usando SDSPAGE e confirmada por MALDITOF. Foi encontrado como pH e temperatura ?timos, 5,0 e 60?C, respectivamente. Os valores de Km e Vm?x aparentes foram 2,72 mM e 0,572 nmol/mg/min, sendo utilizado o pnitrofenilNAcetilβDglicosamin?deo como substrato. A enzima foi inibida pelo cloreto de merc?rio (HgCl2) e dodecil sulfato de s?dio (SDS)

>Magister Scientiae - MSc / An analysis of South African school mathematics results indicates that one of the problem areas in the mathematical performance of learners is proof and proving. In an endeavour to improve the mathematical proving ability of first year students at UWC, the MAM 112 class (a first year elective mathematics course) was taught a course in elementary logic. In the initial part of the study, logic puzzles were utilized as a tool to teach students to make logical connections between and from mathematical statements using the rules of inference. Subsequently research was done to determine if knowledge and understanding of logic would translate into improved proving abilities of students. To put proof and proving into perspective the origins and functions of proof was explicated and proving in South African schools was investigated. Consequently reasons are advanced for the dismal high school mathematics results in terms of proof and possible solutions are discussed. Recent discoveries of neuroscience are utilized to delineate the brain structures and cognitive processes involved in learning so as to gain a better understanding of the learning of mathematics. The findings of neuroscience, cognitive psychology and educational psychology are employed to elucidate the influence of emotion, confidence, experience and practice on the learning of mathematics in order to determine which factors can be applied to improve the proving abilities of students. The findings of the study indicate that knowledge of logic does help to improve the ability of students to make logical connections (deductions) between and from statements. The results of the study, however, do not indicate that knowledge and understanding of logic translates into improved proving ability of mathematical statements by students.

The doctoral thesis is thematically focused to human operator systems significantly contributing to this system reliability and safety. The theoretical part of the thesis is concerned with human activities and communications in MMS system, valuation and estimation of human reliability probability in MSS. The important part of the thesis is also a description of human operator neuromuscular system as an executive powerful system on MMS system regulating activities and the summary of human driver models in compensative lateral car control. The practical part of the doctoral thesis is based on analyses created by experimental data of drives. Experimental drives were done on drivers set following different backgrounds and different sleep deprivation at whole day. All experimental data was realized from the cooperation and following the agreement of Faculty of Transportation Science research centre on Prague ČVUT. Another part of thesis includes driver simulation model proposals with nonlinear components for lateral car control. Simulation model drives are compared with real drives or drivers on drive-simulator and there are monitored identical and different dynamic movement characteristics. The main target of doctoral thesis is to detect and obtain significant dynamical drive experience characteristics based on experimental data analyses. As well to found drive characters variability owing to driver’s fatigue and determinated evaluated characteristics changes. Acquired results of thesis should help in assistant systems that in cooperation with other components alert to micro-sleep and run off drive possibility.

As industries are transitioning towards mass customisation, manufacturers are looking for alternative techniques that can support the need for a more innovative, flexible, and sustainable production process. One such technique that is currently gaining a lot of momentum is Additive Manufacturing (AM). AM can achieve more complex structures and geometries which in turn makes it possible for highly customised designs with greater efficiency and sustainability. However, despite all the advantages of AM, adoption rates are still low compared to industry predictions, thus some challenges need to be addressed. This paper aims to study the implementation of metal additive manufacturing (MAM) by comparing literature with a real-world example, i.e., a case study at Saab, in an effort to answer the research question: Why adopt MAM; what are the challenges to a successful implementation of MAM; and how can they be overcome? The main theories that have been analysed in this study are Diffusion of Innovation (DOI), Technology-Organisation-Environment (TOE) and Change Management. Which are believed to be essential for understanding the implementation process of new technology.  The thesis follows a qualitative research approach where a single case study was carried out to be able to conduct a more in-depth analysis of the research topic.  In the case study it was identified that key challenges for Saab in implementing MAM are related to Knowledge gaps (both internal and external, partly due to immature technology); Organisational (structural and cultural) and Materials (qualification and standardisation) These key challenges, as identified in the interviews with Saab, match the challenges found in literature where they are described as Knowledge/technical know-how challenges, Organisational challenges, Integration challenges and Standardisation/qualification challenges. In conclusion, the reason to adopt MAM for the case company, a producer of parts with high requirements on functionality and optimization, is the strategic importance due to the technology enabling architectural innovation. The main challenges are related to the organisation and product development process, both in part due to knowledge challenges. In overcoming the challenges to the implementation, it is believed that increased internal and external collaboration is important as a way of generating and developing knowledge and at the same time using the resources more efficiently. Also, the need for re-designing the product development process to become cross-functional and include the whole system to enable architectural innovation.

