The construction of bonds in a controlled and selective manner and the development of operationally simple, general and reliable methods to achieve these aims remains a key goal of chemical synthesis and the countless industries it impacts upon. With this in mind, the chemo-, regio- and stereoselective introduction of a number of functionalities into small molecules was investigated. Traditionally the majority of functionalisations have used precious metals; the scope of transformations that can be achieved using these catalysts is remarkable. Palladium in particular has found widespread application in new bond-forming processes and, in addition to cross-coupling reactions, palladium catalysis has been used to effect a wide variety of asymmetric reactions. This work describes investigations into the palladium-catalysed enantioselective electrophilic fluorination of azaarylacetates and amides A2 and the oxidative annulation of ferrocene derivatives A4 (Scheme A1). Both products have structural significance; heterocycles and stereogenic fluorinated centres, present in A3, are important motifs in the pharmaceutical industry, and ferrocenes are important rigid scaffolds in chiral ligands such as those in the Josiphos family e.g. A7. Scheme A1. Palladium catalysis for a) enantioselective fluorination and b) oxidative annulation Whilst a general catalyst remained elusive for the asymmetric fluorination of azaarylacetates and amides, benzoxazole-containing substrates were consistently fluorinated with excellent enantioselectivity (up to 96% ee) using palladium catalyst A1 (Scheme 1a). The oxidative annulation of ferrocene derivatives proved challenging and although the reaction was successful, the product could only be isolated in up to 24% yield (Scheme 1b). In order to determine the yield-limiting step of the reaction, mechanistic studies were conducted and palladacycle A6 was synthesised as a possible reaction intermediate. Recently there has been a shift towards the development of more sustainable, environmentally benign and economic catalyst systems and iron is quickly becoming recognised as a viable alternative owing to its high natural abundance and low toxicity. A general iron-catalysed hydrofunctionalisation procedure is described that was used to form a wide variety of carbon-carbon and carbon-heteroatom bonds (Scheme A2). Scheme A2. Iron catalysis for carbon-carbon and carbon-heteroatom bond formation With just 0.5 mol% iron catalyst, the broad scope formal hydrofunctionalisation of styrene derivatives was achieved using commercially available and bench-stable catalysts and reagents. An iron-catalysed highly regioselective hydromagnesiation gave a common benzylic Grignard reagent, which was reacted with an array of electrophiles in a highly chemo- and regioselective manner. Significantly, the products of formal hydroboration, hydrosilylation and cross-coupling reactions were obtained.

Types of civil procedure This thesis deals with various kinds of civil procedure. It defines its character, the purpose of its legislation, its principles, parties and their position, rights and responsibilities, and the course of the five kinds of civil proceedings in the Czech republic. In the first chapter there is described the procedure, in which disputes are solved. Courts binding decide concrete disputes and declare, what is right and what is not right. Parties have to declare their rights and proof it. Otherwise they fail the process. In the second part of the first chapter there are defined kinds of civil procedure in which there is no dispute but it is required to regulate this legal relations, for example when somebody dies or lose some legal document. The second chapter deals with proceeding which leads to enforcement, when somebody doesn't voluntarily perform what he have to perform according to the final legal decision. The court or the executor can force this person to perform his obligation. In the third chapter there is described the bankruptcy proceeding and its institutes. The bankruptcy proceeding is regulated in the quite new Bankruptcy act. This chapter deals also with the ways of solution when somebody declare a bankruptcy. The fourth chapter deals with arbitration, in that parties...

