O presente trabalho refere-se ao desenvolvimento de grânulos a partir de produto seco de A. satureioides obtido por spray drying, em escala semi-industrial, visando a superar as principais limitações tecnológicas apresentadas tais como a higroscopia excessiva do produto, baixa densidade, pequeno tamanho de partícula e instabilidade dos constituintes flavonoídicos frente à luz. Dois métodos foram empregados para a granulação: granulação em leito fluidizado e granulação via seca por desagregação. Estes métodos apresentaram, respectivamente, 15 e 60 % de rendimento do processo, levando a escolha da granulação seca para a produção dos grânulos do produto seco. A granulação seca resultou em grânulos assimétricos, de faixa granulométrica situada entre 0,3 mm e 1,9 mm e de superfície irregular e rugosa. O revestimento destes grânulos foi realizado em leito fluidizado, utilizando três tipos de polímeros, Eudragit® L 30D, Opadry® II e Opadry® AMB.O rendimento médio com o Opadry® II foi de 72 %. O revestimento com Opadry® AMB foi realizado utilizando-se um baixo e alto fluxo do líquido de revestimento, obtendo-se rendimentos de 75 e 85 %, respectivamente. A higroscopia dos grânulos foi avaliada em ambientes com umidade relativa controlada de 65 ou 99 %, comparando-se o comportamento dos grânulos revestidos com o dos grânulos sem a presença de revestimento. Ambos os filmes com Opadry® não protegeram os grânulos frente à umidade. As fotomicrografias por MEV, destes grânulos, revelaram que, ambos os tipos de revestimento, apresentaram superfícies rugosas e com presença de poros explicando, parcialmente, a falta de proteção contra a umidade. O estudo da fotoproteção indica, em um primeiro momento, que o filme de revestimento promove a proteção dos flavonóides frente a ação da luz. A avaliação preliminar da liberação dos flavonóides, a partir dos grânulos, foi realizada em células de fluxo Desaga® com os grânulos sem revestimento e revestidos com Opadry® AMB. A água não demonstrou ser o meio mais favorável para este ensaio. Em meio com pH 1,2 contendo 1 % de laurilsulfato de sódio, os flavonóides quercetina, luteolina e 3-Ometilquercetina foram liberados, respectivamente, após 90 minutos, em 70, 83 e 70 % a partir dos grânulos não revestidos, e 52, 54 e 45 % a partir dos grânulos revestidos com Opadry® AMB, denotando a influência do filme de revestimento sobre o perfil de liberação dos flavonóides. Em seu conjunto, os resultados obtidos nesta primeira abordagem deste tema abrem diversas perspectivas para oaprofundamento do estudo e desenvolvimento de granulados de A. satureioides, a partir de produto seco por spray drying. / The present work was designed to develop granules from Achyrocline satureioides spray dried powders in order to overcome the main technological limitations presented by this herbal raw material: high hygroscopy, low density, small particle diameter and flavonoid sensibility against light. Two methods were employed for granulation, fluidized bed and dry granulation. These methods presented, respectively, 15 and 60 % of process yield, leading to the selection of dry granulation for preparing the granules. By this method, the granules showed 0,3 to 1,9 mm particle mean diameter, rough surface and irregular morphology. For coating the granules, three types of polymers were employed, Eudragit® L30D, Opadry® II and Opadry® AMB, in fluidized bed. The first one resulted in atomizer obstruction becoming non viable its employment. The mean yield coating obtained with Opadry® II was 72 %. The Opadry® AMB was sprayed in low and high rates yielding, respectively, 75 % and 85 %. The hygroscopicity of the granules was evaluated in controlled conditions of 65 % or 99 % RH, comparing the behavior of the coated granules which that presented by non-coated particles. Both Opadry® coatings did not protect the granules against the humidity. The SEM photomicrographis of these granules revealed that both types of coating presented rough and porous surface explaining partially, at least, the lack of protection against the humidity. The preliminary photostability assay indicated, in a first view, that the coating promotes the flavonoid protection. The flavonoid release from the granules was performed in Desaga® flow cell from the non-coated granules and from Opadry® AMB coated granules. Water demonstrated not to be an appropriate media for both tested granules. In pH 1.2 media containing 1 % of sodium lauryl sulfate, the flavonoids quercetin, luteolin and 3-O-methylquercetin were, respectively, released, after 90 minutes, in 70 %, 83 % and 70 % from non coated granules and in 52 %, 54 % and 45 % from Opadry® AMB coated granules, denoting the influence of the coating on the flavonoid release profile. Taken together, the results of this first approach openmay perspectives for more detailed studies on Achyrocline satureioides granules from the corresponding spray dried powders.

