Made available in DSpace on 2016-07-18T17:53:16Z (GMT). No. of bitstreams: 1 ronaldo sena e silva.pdf: 758805 bytes, checksum: 50ddd870dfedb208e155053c6ec67166 (MD5) Previous issue date: 2015-09-24 / The aim of this study was to verify the use of growth hormone (GH), with or without resisted exercise, the estrous cycle, the dosage of the estradiol and progesterone and Wistar rats endometrium thickness. The rats were divided into four groups (n = 10): CT (Control); Ex (resisted exercise - water jumps with 50% of body weight); GH (0,2UI / kg administered GH); and ExGH (GH and Ex groups combined treatment). The estrous cycle phase of rats were determined by vaginal cytology, daily for 29 days. The rats plasma was used for hormone dosage and the endometrium thicknesses were evaluated by histology. We used the Shapiro-Wilk normality presupposition. For samples that was parametric, ANOVA was used with Tukey, for no parametric samples, Kruskal-Wallis with Student-Newman-Keuls test was used (p<0.05). There are a greater reproductive cycles number in CT than in other groups during the 29 days period (p>0.05), no difference were found between the hormones dosage groups neither endometrial thickness. Therefore, it is concluded that GH and resisted exercises both combined affect females reproductive cycle, they reduced the number of cycles of rats but they do not change the estradiol and progesterone concentrations, neither endometrial thickness. / O objetivo deste estudo foi verificar o uso do hormônio do crescimento (GH), associado ou não ao exercício resistido, no ciclo estral, na dosagem do estradiol e progesterona e na espessura do endométrio de ratas Wistar. As ratas foram divididas em 4 grupos (n=10): CT (controle); Ex (exercício resistido - saltos em água com 50% do peso corporal); GH (0,2UI/Kg de GH administrado); e ExGH (tratamento combinado dos grupos GH e Ex). A fase do ciclo estral foi determinada por citologias vaginais nas ratas, diariamente, durante 29 dias. Foi realizado dosagem hormonal nas ratas e as espessuras dos endométrios foram avaliadas por histologia. Utilizou-se o pressuposto de normalidade de Shapiro-Wilk. Para as amostras paramétricas, utilizou-se ANOVA e Tukey e para não paramétricas Kruskal-Wallis e Student-Newman-Keuls (p<0,05). Houve maior número de ciclos reprodutivos no CT que nos demais grupos no período de 29 dias (p<0,05), nenhuma diferença foi encontrada entre os grupos na dosagem hormonal ou na espessura de endométrio. Portanto, conclui-se que o GH, o exercício resistido e os dois combinados interferem na ciclicidade reprodutiva das fêmeas, reduzindo o número de ciclos das ratas, sem alterar a concentração de estradiol e progesterona ou a espessura do endométrio.

The purpose of the study was to determine if subjects would improve in cardiovascular efficiency following a six-week program of trampolining and/or tumbling. Literature concerning cardiovascular efficiency, training, trampoline, testing instruments, test selection and maximal oxygen intake were thoroughly reviewed. The Astrand test of maximal oxygen intake and the Cooper twelve-minute run test of aerobic capacity were found to best fit the needs of the present study.