Philosophiae Doctor - PhD / Over the past decades, the use and application of statistical concepts for university students have been a big challenge learned from their previous courses. Aftermath of democracy, South African higher education focused on redressing issues of reparation and social imbalances inherited from Apartheid with the commitment to reconstruct a comprehensive educational quality framework. Growing activities lead to new models emphasised to support students and universities in their attempts to demonstrate evidence of enthusiastic statistics learning, with an acceptable degree of accuracy. This study combines quantitative and qualitative research approaches to assess the knowledge of postgraduate students in applying suitable statistical procedures in higher education (HE). The quantitative data were randomly collected from the postgraduate students (n1=307) while the qualitative data were collected through semi-structured interviews (n2=19) from two institutions (University of Cape Town [UCT] and University of the Western Cape [UWC]) in the Western Cape, South Africa. The SPSS V24 statistical package was used for quantitative data analysis and the explorative design was selected as a theoretical framework to guide the investigation, analysis and interpretation of the qualitative findings. UCT model achieved for all combined categories 73% high prediction accuracy. The UWC model revealed similar results, with ask for help, worth of statistics, fear of statistics monitors, affect, cognitive competence, support from significant others, marital status, ethnic groups and type of study as significant predictors with a high prediction accuracy of 75.49%. Additionally, the ethnic groups, marital status, postgraduate programmes, experiences in statistics and effort were significant contributed factors of SELS beliefs while findings of the combined data of UCT and UWC significantly explained the variation observed in SELS beliefs with only 60% model accuracy. Nevertheless, the qualitative data outcomes indicated that the comments of the participants provided a rich understanding of the perceived failure to choose a relevant statistical test. The results further indicated that confusion and frustration characterised the attitude of students during the selection of a suitable statistical test. The original value of this current study is bridging the inequity gap, in terms of statistics learning, and building a substantial input to the achievement of the objectives of UNESCO, the World Education Forum and the White Paper 3, while ultimately, contributing to the sustainable development of learning statistics at universities in the Western Cape, South Africa. By logical extrapolation, this current study proffers significant insights to the rest of the universities in Africa, and beyond.

A dissertation submitted to the Faculty of Dentistry, University of the Witwatersrand, Johannesburg, in part- fulfilment of the requirements for the Degree of Master of Science in Dentistry 1982 / Rat embryos of the post-implantation stage are grown on a static culture medium, for the purpose of assessing growth and development over a 2 day period. The technique used is referred to as the petri-dish culture chamber method. This involves the culture of rat embryos on rat serum, in a controlled environment. Postimplantation embryos from the 6,5 to 8 day stage, and consisting simply of the 3 germ layers, showed a 60% survival rate in. vit/io after 2h hours and A8 hours respectively. After a full A8 hours in vitfio the embryos demonstrated well developed beating hearts, and a neural groove in the process of closing. The survival rate of embryos explanted at later stages was not as successful. The results compare favourably with the results of other workers, using the same method of culture. An advantage of the petri-dish culture chamber is that it allows for easy experimental access to the embryos at all times;a factor to be considered in any technique involving surgical intervention. Although more sophisticated methods have since superseded the static environment petri-dish technique, it is recommended here that this method should not be totally replaced by the more modern circulating culture medium technique. / IT2017

