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Contribuição da ultra-sonografia no diagnóstico da forma hepato-esplênica da esquistossomose mansônica / Ultrasonography in the diagnosis of the hepatosplenic form of schistosomiasis mansoniGiovanni Guido Cerri 13 March 1984 (has links)
O trabalho discute a utilidade da ultra-sonografia, no diagnóstico da forma hepato-esplênica da esquistossomose mansônica. O autor estudou, pela ultra-sonografia, 103 pacientes com esquistossomose hepato-esplênica comprovada e observou os sinais encontrados no fígado, vias biliares, baço e circulação portal. Foi determinada a freqüência dos diferentes sinais presentes no grupo de pacientes esquistossomóticos e feita correlação com as alterações anátomo-patológicas da doença. Os valores dos calibres das veias esplênica, porta e mesentêrica superior dos nossos pacientes esquistossomóticos foram comparados aos encontrados em 50 pacientes sem anormalidades hepáticas (grupo-controle). As alterações encontradas no fígado incluíram espessamento da parede da veia porta e seus ramos, nódulos parenquimatosos, atrofia do lobo direito e hipertrofia do lobo esquerdo. O espessamento da parede dos vasos portais correlaciona-se a fibrose peri-portal encontrada no exame anátomo-patológico e foi sinal muito freqüente. A atrofia do lobo direito e a hipertrofia do lobo esquerdo devem estar relacionadas ao hiperfluxo pela veia esplênica. Os nódulos parenquimatosos representam os granulomas que, pelas suas pequenas dimensões, são raramente visualizados pela ultra-sonografia. A vesícula biliar apresentou espessamento de sua parede em número significativo dos pacientes estudados. O baço encontrou-se aumentado de volume em todos os pacientes, atingindo geralmente grandes proporções. Em pequeno número de casos observou-se padrão multinodular que foi atribuído aos nódulos sideróticos encontrados ocasionalmente na esquistossomose. A média dos calibres da veia porta, veia esplênica e veia mesentérica superior, nos pacientes esquistossomóticos, foi estatisticamente superior à dos pacientes do grupo-controle. O aumento do calibre foi mais acentuado para a veia esplênica do que para a veia mesentérica superior. Os vasos colaterais estudados foram a veia umbilical, a veia gástrica esquerda e os vasos gástricos curtos, não apresentando características particulares para esta doença. A trombose da veia porta foi encontrada em raros casos. Os principais sinais sonográficos da esquistossomose hepato-esplênica incluem fibrose peri-portal, hipertrofia do lobo esquerdo, espessamento da parede da vesícula biliar, nódulos hepáticos, padrão multinodular do baço e aumento do calibre dos vasos portais. Sinais sonográficos freqüentes porém inespecíficos, incluem esplenomegalia e vasos colaterais. O autor considera o exame ultra-sonográfico método importante no diagnóstico não invasivo da esquistossomose hepato-esplênica / The paper discusses the usefulness of ultrasonography in the diagnosis of the hepatosplenic form of schistosomiasis mansoni. The author studied, sonographically, 103 patients with comproved hepatosplenic schistosomiasis and observed the signs found in the liver, biliary tract, spleen, and portal system. The frequency of the different signs present in the group of schistosomotic patients had been determined and the correlation with the anatomopathological alterations of the disease was done. The values of the diameter of the splenic, portal and superior mesenteric veins in the schistosomotic patients was compared with the ones found in 50 patients without hepatic abnormalities. The alterations found in the liver includes the thickening on the wall of the portal vein and its branches; atrophy of the right lobe and hypertrophy on the left lobe and hepatic nodules. The thickening of the wall of the portal vessels is correlated to the periportal fibrosis found in the anatomopathologic examination and is a very frequent sign. The atrophy of the right lobe and the hypertrophy of the left lobe is most probably related to the higher vascular flow through the splenic vein. The hepatic nodules represent granulomas that, due to their small dimentions, are