Class of 2005 Abstract / Objective: To determine what factors rural pharmacists believe affect their ability to counsel patients and provide pharmaceutical care. Subjects: Pharmacy managers in retail pharmacies in rural cities in Arizona (population <30,000). Methods: Questionnaires were administered through phone conversations regarding amount of time spent on counseling, items included in a counsel, views on counseling, factors impacting ability to counsel, patient care services provided, access to educational materials, difficulty and methods of getting time off, number of vacations taken, commute time to work, years working in a rural area and as a pharmacist, and location of college that pharmacists graduated from. Results: Questionnaires were completed by 40 pharmacy managers (80% response rate). Pharmacists that spent more time counseling believed that counseling had a larger impact on patient outcomes that those that counseled less. Those that counseled more had also taken more vacations in the previous ten years. Implications: Pharmacists views on the impact that their counseling has on patient outcomes affects the amount of time they spend on counseling of patients.

Objectives Three objectives were to compare: 1) treatment success; 2) healthcare resource uses; and 3) out-of-pocket (OOP) expenditures, indirect costs, and health-related quality of life (HRQoL) associated with pharmaceutical care, home visit, and modified DOT in three referral hospitals in Songkhla province, Thailand. Methods Project 1&2 were retrospective cohort study collecting data from 1,398 pulmonary TB patients who started treatment between October 2010 and September 2013. Project 3 was a prospective study collecting data from 104 pulmonary TB patients who started treatment between January and May 2014. The propensity score matching and generalized linear models (GLMs) were used to compare the outcomes associated with three supervision approaches by adjusting for baseline characteristics. Results Project1: The differences in treatment success rate were not statistically significant when comparing pharmaceutical care with either home visit (success rate: 92.76% versus 94.74%) or modified DOT (success rate 93.37% for both). Project2: The mean direct healthcare costs to public payer were $519.96 (95% confidence interval (CI): $437.31 to $625.58) for pharmaceutical care, $1,020.39 (CI:$911.13 to $1,154.11) for home visit, and $887.79 (CI:$824.28 to $955.91) for modified DOT. Project3: Mean OOP expenditures were $907.56 (CI:$603.80 to $1,269.41), $148.47 (CI:$109.49 to $194.89), and $95.35 (CI:$69.11 to $129.63), while the indirect costs were $1,925.68 (CI:$922.06 to $3,284.94), $2,393.66 (CI:$1,435.01 to $3,501.98), and $833.33 (CI:$453.87 to $1,263.45), for those receiving pharmaceutical care, home visit, and SAT, respectively. Mean health utility scores at the baseline and the end of treatment were 0.679 and 0.830, 0.713 and 0.905, and 0.708 and 0.913 for the patients receiving pharmaceutical care, home visit, and SAT, respectively. Conclusion Pharmaceutical care is clinically and economically effective compared with the other strategies studied. A large-scale prospective study is warranted to strengthen evidence to support policy making in TB management in Thailand. / Thesis / Doctor of Philosophy (PhD)

Class of 2008 Abstract / Objectives: The purpose of this study is to determine the usefulness of expanded pharmaceutical care services and pharmacist involvement in smoking cessation for patients in a community setting, to identify demographical parameters for the population which might benefit the most from pharmacist intervention, and to examine the cost benefit of such intervention. Methods: This descriptive retrospective study was conducted through a MEDLINE search for all available literature regarding the efficacy of pharmacists in a community setting and smoking cessation outcomes. The results from these studies were then analyzed in order to identify demographic factors which may be associated with higher rates of positive outcome, and the potential cost benefit of such intervention. Information examined from the various articles included: type of study, method of data anaylsis, study/intervention location, patient age, sex, race, other comorbid conditions, and success rates including p values/odds ratios when stated. Results: After the original search, 63 publications were found using MEDLINE, including 12 systematic reviews and 3 clinical trials. After filtering, a total of 28 articles were analzyed. No correlations between demographic factors and successful smoking abstinence were found. All publications, save one, found a positive correlation between higher levels of intervention and increased smoking abstinence rates. Cost effectiveness varied depending on which method of NRT was utilized, ranging from $720 to $2360 per QALY saved. Several national health organizations have published guidelines stating the role of the pharmacist as essential in smoking cessation. Conclusions: Pharmacists have begun to play an essential role in smoking cessation, as evidenced by many successful ventures that have taken place to date. Still, there is vast potential for expansion of pharmaceutical care services in this area.

