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The Global ETD Search service is a free service for researchers
to find electronic theses and dissertations. This service is
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Networked Digital Library of Theses and Dissertations.
Our metadata is collected from universities around the world. If you manage a university/consortium/country archive and want to be added, details can be found on the NDLTD website.
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Showing 101 to 102 of 102 (0.009 seconds)| 101 |
Modelagem dinâmica de separador bifásico com alimentação por escoamento em regime de golfadas / Dynamic modeling of two-phase separator with feeding for draining in regimen of slugRosilene Abreu Portella 07 August 2008 (has links)
Petróleo Brasileiro S.A. / O presente trabalho aborda o comportamento da planta de processamento primário com alimentação por fluxo em padrão de golfadas. O fluxo no sistema de tubulações é descrito por um
modelo de parâmetros concentrados, fornecendo as características principais necessárias para o controle da planta, e a resposta dinâmica desta pode então ser analisada. Usando a estratégia de controle tradicional verifica-se que as oscilações de fluxo são transmitidas para as vazões de saída de líquido e gás, para obter uma vazão de saída mais estável é permitida a flutuação de carga no separador dentro de uma tolerância, isto é possível reduzindo a atuação do controlador e estabelecendo um controle adicional diretamente na válvula de entrada. / The present work addresses the behavior of a primary processing plant subjected to slug flow pattern at its entrance. The flow in a pipeline system is described by a simplified concentrated
parameter model, which preserves the main physical features that are important to control the plant. The dynamic response of the plant is then analyzed. Using a standard control strategy for
the gas liquid separator, it is seen that the flow oscillations are transmitted to the liquid and gas outlets. In order to obtain a more stable outlet flow, the liquid level in the separator is then
allowed to fluctuate within a given range, by reducing the effect of the controller constants, and establishing an additional control directly on the inlet entrance valve.
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Mecanismes de regulació en l'activitat biològica del factor de transcripció SnailDomínguez Solà, David 03 April 2003 (has links)
Els factors de transcripció de la família Snail són fonamentals en la "transició epiteli-mesènquima", procés morfogènic essencial en el desenvolupament embrionari i en els fenòmens metastàsics tumorals.En els mamífers l'activitat d'Snail és modulada per dos mecanismes. (i) En el promotor humà es troben regions definides de resposta a factors repressors, predominants en les cèl·lules epitelials, i elements diferenciats de resposta a inductors de la "transició epiteli-mesènquima". (ii) L'activitat d'Snail és condicionada també per la seva localització subcel·lular, modulada per mecanismes no transcripcionals: la fosforilació d'Snail determina si és o no exclós del nucli. Al citosol no pot actuar com a repressor transcripcional però pot interaccionar amb la xarxa microtubular, que estabilitza i en condiciona el dinamisme. Això coincideix amb l'activació de la GTPasa RhoA i la reorientació dels filaments de vimentina, fets associats a l'adquisició de capacitat migratòria. L'efecte com a repressor transcripcional i la modulació del dinamisme microtubular són possiblement esdeveniments coordinats necessaris per al rol biològic d'Snail en mamífers. / Snail family of transcription factors is fundamental to the "epithelial-mesenchymal transition", morphogenic process essential to embryonic development and metastatic phenomena in tumors.Snail's activity is modulated in two ways in mammals. (i) The human promoter harbors definite regions that respond to repressor factors, which prevail in epithelial cells; and differentiated elements that respond to known inducers of the "epithelial-mesenchymal transition". (ii) Snail's activity is also conditioned by its subcellular localization, mechanism not dependent on its transcriptional control: Snail phosphorylation determines whether Snail is excluded or not from the nucleus. When in the cytosol, Snail is unable to act as a transcriptional repressor, but however binds to the microtubular meshwork, which becomes stabilized and whose dynamism is conditioned as a result. This fact coincides with the activation of the RhoA GTPase and reorientation of vimentin filaments, both phenomena being related to the acquisition of cell motility. The transcriptional repressor and the microtubule dynamics effects are probably two coordinated events necessary to Snail's biological role in mammals.
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