O presente trabalho refere-se ao desenvolvimento de grânulos a partir de produto seco de A. satureioides obtido por spray drying, em escala semi-industrial, visando a superar as principais limitações tecnológicas apresentadas tais como a higroscopia excessiva do produto, baixa densidade, pequeno tamanho de partícula e instabilidade dos constituintes flavonoídicos frente à luz. Dois métodos foram empregados para a granulação: granulação em leito fluidizado e granulação via seca por desagregação. Estes métodos apresentaram, respectivamente, 15 e 60 % de rendimento do processo, levando a escolha da granulação seca para a produção dos grânulos do produto seco. A granulação seca resultou em grânulos assimétricos, de faixa granulométrica situada entre 0,3 mm e 1,9 mm e de superfície irregular e rugosa. O revestimento destes grânulos foi realizado em leito fluidizado, utilizando três tipos de polímeros, Eudragit® L 30D, Opadry® II e Opadry® AMB.O rendimento médio com o Opadry® II foi de 72 %. O revestimento com Opadry® AMB foi realizado utilizando-se um baixo e alto fluxo do líquido de revestimento, obtendo-se rendimentos de 75 e 85 %, respectivamente. A higroscopia dos grânulos foi avaliada em ambientes com umidade relativa controlada de 65 ou 99 %, comparando-se o comportamento dos grânulos revestidos com o dos grânulos sem a presença de revestimento. Ambos os filmes com Opadry® não protegeram os grânulos frente à umidade. As fotomicrografias por MEV, destes grânulos, revelaram que, ambos os tipos de revestimento, apresentaram superfícies rugosas e com presença de poros explicando, parcialmente, a falta de proteção contra a umidade. O estudo da fotoproteção indica, em um primeiro momento, que o filme de revestimento promove a proteção dos flavonóides frente a ação da luz. A avaliação preliminar da liberação dos flavonóides, a partir dos grânulos, foi realizada em células de fluxo Desaga® com os grânulos sem revestimento e revestidos com Opadry® AMB. A água não demonstrou ser o meio mais favorável para este ensaio. Em meio com pH 1,2 contendo 1 % de laurilsulfato de sódio, os flavonóides quercetina, luteolina e 3-Ometilquercetina foram liberados, respectivamente, após 90 minutos, em 70, 83 e 70 % a partir dos grânulos não revestidos, e 52, 54 e 45 % a partir dos grânulos revestidos com Opadry® AMB, denotando a influência do filme de revestimento sobre o perfil de liberação dos flavonóides. Em seu conjunto, os resultados obtidos nesta primeira abordagem deste tema abrem diversas perspectivas para oaprofundamento do estudo e desenvolvimento de granulados de A. satureioides, a partir de produto seco por spray drying. / The present work was designed to develop granules from Achyrocline satureioides spray dried powders in order to overcome the main technological limitations presented by this herbal raw material: high hygroscopy, low density, small particle diameter and flavonoid sensibility against light. Two methods were employed for granulation, fluidized bed and dry granulation. These methods presented, respectively, 15 and 60 % of process yield, leading to the selection of dry granulation for preparing the granules. By this method, the granules showed 0,3 to 1,9 mm particle mean diameter, rough surface and irregular morphology. For coating the granules, three types of polymers were employed, Eudragit® L30D, Opadry® II and Opadry® AMB, in fluidized bed. The first one resulted in atomizer obstruction becoming non viable its employment. The mean yield coating obtained with Opadry® II was 72 %. The Opadry® AMB was sprayed in low and high rates yielding, respectively, 75 % and 85 %. The hygroscopicity of the granules was evaluated in controlled conditions of 65 % or 99 % RH, comparing the behavior of the coated granules which that presented by non-coated particles. Both Opadry® coatings did not protect the granules against the humidity. The SEM photomicrographis of these granules revealed that both types of coating presented rough and porous surface explaining partially, at least, the lack of protection against the humidity. The preliminary photostability assay indicated, in a first view, that the coating promotes the flavonoid protection. The flavonoid release from the granules was performed in Desaga® flow cell from the non-coated granules and from Opadry® AMB coated granules. Water demonstrated not to be an appropriate media for both tested granules. In pH 1.2 media containing 1 % of sodium lauryl sulfate, the flavonoids quercetin, luteolin and 3-O-methylquercetin were, respectively, released, after 90 minutes, in 70 %, 83 % and 70 % from non coated granules and in 52 %, 54 % and 45 % from Opadry® AMB coated granules, denoting the influence of the coating on the flavonoid release profile. Taken together, the results of this first approach openmay perspectives for more detailed studies on Achyrocline satureioides granules from the corresponding spray dried powders.