Type 2 diabetes mellitus is a chronic disease that is associated with substantial morbidity, mortality, and health care cost. All patients with diabetes require a high level of clinical care to prevent the development of diabetic complications. The aim of this study was to compare the impact of a pharmaceutical care diabetic clinic within a primary care setting to standard care on clinical, humanistic and process outcomes in Type 2 diabetes patients. A randomised controlled trial was conducted in 9 general practices in Greater Glasgow Health Board. All patients with Type 2 diabetes, aged 18 years or over, taking an oral antidiabetic drug were recruited and stratified by practice, age, and gender, and then randomised into an active or control group. The patients in both groups were invited to a pharmaceutical care diabetic clinic within their general practice for three visits at three-monthly intervals. Active patients received review and allocated intervention by the pharmacist while control patients received review only without intervention by the pharmacist. Allocation remained blind until after the first evaluation. The pharmacist evaluated the appropriateness of the medication for the individual and their overall diabetic care. The pharmacist prepared a list of drug-related problems and a referral where appropriate. GP referrals were actioned in the active group but held back until after the conclusion of the study in the control group. Patient outcome measures include changes in HbA 1 c value, systolic blood pressure, health related quality of life (HRQOL), and drug related problems (DRPs) from baseline to the end of the study for both groups.

Objetivos: Descrever todo o processo de implantação dos laboratórios de prática de simulação farmacêutica e desenvolver e avaliar um simulador virtual de seguimento farmacoterapêutico adaptando o software SIACC. Métodos: Para a implantação dos laboratórios de prática foi realizado o planejamento da área física, incluindo o fluxo de atividades, identificados os materiais e equipamentos necessários a realização das práticas, os procedimentos que ali serão realizados, bem como a validação dos mesmos, por meio de desenvolvimento, avaliação de realização e correção de desenvolvido. Em relação ao simulador, a metodologia do estudo foi realizada em quatro fases: Fase de planejamento: a adaptação do SIACC para o ensino da prática farmacêutica; Fase de uso do simulador; Desempenho dos usuários; Fase de avaliação do simulador que foi realizada utilizando dois instrumentos de avaliação: ISO 9126 e as Dez Regras de Ouro para avaliação de software. A avaliação foi qualitativa e quantitativa. Na avaliação qualitativa, utilizou-se a Técnica do Grupo Nominal. Resultados: No que se refere a implantação dos laboratórios de prática de simulação, o estudo descreveu todas as etapas da implantação dos laboratórios de prática para a formação do profissional farmacêutico. A avaliação do software com base na ISO 9126 mostrou que não houve diferença estatísticas (p < 0,05) das dimensões avaliadas por dois grupos diferentes: estudantes e especialistas. Também não houve diferença estatística (p < 0,05) das dimensões avaliadas em relação a três grupos: os que não utilizam a informática na educação, os que utilizam apenas para fazer apresentação e os que utilizam mais de um recurso computacional na educação. Na avaliação com base nas Dez Regras de Ouro, apenas dois dos dez itens avaliados tiverem a média < 4 (média máxima: 5,0). Os resultados da avaliação qualitativa corroboraram com a avaliação quantitativa. Conclusões: Estes são os resultados da investigação destinada a desenvolver modelos para a aplicação de métodos de aprendizagem ativos usando novas tecnologias que se destina a ser implementado inicialmente na Escola de Farmácia da UFRGS. / Objectives: The aim was to describe the entire implantation process of the simulation practice laboratories and to develop and evaluate a virtual simulator for pharmacotherapeutic follow-up by adapting IASCC software. Methods: In order to set up the laboratories, the planning of the physical area was carried out to include the flow of activities and the materials and the equipment needed were identified. Also, the procedures that would be done were validated through development and evaluation of achievement and then correction was proposed. In relation to simulator, the methodological development study was conducted in four phases: Planning phase: the adaptation of SIACC for pharmaceutical practice teaching; A second phase using the simulator; and a third consisting of grading the performance of users; and finally, the evaluation of software using two instruments: ISO 9126 and the Ten Golden Rules. The assessment was qualitative