seldom visualized by ultrasonography. The thickening of the gallbladder wall, was found in a significant number of the studied patients. The spleen presented an enlarged volume in all patients, reaching generally big proportions. In a small number of cases a multinodular pattern was observed and it has been atributed to the siderhotic nodules occasionally found in schistosomiasis. The average of the diameters of the portal, splenic and superior mesenteric veins of the patients with schistosomiasis was statistically higher than the ones found in the control group. The enlargement of the diameter was more accentuated in the splenic vein rather than in the superior mesenteric vein. The collateral vessels studied were the umbilical vein, the left gastric vein and the short gastric vessels, not presenting particular characteristics for this disease. Thrombosis of the portal vein was rarely found. The main sonographic signs of the hepatosplenic schistosomiasis include periportal fibrosis, hypertrophy of the left lobe, thickening of the wall of the gallbladder, granulomas, multinodular pattern of the spleen and enlargement of the diameter of the portal vessels. Frequent sonographical signs, but nonspecific, include splenomegaly and collateral vessels. The author considers the ultrasonographic examination an important method in the non invasive diagnosis of this disease
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Constru??o coletiva do Portal Educa??o do Campo / Collective construction of Field Education PortalSOARES, Andr? Jos? Diniz 23 February 2017 (has links)
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Previous issue date: 2017-02-23 / The observations made, everyday at Boa Esperan?as CEIER, configured the teaching of agrarian sciences as a challenge for elementary school. The problems encountered by the lack of financial resources in the animal, vegetable and domestic economy sectors. The lack of appropriate didactic material for the students' age and cultural,as well as the non-eplacement of necessary equipments for the field education modality, was a limiting factor for the development of the theoretical and practical classes of the disciplines.All the difficulties encountered day in day outin school justified a more in-depth and in-depth study to develop a less costly alternative, supplying or at least attenuating the adversities encountered in the field.Therefore, the objective of this research to build an educational portal of didactic resources that would attend the specificities of the field education modality, serving as a pedagogical resource in the disciplines that make up the diverse part of Boa Esperan?a?s CEIER. Thereunto, the construction of the Education Portal of the Field was divided in stages known as ADDIE model, widely used in classical instructional design.The analysis phase of the target audience was a brief history of the creation of the municipality of Boa Esperan?a and the construction of the Integrated State Center for Rural Education and its methodology directed to the field education modality.The result of this step was the starting point for the drawing phase, which required careful and detailed planning, attending the requirements of teachers of the diversified part.In the development phase there was the construction of the pages to allocate tools and store multimedia content, being performed by a website builder software that also indicated the frequency, totaling 19064 visitors over a period of twelve months. In the implementation, the portal of the Education of the Field and its proposal of collective construction in the Facebook social network was announced, which indicated 12 audio contents, 86 videos and 108 text files. The evaluation of the portal was made Boa Espearan?a?s CEIER teachers using a usability questionnaire based on the pedagogical characteristics of educational software on the internet. The educational environment category had the recommended usability because it allowed 82% of identification with the target public. In the didactics aspects category, the usability was highly recommended, contributing 91.50% in range the educational