The current cardiac computed tomography (CT) technology is mainly limited by motion blurring and radiation dose. The conceptual multi-source interior CT scheme has provided a potential solution to reduce motion artifacts and radiation exposure. This dissertation work conducted multi-facet investigations on a novel multi-source interior CT architecture (G. Cao, et. al, IEEE Access, 2014;2:1263-71) which employs distributed stationary multi-beam Carbon-nanotube (CNT) X-ray sources and simultaneously operates multiple source-detector chains to improve temporal resolution. The collimation based interior CT is integrated in each imaging chain, to suppress radiation dose. The central thesis statement is: Compared to conventional CT design, this distributed source array based multi-source interior CT architecture shall provide ultra-fast CT scan of region-of-interest (ROI) inside body with comparable image quality at lower radiation dose. Comprehensive studies were conducted to separately investigate three critical aspects of multi-source interior CT: interior CT mode, X-ray scattering, and scatter correction methods. First, a single CNT X-ray source based interior micro-CT was constructed to serve as a down-scaled experimental verification platform for interior CT mode. Interior CT mode demonstrated comparable contrast-noise-ratio (CNR) and image structural similarity to the standard global CT mode, while inducing a significant radiation dose reduction (< 83.9%). Second, the data acquisition of multi-source interior CT was demonstrated at clinical geometry, via numerical simulation and physical experiments. The simultaneously operated source-detector chains induced significant X-ray forward / cross scattering and thus caused severe CNR reduction (< 68.5%) and CT number error (< 1122 HU). To address the scatter artifacts, a stationary beam-stopper-array (BSA) based and a source-trigger-sequence (STS) based scatter correction methods were proposed to enable the online scatter measurement / correction with further radiation dose reduction (< 50%). Moreover, a deterministic physics model was also developed to iteratively remove the scatter-artifacts in the multi-source interior CT, without the need for modifications in imaging hardware or protocols. The three proposed scatter correction methods improved CNR (< 94.0%) and suppressed CT number error (< 48 HU). With the dedicated scatter correction methods, the multi-source interior CT could provide ROI-oriented imaging with acceptable image quality at significantly reduced radiation dose. / Ph. D. / Cardiac computed tomography (CT) technology enables a non-invasive imaging examination of patients’ cardiovascular system, and thus it has been widely applied in the fields of the diagnosis, treatment, and scientific research of cardiovascular diseases (CVD). The image quality of the current cardiac CT is frequently degraded by rapid cardiac motion and X-ray scattering, and the potential radiation harm has also raised public concern. The above limitations could be theoretically overcome by a recently proposed conceptual stationary multi-beam X-ray sources based interior CT (i.e. multi-source interior CT) system architecture. This dissertation conducted a comprehensive investigation on the actual image quality and radiation dose of this conceptual CT system. The experiments demonstrated that a significant radiation dose reduction could be achieved in multi-source interior CT. The image quality of multi-source interior CT could be maintained with the in-housedeveloped scatter correction methods.

The domestic and geopolitical disaster of the Vietnam War, and the process that took the United States into such a large-scale and protracted conflict, led Congress to reinforce its checks on executive war powers. The resulting War Powers Resolution (WPR) sought to inject Congress back into the decision-making process, yet no President has ever acknowledged its constitutionality. The initial debates around the WPR revealed four major lines of argument on the balance of war powers; three of those continued to be made over the next 40 years, as Presidents from both political parties deployed U.S. forces abroad, often without Congressional authorization. This study analyzed the prevalence and distribution of those lines of argument in the U.S. Senate over the Republican Administration of President George W. Bush and the Democratic Administration of President Barack Obama. Both administrations were involved in multiple deployments of U.S. forces abroad, and experienced opposition from both parties. The study found that Democrats displayed consistency across both administrations, indicating a preference for institutional loyalty in supporting compliance with the WPR, whereas Republicans tended to support the status quo. In addition, the study found that Senators from both parties acknowledged the rapidly changing nature of warfare as new technologies mostly remove U.S. armed forces from harm's way even as they conduct lethal strikes. What effect this has on Congress's ability and willingness to further check executive war powers remains to be seen, but it is clear that the debate is far from over. / Master of Arts / The Vietnam War led Congress to reinforce its checks on executive war powers. The resulting War Powers Resolution (WPR) sought to inject Congress back into the decision-making process. The initial debates around the WPR revealed four major lines of argument on the balance of war powers; three of those continued to be made over the next 40 years. This study looked at those three lines of argument in the U.S. Senate over the Republican Administration of President George W. Bush and the Democratic Administration of President Barack Obama. The study found that Democrats consistently took a position that defended the powers of the Congress, whereas Republicans tended to support a status quo that deferred to the power of the President. In addition, the study found that Senators from both parties acknowledged the rapidly changing nature of warfare. What effect this has on Congress’s ability and willingness to further check executive war powers remains to be seen, but it is clear that the debate is far from over.