and quantitative. In qualitative evaluation, was used the Nominal Group Technique. Results: Regarding the implantation of the simulation practice laboratories, the study described all steps needed to set up laboratories for the training of pharmacists. The evaluation based on the ISO 9126 showed that there was no statistical difference (p < 0.05) between the factors evaluated by two different groups: students and experts in this field. Also, there was no statistical difference (p < 0.05) among the factors evaluated by three groups: those who do not use information technology in education, those who use it only to make presentations and those who use more than one IT resource in education. In the evaluation based on the Ten Golden Rules, only two of the ten items evaluated had an average < 4.0 (maximum average: 5.0). The results of the qualitative evaluation corroborate the quantitative assessment. Conclusions: These are the results of the authors’ research aimed to develop models for the application of active learning methods using new technology to be initially implemented at UFRGS School of Pharmacy.

Objetivos: Descrever todo o processo de implantação dos laboratórios de prática de simulação farmacêutica e desenvolver e avaliar um simulador virtual de seguimento farmacoterapêutico adaptando o software SIACC. Métodos: Para a implantação dos laboratórios de prática foi realizado o planejamento da área física, incluindo o fluxo de atividades, identificados os materiais e equipamentos necessários a realização das práticas, os procedimentos que ali serão realizados, bem como a validação dos mesmos, por meio de desenvolvimento, avaliação de realização e correção de desenvolvido. Em relação ao simulador, a metodologia do estudo foi realizada em quatro fases: Fase de planejamento: a adaptação do SIACC para o ensino da prática farmacêutica; Fase de uso do simulador; Desempenho dos usuários; Fase de avaliação do simulador que foi realizada utilizando dois instrumentos de avaliação: ISO 9126 e as Dez Regras de Ouro para avaliação de software. A avaliação foi qualitativa e quantitativa. Na avaliação qualitativa, utilizou-se a Técnica do Grupo Nominal. Resultados: No que se refere a implantação dos laboratórios de prática de simulação, o estudo descreveu todas as etapas da implantação dos laboratórios de prática para a formação do profissional farmacêutico. A avaliação do software com base na ISO 9126 mostrou que não houve diferença estatísticas (p < 0,05) das dimensões avaliadas por dois grupos diferentes: estudantes e especialistas. Também não houve diferença estatística (p < 0,05) das dimensões avaliadas em relação a três grupos: os que não utilizam a informática na educação, os que utilizam apenas para fazer apresentação e os que utilizam mais de um recurso computacional na educação. Na avaliação com base nas Dez Regras de Ouro, apenas dois dos dez itens avaliados tiverem a média < 4 (média máxima: 5,0). Os resultados da avaliação qualitativa corroboraram com a avaliação quantitativa. Conclusões: Estes são os resultados da investigação destinada a desenvolver modelos para a aplicação de métodos de aprendizagem ativos usando novas tecnologias que se destina a ser implementado inicialmente na Escola de Farmácia da UFRGS. / Objectives: The aim was to describe the entire implantation process of the simulation practice laboratories and to develop and evaluate a virtual simulator for pharmacotherapeutic follow-up by adapting IASCC software. Methods: In order to set up the laboratories, the planning of the physical area was carried out to include the flow of activities and the materials and the equipment needed were identified. Also, the procedures that would be done were validated through development and evaluation of achievement and then correction was proposed. In relation to simulator, the methodological development study was conducted in four phases: Planning phase: the adaptation of SIACC for pharmaceutical practice teaching; A second phase using the simulator; and a third consisting of grading the performance of users; and finally, the evaluation of software using two instruments: ISO 9126 and the Ten Golden Rules. The assessment was qualitative and quantitative. In qualitative evaluation, was used the Nominal Group Technique. Results: Regarding the implantation of the simulation practice laboratories, the study described all steps needed to set up laboratories for the training of pharmacists. The evaluation based on the ISO 9126 showed that there was no statistical difference (p < 0.05) between the factors evaluated by two different groups: students and experts in this field. Also, there was no statistical difference (p < 0.05) among the factors evaluated by three groups: those who do not use information technology in education, those who use it only to make presentations and those who use more than one IT resource in education. In the evaluation based on the Ten Golden Rules, only two of the ten items evaluated had an average < 4.0 (maximum average: 5.0). The results of the qualitative evaluation corroborate the quantitative assessment. Conclusions: These are the results of the authors’ research aimed to develop models for the application of active learning methods using new technology to be initially implemented at UFRGS School of Pharmacy.