RESUMO O objetivo deste estudo foi avaliar o conhecimento de cirurgiões dentistas inscritos em cursos de estética quanto aos fatores predisponentes e de diagnóstico do câncer bucal, a partir de um questionário previamente testado. O desenvolvimento de materiais e técnicas odontológicas e o anseio cada vez maior do ser humano em busca da beleza têm levado um número crescente de pacientes aos consultórios odontológicos. Julgamos este momento oportuno para informar a população e diagnosticar precocemente o câncer de boca. Com relação às características gerais dos 465 participantes, houve predominância de uma população jovem, com idade inferior a 39 anos, maior participação feminina e quase 1/3 formados de 10 a 20 anos. As características clínicas da ocorrência desta neoplasia não estão claras para os entrevistados, uma vez que somente metade indicou o carcinoma espinocelular como o tipo mais comum, e aproximadamente metade tem conhecimento das características do linfonodo em metástase cervical. Cerca de 20% desconhece a região da boca e a faixa etária de maior ocorrência deste tumor, e também o seu aspecto inicial. Entretanto, 75,7% reconhecem a leucoplasia como a condição mais comumente associada ao câncer bucal. Com relação aos fatores de risco, o consumo de tabaco, história familiar e consumo de álcool estão claros para quase todos os participantes, mas, em se tratando das demais condições apresentadas como fatores de risco, as dúvidas e contradições estão evidentes. Na prática clínica relacionada ao câncer de boca, observa-se que 14,2% não realizam exames para identificar lesões bucais, sendo que, destes, 80,3% não sabem como fazê-lo. Apenas 5,8% realizam procedimentos de diagnóstico, com a grande maioria considerando regular ou insuficiente seu conhecimento na área. Somente 16,6% têm confiança para realizar o diagnóstico. Mais da metade está há mais de 5 anos sem realizar um curso de atualização em câncer de boca, apesar de terem interesse em faze-lo no futuro. Concluindo, os cirurgiões dentistas ainda não apresentam conhecimento e treinamentos ideais para difundir os meios de prevenção e detecção precoce do câncer de boca. / ABSTRACT The purpose of this paper is assessing the knowledge of dentists who are registered at aesthetics courses as for predisposing and diagnosis factors of oral cancer, through a previously tested questionnaire. The development of odontological materials and techniques allied to a longing of a human being who is more and more in search of beauty, has taken an increasing number of patients to odontoligical consultation rooms. We consider this an opportune moment to inform the population and to do the early diagnosis of oral cancer. On what concerns the general characteristics of the 465 participants, there was a predominance of a young population, whose age was under 39 years, more female participation and almost 1/3 who had been graduated for 10 to 20 years. The clinical characteristics of this neoplasia occurrence are not clear for the persons interviewed, since only half of them have indicated the spinocellular carcinoma as the most common one and approximately half of them are aware of the lymph node characteristics in cervical metastasis. Around 20%, ignores the region of the mouth and the age group where this tumor occurs more frequently, and also its initial aspect. Notwithstanding, 75,7% recognizes the leucoplasia as the condition more frequently associated with oral cancer. On what concerns risk factors, the use of tobacco, family history and alcohol intake are clear for almost all the participants, but on what refers to the other conditions presented as risk factors, the doubts and contradictions are evident. On the clinical practice related to oral cancer, it is observed that 14,2% don’t do examinations for identifying buccal lesions, and among these ones, 80,3% don’t know how to do it. Only 5,8% does diagnosis procedures, and the great majority considers their knowledge in the area, regular or insufficient. Only 16,6% has enough confidence to do the diagnosis. In spite of being interested in doing courses in the future, more than half of them have not taken any upgrading course on oral cancer for more than 5 years. Concluding, the dentists still don’t present ideal knowledge and training to diffuse the means for prevention and early detection of mouth cancer.

A qualidade nos serviços de saúde tem sido objeto de estudo entre diversos pesquisadores. As dificuldades econômicas e a exigência dos usuários pelos seus direitos em obter qualidade nos serviços prestados, torna relevante esse estudo. O enfermeiro é o profissional que deve estimular e conduzir a equipe para elaboração e implementação de novas abordagens e ferramentas gerenciais que levem a melhorias na assistência Uma das ferramentas gerenciais que o enfermeiro pode lançar mão é a padronização das intervenções de enfermagem. Devido à necessidade de melhoria da qualidade da assistência prestada, os Procedimentos Operacionais Padrão de enfermagem foram implantados na Secretaria Municipal de Saúde de Ribeirão Preto entre os anos de 2011 e 2012. O estudo objetiva descrever o modelo de implantação dos Procedimentos Operacionais Padrão (POP) da equipe de enfermagem e identificar as fragilidades e potencialidades na utilização desses POP da equipe de enfermagem. Trata-se de pesquisa do tipo avaliativa, com abordagem quantitativa realizada com profissionais de enfermagem que atuam nas Unidades de Saúde da Secretaria Municipal de Saúde de Ribeirão Preto. A coleta de dados foi realizada em duas fases. Na primeira, ocorreu a análise documental que foi realizada no mês de outubro de 2014. Já a segunda