Vinte e nove pacientes submetidos ao Transplante de Medula Óssea Alogênico foram analisados num estudo dirigido às transfusões de hemocomponentes, desde o período pré-transplante até o momento da alta hospitalar, que na maioria das vezes coincidiu com a independência às transfusões. Não houve um padrão único de requerimento transfusional e os fatores que determinaram este fato foram múltiplos. O tipo de doença de base, intercorrências clínicas e a presença da Doença do Enxerto Versus o Hospedeiro estiveram relacionados. As técnicas laboratoriais empregadas na rotina de avaliação dos pacientes ofereceram subsídio adequado, para em conjunto com o exame clínico, proporcionarem parâmetros decisivos na indicação das transfusões sangüíneas. Alguns pacientes apresentaram incompatibilidade ao sistema de grupo sangüíneo ABO com os seus respectivos doadores de medula, fato que não impediu a realização do transplante, devido ao emprego de métodos que permitiram superar esta dificuldade. Foi observada refratariedade às transfusões de concentrados de plaquetas em poucos pacientes da casuística, atribuída à presença de anticorpos contra antígenos do sistema de histocompatibilidade leucocitária humana (HLA). As transfusões de plaquetas obtidas de doadores com o sistema HLA compatível, membros familiares, foram eficazes nestes casos. O tempo de recuperação da função hematopoética da medula transplantada foi similar ao descrito na literatura. / 29 patients who underwent Allogeneic Bone Marrow Transplantation (Allo BMT) were analyzed regarding the need for transfusion of blood components from admission the date of discharge. Most of the time the discharge coincided with blood components transfusion independence. There was no specific pattern of blood products transfusion among these patients. The need for transfusion could be ascribed to the presence of several factors like baseline disease, clinical complications and graf versus host disease. Routine clinical parameters and laboratory techiniques were adequate to indicate the need for transfusion of blood components. Some of the patients were ABO incompatible with their respective marrow donors. We observed no adverse consequence for the outocome of these BMT procedures after the use of routine techiniques to overcome this incompatibility. Few patients were refractory to platelet transfusions that was ascribed to HLA directed antibodies. The use of HLA compatible platelet donors (family members) provided adequate platelet support in these cases. The time to hematopoietic recovery was compatible to the found in the international literature.

RESUMO O objetivo deste estudo foi avaliar o conhecimento de cirurgiões dentistas inscritos em cursos de estética quanto aos fatores predisponentes e de diagnóstico do câncer bucal, a partir de um questionário previamente testado. O desenvolvimento de materiais e técnicas odontológicas e o anseio cada vez maior do ser humano em busca da beleza têm levado um número crescente de pacientes aos consultórios odontológicos. Julgamos este momento oportuno para informar a população e diagnosticar precocemente o câncer de boca. Com relação às características gerais dos 465 participantes, houve predominância de uma população jovem, com idade inferior a 39 anos, maior participação feminina e quase 1/3 formados de 10 a 20 anos. As características clínicas da ocorrência desta neoplasia não estão claras para os entrevistados, uma vez que somente metade indicou o carcinoma espinocelular como o tipo mais comum, e aproximadamente metade tem conhecimento das características do linfonodo em metástase cervical. Cerca de 20% desconhece a região da boca e a faixa etária de maior ocorrência deste tumor, e também o seu aspecto inicial. Entretanto, 75,7% reconhecem a leucoplasia como a condição mais comumente associada ao câncer bucal. Com relação aos fatores de risco, o consumo de tabaco, história familiar e consumo de álcool estão claros para quase todos os participantes, mas, em se tratando das demais condições apresentadas como fatores de risco, as dúvidas e contradições estão evidentes. Na prática clínica relacionada ao câncer de boca, observa-se que 14,2% não realizam exames para identificar lesões bucais, sendo que, destes, 80,3% não sabem como fazê-lo. Apenas 5,8% realizam procedimentos de diagnóstico, com a grande maioria considerando regular ou insuficiente seu conhecimento na área. Somente 16,6% têm confiança para realizar o diagnóstico. Mais da metade está há mais de 5 anos sem realizar um curso de atualização em câncer de boca, apesar de terem interesse em faze-lo no futuro. Concluindo, os cirurgiões dentistas ainda não apresentam conhecimento e treinamentos ideais para difundir os meios de prevenção e detecção precoce do câncer de boca. / ABSTRACT The purpose of this paper is assessing the knowledge of dentists who are registered at aesthetics courses as for predisposing and diagnosis factors of oral cancer, through a previously tested questionnaire. The development of odontological materials and techniques allied to a longing of a human being who is more and more in search of beauty, has taken an increasing number of patients to odontoligical consultation rooms. We consider this an opportune moment to inform the population and to do the early diagnosis of oral cancer. On what concerns the general characteristics of the 465 participants, there was a predominance of a young population, whose age was under 39 years, more female participation and almost 1/3 who had been graduated for 10 to 20 years. The clinical characteristics of this neoplasia occurrence are not clear for the persons interviewed, since only half of them have indicated the spinocellular carcinoma as the most common one and approximately half of them are aware of the lymph node characteristics in cervical metastasis. Around 20%, ignores the region of the mouth and the age group where this tumor occurs more frequently, and also its initial aspect. Notwithstanding, 75,7% recognizes the leucoplasia as the condition more frequently associated with oral cancer. On what concerns risk factors, the use of tobacco, family history and alcohol intake are clear for almost all the participants, but on what refers to the other conditions presented as risk factors, the doubts and contradictions are evident. On the clinical practice related to oral cancer, it is observed that 14,2% don’t do examinations for identifying buccal lesions, and among these ones, 80,3% don’t know how to do it. Only 5,8% does diagnosis procedures, and the great majority considers their knowledge in the area, regular or insufficient. Only 16,6% has enough confidence to do the diagnosis. In spite of being interested in doing courses in the future, more than half of them have not taken any upgrading course on oral cancer for more than 5 years. Concluding, the dentists still don’t present ideal knowledge and training to diffuse the means for prevention and early detection of mouth cancer.