Objetivos: Descrever todo o processo de implantação dos laboratórios de prática de simulação farmacêutica e desenvolver e avaliar um simulador virtual de seguimento farmacoterapêutico adaptando o software SIACC. Métodos: Para a implantação dos laboratórios de prática foi realizado o planejamento da área física, incluindo o fluxo de atividades, identificados os materiais e equipamentos necessários a realização das práticas, os procedimentos que ali serão realizados, bem como a validação dos mesmos, por meio de desenvolvimento, avaliação de realização e correção de desenvolvido. Em relação ao simulador, a metodologia do estudo foi realizada em quatro fases: Fase de planejamento: a adaptação do SIACC para o ensino da prática farmacêutica; Fase de uso do simulador; Desempenho dos usuários; Fase de avaliação do simulador que foi realizada utilizando dois instrumentos de avaliação: ISO 9126 e as Dez Regras de Ouro para avaliação de software. A avaliação foi qualitativa e quantitativa. Na avaliação qualitativa, utilizou-se a Técnica do Grupo Nominal. Resultados: No que se refere a implantação dos laboratórios de prática de simulação, o estudo descreveu todas as etapas da implantação dos laboratórios de prática para a formação do profissional farmacêutico. A avaliação do software com base na ISO 9126 mostrou que não houve diferença estatísticas (p < 0,05) das dimensões avaliadas por dois grupos diferentes: estudantes e especialistas. Também não houve diferença estatística (p < 0,05) das dimensões avaliadas em relação a três grupos: os que não utilizam a informática na educação, os que utilizam apenas para fazer apresentação e os que utilizam mais de um recurso computacional na educação. Na avaliação com base nas Dez Regras de Ouro, apenas dois dos dez itens avaliados tiverem a média < 4 (média máxima: 5,0). Os resultados da avaliação qualitativa corroboraram com a avaliação quantitativa. Conclusões: Estes são os resultados da investigação destinada a desenvolver modelos para a aplicação de métodos de aprendizagem ativos usando novas tecnologias que se destina a ser implementado inicialmente na Escola de Farmácia da UFRGS. / Objectives: The aim was to describe the entire implantation process of the simulation practice laboratories and to develop and evaluate a virtual simulator for pharmacotherapeutic follow-up by adapting IASCC software. Methods: In order to set up the laboratories, the planning of the physical area was carried out to include the flow of activities and the materials and the equipment needed were identified. Also, the procedures that would be done were validated through development and evaluation of achievement and then correction was proposed. In relation to simulator, the methodological development study was conducted in four phases: Planning phase: the adaptation of SIACC for pharmaceutical practice teaching; A second phase using the simulator; and a third consisting of grading the performance of users; and finally, the evaluation of software using two instruments: ISO 9126 and the Ten Golden Rules. The assessment was qualitative and quantitative. In qualitative evaluation, was used the Nominal Group Technique. Results: Regarding the implantation of the simulation practice laboratories, the study described all steps needed to set up laboratories for the training of pharmacists. The evaluation based on the ISO 9126 showed that there was no statistical difference (p < 0.05) between the factors evaluated by two different groups: students and experts in this field. Also, there was no statistical difference (p < 0.05) among the factors evaluated by three groups: those who do not use information technology in education, those who use it only to make presentations and those who use more than one IT resource in education. In the evaluation based on the Ten Golden Rules, only two of the ten items evaluated had an average < 4.0 (maximum average: 5.0). The results of the qualitative evaluation corroborate the quantitative assessment. Conclusions: These are the results of the authors’ research aimed to develop models for the application of active learning methods using new technology to be initially implemented at UFRGS School of Pharmacy.