No / A macrocycle, 6, has been synthesized in high yield from 2,5-di(pyrazol-1-yl)hydroquinone and 1,1`-fc[B(Me)NMe2]2 {fc = Fe(C5H4)2}. The molecule incorporates two redox-active 1,1`-ferrocenylene units in its backbone and contains four chiral boron centers, each of them possessing the same configuration. It is demonstrated that crystal structures of organometallics of moderate complexity can be solved from high-resolution X-ray powder diffraction patterns, once the connectivity between the functional groups is known.

Analog-to-digital converters (ADCs) are used to convert analog signals to the digital domain in digital communications systems. An ADC used in wireless communications should meet the necessary requirements for the worst-case channel condition. However, the worst-case scenario rarely occurs. As a consequence, a high-resolution and subsequently high power ADC designed for the worst case is not required for most operating conditions. A solution to reduce the power dissipation of ADCs in wireless digital communications systems is to detect the current channel condition and to dynamically vary the resolution of the ADC according to the given channel condition. In this thesis, we investigated an ADC that can change its resolution dynamically and, consequently, its power dissipation. Our ADC is a switched-current, redundant signed-digit (RSD) cyclic implementation that easily incorporates variable resolution. Furthermore, the RSD cyclic algorithm is insensitive to offsets, allowing simple, low-power comparators. Our ADC is implemented in a 0.35 um CMOS technology with a single-ended 3.3 V power supply. Our ADC has a maximum power dissipation of 6.35 mW for a 12-bit resolution and dissipates an average of 10 percent less power when the resolution is decreased by two bits. Simulation results indicate our ADC achieves a bit rate of 1.7 MHz and has a SNR of 84 dB for the maximum input frequency of 8.3 kHz. / Master of Science

Yes / This paper demonstrates the practical application of process mapping principles as a model for evaluating NHS improvement. The NHS improvement in question was the merger of three crisis resolution teams within an NHS trust in 2012. The aims were to improve overall operational efficiency and enhance multidisciplinary working to meet operational targets. This paper examined changes following the merger to capture the effects of service improvement and the reality of the patient journey. Methods: A pooled cross-sectional approach, using six years of aggregated hospital data, was taken. To achieve operational efficiency, a process map of referrals, readmissions, length of stay and waiting times for crisis resolution team assessments was examined. Prevalence of clinical referral rates and disease classification before and after the merger were compared. Conclusion: Between 1 April 2009 and 30 March 2015, length of stay and readmissions for patients to crisis resolution team rates reduced. Operational sustainability and capacity was enhanced through the redistribution of clinical human resources. Multidisciplinary skill mix (e.g. through improved team composition) also improved.

It is hoped that this paper can establish by such documentary evidence as is available, the following: 1. The program for financing social security advocated by W. Lee O'Daniel during his first term as Governor of Texas; 2. The program for old age assistance advocated by O'Daniel during the Forty-Sixth Legislature of Texas; 3. The activities of the minority group credited by the Governor with defeating "all efforts to finance social security" during the Forty-Sixth Legislature; 4. The explanation of Senate Joint Resolution 12; 5. The record, based on personal experience and the reported evidence, of the various groups and individuals working for the passage of Senate Joint Resolution 12.

The objective of this study was to locate and describe the learning affordances used within research studies on instructional design. Allowing an instructional designer to see what was used and how applicable it might be for future design would assist with better course creation. Current and past literature supported the importance of this concept after examination of how course creation has evolved within the field of instructional design. Further, the findings elucidated how to help the field evolve in the future by expanding knowledge about learning affordances and providing the broadest set of conceptual definitions by the academics working in the field to include them in their research and instructional designs.

Light microscopy is inherently limited in resolution by properties of light such as diffraction and interference to 170-250 nm. Expansion microscopy is a quickly-developing method which achieves super-resolution by using a swellable hydrogel to physically expand biological samples themselves, rather than depending on the properties of fluorophores. This thesis demonstrates that expansion microscopy is a feasible means for achieving super-resolution in transmitted light microscopy modes. Though it has only been used for fluorescence imaging in the past, here I show that samples prepared for expansion microscopy—including liver tissue slices and myofibrillar bundles—are observable using transmitted light. While the majority of the original sample material is removed in the expansion process, the hydrogel retains visible evidence of these samples. These demonstrate increased detail under brightfield microscopy that is useful for characterization. Sarcomeric regions are identifiable by this method and are confirmed by fluorescence imaging. Thus, expansion microscopy is a means to bring super-resolution to transmitted light imaging and is entirely compatible with fluorescence for the localization of proteins of interest.