Introducción: Las caídas son uno de los principales problemas a los que se enfrenta hoy la población de adultos mayores. Objetivo: Determinar la efectividad de un programa de ejercicios físicos de 12 semanas de duración en comparación al mismo de 2 semanas, para reducir el riesgo de caídas en este grupo humano. Métodos: Estudio experimental paralelo y aleatorizado con dos grupos de intervención realizado a adultos mayores (AM) pertenecientes al Centro Integral del Adulto Mayor. Los participantes aleatorizados fueron 13 AM (Grupo 1 = 5; grupo 2 = 8). Se utilizó la prueba Timed Up and Go (TUG) para determinar el riesgo de caídas, y se les aplicó un cuestionario para obtener datos personales. Se ejecutó un mismo programa de ejercicios para ambos grupos, y solo se diferenció en el número de sesiones (Grupo 1 = 4 sesiones; Grupo 2 = 24 sesiones). Resultados: La mayor cantidad de participantes fueron mujeres, y presentaron un nivel de actividad física bajo en ambos grupos. El TUG reveló, al inicio, que el 87,5% del Grupo 2 presentó un riesgo normal/leve de caídas; y, al final del programa, que el total se encontraba ahí. El número de caídas desde la evaluación inicial a la final se redujo alrededor del 20%. Por último, la diferencia total del TUG inicial y final es una reducción de 0,46 segundos. En ninguna de las variables se encontró asociación significativa (p > 0,01) para ambos grupos. Conclusión: No se encontró asociación significativa entre realizar un programa de ejercicios físicos de 12 semanas en comparación al mismo programa con 2 semanas de duración para reducir el riesgo de caídas. / Introduction: Nowadays, falls have become one of the main problems faced by the elderly population. Objective: To determine the effectiveness of a 12-week exercise program compared to the same 2-week program to reduce the risk of falls in this human group. Methods: Randomized parallel experimental study with two intervention groups performed to elderly people (EP) belonging to Centro Integral del Adulto Mayor. The randomized participants were 13 EP (Group 1 = 5; Group 2 = 8). The test Timed Up and Go (TUG) was used to determine the risk of falls, and it was applied a questionnaire to them in order to obtain personal data. Same exercise program was implemented for both groups and only differed in the number of sessions (Group 1 = 4 sessions; Group 2 = 24 sessions). Results: Most participants were women, who had a low level of physical activity in both groups. The TUG revealed in the beginning that the 87,5% of Group 2 had a normal/low risk of falls and at the end of the program the total was found there. The number of falls from the initial to the final evaluation was reduced by about 20%. Finally, the total difference between the initial and final TUG is a reduction of 0,46 seconds. In any of the variables no significant association was found (p > 0.01) for both groups. Conclusion: No significant association was found between performing a 12-week physical exercise program compared to the same 2-week program to reduce the risk of falls. / Tesis

This study has aimed to evaluate how osteoporosis affects the quality of life in postmenopausal women and to assess the influence of physical exercise on markers for quality of life in osteoporosis patients. The EQ-5D questionnaire was applied for evaluation of the markers: Mobility, Self-care, Usual Activities, Pain/Discomfort and Anxiety/Depression. In collaboration with the University of Bologna, a 6-month exercise trial of women aged 60-75 with osteoporotic vertebral fractures was analyzed. These osteoporosis patients were divided into two groups; an exercise group and a control group. Markers linked to quality of life were compared for the women with osteoporosis with those of an average female Italian population of similar age. Markers for quality of life, specifically: Mobility, Usual Activities, Pain/Discomfort and Anxiety/Depression were significantly lower in the Italian osteoporosis patients than in the average population. Exercise slightly improved Mobility and Usual Activities for the osteoporosis patients, but the results did not reach statistical significance.