goal. Similarly, the pertinence category in relation to the curricular program obtained 83% in relation to the adequacy to the educational context and Boa Esperan?a?s CEIERsubjects , and usability is recommended. The overall average of the attributes of the pedagogical characteristics was 85.50%, and being recommended the usability of the portal. In front of all the above, it can be affirmed that the Field Education Portal has the capacity to satisfy the specific needs of the education modality of the field and it brings together sufficient attributes to ameliorate or even supply the lack of practical classes in the disciplines that make up the diversified part. However, with the limitation of Internet access in the school, the adequacy of the Education of the Field Portal to the educational context of Boa Esperan?a?s CEIER was harmed. / As observa??es feitas, cotidianamente no CEIER de Boa Esperan?a, configuravam o ensino de ci?ncias agr?rias como um desafio para o ensino fundamental. Os problemas encontrados pela falta de recursos financeiros nos setores de produ??o animal, vegetal e economia dom?stica. A car?ncia de material did?tico apropriado para faixa et?ria e cultural dos estudantes, bem como a n?o reposi??o de equipamentos necess?rios a modalidade educa??o do campo, era um fator limitante para o desenvolvimento das aulas te?ricas e pr?ticas das disciplinas. Todas as dificuldades encontradas cotidianamente na escola justificavam um estudo mais embasado e aprofundado para desenvolver uma alternativa menos onerosa, suprindo ou pelo menos atenuando as adversidades encontradas no campo. Sendo assim, o objetivo dessa pesquisa foi construir um portal educacional de recursos did?ticos que atendesse as especificidades da modalidade educa??o do campo, servindo como recurso pedag?gico nas disciplinas que comp?e a parte diversificada do CEIER de Boa Esperan?a. Para isso, a constru??o do portal Educa??o do Campo foi dividida em fases conhecida como modelo ADDIE, amplamente utilizado no design instrucional cl?ssico. A fase de an?lise do p?blico alvo constituiu um breve hist?rico da cria??o do munic?pio de Boa Esperan?a e a da constru??o do Centro Estadual Integrado de Educa??o Rural e sua metodologia direcionada a modalidade educa??o do campo. O resultado desta etapa foi o ponto de partida para a fase de desenho, que exigiu um planejamento minucioso e detalhado atendendo as exig?ncias de professores da parte diversificada. Na fase de desenvolvimento ocorreu a constru??o das p?ginas para alocar ferramentas e armazenar conte?do multim?dia, sendo realizada por um software construtor de sites que tamb?m indicou a freq??ncia, totalizando 19064 visitantes em um per?odo de doze meses. Na implementa??o, realizou-se a divulga??o do portal Educa??o do Campo e a sua proposta de constru??o coletiva na rede social facebook, que indicou 12 conte?dos de ?udio, 86 de v?deos e 108 arquivos de texto. A avalia??o do portal foi realizada pelos professores do CEIER de Boa Esperan?a utilizando um question?rio de usabilidade fundamentado nas caracter?sticas pedag?gicas de softwares educacionais na internet. A categoria ambiente educacional teve a usabilidade recomendada, pois permitiu 82% de identifica??o com o p?blico alvo. Na categoria aspectos did?ticos, a usabilidade foi altamente recomendada, contribuindo em 91,50% no alcance do objetivo educacional. Da mesma forma, a categoria pertin?ncia em rela??o ao programa curricular obteve 83% em rela??o ? adequa??o ao contexto educacional e as disciplinas do CEIER de Boa Esperan?a, sendo recomendada a usabilidade. A m?dia geral dos atributos das caracter?sticas pedag?gicas foi de 85,50% sendo recomendada a usabilidade do portal. Diante de todo o exposto, pode-se afirmar que o portal Educa??o do Campo possui a capacidade de satisfazer as necessidades espec?ficas da modalidade educa??o do campo e re?ne atributos suficientes para amenizar ou at? mesmo suprir a falta de aulas pr?ticas nas disciplinas que comp?e a parte diversificada. Por?m, com a limita??o de acesso a internet na escola, a adequa??o do portal Educa??o do Campo ao contexto educacional do CEIER de Boa Esperan?a foi prejudicado.
