Thesis advisor: Joseph Quinn / The ease of spread of COVID-19 has posed a great challenge for governments, public health officials, and healthcare workers around the world. Leaders and officials need to make decisions that protect the health and well-being of their citizens, while balancing their rights as citizens and the stability of their economies. This study conducts a review of literature on COVID-19, the Spanish Flu, and the Swine Flu in an effort to understand the economic and health impacts of pandemics. Results show a clear trend suggesting the poor bear a greater burden of the impact of pandemics in regards to economic and health impacts. Further analysis suggests that these inequities are not limited to the United States healthcare system and remain apparent in national single-payer healthcare systems, like in the United Kingdom. To prevent similar disparities in future pandemics, governments should attempt to decrease inequality present in baseline health and economic measures. / Thesis (BA) — Boston College, 2021. / Submitted to: Boston College. College of Arts and Sciences. / Discipline: Department Honors and Scholar of the College. / Discipline: Economics.

Rationing of lifesaving resources in pandemics is likely to be an increasingly relevant issue. While the broad legal and ethical implications of pandemic preparedness have been explored at length, little attention has been paid to the legal issues associated with rationing. This thesis seeks to analyze the potential for administrative and private law challenges to governments’ rationing of vaccines, ventilators and antivirals. The wide variety of statutory authorities, and their associated conditions and discretionary limitations, that governments may rely on for mandating rationing protocols, makes them susceptible to administrative law challenges on the grounds of errors of jurisdiction. An analysis of the tort liability of governments, hospitals and physicians suggests that negligence suits will likely not be successful due to a lack of proximity required for a private law duty of care, the policy-making immunity of governments and a contextual standard of care.

Rationing of lifesaving resources in pandemics is likely to be an increasingly relevant issue. While the broad legal and ethical implications of pandemic preparedness have been explored at length, little attention has been paid to the legal issues associated with rationing. This thesis seeks to analyze the potential for administrative and private law challenges to governments’ rationing of vaccines, ventilators and antivirals. The wide variety of statutory authorities, and their associated conditions and discretionary limitations, that governments may rely on for mandating rationing protocols, makes them susceptible to administrative law challenges on the grounds of errors of jurisdiction. An analysis of the tort liability of governments, hospitals and physicians suggests that negligence suits will likely not be successful due to a lack of proximity required for a private law duty of care, the policy-making immunity of governments and a contextual standard of care.

Objetive: To evaluate the quality of life of older adults who belong to the Seniors Centers (CAM) of the Social Security during the COVID-19 pandemic. Material and methods: Data were collected through telephone calls to older adults aged 60 years and over in the CAM. Quality of life was assessed with the EQ-5D-3L questionnaire, which considers the dimensions of mobility, self-care, activities of daily living, pain/discomfort and anxiety/depression and an analog scale from 0 to 100. The presence of depression, anxiety, comorbidities and functional status were also measured. A bivariate analysis with nonparametric tests was performed to assess the association between covariates and the quality of life analog scale. In addition, a simple regression analysis was performed using generalized linear models of the Poisson family to evaluate variables associated with the presence of problems in the quality of life dimensions. Results: A total of 99 older adults participated, mostly women (84.9%) and with an average age of 73.1 years, 83.3% had a higher education level and 86.7% lived with their spouse. Older adults with obesity, lung disease, inability to manage their own money, feeling fatigued, and hearing problems reported a lower than average score (<78.9) on the analogous quality of life scale. Osteoarticular diseases and feeling fatigued increase the likelihood of having problems with mobility, performing daily activities, and pain/discomfort. Conclusions: Older adults quality of life is influenced by multiple factors that must be addressed to improve their physical and mental well-being. / Revisión por pares