El presente proyecto de una aplicación que busca fomentar la comunidad, interacción virtual y colaboración hacia personas que desean implementar o mantener un estilo de vida saludable muestra la viabilidad de su ejecución, con base en los experimentos realizados al público objetivo (entrevistas): personas que realizan deporte o siguen una buena alimentación y los profesionales de la salud (nutricionistas y preparadores físicos), los cuales son considerados actores importantes en el éxito de esta iniciativa. Por un lado, se halló que en el primer grupo suelen presentar desmotivación al inicio de sus nuevos regímenes. Por otro lado, los del segundo grupo, consideraron que el aplicativo resultaría eficiente, según el propósito que sigue. Para llevar a cabo este proyecto, se requiere la implementación, en primer lugar, de una app nativa, cuyo almacenamiento más próximo sean PlayStore y AppStore, ya que, según la investigación, son las tiendas virtuales más usadas por los usuarios a través de sus teléfonos celulares. Esto implica el costo de un desarrollo por encargo de aproximadamente S/ 3000.00, así como el pago de los servidores en donde se hospedará la arquitectura y almacenamiento de la codificación, cuyo costo inicial es de S/ 0.195. Por otra parte, se requiere implementar un plan de marketing y fidelización a través de estrategias como penetración de mercado -al cual se le destinará S/ 500- , creación de comunidad y, finalmente, medir los resultados a través de NPS, indicador que refleja el grado de lealtad y fidelización por parte de los consumidores. / The present project of an application that seeks to promote community, virtual interaction and collaboration with people who want to implement or maintain a healthy lifestyle shows the feasibility of its execution, based on the experiments carried out on the target audience (interviews): people who they practice sports or follow a good diet and health professionals (nutritionists and physical trainers), who are considered important actors in the success of this initiative. On the one hand, it was found that in the first group they tend to show demotivation at the beginning of their new regimens. On the other hand, those in the second group considered that the application would be efficient, according to the purpose that follows. To carry out this project, the implementation is required, first of all, of a native app, whose closest storage is Play Store and AppStore, since, according to the research, they are the virtual stores most used by users through their cellphones. This implies the cost of a custom development of approximately S / 3000.00, as well as the payment of the servers where the architecture and storage of the coding will be hosted, whose initial cost is S / 0.195. On the other hand, it is necessary to implement a marketing and loyalty plan through strategies such as market penetration -which will be allocated S / 500-, community creation and, finally, measuring the results through NPS, an indicator that reflects the degree of loyalty and loyalty on the part of consumers. / Trabajo de investigación

Ce travail de thèse présente une approche clinique et thérapeutique visant à fournir de nouvelles techniques de soins pour les patients atteints de troubles neurocognitifs et notamment de maladie d’Alzheimer. Les serious exergames sont des jeux vidéo sérieux intégrant une activité physique. Ils peuvent constituer des outils de production d’environnement enrichi pour les utilisateurs, en associant notamment exercice physique et entraînement cognitif. L’objectif de cette thèse est d’explorer en quoi les serious exergames peuvent contribuer à la prise en charge non médicamenteuse des troubles neurocognitifs. Dans ce travail, nous avons réalisé deux types de contribution. Les premières contributions sont générales, l’une présente notre approche clinique intégrative combinant exercice physique et entraînement cognitif via l’utilisation de serious exergames, et l’autre présente des recommandations concernant l’usage des serious games. Les secondes contributions sont de nature expérimentale. La première expérimentation vise à vérifier une des bases théoriques de notre approche clinique. Les deux expérimentations suivantes constituent une évaluation de la mise en œuvre de notre approche. / This thesis presents a clinical and therapeutic approach aiming to create new care for patients with neurocognitive disorder. Serious exergames are serious video games integrating physical activity. Serious exergames could be tools to product enriched environment associating physical exercise and cognitive training. The aim of this thesis is to investigate whether serious exergames can contribute to the non-pharmacological management of neurocognitive disorders. In this thesis we have made two types of contributions. The first type are general contributions. One presents our integrative clinical approach associating physical exercise and cognitive training using serious exergames. The other one presents recommendations concerning the use of serious exergames. The second type of contributions are experimental. The first one aims to confirm a theoretical base of our clinical approach. The two other experiments assess the implementation of our approached in a population of patients with neurocognitive disorder.

Eine angemessene, regelmäßige sportliche Aktivität wirkt protektiv auf die Erhaltung und Wiederherstellung körperlicher und geistiger Gesundheit. Die Herzinsuffizienz ist nicht zuletzt durch ihre hohe Prävalenz ein internistisches Krankheitsbild von enormer Relevanz im klinischen Alltag. Im Rahmen einer bestehenden Herzinsuffizienz kann es zur pathophysiologischen Ausprägung einer gestörten Endothelfunktion kommen, welche sich in einer verringerten endothelialen Dilatationsfähigkeit ausdrücken kann. Das Ziel dieser Dissertation bestand in der Untersuchung der Auswirkungen eines körperlichen Trainings auf die Funktionsleistung der Endothelzellen von herzinsuffizienten Mäusen. Hierzu wurde in einem operativen Eingriff durch die Ligatur des Ramus interventricularis anterior bei jungen Mäusen ein herzinsuffizientes Tiermodell geschaffen und der sekundärpräventive Effekt eines anschließenden zehnwöchigen Laufbandtrainings eruiert. Als Funktionsmaß der Endothelzellen diente dabei ihre endothelabhängige Dilatationsfähigkeit, welche im Organbad erhoben wurde. Weiterhin lag der Fokus auf der Untersuchung des Einflusses der im Endothel exprimierten microRNA-21 und microRNA-126 im trainierten und untrainierten herzinsuffizienten Aortenendothel. Ihre Expression wurde in den verschiedenen Versuchsgruppen quantitativ mittels Real-Time PCR erfasst. In einem weiteren Ansatz bestand das Ziel, den Einfluss einer Angiotensin II- beziehungsweise Zytokinstimulation - als Modell eines mit der Herzinsuffizienz vergesellschafteten Inflammationsgeschehens - auf diese beiden endothelexprimierten microRNAs zu erforschen.