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...folkmusikportalen.se : En mötespunkt på Internet? / ...folkmusikportalen.se : A place to meet on the Internet?Sjögren, Pia-Karin January 2008 (has links)
<p>Jag har undersökt vad människor i Folkmusiksverige vill läsa om på en kommande internetportal, folkmusikportalen.se. Detta har jag gjort genom en enkät, som låg på Internet och var öppen i två veckor. Jag fick in 81 svar. Frågorna jag ställde handlade om respondenternas bakgrund, hur de ställer sig till reklam, vad de vill läsa/diskutera om och vilka konferenser de eventuellt har besökt och vilka ämnen som isf togs upp där.Jag har kommit fram till att intresset för en kommande portal är stort. Jag har fått mycket förslag på vilka ämnen och funktioner som skulle kunna finnas med på portalen. Det rör sig om CD-recensioner, reportage, händelsekalender, länkar och ett forum där det finns ett oändligt antal ämnen som bara väntar på att få diskuteras!</p> / <p>I examined what people, who take part in Swedish folk music, want to read and discuss on the upcoming internet forum, folkmusikportalen.se. I used a survey to obtain my answers. The inquiry was posted online, and was available for users during a two-week period. 81 people answered my survey. The questions dealt with the background of the recipients, if they want to advertise, what they want to read/discuss, and which conferences they attended and which subjects were discussed there. I discovered that the forum was received with great interest. I have received numerous suggestions with regard to what subjects and functions would be fun to have on this internet portal. Many would like to see CD-reviews, reports, a calendar, links and a forum where there is an infinite amount of subjects waiting to be discussed.</p>
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Marktüberblick : Anwendungen und Systeme für das Wissensmanagement / Applications and systems for knowledge management : a market surveyGronau, Norbert January 2005 (has links)
Diese Marktstudie vermittelt einen Überblick über Software, die zur Unterstützung von Wissensmanagement eingesetzt werden kann und berücksichtigt dabei die Spannweite von spezialisierten Suchmaschinen bis zu umfassenden integrierten Wissensmanagementsystemen. Die untersuchte Software bietet sowohl
Unterstützung bei Community-orientierten Wissensmanagementansätzen als auch bei Information Retrieval. Die Einsatzmöglichkeiten sind genauso unterschiedlich wie die heterogenen Anforderungen von Unternehmen und Organisationen, die diese an Wissensmanagement stellen. Eine direkte Vergleichbarkeit aller untersuchten
Softwareprodukte ist daher nicht sinnvoll. / Applications and systems for knowledge management : a market survey:
<br><br>
This market survey gives an overview on software for the support of knowledge
management. The survey overlooks the span from specialized search engines to integrated knowledge management systems with a broad range of functions. The investigated software supports community-oriented approaches as well as information retrieval. Usage possibilities are as different as the heterogenous
requirements of enterprises and organizations for knowledge management. Therefore a direct comparison between the investigated tools is not useful.<br>
-----<br>
© GITO mbH Berlin
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...folkmusikportalen.se : En mötespunkt på Internet? / ...folkmusikportalen.se : A place to meet on the Internet?Sjögren, Pia-Karin January 2008 (has links)
Jag har undersökt vad människor i Folkmusiksverige vill läsa om på en kommande internetportal, folkmusikportalen.se. Detta har jag gjort genom en enkät, som låg på Internet och var öppen i två veckor. Jag fick in 81 svar. Frågorna jag ställde handlade om respondenternas bakgrund, hur de ställer sig till reklam, vad de vill läsa/diskutera om och vilka konferenser de eventuellt har besökt och vilka ämnen som isf togs upp där.Jag har kommit fram till att intresset för en kommande portal är stort. Jag har fått mycket förslag på vilka ämnen och funktioner som skulle kunna finnas med på portalen. Det rör sig om CD-recensioner, reportage, händelsekalender, länkar och ett forum där det finns ett oändligt antal ämnen som bara väntar på att få diskuteras! / I examined what people, who take part in Swedish folk music, want to read and discuss on the upcoming internet forum, folkmusikportalen.se. I used a survey to obtain my answers. The inquiry was posted online, and was available for users during a two-week period. 81 people answered my survey. The questions dealt with the background of the recipients, if they want to advertise, what they want to read/discuss, and which conferences they attended and which subjects were discussed there. I discovered that the forum was received with great interest. I have received numerous suggestions with regard to what subjects and functions would be fun to have on this internet portal. Many would like to see CD-reviews, reports, a calendar, links and a forum where there is an infinite amount of subjects waiting to be discussed.