Thesis (LLD)--Stellenbosch University, 2012. / Includes bibliography / ENGLISH ABSTRACT: South African law does not recognise an inherent right to the existing, unobstructed view from a property. Nevertheless, seemingly in disregard of this general principle, property owners often attempt to protect such views and courts sometimes in fact grant orders that provide such protection. This dissertation aims to establish whether South African law does indeed not acknowledge a right to a view and whether there are any exceptions to the general rule against the recognition of the right to a view. The principle that the existing view from a property is not an inherent property right is rooted in Roman and Roman-Dutch law. This principle was received in early South African case law. Inconsistency in the application of the principle in recent case law renders its development uncertain. An analysis of recent decisions shows that the view from a property is sometimes protected in terms of servitudes or similar devices, or by virtue of legislation. In other instances, property owners attempt to prevent the erection of a neighbouring building that will interfere with their existing views, based either on a substantive right or an administrative shortcoming. When the protection of view is based on a limited real right (servitudes or similar devices) or legislation, it is generally effective and permanent. Conversely, when it is founded on a substantive right to prevent building on neighbouring land or an administrative irregularity rendering a neighbouring building objectionable, the protection is indirect and temporary. A comparative study confirms that the position regarding the protection of view is similar in English and Dutch law. Constitutional analysis in terms of the methodology developed by the Constitutional Court in FNB indicates that cases where view is protected are not in conflict with section 25(1) of the Constitution of the Republic of South Africa, 1996. The investigation concludes with an evaluation of policy considerations which show that the position with regard to a right to a view in South African law is rooted in legitimate policy rationales. / AFRIKAANSE OPSOMMING: 'n Inherente reg op die bestaande, onbelemmerde uitsig vanaf 'n eiendom word nie deur die Suid-Afrikaanse reg erken nie. Desnieteenstaande poog eienaars dikwels om die uitsig vanaf hul eiendomme te beskerm en soms staan die howe bevele tot dien effekte toe. Dit skep die indruk dat die Suid-Afrikaanse reg wel die bestaande uitsig vanaf 'n eiendom as 'n inherente eiendomsreg erken of dat sodanige uitsig minstens onder sekere omstandighede beskerm kan word. Hierdie verhandeling het ten doel om onsekerhede betreffende die algemene beginsel oor 'n reg op uitsig uit die weg te ruim en om lig te werp op gevalle waar 'n onbelemmerde uitsig wel beskerm word. Die Romeinse en Romeins-Hollandse reg het nie 'n reg op uitsig erken nie. Hierdie posisie is deur vroeë regspraak in die Suid-Afrikaanse regstelsel opgeneem. 'n Ondersoek na latere Suid-Afrikaanse regspraak toon egter aan dat howe wel onder sekere omstandighede, skynbaar strydig met die gemeenregtelike beginsel, beskerming aan die onbelemmerde uitsig vanaf eiendomme verleen. 'n Eerste kategorie sake behels gevalle waar die uitsig vanaf 'n eiendom deur 'n beperkte saaklike reg, in die vorm van 'n serwituut of 'n soortgelyke maatreël, of ingevolge wetgewing beskerm word. In 'n tweede kategorie sake word die beskerming van 'n uitsig deur middel van 'n aanval op die goedkeuring van 'n buureienaar se bouplanne bewerkstellig. Sodanige aanval kan óf op 'n substantiewe reg óf op 'n administratiewe tekortkoming berus. Die onderskeie kategorieë verskil wat betref die doelmatigheid en omvang van die beskerming wat verleen word. 'n Saaklike reg of wetgewing verleen meestal effektiewe en permanente beskerming. Hierteenoor het 'n aanval op die goedkeuring van 'n buureienaar se bouplanne hoogstens indirekte en tydelike beskerming van die uitsig tot gevolg. Regsvergelyking bevestig dat die Engelse en Nederlandse reg die Suid-Afrikaanse posisie ten opsigte van'n reg op uitsig tot 'n groot mate eggo. Grondwetlike analise aan die hand van die FNB-metodologie dui daarop dat die gevalle waar uitsig wel beskerming geniet nie strydig is met artikel 25(1) van die Grondwet van die Republiek van Suid-Afrika, 1996 nie. Bowendien regverdig beleidsgronde die behoud van die huidige beginsel in die Suid-Afrikaanse reg.

Pulse (fluid) pressure modulator was constructed for comprehensive gas chromatography. Optimal conditions of its connection to the gas chromatograph with a flame ionization detector were found for the analysis of selected mixture of volatile solvents. Pressure interdependences in the system and relations between dimensions of modulator capillaries and columns have been evaluated with respect to the length of the modulation period and pulse duration. Two non-polar columns (15 m × 0.25 mm DB-5MS, 10 m × 0.15 mm CP-Sil 5 CB) of the same stationary phase were tested to compare the separation efficiency in the first dimension and the DB-5MS column was selected. The Supelcowax 10 columns of the lengths 1, 2 and 3 m were compared in the second dimension. It was found that using of 3 m length column lead to the extension of analysis time, however the increase in separation efficiency in the second dimension was very evident. The experimental measurements have shown that the selected parameters for the evaluation of the separation efficiency (the peak capacity and total resolution product) were inappropriate. Gasoline, kerosene and diesel fuel were analyzed as examples of real samples. Amount of added ethanol as a biofuel additive was determined in the gasoline sample. Pulse pressure modulator was modified...