A hipertensão arterial sistêmica é uma doença crônica em que a pressão arterial do indivíduo permanece acima de 140/90 mmHg. Ela afeta aproximadamente 70 milhões de pessoas nos EUA e 1 bilhão de pessoas em todo o mundo (ONG et al, 2007). Essa enfermidade pode levar a complicações, das quais se pode destacar o infarto agudo do miocárdio e o acidente vascular cerebral. Estudos têm demonstrado que a atenção farmacêutica pode auxiliar na obtenção de resultados clínicos importantes, como a redução da pressão arterial (ERICKSON; SLAUGHTER; HALAPY, 1997; ZILLICH et al. 2005), entretanto os recursos limitados impedem a garantia de um atendimento farmacêutico adequado a todo paciente que utiliza medicamentos. Diante do exposto, o presente estudo tem como finalidade desenvolver e avaliar um formulário para a seleção de pacientes hipertensos e inclusão destes junto a um serviço de AtenFar, bem como analisar a efetividade deste durante o período de acompanhamento e após a alta desses pacientes. Esse estudo foi dividido em quatro fases, sendo elas: fase de desenvolvimento do INSAFHAS, fase de seleção, fase de acompanhamento, e fase de alta. Em adição, os sujeitos da pesquisa foram divididos de acordo com a pontuação obtida no instrumento (G1 - maior pontuação, G2- menor pontuação) e os usuários de cada grupo foram randomizados em outros dois grupos, sendo eles, Controle (C) e Experimental (E). Com isso, obteve-se um total de quatro grupos (G1C, G1E, G2C, G2E), sendo que os sujeitos dos grupos experimentais foram incluídos em um serviço de atenção farmacêutica e acompanhados em atendimentos mensais por doze meses. Observou-se que os sujeitos do grupo 1 apresentavam idade superior, menor escolaridade, valores superiores de pressão arterial sistólica e de glicemia de jejum e menor conhecimento relativo ao tratamento medicamentoso. Verificou-se ainda, ao final da fase de acompanhamento, redução da pressão arterial no G1E e redução no IMC, aumento da adesão ao tratamento medicamentoso e do conhecimento relativo ao tratamento medicamentoso no G2E. Na fase de alta houve aumento da pressão arterial em todos os grupos, porém não foram observadas evidências científicas de que esse aumento era significativo. Sendo assim, pode-se concluir que o instrumento elaborado foi adequado para a seleção de indivíduos para um serviço de atenção farmacêutica, e que o mesmo promoveu melhoras clínicas nos hipertensos. Porém novos estudos a respeito da alta dos usuários precisam ser realizados. / Hypertension is a chronic disease in which blood pressure remains above 140/90 mmHg. It affects approximately 70 million people in the United States and 1 billion people worldwide (ONG et al, 2007). This disease may lead to complications, such as, we can highlight acute myocardial infarction and stroke. Studies have shown that pharmaceutical care can help to achieve important clinical outcomes, such as reduced blood pressure (ERICKSON; SLAUGHTER; HALAPY, 1997; ZILLICH et al 2005). However limited resources hinder the assurance of an appropriate pharmaceutical service to every patient who uses drugs. Therefore this study aims to develop and evaluate a form for selection of hypertensive patients and inclusion of these patients into a pharmaceutical care service as well as analyzing the effectiveness of this service during the follow-up period and after discharge. This study was divided into four phases, namely: development of the INSAF-HAS phase, selection phase, follow-up phase, and discharge phase. Subjects were divided according to the score obtained in the form (G1 - highest score, G2 - lowest score). Patients in each group were randomized into two groups, namely, Control (C) and Experimental (E), so we obtained a total of four groups (G1C, G1E, G2C, G2E). By the way subjects in experimental groups were included in a pharmaceutical care service and followed-up at monthly visits for twelve months. We found higher age, lower education, higher systolic blood pressure and fasting glucose, slightest knowledge on the medical treatment in Group 1 than Group 2. At the end of follow-up phase it was found lowering blood pressure in G1E and reduction in BMI, increased adherence to drug therapy and knowledge relating to drug therapy at G2E. In the discharge phase there was increased BP in all groups, but evidence was not observed that this increase was significant. Thus, it could be conclude that the instrument was appropriate for screening individuals for a pharmaceutical care service, and the pharmaceutical care service promoted clinical improvement in hypertensive patients. Even so new studies about the discharge are required.