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Determination and Mitigation of Precipitation Effects on Portal Monitor Gamma Background LevelsRevis, Stephen 2012 May 1900 (has links)
The purpose of this project is to establish a correlation between precipitation and background gamma radiation levels at radiation portal monitors (RPM) deployed
at various ports worldwide, and to devise a mechanism by which the effects of these precipitation-induced background fluctuations could be mitigated. The task of detecting special nuclear materials (SNM) by passive gamma spectroscopy is very difficult due to the low signal-to-noise ratio observed in an uncontrolled environment. Due to their low activities and the low energies of their characteristic gamma rays, the signals from many types of SNM can easily be obscured by background radiation. While this can be somewhat mitigated by taking regular background radiation measurements, even this cannot resolve the issue if background levels change suddenly and dramatically. Furthermore, any increase in background count rate will increase the statistical uncertainty of the count rate measurement, and thus decrease the minimum quantity of SNM that can be reliably detected. Existing research suggests that the advent of precipitation is the culprit behind many such large and sudden increases in background radiation. The correlation between precipitation and background levels was explored by in-situ testing on a full-scale portal monitor at Oak Ridge National Laboratory, and by comparing previously recorded background radiation and weather data from portal monitors located at ports worldwide. The first was utilized to determine the frequency and magnitude at which precipitation introduces background activity, and the second was used to quantify the effects of various quantities and types of precipitation in various parts of the world. Once this analysis was complete, various methods of mitigating these changes in background radiation were developed based on the collected data.
Precipitation was found to be the most common culprit for rapid increases in background count rate, and was attributable to 85.6% of all such events. Based on extensive simulation via the Origen-ARP and MCNP software, a response function for the portal monitor was developed, and an algorithm designed to predict the contribution of the precipitation to the background count rate was developed. This algorithm was able to attenuate the contribution of precipitation to the background count rate by an average of 45% with very minimal over-correction. Such an algorithm could be utilized to adjust the alarm levels of the RPM to better allow it to compensate for the rise and fall in background count rate due to precipitation.
Additionally, the relative contribution of precipitation which landed at various distances from the portal monitor to the increase in background count rate was measured via simulation. This simulation demonstrated that 37.2% of all background counts were due to the radon daughters which landed within a 2.76 m radius from the center of the portal monitor. This radius encompasses the area between the two portals. Based on this, several designs for shielding were simulated, the most successful of which was a concrete structure that was able to attenuate 71.3% of the background radiation caused by a given precipitation event at a materials cost of approximately $6,000 per RPM. This method is recommended as the primary means of mitigating this issue.
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Small-for-size graft in liver transplantationKiuchi, Tetsuya, Oike, Fumitaka, Yamamoto, Hidekazu 11 1900 (has links)
No description available.
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Splenic neurohormonal modulation of renal and mesenteric hemodynamics in portal hypertensionHamza, Shereen M. January 2009 (has links)
Thesis (Ph.D.)--University of Alberta, 2009. / A thesis submitted to the Faculty of Graduate Studies and Research in partial fulfillment of the requirements for the degree of Doctor of Philosophy, Department of Physiology. Title from pdf file main screen (viewed on August 16, 2009). Includes bibliographical references.