Orientador: Plínio Trabasso / Texto em português e inglês / Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas / Made available in DSpace on 2018-08-25T16:43:11Z (GMT). No. of bitstreams: 1 Madeira_MariaZeliadeAraujo_M.pdf: 1405070 bytes, checksum: 92d0a92bffeb8403785ffcb448a2afbb (MD5) Previous issue date: 2014 / Resumo: INTRODUÇÃO: As Infecções do Sítio Cirúrgico (ISC), compreendendo de 14% a 16% das encontradas em pacientes hospitalizados, são classificadas em incisional superficial, incisional profunda ou de órgão/cavidade. Entre 12% e 84% dessas infecções são detectadas depois que o paciente deixa o hospital, daí a importância da realização da vigilância pós-alta hospitalar. OBJETIVOS: Implementar um serviço de vigilância pós-alta de ISC em mulheres que realizaram cirurgia ginecológica em um Hospital de Ensino em Teresina-PI; monitorizar a ocorrência de ISC e sua associação com fatores de risco; caracterizar o perfil sociodemográfico desse contingente; determinar a taxa de incidência de ISC no ambulatório de ginecologia por meio da vigilância; e identificar o perfil das ISC diagnosticadas após a alta hospitalar. MÉTODO: Estudo quantitativo e prospectivo, realizado no ambulatório de ginecologia do Hospital Getúlio Vargas, o qual é de ensino público, geral, de grande porte e de referência em saúde para o Estado do Piauí e demais regiões do Norte e Nordeste do Brasil. A população foi de 1.026 mulheres egressas do hospital de ensino, que realizaram cirurgia ginecológica, no período de junho de 2011 a março de 2013. O projeto foi aprovado pelo Comitê de Ética e Pesquisa da UFPI, sob o CAAE: 0059. 045. 000.11. RESULTADOS: Utilizou-se a vigilância epidemiológica às ISC do tipo busca ativa, por 30 dias, no ambulatório de ginecologia, por meio de contato presencial e telefônico. A taxa de retorno das mulheres para o ambulatório foi de 86,6% e a incidência de ISC foi de 5,8%, destas, 71,7% foram classificadas como incisional superficial e 28,3% como incisional profunda. O tempo médio entre a cirurgia e o diagnóstico de ISC foi de 12,9 dias; a maior incidência se encontra na faixa etária de 25 a 44 anos (44,3%) de idade; procediam da capital 57,8% e, do interior do Estado, 42,2%; 63% são casadas, 61% tinham até o ensino fundamental; economicamente, 46,4% declararam renda familiar de 1 (um) salário mínimo. Os fatores de risco para o desenvolvimento de ISC foram: Tempo PO (dias), Neoplasia e Diabetes mellitus. CONCLUSÃO: Evidenciou-se o incremento da notificação de incidência de ISC, o que aponta para a importância do acompanhamento das mulheres sob vigilância pós-alta, utilizando uma estratégia sistematizada. Palavras chaves: Vigilância epidemiológica, Procedimentos Cirúrgicos em Ginecologia, Infecção de ferida operatória / Abstract: INTRODUCTION: The Surgical Site Infection (SSI) understanding 14% to 16% of those found in intern patients, and be assorted in superficial incisional SSI, deep incisional SSI, or organ or space SSI. Between 12% and 84% those infections are detected after the patient leaves hospital, hence the importance of post-discharge surveillance. OBJECTIVES: The post-discharge surveillance woman service implementation who underwent gynecological surgery in school hospital in Teresina - PI; monitor the occurrence of ISC and association with risk factors; characterizing the socio-demographic profile; appoint incidence rate (SSI) in gynecological ambulatory for surveillance method, and identify the profile of SSI misdiagnosed after discharge. METHODS: Prospective and quantitative study, accomplished in gynecological ambulatory in Getulio Vargas Hospital, which is for public education, and a large general hospital, and the health reference for the state of Piauí and further the North and Northeast regions of Brazil. The population was 1026 patient women which has undergone gynecological surgery in period from june 2011 to march 2013. The project was approved for the UFPI Research Ethics Committee, under the CAAE: 0059 045 000.11. RESULTS: It was used SSI epidemiologic surveillance, type active report for 30 days in gynecological ambulatory, by face or telephonic contact. Return rate of women to gynecological ambulatory was 86,6% and SSI incidence was 5,8%, those 71,1% was classed in superficial incisional and 28,3% deep incisional. The average time betwixt surgery and SSI diagnosis was 12,9 days; the highest incidence is in the age group 25-44 years (44.3%); came from the city (57,8%) e countryside of the State (42,2%), 63% married women, had basic education 61%, 46,4% declare having minimum wage. The risk factors to SSI development was: OP Time (days), neoplasm and Diabetes mellitus. CONCLUSION: Highlighted the increased incidence of SSI notification, pointing to the importance of accompanying the women in post-discharge surveillance, using a systematic strategy. Key words: Epidemiological surveillance, Gynecologic Surgical Procedures, Surgical wound infection / Mestrado / Ciencias Biomedicas / Doutora em Ciências Médicas