Gender violence in Mexico is a problem that affects its society on a long- term basis. Its most extreme form known as feminicide, that is a gender- based murder of women, appears with so much frequency that it can be considered a structural problem yet. Mexico is one of the countries with most cases in Latin America, however, insufficient and ineffective measures taken by the state facilitate their perpetration which is often immune from prosecution. This thesis aims to approximate the issue to the reader and explain the concept of feminicide in given context within its complexity. For that purpose, a process tracing analysis of two selected cases is done; starting from their perpetration to their sentencing by judicial instances. The sentences of both cases became very important milestones. The factors that contributed to the outcome are tracked and afterwards a comparison of tracked causal mechanisms is done. As it was already mentioned, the cases were not selected randomly. Not only are they important for their sentences, but moreover they took place in two Mexican states with traditionally high numbers of committed feminicides, that is in Chihuahua and Mexico State. The results of the analysis suggest that even though Mexico has signed the most important international conventions about women's...

This study explores the intersection of the philosophy of Martin Heidegger and Spanish literature. The study examines the Heideggerian authenticity and inauthenticity of two characters in the literature: Melibea in La Celestina by Fernando de Rojas and Grisóstomo in Don Quijote de la Mancha by Miguel de Cervantes. Heidegger’s concept of authenticity is the ability of the individual to live in the world according to her own desires, outside of the influence of others. Both die by suicide, but Melibea is an authentic character in Heideggerian terms and Grisóstomo is inauthentic. At the end of her life, Melibea has resolved all anxiety into resoluteness and is determined to live life in her own terms. Grisóstomo, however, dies inauthentically, full of anxiety and subject to the will of Others. He never leaves the influence of others to live a life of his own determination.

This thesis examines the intersection between lithium extraction and contemporary art through a visual semiotic analysis of three contemporary artworks: Unknown Fields’ We Power Our Future With the Breast Milk of Volcanoes, Marcela Magno’s Land [2] Litio, and Julian Charrière’s Future Fossil Spaces. It explores how lithium extraction is visualised in the selected artworks, what connotations can be extracted from them, the geopolitical dimension expressed in them, and how they relate to the myth of ‘green’ transition. This text takes a starting point in the notion of critical visualisations of extractivism in contemporary art as an urgent political, artistic, and ecological issue. Extractivism is a crucial concept in this thesis, and it is further explored through the intersection of art and extractivism in dialogue with previous research by, for example, Eray Çaylı, Macarena Gómez-Barris, and T.J. Demos. The artworld’s interest in lithium has grown in the last years, with cultural projects and exhibitions on lithium taking place in Sweden and the Netherlands, yet there are no academic texts that explore the intersection of lithium extraction and contemporary art. The aim of this thesis is to thoroughly examine this intersection through three contemporary artworks, to expand academic literature regarding this topic, but also to make the results available to curators, cultural workers, and artists who are currently developing cultural projects around lithium and its extraction. The results of the visual semiotic analysis demonstrated that all three of the artworks critically engaged with lithium extraction by visibilising either present or future green sacrifice zones. They all countered the myth of ‘green’ transition with different strategies: by showing the two-furthermost-apart links in the lithium supply chain, by recuperating Indigenous creation myths of the extracted landscapes, and by exploring the supposed intangibility of our ever-expanding digital world.

This doctoral dissertation is a study of three works: Marcela Serrano’s novel We Who Love Us So Much (1992), Ariel Dorfman’s play Death and the Maiden (1992) and its filmic version directed by Roman Polanski, and the documentary directed by Maria Elena Wood, The General’s Daughter (2006). Through the representations of subjectivist female characters in the works, we analyze what we call the vicissitudes of female identity in relation to the agitated sociopolitical circumstances that Chile lived from the sixties to 2006. In those decades, we observe the process of the construction of a revolutionary identity that culminates with the election of the Popular Unity government (1970-1973). Then, we examine the breakdown of female revolutionary identity during the violent repression known as the military dictatorship (1973-1990) after the coup d’état. Finally, we investigate the reconstitution of the identity of the women on the political left, a process assumed independently (rather than collectively) by women of varied characteristics and political orientations during the re-democratization period and until 2006. By analysing the female characters moving in literature, theatre, and film, we observe that these characterizations have helped to inform the readers/viewers through sharing stories of women, their limitations, their personal and collective visions presenting their doubts and fears on matters pertaining to them as female entities. But the greatest finding in this study is to discover that cultural products contain a number of female characters that can overcome their limitations in fiction, as is the case for women working in public spaces such as Michelle Bachelet, a “historical character” from The General's Daughter. They are firmly committed to the reality of women’s lives in Chile and deliver an optimistic message; women must continue integrating other women in order to end the discrimination that still exists in Chile.