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Ação da N-acetilcisteína (NAC) na gastropatia da hipertensão portalLicks, Francielli January 2013 (has links)
A Hipertensão Portal (HP) é uma síndrome clínica associada ao desenvolvimento de circulação hiperdinâmica e varizes gastroesofágicas. O objetivo deste estudo foi avaliar a ação antioxidante da N-Acetilcisteína (NAC) em ratos com hipertensão portal. MATERIAIS E MÉTODOS: A HP foi induzida por meio do modelo experimental de ligadura parcial da veia porta (LPVP) e os animais divididos em quatro grupos experimentais (n=6): Sham-operated (SO), SO + NAC, LPVP e LPVP + NAC. A NAC (10 mg/kg ip.) foi administrada diariamente durante 7 dias, iniciados no 8º dia após a cirurgia. Foi mensurada a pressão portal na veia mesentérica, e o dano hepático foi avaliado através das enzimas AST, ALT e FA. Para avaliação do dano oxidativo no estômago, foi feita a avaliação da lipoperoxidação através da técnica das substâncias que reagem ao ácido tiobarbitúrico (TBARS) e avaliadas as atividades das enzimas antioxidantes SOD e GPx. Também foram avaliados os níveis de metabólitos do óxido nítrico (nitritos e nitratos), e, para avaliação dos aspectos histológicos, mensuramos os calibres dos vasos na submucosa gástrica, bem como analisamos lâminas coradas com hematoxilina-eosina. RESULTADOS: Os animais do grupo LPVP apresentaram um aumento significativo nos valores de pressão portal, TBARS e metabólitos do óxido nítrico quando comparados ao grupo SO. Esses valores foram acompanhados por uma diminuição das enzimas antioxidantes SOD e GPx. Na análise histológica, notaram-se vasos dilatados e presença de edema na mucosa gástrica dos animais do grupo LPVP. O tratamento com a NAC foi capaz de diminuir os valores da pressão portal, TBARS e metabólitos do óxido nítrico quando comparados ao grupo LPVP. Além disso, foi observado um aumento na atividade das enzimas antioxidantes superóxido dismutase (SOD) e glutationa peroxidase (GPx). Na avaliação da histologia do estômago, a NAC atenuou o edema e vasodilatação nos animais do grupo LPVP +NAC. Não houve diferença estatística significativa entre os valores das enzimas hepáticas. CONCLUSÕES: Sugerimos que a administração da N-acetilcisteína em ratos com hipertensão portal é eficaz na redução ao dano gástrico infligido pelo modelo experimental de ligadura parcial da veia porta. / Portal Hypertension (PH) is a clinical syndrome associated with the development of a hyperdynamic circulation and gastroesophageal varices. The aim of this study was to evaluate the antioxidant effect of N-Acetylcysteine (NAC) on portal hypertensive rats. MATERIAL/METHODS: PH was induced by partial portal vein ligature (PPVL), and the animals were divided into four experimental groups (n = 6): Sham-operated (SO), SO + NAC, PPVL and PPVL + NAC. NAC (10 mg / kg ip.) was administered for 7 days daily, beginning on the 8th day after surgery. Portal pressure was measured in mesenteric vein and liver damage was assessed by the enzymes AST, ALT and FA. To assess oxidative damage in the stomach, the technique of substances that react to thiobarbituric acid (TBARS) was performed and the activities of antioxidant enzymes dismutase (SOD) and glutathione peroxidase (GPx) was evaluated. The nitric oxide metabolites levels (nitrites and nitrates) were also evaluated and histological evaluation was made by measuring the vessels sizes in the gastric submucosa and blades stained with hematoxylin-eosin were analyzed. RESULTS: PPVL animals showed a significant increase in portal pressure, TBARS and nitric oxide metabolites values when compared to the SO group. These values were accompanied by a decrease of antioxidant enzymes SOD and GPx. In histological analysis, dilated vessels and edema in gastric mucosa of PPVL group were noted. Treatment with NAC was able to decrease portal pressure, TBARS and nitric oxide metabolites values when compared to PPVL. Furthermore, an increase in antioxidant enzymes SOD and GPx activity was observed. In the assessment of stomach histology, NAC attenuated the vasodilation and edema in PPVL + NAC group. There was no statistically significant difference between the values of liver enzymes. CONCLUSIONS: We suggest that N-acetylcysteine administration in rats with portal hypertension is effective in reducing gastric damage inflicted by the experimental model of partial portal vein ligation.