Class of 2012 Abstract / Specific Aims: This study was performed to assess the accuracy of the presenting signs and symptoms, diagnostic procedures, and treatments depicted in episodes one through twelve of the fifth season of House, MD. Methods: This study was a descriptive, retrospective evaluation of the accuracy of the first twelve episodes of the fifth season of House, MD. Dependent variables in this study were presenting signs and symptoms, diagnostic procedures, and treatment of the final diagnosis for the primary patient case. A rating of one to four was assigned to each variable, with one being most accurate and four being inaccurate. Statistical analysis consisted of ANOVA and Tukey HSD post-hoc test Main Results: The signs and symptoms had a mean of 2.42 ± 0.669 (95% CI 1.99 to 2.84). The diagnostic tests had a mean of 2.42 ± 1.084 (95% CI 1.73 to 3.11). The treatment had a mean of 1.42 ± 0.9 (95% CI 0.84 to 1.99). ANOVA showed a statistically significant difference among the accuracy ratings of the groups (p = 0.013). Tukey HSD did not show a significant difference between the accuracy of the signs and symptoms and diagnostic tests (p = 1). The test did reveal a statistically significant difference between accuracy of treatment and both the signs and symptoms (p = 0.027) and diagnostic tests (p = 0.027). Conclusions: The treatments shown in House, MD, season five, episodes one through twelve are significantly more accurate than both the diagnostic tests and the presenting signs and symptoms.

In Analysis and Numerik differential-algebraischer Gleichungen P. Kunkel and V. Mehrmann give a survey of relevant conditions for consistent systems, for existence and uniqueness of solutions, and touch numerical procedures for obtaining the solutions.

The purpose of this study was to evaluate the use of auditory feedback for teaching individuals with intellectual disabilities the “Mississippi Cha Cha Slide.” Participants consisted of six males ages 35 to 61. During baseline, line dance skills were low for all participants. During the auditory feedback intervention, the trainer used a clicker to reinforce dance steps and forward chaining to chain movements into a sequence. Once auditory feedback was implemented, line dance skills increased substantially for all participants. Generalization assessments for four of the participants resulted in performance levels similar to baseline and demonstrate the need for future training with music. Follow up data collected for all four participants showed that dance skills were maintained.

