The purpose of this pilot study was to examine the benefit of offering a percussion ensemble class in secondary public schools. I looked at two elements of music education: playing time and relevant instruction. The research questions focused on the difference in playing time and relevant instruction between percussionists in the concert band and percussionists in the percussion ensemble, as well as differences between the concert band subgroups (brass, woodwind, percussion). 6 separate instrumental groups were observed: 4 concert bands and 2 percussion ensembles (N=6). Students were randomly selected from each instrument subgroup (brass, woodwind, percussion, percussion ensemble) for observation. A mixed model ANOVA was used to compare the playing time per hour of each instrument subgroup. A second mixed model ANOVA was used to compare the relevant instruction received per hour of each instrument subgroup. As anticipated, the concert band percussionists experienced significantly less playing time and relevant instruction than both the brass and woodwind subgroups. The percussion ensemble subgroup did not experience a significant difference in either playing time or relevant instruction from the concert band percussionstudents. However, informal observations of the rehearsals indicated a difference in the scope and depth of the playing time and instruction experienced by these two subgroups. Implications from these observations are also discussed.

The nursing profession perpetuates an outdated model that fails to address the health concerns of racialized gender-diverse people. Evidence supports that this population experiences poorer health outcomes, care-avoiding habits, and incompetent healthcare providers. A literature review illuminated gaps in the nursing lens when considering gender-diverse identities outside of Whiteness. An intersectionality framework and cultural humility were used to explore the contexts in which nurses provide care. To fill this knowledge gap, the proposed research question was: How prepared are nurses to provide care to racialized gender-diverse people? A questionnaire was developed by modifying three pre-existing instruments. The online questionnaire served as a pilot feasibility study to collect preliminary baseline descriptive cross-sectional data about Ontario nurses' training, education, knowledge, attitudes, and beliefs about racialized gender-diverse people. Findings indicated potential gaps in training and education that may affect racialized gender-diverse peoples' healthcare. Recommendations are provided for future research and interventions.

This pilot study investigated the efficacy of a supplemental Active Learning intervention that was administered with grammar workbook software in remedial-level composition classrooms at Seminole State College. The study analyzed student response data in a pre-test and post-test instrument in four classrooms; two followed standard methods while two incorporated the additional experimental intervention. The groups are identified in this study as either “Standard” or “Experimental,” according to the method administered in the classroom. The intervention was designed based on five grammar topic areas which correspond with content assessed in the pre-test and post-test. The Active Learning method required students to prepare a short, guided presentation on selected grammar topics. Findings showed that there was no significant change in improvement between the pre-test and post-test among the Standard or the Experimental groups, due in part to a relatively small sample size. A positive change approaching significant level occurred in the Experimental group in topic areas related to critical thinking. No significant or near-significant change was observed in the topic areas related to memorization in either group. Recommendations were made for further sampling, modification, and future applications of the intervention used in the study and for continued testing of grammar software used for instruction in Developmental Writing classes at Seminole State College.

The causality dilemma between dysbiosis and cancer has given rise to numerous studies both exploring the mechanisms behind cancer progression and the associative shifts in the microbiota upon carcinogenesis. Aside from the hallmark study of Dr. Barry Marshall in establishing the true causal relationship between Helicobacter pylori and gastric adenocarcinoma, studies have only been successful in adding associative links of carcinogenesis mediated by bacteria to the literature. The current field is limited in its ability to establish causative relationships, and further work is needed to construct a reference community whose physiological responses reflect global community responses. In this thesis, the organism Lactobacillus acidophilus was selected as a pilot strain for the development of a novel framework to establish the fitness and physiological changes that occur when bacteria engage the human epithelial environment. The pilot strain was revived from the American Type Culture Collection (ATCC), verified through 16S rRNA Sanger sequencing, and grown in its conventional culture medium and human tissue culture medium to establish baseline growth rates and gauge its physiological responses to an in vitro tumor microenvironment. A set of standard conditions was proposed for growth under human tissue culture conditions. Finally, a metabolic study and spot plate assay were performed to elucidate the anabolic deficits and viability of this strain in human tissue culture medium, respectively. This research was performed to better understand the environmental and metabolic requirements for this pilot strain to inhabit the human epithelial environment, and to establish a workflow that will set the foundation for an appropriate clinical study to demonstrate the causative relationship between dysbiosis and carcinogenesis.

No description available.