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Elementos de dimensão social no alinhamento estratégico : uma análise sob a ótica da estratégia enquanto práticaAbib, Gustavo January 2011 (has links)
Motivado pela importância que o Alinhamento Estratégico entre negócio e T.I. representa para as organizações e pelo fato de que apesar de uma extensa literatura que discute os modelos de alinhamento estratégico, sua obtenção ainda é considerada um problema pelas organizações. Os modelos falham, porém, em compreender como o alinhamento é estabelecido e como a dimensão social – o conjunto formado pela estrutura organizacional e seus atores, os relacionamentos, as práticas e as práxis, a tecnologia e o contexto – está presente nesse processo. Sendo assim, este estudo baseado na corrente teórica denominada de estratégia enquanto prática objetivou analisar como a dimensão social está presente no processo de alinhamento estratégico da informação. Foi realizado um estudo de caso único em profundidade em uma empresa líder no seu segmento estudando o processo de implantação de um portal corporativo e como estratégia de coleta de dados para este estudo de caso utilizou-se a observação participante. O estudo demonstrou que o movimento em direção ao AE necessariamente é controlado pelos atores internos da organização e muitas vezes não pelo nível hierárquico estratégico, nem tático, mas pelo nível operacional. Mesmo com a presença de atores externos, qualificados e comprometidos, as práxis e o entendimento dos atores internos se sobrepõem à experiência dos atores externos. A análise integrada dos resultados permite compreender como os gestores constroem seus links entre suas micro-atividades e as macro-estruturas de suas organizações e os impactos do contexto. Os resultados permitiram ainda fornecer conceitos teóricos úteis para compreender como que os gestores “estrategizam” durante o processo de alinhamento. Dentre os conceitos analisados ressalta-se a importância de lidar com os aspectos sociais imbricados no fazer estratégia. Apesar de todo o movimento acadêmico chamar atenção para os aspectos sociais, a dualidade da estrutura (JONES; Karsten, 2008), a análise das redes sociais (CIBORRA, 2002; LATOUR, 2001), percebe-se na prática o pouco interesse empregado pelos gestores na busca do entendimento desses elementos. O aprisionamento aos aspectos técnicos fica evidente durante todo o processo de implantação do portal, reduzindo a efetividade na obtenção do AE. As abordagens utilizadas e a discussão e análise dos resultados sugerem direções para um possível incremento no entendimento do alinhamento, trazendo para reflexão a importância dos atores, suas práticas, a compreensão do lócus do alinhamento e seus relacionamentos. / Motivated by the importance that the strategic alignment between business and technology represents for organizations and despite an extensive literature on the strategic alignment models, its obtainment is still considered a problem by the organizations. The models fail, however, in understanding how the alignment is established and how the social dimension - the group formed by the organizational structure and its actors, relationships, practices and praxis, technology and context - act in this process. Thus, this study, based on the strategy as practice, aimed to analyze how the social dimension is present in the process of strategic alignment of information. A single case study in a leading company in its industry was conduct in depth by analyzing the process of implementation of a corporate portal and the strategy of data collection for this case study was through a participant observation. The study showed that the movement toward the AE is necessarily controlled by internal actors within the organization and often not at a hierarchical strategic level, neither at the tactical one, but at the operational level. Even with the presence of skilled and committed external actors, the practice and understanding of the internal actors overlap the experience of external actors. The integrated analysis of the results provides insight into how managers build their links between their micro-activities and macro-structures of their organizations and the impact of context. The results also helped to provide some useful theoretical concepts for understanding how the managers are "strategizing" during the alignment process. Among the concepts discussed, the importance of dealing with social issues intertwined in strategizing is emphasized. Despite the academic movement that calls attention to social aspects, the duality of structure (Jones, Karsten, 2008) and the social network analysis (Ciborra, 2002; Latour, 2001), we found little interest in the practice employed by managers in seeking an understanding of these elements. The imprisonment of technical aspects is evident throughout the implementation process of the portal, reducing the effectiveness in achieving the AE. The approaches used and the discussion and analysis of the results suggest paths for a possible increase in the understanding of alignment, bringing into consideration the importance of the actors, their practices and praxis, the understanding of the locus of the alignment and their relationships.
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