The aim of this thesis is to analyze the reactions and expressions towards the governmental regulations amongst  Swedes in Spain during the Covid-19 pandemic. This is a qualitative online ethnographic case study where a online forum is analysed through a content analysis. The data has been understood through intersectionality theory, biopolitics as outlined by Michel Foucault and Sara Ahmed’s work on the cultural politics of emotions. The analysis identified various themes and as well as emotions circulating around these. Swedes in Spain are expressing their frustration and critique towards illogical and counterproductive regulations as well as showing irritation directed to their freedom of movement being taken away. Frustration and uncertainty are circulating in the discussions. Sociocultural categories such as class, nationality, gender and age as well as how they intensifie each other appear. The Covid-19 pandemic is affecting people in various ways, and the intersectional lens makes it possible to analyse how people depending on their privileges (or lack of) are able to cope with the regulations. This research shows on the importance of an feminist intersectional lens when evaluating the effects of the regulations during the Covid-19 pandemic in each country.

Objetive: To describe the prevention and control practices for the infection to SARS-COV2 in the Peruvian population. Material and Methods: Observational descriptive study. We evaluated a non-probabilistic sample of adult residents in some departments of Peru. Preventive practices were evaluated in people without a history of COVID-19 and control practices in people who had suffered it. Results: We evaluated 3630 Peruvians (mean age 25.4 ± 9.5), of that 3231 don't have a history of COVID-19 and 399 who had suffered it. The prevention and control practices that were realized often or always, with more frequencies, was the use of a mask when they go out home (97.9% vs 87.7), cover their nose or mouth when they sneeze (95.4% vs 89.9%), save the distance to other people in the street (91.4% vs 74.7%), wash their hands when they came home (92.5% vs 88.7%), and disinfect the objects and personal places (82.6% vs 77.4%). The 22.1% and 83.7%, the 59.7% and 80.2, and the 8.0% and 16.8% consumed some type of medicine, medicinal plant, and chlorine dioxide to prevent and control the infection, respectively. Conclusion: In general, less than 50% of the participants performed prevention and control practices against COVID-19 often or always. / Revisión por pares

Yes / Corona Virus Disease 2019 (COVID-19) was declared a global pandemic by the World Health Organization (WHO) has had significant impact on dentistry in Fiji. Due to lack of previous study, this study aims to explore the perspective of Dental Officers (DOs) and Dental Managers (DMs) on the effects of COVID-19 on dental service delivery in Fiji Islands. This qualitative study was conducted amongst 30 DOs and 17 DMs between 9th August to 12th September, 2021. It was conducted in the government dental clinics, private dental clinics and the School of Dentistry and Oral Health clinic (SDOH), in the Central Division, Fiji. The study settings were randomly selected. Purposive sampling method was used for the selection of participants who met the study criteria. Semi-structure open ended questionnaires were used for data collection through in-depth interviews via zoom. Manual thematic analysis of the data was conducted to derive themes and codes. The participants interviewed for the study included more female DOs (66.7%) and male DMs (58.8%). Seven themes emerged from data analysis: range of services delivered, appointment versus walk-in patients for aerosol generating procedures (AGPs), impact of pandemic on clinic opening hours, impact of COVID-19 on patient numbers, quality of services delivered, resources and infrastructure, perceptions about the burden of disease. COVID-19 has significantly affected dental service delivery. Mostly emergency dental services were delivered. AGPs were delivered on appointment basis. Most participants stated the quality of services had improved. Participants stated that they were not given adequate resources and the infrastructure was not up to standard to provide dental services during the pandemic. The dental disease burden had increased during the pandemic as per the participants. Future research can be conducted amongst other dental professionals in other divisions of the country.