I det här arbetet undersöks det ifall ett CMS som befinner sig på webben kan få bättre exekveringstid ifall databaskod ifrån webbapplikationen istället flyttas till databasen i form av stored procedures. Det har skapats 4 stycken testapplikationer för att testa procedurernas effektivitet jämfört med hur det fungerar originellt. Testapplikationerna skickar en slumpad text till Wordpress funktionerna som har hand om inmatningar till databasen. Textsträngarna matas då in i databasen via antingen procedurer eller databaskod i webbapplikationen beroende på vilken version av Wordpress det är.   I det här arbetet förklaras varför det kan vara intressant att använda sig av stored procedures och vilka för och nackdelar det finns med dem. Resultatet av det här arbetet tyder på att det kan finnas anledningar till att använda sig av procedurer vid större projekt men kan anses som överflödigt vid mindre arbeten.

Class of 2011 Abstract / OBJECTIVES: To evaluate the degree of accuracy of the information relevant to signs and symptoms, diagnostic procedures used to establish the final diagnosis, and appropriateness of treatment for the last 12 episodes of the 3rd season of the television show, House, MD. METHODS: Twelve episodes were reviewed by three evaluators and the patient’s signs and symptoms, the diagnostic procedures used, and the treatment of the final diagnosis for each episode were recorded and rated based on accuracy. After each evaluator had rated each variable in each episode independently, the ratings were compared and a final rating for each variable was determined. RESULTS: The overall mean rating for signs and symptoms was 2.46. The overall mean rating for diagnostic procedures was 2.38. The overall mean rating for treatment was 1.77. All of these ratings would correlate to a correct, but somewhat unusual presentation. The ANOVA analysis found no statistically significant difference between groups (p=0.078). CONCLUSION: The signs and symptoms, diagnostic procedures, and treatments in the episodes of the second half of season three of House, MD were all portrayed in a manner that was accurate, but with a somewhat unusual presentation.

Class of 2011 Abstract / OBJECTIVES: The purpose of this study is to assess the accuracy of the presentation, diagnostic procedures, and treatment of the main disease in each of the first twelve episodes of the third season of the medical drama House, MD. METHODS: The study is a descriptive retrospective evaluation of the first twelve episodes of season three of the medical drama House, MD. The accuracy of the clinical presentation, diagnostic procedures, and treatment in each episode was rated on a scale of one to four. A rating of one described a correct and usual representation. A rating of two described a correct but somewhat unusual representation. A rating of three described a correct but extremely unusual representation. A rating of four described an incorrect representation. Each of three researchers independently rated the episodes, and then the researchers agreed upon a collaborative rating for each category. RESULTS: Results of the ANOVA test did not show statistical significance between the three dependent variables (p = 0.25). Additionally, a Tukey HSD post-hoc test did not reveal a statistical significant difference between the ratings for the presentation, diagnosis, and treatment. CONCLUSION: In the first twelve episodes of season three of House, MD, there was no difference between the accuracy of the treatment and diagnosis when compared to the signs and symptoms of each episode.

Class of 2012 Abstract / Specific Aims: To assess the accuracy of the presenting signs and symptoms, diagnostic procedures, and treatments presented in the last twelve episodes of season five of the popular medical drama, House, MD. Methods: A descriptive retrospective evaluation of the accuracy and inaccuracies of episodes 13 to 24 in season five of the television series House, MD. The accuracy of the presenting signs and symptoms, diagnostic procedures, and treatment in each episode was rated on a scale of one to four. A rating of one described a correct and usual representation. A rating of two described a correct but somewhat unusual representation. A rating of three described a correct but extremely unusual representation. A rating of four described an incorrect representation. Each researcher independently rated the episodes, and then a collaborative rating was agreed upon by both researchers. Main Results: Results of the ANOVA test demonstrated a statistically significant difference between the three dependent variables (p=0.002). The Tukey HSD post-hoc test confirmed a significant difference between the accuracy of treatment when compared with signs and symptoms (p=0.012), and with diagnostic procedures (p=0.002). The average rating for the treatment variable was 1.58 (±0.9), whereas the average ratings for the signs and symptoms and diagnosis variables were 2.75 (± 0.754), and 3 (±1.128), respectively. Conclusions: The treatments presented in the last twelve episode of season five of House, MD were more accurate than both the presenting signs and symptoms and the diagnosis.