fase compreendeu a aplicação de um questionário aos enfermeiros, técnicos e auxiliares de enfermagem. Participaram do estudo 247 profissionais de enfermagem, sendo 64 enfermeiros, 31 técnicos de enfermagem e 152 auxiliares de enfermagem. Destes, 87,4% eram do sexo feminino. A faixa etária que predominou foi a de 51 a 60 anos, com 34%, seguidos de 30,8% na faixa etária de 41 a 50 anos. Em relação ao tempo de formação 38,5% possuíam de 2 a 8 anos de formados, 24,3% possuía de 16 a 22 anos e 19,4% possuíam 23 a 29 anos de tempo de formação. Dos participantes do estudo, 77,7 % atuavam em Unidades de Saúde da Família. Participaram da capacitação dos POP 222 (89,9%) profissionais de enfermagem. Dentre os participantes da pesquisa, 225 (91,1%) afirmaram que consultam os POP no local de trabalho, porém, apenas 142 (57,5%) os consultaram nos últimos doze meses, sendo a maioria enfermeiros (92,2%). A intervenção mais citada que passou a ser executada após a capacitação dos POP foi o cateterismo por cistostomia (17,8%), apesar de ainda haver um percentual de 39,3% que não a executam. Houve mudança na forma de execução e aprofundamento do conhecimento em todas as intervenções trabalhadas. A implantação dos POP foi desenvolvida de forma pontual, necessitando ser avaliado e repensado nos moldes de um processo educativo contínuo. As fragilidades identificadas foram o número reduzido de profissionais, inadequação da estrutura física, ausência de materiais, entre outros. As potencialidades foram relacionadas à padronização dos materiais, material da instituição para consulta disponível na unidade, valorização profissional, preocupação do gestor em relação à segurança do paciente e do profissional. Ressalta-se a capacitação dos POP como relevante para a contribuição da melhoria da qualidade da assistência prestada pela enfermagem, porém, deve ser pautada em processos educativos permanentes / The quality of health services has been the object of study among many researchers. The economic difficulties and demands from users for their rights to obtain quality in the services rendered make this study relevant. Nurses are the professionals who must encourage and lead the team to create and implement new managerial tools and approaches to improve care. One of the managerial tools that nurses can use is the standardization of nursing interventions. Given the need to improve the quality of the care delivered, standard operational procedures(SOP) in nursing were implemented in the Municipal Health Secretariat of RibeirãoPretobetween 2011 and 2012. The aim of this study was to describe the implementation model of the standard operational proceduresof the nursing team and to identify the weak and strong points in the use of these SOP by the nursing team. This was an evaluative study, with a quantitative approach, conducted with nursing professionals who work in health units of the Municipal Health Secretariat of RibeirãoPreto.Data were collected in two phases. The first phase consisted of a documentary analysis performed in October 2014, whereas the second phase comprised the application of a questionnaire to nurses and nursing technicians and aides. The study participants were 247 nursing professionals, namely 64 nurses, 31 nursing technicians and 152 nursing aides. Of these, 87.4% were women. The age range that prevailed was between 51 and 60 years, with 34%, followed by the age range between 41 and 50 years, with 30.8%. Regarding the time since graduation, 38.5% had graduated from 2 to 8 years ago, 24.3% had graduated between 16 and 22 years agoand 19.4% had from 23 to 29 years since graduation. Among the study participants, 77.7% worked in family health units. A total of 222 (89.9%) nursing professionals participated in the training for SOP. Of all study participants, 225 (91.1%) stated refer to SOP at their work place, however, only 142 (57.5%) referred to them over the last 12 months, with most of them being nurses (92.2%). The most commonly cited intervention that started being executed after the SOP training was cystostomy (17.8%), although there is still a percentage of 39.3% professionals who do not perform it. There was a change in the form of execution and broadening of knowledge in all interventions used. The implementation of the SOP was developedfor a specific scenario, so it should be evaluated and replanned in the scope of a continuous educational process. The weak points identified were the reduced number of professionals, inadequate physical structure, lack of materials, among others. The strengths were related to the standardization of materials, institution materials for reference available in the unit, professional appreciation, andconcern on the part of administrators toward the safety of patients and professionals. It is noteworthy that the training for SOP is relevant as it contributes to improve the quality of the nursing care provided, however, it should be guided by permanent educational processes