There is no overlapping criterion providing a basis for attaining balance between individual and population oriented ethical concerns generated in the pandemic and the epidemic interventions. The shortfall leads to competing individual and population interests that hamper the effective management of pandemics and epidemics. The libertarian model focuses on advancing individual rights. The epidemiological model focuses upon population health. The social justice model focuses on a broader perspective than individual rights and population health to include universal human rights. &lt;br&gt;This dissertation suggests a Mixed Interests Ethics Model (MIEM) to ethically negotiate a balance between the individual and population interests in pandemics and epidemics. MIEM involves a combination of models (libertarian, epidemiological, and social justice) that shed light on substantive ethical principles of each model (e.g. autonomy, solidarity, and common good); which in turn require procedural standards (i.e. necessity, reasonableness, proportionality, and harm avoidance) to negotiate between the principles when they conflict. &lt;br&gt;The UNESCO Universal Declaration on Bioethics and Human Rights provides a hermeneutical context for applying MIEM in so far as it places MIEM within the context of promoting rights (individual and human) by considering the general ethical tension between individual and universal rights as explained by the UNESCO Declaration. / McAnulty College and Graduate School of Liberal Arts; / Health Care Ethics / PhD; / Dissertation;

Introdução: O surgimento de uma nova cepa do vírus Influenza A, o H1N1, determinou uma pandemia no ano de 2009, com importante repercussão global. Esse vírus infectou principalmente adultos jovens e crianças menores de dois anos com grande aumento na morbimortalidade quando comparado com as taxas anuais decorrentes do influenza. Objetivo: Avaliar as características epidemiológicas e clínicas da infecção pelo vírus influenza A (H1N1) em crianças, a fim de agregar conhecimento para melhor abordagem em futuras pandemias. Métodos: Estudo de corte transversal com revisão dos prontuários de todas as crianças, entre zero e 16 anos, hospitalizadas com quadro gripal no Hospital de Clínicas de Porto Alegre (HCPA) em 2009. A identificação do vírus H1N1 foi feita através de Reação em Cadeia da Polimerase (PCR) em laboratório de referência. Resultados: Cento e noventa e uma crianças foram internadas com suspeita de infecção pelo H1N1, destas, 83 (43%) foram submetidos à pesquisa do vírus H1N1, sendo 28 positivos (34%) e 55 negativos (66%). Os pacientes positivos para H1N1 eram mais velhos, 27 (7-108) versus sete (3-32) meses (p=0,015), todos apresentaram febre versus 70% do outro grupo (p=0,015), chegaram ao hospital com menor saturação de hemoglobina, 80% (±20%) versus 95% (±4) (p<0,001) e precisaram de maior pressão expiratória final, dez (±3) versus cinco (±1) cm H2O (p=0,001) e de maior fração inspirada de oxigênio, um (0,65-1) versus 0,4 (0,4-1) (p=0,053) quando colocados em ventilação mecânica. Não houve diferença quanto à necessidade de internação em unidade de terapia intensiva, indicação de suporte ventilatório, tempo de internação e óbito. Conclusão: As crianças acometidas pelo H1N1 apresentaram-se mais graves, embora tenham tido desfechos semelhantes às não infectadas. / Introduction: A new Influenza virus stem, H1N1, determined a pandemic in 2009 with great global repercussions. This virus infected mainly young adults and children under two years of age with marked increase in morbimortality when compared with annual rates. Objective: To analyze epidemiological and clinical characteristics of the infection by influenza A (H1N1) virus in children, in order to improve knowledge to a better approach in future pandemics. Methods: Cross section study with review of patient records for all children, between zero and 16 years, hospitalized with flu-like disease at Hospital de Clínicas de Porto Alegre (HCPA) in 2009. Identification of H1N1 virus was done through PCR technique on reference laboratory. Results: One hundred ninety-one children were hospitalized with suspected H1N1 infection. Of these, 83 (43%) patients were tested for the H1N1 virus, 28 (34%) being positive and 55 (66%) negative. H1N1 patients were older, 27 (7-108) versus seven months old (3-32) (p=0,015), all had fever versus 70% of the other group (p=0,015), they arrived at the hospital with lower oxygen hemoglobin saturation, 80% (±20%) versus 95% (±4%) (p<0,001) and when placed in mechanical ventilation they needed greater end expiratory pressures, ten (±3) to five (±1) cm H2O (p=0,001) and inspired oxygen fraction, one (0,65-1) versus 0,4 (0,4-1) (p= 0,053) . There was no difference in terms of need for hospitalization in intensive care unit, need of ventilatory support or death. Conclusion: Children infected by H1N1 were more severely ill at arrival to the hospital, although they had similar outcomes to non-infected patients.