This doctoral dissertation is a study of three works: Marcela Serrano’s novel We Who Love Us So Much (1992), Ariel Dorfman’s play Death and the Maiden (1992) and its filmic version directed by Roman Polanski, and the documentary directed by Maria Elena Wood, The General’s Daughter (2006). Through the representations of subjectivist female characters in the works, we analyze what we call the vicissitudes of female identity in relation to the agitated sociopolitical circumstances that Chile lived from the sixties to 2006. In those decades, we observe the process of the construction of a revolutionary identity that culminates with the election of the Popular Unity government (1970-1973). Then, we examine the breakdown of female revolutionary identity during the violent repression known as the military dictatorship (1973-1990) after the coup d’état. Finally, we investigate the reconstitution of the identity of the women on the political left, a process assumed independently (rather than collectively) by women of varied characteristics and political orientations during the re-democratization period and until 2006. By analysing the female characters moving in literature, theatre, and film, we observe that these characterizations have helped to inform the readers/viewers through sharing stories of women, their limitations, their personal and collective visions presenting their doubts and fears on matters pertaining to them as female entities. But the greatest finding in this study is to discover that cultural products contain a number of female characters that can overcome their limitations in fiction, as is the case for women working in public spaces such as Michelle Bachelet, a “historical character” from The General's Daughter. They are firmly committed to the reality of women’s lives in Chile and deliver an optimistic message; women must continue integrating other women in order to end the discrimination that still exists in Chile.

This doctoral dissertation is a study of three works: Marcela Serrano’s novel We Who Love Us So Much (1992), Ariel Dorfman’s play Death and the Maiden (1992) and its filmic version directed by Roman Polanski, and the documentary directed by Maria Elena Wood, The General’s Daughter (2006). Through the representations of subjectivist female characters in the works, we analyze what we call the vicissitudes of female identity in relation to the agitated sociopolitical circumstances that Chile lived from the sixties to 2006. In those decades, we observe the process of the construction of a revolutionary identity that culminates with the election of the Popular Unity government (1970-1973). Then, we examine the breakdown of female revolutionary identity during the violent repression known as the military dictatorship (1973-1990) after the coup d’état. Finally, we investigate the reconstitution of the identity of the women on the political left, a process assumed independently (rather than collectively) by women of varied characteristics and political orientations during the re-democratization period and until 2006. By analysing the female characters moving in literature, theatre, and film, we observe that these characterizations have helped to inform the readers/viewers through sharing stories of women, their limitations, their personal and collective visions presenting their doubts and fears on matters pertaining to them as female entities. But the greatest finding in this study is to discover that cultural products contain a number of female characters that can overcome their limitations in fiction, as is the case for women working in public spaces such as Michelle Bachelet, a “historical character” from The General's Daughter. They are firmly committed to the reality of women’s lives in Chile and deliver an optimistic message; women must continue integrating other women in order to end the discrimination that still exists in Chile.

The objectives of the submitted diploma work are to give an overview of the therapeutics{\crq} psychotherapy styles and their feelings about the psychotherapy in general. The work also shows the circumstances which directed them to be the therapeutics. In connection with that the work analyzes also the evolution and, above all, the present situation in the psychotherapy in the Czech Republic. Finally the work summarizes therapeutics{\crq} opinion about the integration in the psychotherapy according to the style they practicing. Theoretical part of the diploma work introduces twelve psychotherapy styles which are commonly use in the Czech Republic. All styles are presented by short historical development and the practical application in our country. Information for the practical part of the diploma work were obtained by interviewing the therapeutics, the interviews were recorded, consequently rewrote and authorized by the therapeutics. The main contribution of the diploma work is the comparison of the therapeutics{\crq} opinions, partly consistent but some time also very different, what is appeared in the interviews. The interviews it self were spitted to the four groups, according to the topics: Knowledge and experiences of the therapist, Common active factors and the efficiency in the psychotherapy, Integration in the psychotherapy and Critique of the psychotherapy.