Submitted by SBI Biblioteca Digital (sbi.bibliotecadigital@puc-campinas.edu.br) on 2017-04-07T19:37:44Z No. of bitstreams: 1 ELIZABETH BROWN VALLIM BRISOLA.pdf: 1755411 bytes, checksum: 14e7e25a069f401ef775a5d9ce3844f5 (MD5) / Made available in DSpace on 2017-04-07T19:37:44Z (GMT). No. of bitstreams: 1 ELIZABETH BROWN VALLIM BRISOLA.pdf: 1755411 bytes, checksum: 14e7e25a069f401ef775a5d9ce3844f5 (MD5) Previous issue date: 2017-02-14 / Research studies that address mothers singing focus on investigating how and why songs facilitate mother-infant communication considering, especially, the acoustical and sociocultural aspects involved. This qualitative and exploratory research study was developed based on Edmund Husserl?s phenomenology and guided by principles of Humanistic psychology, specifically Carl Roger?s Person Centered Approach. It aimed to apprehend the experience of 13 mothers who gave birth to their first child during the past 18 months, about the meaning of singing to their infants. The researcher spoke to each of the participants, all with a college education, during a dialogical encounter, and immediately afterwards wrote a comprehensive narrative to register her comprehension regarding that mother?s experience, based on her own impressions. A narrative-synthesis and a creative synthesis were constructed based on the narratives to enable a phenomenological process of analysis that presupposes three phases: description, comprehension and interpretation of the experience. The structural elements that emerged from the mothers' experience of singing to their infants are: (a) a means of communication hugging their infant with their song; (b) the establishment of an emotional bond with their infant; (c) a way to better know their infant as it develops; (d) a means of recognizing themselves as mothers; (e) a form of sharing personal values and family customs; (f) a creative way of expressing themselves, and (g) a possibility of personal growth. The meaning of this experience enables further reflections regarding human relationships from a psychological viewpoint and can stimulate dialogues with other areas of knowledge. / Las pesquisas que abordan el canto materno se preocupan en investigar c?mo y por qu? las canciones son facilitadoras de la comunicaci?n madre-beb?, dando atenci?n principalmente a los aspectos ac?sticos y socioculturales. Esta pesquisa, cualitativa y de naturaleza exploratoria, fue desarrollada con base en la fenomenolog?a de Edmund Husserl y en orientaciones te?ricas de la psicolog?a humanista, m?s espec?ficamente del Enfoque Centrado en la Persona, de Carl Rogers. Su foco fue aprender de la experiencia de 13 madres que tuvieron su primer hijo en los ?ltimos 18 meses sobre el sentido de cantarle a su beb?. La investigadora convers? com cada participante, mujeres universitarias, durante un encuentro dial?gico, y escribi?, de inmediato, una narrativa comprensiva para registrar su comprensi?n sobre la experiencia de aquella madre a partir de sus propias impresiones. Una s?ntesisnarrativa y una s?ntesis creativa fueron construidas a partir del conjunto de narrativas de manera que sea posible concluir el proceso de an?lisis fenomenol?gico que supone tres fases: descripci?n, comprensi?n e interpretaci?n de la experiencia. Los elementos estructurales que emergieron de las vivencias de las madres sobre cantarles a sus beb?s son: (a) un modo de comunicarse abrazando al beb? con sus sonidos; (b) la construcci?n de un v?nculo; (c) una forma de conocer mejor a su beb? a medida que ?ste se desarrolla; (d) un reconocimiento de s? misma como madre; (e) una manera de transmitir valores personales y costumbres familiares; (f) un modo creativo de expresarse; e (g) la posibilidad de crecimiento personal. El sentido de esta experiencia posibilita nuevas reflexiones sobre el tema de la relaci?n humana en t?rminos psicol?gicos y puede estimular interlocuciones con otras ?reas de conocimiento. / As pesquisas que abordam o cantar materno preocupam-se em investigar como e por que as can??es s?o facilitadoras da comunica??o m?e-beb?, dando aten??o principalmente aos aspectos ac?sticos e socioculturais. Esta pesquisa, qualitativa e de natureza explorat?ria, foi desenvolvida com base na fenomenologia de Edmund Husserl e em norteadores te?ricos da psicologia humanista, mais especificamente da Abordagem Centrada na Pessoa, de Carl Rogers. Objetivou apreender a experi?ncia de 13 m?es que tiveram seu primeiro filho nos ?ltimos 18 meses sobre o sentido de cantar para seu beb?. A pesquisadora conversou com cada uma das participantes, todas com forma??o universit?ria, durante um encontro dial?gico, e escreveu, em seguida, uma narrativa compreensiva para registrar sua compreens?o sobre a experi?ncia daquela m?e a partir de suas pr?prias impress?es. Uma narrativa-s?ntese e uma s?ntese criativa foram constru?das a partir do conjunto de narrativas de forma a possibilitar concluir o processo de an?lise fenomenol?gica que sup?e tr?s fases: descri??o, compreens?o e interpreta??o da experi?ncia. Os elementos estruturais que emergiram das viv?ncias das m?es sobre cantar para seu beb? s?o: (a) um modo de comunicar-se abra?ando o beb? com seus sons; (b) a constru??o de um v?nculo; (c) uma forma de conhecer melhor seu beb? ? medida que ele se desenvolve; (d) um meio de reconhecer a si mesma como m?e; (e) uma maneira de transmitir valores pessoais e costumes familiares; (f) um modo criativo de expressar-se; e (g) a possibilidade de crescimento pessoal. O sentido desta experi?ncia possibilita novas reflex?es sobre o tema do relacionamento humano em termos psicol?gicos e pode estimular interlocu??es com outras ?reas de conhecimento.