Introdução: O surgimento de uma nova cepa do vírus Influenza A, o H1N1, determinou uma pandemia no ano de 2009, com importante repercussão global. Esse vírus infectou principalmente adultos jovens e crianças menores de dois anos com grande aumento na morbimortalidade quando comparado com as taxas anuais decorrentes do influenza. Objetivo: Avaliar as características epidemiológicas e clínicas da infecção pelo vírus influenza A (H1N1) em crianças, a fim de agregar conhecimento para melhor abordagem em futuras pandemias. Métodos: Estudo de corte transversal com revisão dos prontuários de todas as crianças, entre zero e 16 anos, hospitalizadas com quadro gripal no Hospital de Clínicas de Porto Alegre (HCPA) em 2009. A identificação do vírus H1N1 foi feita através de Reação em Cadeia da Polimerase (PCR) em laboratório de referência. Resultados: Cento e noventa e uma crianças foram internadas com suspeita de infecção pelo H1N1, destas, 83 (43%) foram submetidos à pesquisa do vírus H1N1, sendo 28 positivos (34%) e 55 negativos (66%). Os pacientes positivos para H1N1 eram mais velhos, 27 (7-108) versus sete (3-32) meses (p=0,015), todos apresentaram febre versus 70% do outro grupo (p=0,015), chegaram ao hospital com menor saturação de hemoglobina, 80% (±20%) versus 95% (±4) (p<0,001) e precisaram de maior pressão expiratória final, dez (±3) versus cinco (±1) cm H2O (p=0,001) e de maior fração inspirada de oxigênio, um (0,65-1) versus 0,4 (0,4-1) (p=0,053) quando colocados em ventilação mecânica. Não houve diferença quanto à necessidade de internação em unidade de terapia intensiva, indicação de suporte ventilatório, tempo de internação e óbito. Conclusão: As crianças acometidas pelo H1N1 apresentaram-se mais graves, embora tenham tido desfechos semelhantes às não infectadas. / Introduction: A new Influenza virus stem, H1N1, determined a pandemic in 2009 with great global repercussions. This virus infected mainly young adults and children under two years of age with marked increase in morbimortality when compared with annual rates. Objective: To analyze epidemiological and clinical characteristics of the infection by influenza A (H1N1) virus in children, in order to improve knowledge to a better approach in future pandemics. Methods: Cross section study with review of patient records for all children, between zero and 16 years, hospitalized with flu-like disease at Hospital de Clínicas de Porto Alegre (HCPA) in 2009. Identification of H1N1 virus was done through PCR technique on reference laboratory. Results: One hundred ninety-one children were hospitalized with suspected H1N1 infection. Of these, 83 (43%) patients were tested for the H1N1 virus, 28 (34%) being positive and 55 (66%) negative. H1N1 patients were older, 27 (7-108) versus seven months old (3-32) (p=0,015), all had fever versus 70% of the other group (p=0,015), they arrived at the hospital with lower oxygen hemoglobin saturation, 80% (±20%) versus 95% (±4%) (p<0,001) and when placed in mechanical ventilation they needed greater end expiratory pressures, ten (±3) to five (±1) cm H2O (p=0,001) and inspired oxygen fraction, one (0,65-1) versus 0,4 (0,4-1) (p= 0,053) . There was no difference in terms of need for hospitalization in intensive care unit, need of ventilatory support or death. Conclusion: Children infected by H1N1 were more severely ill at arrival to the hospital, although they had similar outcomes to non-infected patients.