Psykosociala faktorer kännetecknar allt som inte berör fysiska omständigheter på en arbetsplats. En god psykosocial arbetsmiljö ses bland annat när det råder goda relationer med arbetskamrater och när ansvars- och beslutstagande möjliggörs. Eftersom det i dagsläget råder otillräcklig information inom området är syftet med denna studie att ta fram och utforma en enkät med frågor som berör tandhygienistens psykosociala arbetsmiljö. Frågorna i enkäten kommer att konstrueras utifrån de redan etablerade frågorna i Copenhagen Psychosocial Questionnaire, COPSOQ. Enkäten ska sedan prövas i en pilotstudie. Efter utförd pilotstudie redovisas respondenternas kommentarer på enkätens innehåll och disposition. Resultatet visar att frågorna i COPSOQ innehåller en del svagheter vad avser formulering och innebörd. För enkäten som helhet har både fördelar och nackdelar påträffats. Slutsatsen blir därför att enkäten inför eventuellt framtida ändamål bör bearbetas och förtydligas innan den realiseras. / Psychosocial factors characterize everything that does not concern physical circumstances at a workplace. A good psychosocial work environment is exemplified by good relations with colleagues and the possibility of taking responsibility and making decisions. The information regarding the dental hygienist psychosocial work environment is insufficient. The aim of this study is therefore to develop and design a questionnaire within the given subject. The questionnaire will be based on established questions in the Copenhagen Psychosocial Questionnaire, COPSOQ. The questionnaire will then be tested in a pilot study. The pilot study will present the respondents comments on the questionnaire, in terms of its content and presentation. Results show that the questions in COPSOQ contain some weaknesses regarding formulation and meaning. For the survey as a whole, both advantages and disadvantages were encountered. It is therefore concluded that the questionnaire for any future purpose should be reworked and refined before application.

<p><strong>Background and objectives</strong>: Physiotherapists provide conservative treatment for neck pain utilizing manual therapies (MT), including spinal manipulation. Adverse events (AE) have been associated with manipulation provided mainly by other professions. Physiotherapy specific data are lacking. Definitions of AEs following MT require clear standardized criteria informed by both practitioners and patients. The objectives of this thesis were to: a) establish practice patterns of spinal manipulation in Canadian manipulative physiotherapists (CMPTs), b) establish patients’ perceptions of an AE related to MT and c) pilot the collection of AE data reported by practitioners and patients. <strong>Methods</strong>: For the first objective, multiple linear regression of survey data determined the association between experience and frequency of use of manipulation amongst CMPTs. For the second objective, Poisson regression identified predictors of patients more likely to report the occurrence of an AE. The final objective utilized descriptive statistics of patient and practitioner reported AE to assess feasibility for a future large-scale study. <strong>Results</strong>: For the first, increased experience was associated with increased use of upper cervical manipulation in males (14% more often for every 10 years after certification; beta 1.37, (95% confidence interval) (0.89,1.85) pConclusion: Manipulation by CMPTs remains a valued option as experience increases. Adverse events reported by patients are influenced by expectations. A large cohort study attempting to accurately define and measure AE rates following manipulation will be challenging to perform in private practice settings.</p> / Doctor of Philosophy (PhD)