O diabetes é uma doença crônica, caracterizada pelo aumento dos níveis glicêmicos, podendo levar a complicações, como neuropatia, retinopatia e nefropatia. O profissional farmacêutico possui fundamental papel no controle da doença, sendo responsável pela farmacoterapia, capaz de identificar e resolver problemas relacionados a medicamentos, proporcionar maior adesão ao tratamento e consequente melhoria dos parâmetros clínicos. Com aumento das necessidades em saúde e a disponibilidade finita de recursos, os gestores devem avaliar se tecnologias em saúde são tanto eficazes quanto econômicas. Dessa forma, este trabalho teve como objetivo geral analisar a relação custo efetividade da atenção farmacêutica no tratamento do diabetes mellitus tipo 2. Para tanto, descreveu os principais métodos de avaliação econômica em saúde e baseado nos dados dos estudos de Borges (2008) e Pereira (2012) como, dados clínicos de hemoglobina glicosilada e glicemia de jejum, bem como consumo de medicamentos, número de consultas, além de dados referentes a complicações do diabetes, este trabalho valorizou os custos diretos e indiretos e mensurou as efetividades para controle da glicemia de jejum, controle da hemoglobina glicosilada e anos de vida ganho, segundo tratamento convencional (grupo controle) e tratamento convencional associado a atenção farmacêutica (grupo atenção farmacêutica). Sendo assim, conclui que a atenção farmacêutica exibiu, para o período de 2007 a 2011, maior efetividade para os parâmetros de glicemia de jejum, hemoglobina glicosilada e anos de vida ganhos, associado a menores custos quando comparada ao grupo controle, sendo a alternativa com menor custo efetividade para o tratamento de diabetes mellitus tipo 2, estando posicionada no quadrante dominante \"D\" do diagrama de custo efetividade incremental. / Diabetes is a chronic disease characterized by increased blood glucose levels, which can lead to complications such as neuropathy, retinopathy and nephropathy. Pharmacists has key role in controlling the disease and is responsible for pharmacotherapy, able to identify and resolve drug-related problems, providing greater adherence to treatment and consequent improvement of the clinical parameters. The increase in health needs and the finite availability of resources, managers should assess whether health technologies are both effective as economic. Thus, this study aimed to analyze the cost effectiveness of pharmaceutical care in the treatment of diabetes mellitus type 2. Therefore, described the main economic evaluation methods in health and based on data from Borges studies (2008) and Pereira (2012) as clinical data glycosylated hemoglobin and fasting glucose, and medication consumption, number of visits, as well as data for diabetes complications, this study valued the direct and indirect costs and measured the effectivities for fasting glycemic control, glycosylated hemoglobin control and years of life gained, according to conventional treatment (control group) and conventional treatment associated with pharmaceutical care (pharmaceutical care group). Therefore, concludes that the pharmaceutical care exhibited for the period 2007-2011, more effective for fasting glucose parameters, glycosylated hemoglobin and years of life gained, combined with lower costs when compared to the control group, and the alternative lower cost effectiveness for the treatment of diabetes mellitus type 2, being positioned in the dominant quadrant \"D\" from the incremental cost effectiveness diagram.