El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado. / Objective The objective of this study was to investigate the effect of preoperative diastolic dysfunction on postoperative mortality and morbidity after cardiovascular surgery. Methods We systematically searched for articles that assessed the prognostic role of diastolic dysfunction on cardiovascular surgery in PubMed, Cochrane Library, Web of Science, Embase and Scopus until February 2016. Twelve studies (n=8224) met our inclusion criteria. Due to scarcity of outcome events, fixed-effects meta-analysis was performed using the Mantel-Haenszel method. Results Preoperative diagnosis of diastolic dysfunction was associated with higher postoperative mortality (OR 2.41, 95% CI 1.54-3.71; p<0.0001), major adverse cardiac events (MACE) (OR 2.07, 95% CI 1.55-2.78; p <=0.0001) and prolonged mechanical ventilation (OR 2.08, 95% CI 1.04-4.16; p=0.04) in comparison to patients without diastolic dysfunction among patients who underwent cardiovascular surgery. The odds of postoperative myocardial infarction (OR: 1.29, 95% CI 0.82, 2.05; p=0.28) and atrial fibrillation (OR: 2.67; 95% CI 0.49-14.43; p=0.25) did not significantly differ between the two groups. Severity of preoperative diastolic dysfunction was associated with increased postoperative mortality (OR 21.22, 95% CI 3.74 -120.33; p=0.0006) for Grade 3 diastolic dysfunction compared with patients with normal diastolic function. Inclusion of left ventricular ejection fraction (LVEF) <40% accompanying diastolic dysfunction, did not further impact postoperative mortality (p=0.27; I2 =18%) when compared with patients with normal LVEF and diastolic dysfunction. Conclusions Presence of preoperative diastolic dysfunction was associated with higher postoperative mortality and MACE, regardless of LVEF. Mortality was significantly higher in grade III diastolic dysfunction. Keywords Diastolic dysfunction; cardiovascular surgical procedures; mortality; meta-analysis / Revisión por pares

Vinte e nove pacientes submetidos ao Transplante de Medula Óssea Alogênico foram analisados num estudo dirigido às transfusões de hemocomponentes, desde o período pré-transplante até o momento da alta hospitalar, que na maioria das vezes coincidiu com a independência às transfusões. Não houve um padrão único de requerimento transfusional e os fatores que determinaram este fato foram múltiplos. O tipo de doença de base, intercorrências clínicas e a presença da Doença do Enxerto Versus o Hospedeiro estiveram relacionados. As técnicas laboratoriais empregadas na rotina de avaliação dos pacientes ofereceram subsídio adequado, para em conjunto com o exame clínico, proporcionarem parâmetros decisivos na indicação das transfusões sangüíneas. Alguns pacientes apresentaram incompatibilidade ao sistema de grupo sangüíneo ABO com os seus respectivos doadores de medula, fato que não impediu a realização do transplante, devido ao emprego de métodos que permitiram superar esta dificuldade. Foi observada refratariedade às transfusões de concentrados de plaquetas em poucos pacientes da casuística, atribuída à presença de anticorpos contra antígenos do sistema de histocompatibilidade leucocitária humana (HLA). As transfusões de plaquetas obtidas de doadores com o sistema HLA compatível, membros familiares, foram eficazes nestes casos. O tempo de recuperação da função hematopoética da medula transplantada foi similar ao descrito na literatura. / 29 patients who underwent Allogeneic Bone Marrow Transplantation (Allo BMT) were analyzed regarding the need for transfusion of blood components from admission the date of discharge. Most of the time the discharge coincided with blood components transfusion independence. There was no specific pattern of blood products transfusion among these patients. The need for transfusion could be ascribed to the presence of several factors like baseline disease, clinical complications and graf versus host disease. Routine clinical parameters and laboratory techiniques were adequate to indicate the need for transfusion of blood components. Some of the patients were ABO incompatible with their respective marrow donors. We observed no adverse consequence for the outocome of these BMT procedures after the use of routine techiniques to overcome this incompatibility. Few patients were refractory to platelet transfusions that was ascribed to HLA directed antibodies. The use of HLA compatible platelet donors (family members) provided adequate platelet support in these cases. The time to hematopoietic recovery was compatible to the found in the international literature.

Yang Qin. / "June 2003." / Thesis (Ph.D.)--Chinese University of Hong Kong, 2003. / Includes bibliographical references (p. 168-207). / Electronic reproduction. Hong Kong : Chinese University of Hong Kong, [2012] System requirements: Adobe Acrobat Reader. Available via World Wide Web. / Mode of access: World Wide Web. / Abstracts in English and Chinese.