Blood sampling causes significant blood loss in intensive care unit (ICU) patients (up to 41 mL per day). Only 10% of the blood collected is used for testing suggesting that volumes can be reduced without compromising patient care or laboratory processes. Blood loss contributes to anemia which is highly prevalent in the ICU (>90% after 3 days) and is associated with major adverse cardiovascular outcomes and death. Diagnostic blood loss increases the likelihood of red blood cell (RBC) transfusion which is administered to about 40% of ICU patients (half are given in absence of hemorrhage) and has significant health risks. Small-volume blood collection tubes, which collect about 50% less blood, are available, but rarely used in adults. They have the same cost as standard-volume tubes and are compatible with laboratory equipment. The rationale for the continued use of standard-volume tubes is a theoretical concern about inadequate volume for testing, and the absence of data showing the benefit of small-volume tube use on an important clinical outcome. A study is needed to show that small-volume tubes reduce blood loss, anemia and RBC transfusion without harms or negative consequences on patient care and hospital procedures compared to standard-volume tubes. If this could be shown, it may lead to practice change regarding blood collection for laboratory testing. A stepped-wedge cluster randomized trial is the ideal study design for this low-risk intervention. By incorporating the small-volume tubes into routine clinical practice and using administrative and hospital electronic medical record data, this study would be a pragmatic, cost-effective way to evaluate effectiveness and implementation. However, prior to conducting a full-scale trial powered on clinical outcomes, a pilot study is needed to determine whether a larger study will be feasible. The goals of this thesis are to (i) summarize the existing evidence regarding small-volume tubes; (ii) discuss cluster randomized trial methodology;(iii) discuss the use of health care administrative data for research; (iv) discuss the role of pilot studies; and (v) present the design of a pilot stepped wedge randomized trial of small-volume versus standard-volume blood collection tubes to evaluate the feasibility of a full-scale trial. / Thesis / Master of Science (MSc) / Blood testing is a preventable cause of blood loss. Patients in the intensive care unit (ICU) have about 41 mL of blood taken per day for testing (like donating 1 unit of blood every 8 days). This contributes to anemia (low red blood cells) and transfusion, which are harmful. About 40% of ICU patients get at least one red blood cell transfusion which is a limited resource with health risks. Most of the blood sent to the laboratory is discarded (up to 90%) suggesting that volumes can be reduced without compromising care. The goals of this thesis are to (i) summarize the evidence for reducing blood loss for laboratory testing; (ii) discuss cluster randomized trials; (iii) discuss use of health care administrative data for research; (iv) discuss the role of pilot studies; and (v) present a pilot stepped wedge cluster randomized trial of small-volume versus standard-volume blood collection tubes in ICU patients.

Vårt examensarbete har genomförts på företaget Electrolux Laundry Systems (ELS) logistikavdelning, Logistics Center Ljungby (LCL).  Under det senaste året har företaget haft motgångar vid ett IT/IS-projekt inom sin logistikavdelning (LCL). Uppsatsen har således syftat till att beskriva och analysera varför IT/IS-projektet har avstannat, och ej nått implementering. För att uppnå syftet har vi utgått från en, i stort sett, kvalitativ ansats där primärdata har insamlats genom metoder såsom intervjuer och deltagande observationer medan sekundärdata inhämtats i form av dokumentundersökningar och offentliga dokument.   Resultatet av studien har utgjorts av deltagande observationer på fallföretagets logistikavdelning, LCL, samt intervjuer med olika verksamhetsnivåer. Detta har påvisat bristande kommunikation och direktiv samt fallföretagets brister i förstudiens utförande vad gäller förankring av projektet, planering av tid, resurser och kostnader samt formulering av krav. Slutsatser vi kunnat dra av detta är att en fungerande kommunikation mellan olika verksamhetsnivåer samt en noggrant utförd förstudie är essentiella element för att ge ett projekt rätt förutsättningar. / Our thesis has been performed in the company of Electrolux Laundry Systems (ELS) logistics department, Logistics Center Ljungby (LCL). Over the past year, the company has met setbacks during an IT/IS-project in the logistics department (LCL). The essay is thus aimed to describe and analyze why the IT/IS-project have stagnated. To achieve the purpose of the study we have applied a mainly qualitative approach in which the primary data is collected through methods such as interviews and participant observations while the secondary data is obtained by means of litterature and public documents.   The study’s result consisted of participant observation at LCL, and interviews with co-workers at various levels in the organization. These have shown a lack of communication between employees at different levels in the company. Moreover, the result proved the company's shortcomings in designing the pilot study, e.g. deeply root the project, planning time, resources, costs and specify requirements. Our conclusions from this study are that effective communication between different levels of employees, and an accurately performed pilot study, are essential elements to give a project the right conditions.