No período de 2008 a 2010, foi realizado o estudo de Atenção Farmacêutica, prospectivo longitudinal, com a participação de 104 pacientes diagnosticados com hipertensão arterial sistêmica, oriundos de duas unidades de saúde, do Distrito Sanitário Oeste da Cidade de Ribeirão Preto/SP. Após seis meses de estudo houve redução estatística significativa nos valores de Pressão Arterial Sistólica e Diastólica com menor dispersividade dos valores e clínica. A adesão ao tratamento aumentou ao longo do acompanhamento. Apresentou-se reduzido risco cardiovascular, com uma redução estatisticamente significativa do escore de risco Framingham. Discreta redução dos atendimentos de emergência. Apesar do sucesso deste estudo, fica em aberto se os benefícios alcançados são considerados transitórios ou permanentes. Para tanto, os pacientes foram reavaliados quanto aos parâmetros: pressão arterial sistólica e diastólica; valores de colesterol total; HDL; LDL, triglicerídeos, número de consultas em geral realizadas nessas unidades de saúde, e número de princípios ativos utilizados. Comparados os dados no período durante e após a Atenção Farmacêutica observou se que houve um aumento estatisticamente significante nos valores de pressão arterial sistólica e diastólica Com relação aos números de medicamentos prescritos houve também um aumento estatisticamente significativo, mas justificável devido à alteração na relação municipal de medicamentos essenciais entre os anos de 2009 e 2012. Quanto ao número de consultas e os resultados dos exames laboratoriais não houve diferença estatisticamente significante. Diante disso, pode se concluir que a Atenção Farmacêutica foi importante para a manutenção e manejo dos pacientes hipertensos e que o período de 30 meses após a Atenção Farmacêutica apresentou discretas alterações, principalmente nos valores de pressão arterial sistólica e diastólica e número de princípios ativos utilizados. / In the period from 2008 to 2010, a longitudinal and prospective Pharmaceutical Care study was conducted with 104 patients diagnosed with hypertension, from two health units, from the West Sanitary District of the municipality of Ribeirão Preto/SP. In this study, in the first six months of follow-up was observed a statistically and clinically significant reduction in the values of systolic and diastolic blood pressure, and with less dispersivity values. Medication adherece increased during the follow-up, a lower coronary risk was presented, with a statistically significant reduction in the Framingham Risk Score. A slight reduction in the emergency room visits was also observed. Considering the success of this study, was not decide whether the benefits obtained were considered transitory or permanent. Therefore patients were reassessed for the parameters: systolic and diastolic blood pressure; total cholesterol; HDL, LDL, triglycerides, number of consultations in general performed in those health units, and number of active moieties. Comparing data from the period during and after the Pharmaceutical Care, it was observed that there was a statistically significant increase in systolic and diastolic blood pressure. Regarding the number of prescribed medications statistically significant increase was also observed, but justifiable due to changes in the municipal list of essential medicines between the years of 2009 and 2012. Regarding the number of medical appointments and the results of laboratory tests there was no statistically significant difference. Thus, it can be concluded that Pharmaceutical Care was important for the maintenance and management of hypertensive patients and that the period of 30 months after the Pharmaceutical Care showed slight alterations, mainly in systolic and diastolic blood pressure and number of active moieties used.