This diploma thesis takes interest in the issue of physical activities of children with cystic fibrosis, in possible impacts of such activities on clinical condition, in options of prescription of physical activities based on the actual clinical state of a person with cystic fibrosis, and in options of objectification of changes induced by an exercise programme. The theoretic part of this thesis summarizes the current findings about cystic fibrosis, therapy and physical activities in the context of prognosis of patients with cystic fibrosis. In experimental part, we performed examinations on few participants, who were willing to perform a home-based exercise programme. Also, we made a short exploratory questionnaire focused on the attitude of children with cystic fibrosis towards physical exercises. Methodology: We observed the evolution of maximal oxygen uptake VO2max, forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC) and of the scores of 1- minute sit-to-stand test (1-MSTST). All the measurements were performed before and after 12- weeks long exercise intervention. The inclusion criteria were diagnosis of cystic fibrosis, age over 10 years, FEV1 over 60 % predicted and no present signs of an acute exacerbation. Participants were assessed by spirometry examination,...

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Alsvold-Törndahl, R & Rödiger, U. Effekt av fysisk träning som preventiv åtgärd mot kognitiv svikt hos äldre. En litteraturstudie. Examensarbete i omvårdnad 15 högskolepoäng. Malmö högskola: Fakulteten för Hälsa och samhälle, institutionen för vårdvetenskap, 2016.Bakgrund: Andelen äldre växer och därmed andelen som lider av kognitiv svikt. Metoder för att upprätthålla och främja hälsa blir allt viktigare.Syfte: Belysa effekten av fysisk träning som preventiv åtgärd mot kognitiv svikt hos äldre över 55 år.Metod: Avsikten var att samla studier, med kvantitativ ansats, vilka visade samband mellan fysisk träning som en förebyggande metod mot kognitiv svikt. Artiklar, med kvantitativ ansats, söktes med hjälp av databaserna PubMed och CINAHL.Resultat: Sambandet, där fysisk träning verkar positivt, som prevention mot kognitiv svikt, kan ses genom de samlade studiernas olika mätmetoder. Komplexitet, emellertid, visar på möjligheten där påverkan av andra individuella faktorer inte kan uteslutas.Konklusion: Kognitiv svikt kan påverkas genom fysisk träning. / Alsvold-Törndahl, R & Rödiger, U. Effect of physical exercise as a preventive intervention against cognitive impairment of elderly. A literature review. Degree Project in nursing 15 credit points. Malmö University: Faculty of Health and Society, Department of Care Science, 2016.Background: The proportion of elderly is growing and thus the proportion that are affected by cognitive impairment. Methods for maintaining and promoting health are becoming increasingly important.Aim: Illustrate the effect of physical exercise as a preventive action against cognitive impairment by elderly 55 years and older.Method: The intention was to gather studies, with quantitative approach, which showed connection between physical exercises as a preventive method against cognitive impairment. Articles, with quantitative approach, were searched using the databases of PubMed and CINAHL.Results: The context, in which physical exercise appears positive, as prevention against cognitive impairment, can be seen through the gathered studies' different measurement methods. Complexity, however, is showing the possibility to the influence by other individual factors that cannot be ruled out.Conclusion: Cognitive impairment can be influenced by physical exercise.