In der randomisierten, multizentrischen DASH-Studie (Dietary Approaches to Stop Hy-pertension), die unter kontrollierten Bedingungen stattfand, führte eine fettreduzierte Mischkost, reich an Obst, Gemüse und Milchprodukten, bei Borderline-Hypertonikern zu einer signifikanten Blutdrucksenkung. Während der Studienphase wurden Körpermasse, Natrium-Aufnahme sowie Alkoholzufuhr aufgrund der bekannten Einflussnahme auf den Blutdruck konstant gehalten. In der eigenen Pilot-Studie sollte untersucht werden, ob das Ergebnis der DASH-Studie (i) mit deutschen Hypertonikern und (ii) unter habituellen Ernährungs- und Lebensbedingungen mit regelmäßig durchgeführter Ernährungsberatung und ad libitum Verzehr anstelle des streng kontrollierten Studienansatzes bestätigt werden kann. Eine Konstanz der Körpermasse, der Natrium-Urinausscheidung (unter diesem Studienansatz valider als die Aufnahme) und des Alkoholkonsums wurde vorausgesetzt.<br /> Die Studienpopulation setzte sich aus 53 übergewichtigen Probanden mit einer nicht medikamentös therapierten Borderline-Hypertonie und ohne Stoffwechselerkrankungen zusammen. Die Studienteilnehmer wurden randomisiert entweder der Idealgruppe mit einer fettarmen Kost reich an Milchprodukten, Obst und Gemüse (ähnlich der DASH-Idealgruppe) oder der Kontrollgruppe mit habitueller Ernährungsweise zugeteilt. Über einen Zeitraum von fünf Wochen wurde den Probanden etwa 50% ihres täglichen Lebensmittelbedarfes entsprechend ihrer Gruppenzugehörigkeit kostenfrei zur Verfügung gestellt. Gelegenheitsblutdruckmessungen und 24h-Blutdruckmessungen, Ernährungs- und Aktivitätsprotokolle, Blut- und Urinproben sowie anthropometrische Messungen wurden vor, während und fünf Wochen nach der Interventionsphase durchgeführt.<br /> Die Ergebnisse zeigen, dass in der Idealgruppe keine signifikante Blutdrucksenkung beobachtet werden konnte. Dies lässt sich durch die Tatsache erklären, dass die Lebens-mittel- und Nährstoffaufnahme der deutschen Kontrollgruppe eher der amerikanischen Idealgruppe entsprach. In der Pilot-Studie waren die Unterschiede in der Nährstoffzufuhr zwischen den beiden Gruppen viel geringer als in der DASH-Studie; für eine blutdrucksenkende Ernährungsumstellung bestand somit nur ein geringer Spielraum. Eine weitere Erklärung besteht in der unterschiedlichen Zusammensetzung der Studienpopulation. Bei DASH wurden vorwiegend farbige Probanden (40% höhere Hypertonieprävalenz) untersucht. Die Studienergebnisse lassen also den Schluss zu, dass Ernährungs- und Lebensstilgewohnheiten sowie der genetische Hintergrund der entsprechenden Bevölkerungsgruppe bei der Formulierung von nährstoff- oder lebensmittelbezogenen Empfehlungen zur Senkung des Bluthochdruckes Berücksichtigung finden müssen. / The Dietary Approaches to Stop Hypertension trial (DASH), a randomized well-controlled feeding study conducted at 4 medical centers, demonstrated that a low-fat diet, rich in fruits, vegetables and dairy products is able to lower blood pressure of borderline-hypertensive people significantly. Body weight, sodium intake and alcohol consumption were kept constant during the whole study period, due to the known influence on hypertension. Aim of our study project was to investigate whether the results of the DASH study can be confirmed by (i) using a German hypertensive population and (ii) replacing the well-controlled feeding design by allowing ad libitum intake according to dietary ad-vice. The participants were asked to keep their body weight, sodium urine excretion (un-der this study design more valid than sodium intake) and their alcohol consumption con-stant.<br /> Our pilot study population consisted of 53 mainly overweight participants with borderline hypertension and without medication or any metabolic disorders. They were randomly assigned to either an ideal diet low in fat and rich in dairy products, fruits and vegetables (similar to the DASH I-group) or a habitual diet as control (C-group). During five weeks the subjects were provided 50 % of their daily intake for free according to their dietary pattern. Single and 24h-blood pressure measurements, dietary weighed and physical activity records, blood and urine samples and anthropometric measurements were collected before, during and five weeks after the intervention period.<br /> The study results indicated that no significantly reduction of blood pressure could be observed for both methods in the I-group of our trial. This is due to the fact that the baseline intake of foods and nutrients of the German subjects was nearly corresponding to the intake targeted for the DASH I-group. Therefore, it was impossible to increase the intake of these nutrients in our I-group by the same percentage as in the DASH study. Another explanation may be the different consistency of the study population. About 60% of the DASH study population were African Americans with a known higher prevalence of hy-pertension (about 40%) than Caucasians.<br /> The conclusion is that even convincing results of a controlled trial cannot be simply transferred into dietary advice for the general public. For addressing food-based dietary guidelines to reduce the risk of hypertension it is necessary to consider the genetic background as well as the dietary and the lifestyle situation of the target population carefully.