A qualidade nos serviços de saúde tem sido objeto de estudo entre diversos pesquisadores. As dificuldades econômicas e a exigência dos usuários pelos seus direitos em obter qualidade nos serviços prestados, torna relevante esse estudo. O enfermeiro é o profissional que deve estimular e conduzir a equipe para elaboração e implementação de novas abordagens e ferramentas gerenciais que levem a melhorias na assistência Uma das ferramentas gerenciais que o enfermeiro pode lançar mão é a padronização das intervenções de enfermagem. Devido à necessidade de melhoria da qualidade da assistência prestada, os Procedimentos Operacionais Padrão de enfermagem foram implantados na Secretaria Municipal de Saúde de Ribeirão Preto entre os anos de 2011 e 2012. O estudo objetiva descrever o modelo de implantação dos Procedimentos Operacionais Padrão (POP) da equipe de enfermagem e identificar as fragilidades e potencialidades na utilização desses POP da equipe de enfermagem. Trata-se de pesquisa do tipo avaliativa, com abordagem quantitativa realizada com profissionais de enfermagem que atuam nas Unidades de Saúde da Secretaria Municipal de Saúde de Ribeirão Preto. A coleta de dados foi realizada em duas fases. Na primeira, ocorreu a análise documental que foi realizada no mês de outubro de 2014. Já a segunda fase compreendeu a aplicação de um questionário aos enfermeiros, técnicos e auxiliares de enfermagem. Participaram do estudo 247 profissionais de enfermagem, sendo 64 enfermeiros, 31 técnicos de enfermagem e 152 auxiliares de enfermagem. Destes, 87,4% eram do sexo feminino. A faixa etária que predominou foi a de 51 a 60 anos, com 34%, seguidos de 30,8% na faixa etária de 41 a 50 anos. Em relação ao tempo de formação 38,5% possuíam de 2 a 8 anos de formados, 24,3% possuía de 16 a 22 anos e 19,4% possuíam 23 a 29 anos de tempo de formação. Dos participantes do estudo, 77,7 % atuavam em Unidades de Saúde da Família. Participaram da capacitação dos POP 222 (89,9%) profissionais de enfermagem. Dentre os participantes da pesquisa, 225 (91,1%) afirmaram que consultam os POP no local de trabalho, porém, apenas 142 (57,5%) os consultaram nos últimos doze meses, sendo a maioria enfermeiros (92,2%). A intervenção mais citada que passou a ser executada após a capacitação dos POP foi o cateterismo por cistostomia (17,8%), apesar de ainda haver um percentual de 39,3% que não a executam. Houve mudança na forma de execução e aprofundamento do conhecimento em todas as intervenções trabalhadas. A implantação dos POP foi desenvolvida de forma pontual, necessitando ser avaliado e repensado nos moldes de um processo educativo contínuo. As fragilidades identificadas foram o número reduzido de profissionais, inadequação da estrutura física, ausência de materiais, entre outros. As potencialidades foram relacionadas à padronização dos materiais, material da instituição para consulta disponível na unidade, valorização profissional, preocupação do gestor em relação à segurança do paciente e do profissional. Ressalta-se a capacitação dos POP como relevante para a contribuição da melhoria da qualidade da assistência prestada pela enfermagem, porém, deve ser pautada em processos educativos permanentes / The quality of health services has been the object of study among many researchers. The economic difficulties and demands from users for their rights to obtain quality in the services rendered make this study relevant. Nurses are the professionals who must encourage and lead the team to create and implement new managerial tools and approaches to improve care. One of the managerial tools that nurses can use is the standardization of nursing interventions. Given the need to improve the quality of the care delivered, standard operational procedures(SOP) in nursing were implemented in the Municipal Health Secretariat of RibeirãoPretobetween 2011 and 2012. The aim of this study was to describe the implementation model of the standard operational proceduresof the nursing team and to identify the weak and strong points in the use of these SOP by the nursing team. This was an evaluative study, with a quantitative approach, conducted with nursing professionals who work in health units of the Municipal Health Secretariat of RibeirãoPreto.Data were collected in two phases. The first phase consisted of a documentary analysis performed in October 2014, whereas the second phase comprised the application of a questionnaire to nurses and nursing technicians and aides. The study participants were 247 nursing professionals, namely 64 nurses, 31 nursing technicians and 152 nursing aides. Of these, 87.4% were women. The age range that prevailed was between 51 and 60 years, with 34%, followed by the age range between 41 and 50 years, with 30.8%. Regarding the time since graduation, 38.5% had graduated from 2 to 8 years ago, 24.3% had graduated between 16 and 22 years agoand 19.4% had from 23 to 29 years since graduation. Among the study participants, 77.7% worked in family health units. A total of 222 (89.9%) nursing professionals participated in the training for SOP. Of all study participants, 225 (91.1%) stated refer to SOP at their work place, however, only 142 (57.5%) referred to them over the last 12 months, with most of them being nurses (92.2%). The most commonly cited intervention that started being executed after the SOP training was cystostomy (17.8%), although there is still a percentage of 39.3% professionals who do not perform it. There was a change in the form of execution and broadening of knowledge in all interventions used. The implementation of the SOP was developedfor a specific scenario, so it should be evaluated and replanned in the scope of a continuous educational process. The weak points identified were the reduced number of professionals, inadequate physical structure, lack of materials, among others. The strengths were related to the standardization of materials, institution materials for reference available in the unit, professional appreciation, andconcern on the part of administrators toward the safety of patients and professionals. It is noteworthy that the training for SOP is relevant as it contributes to improve the quality of the nursing care provided, however, it should be guided by permanent educational processes