Global ETD Search

1	Untersuchungen zum dTDP-L-Mycarose-Biosyntheseweg des Erythromycin-A-Produzenten Saccharopolyspora erythraea NRRL 2338 Weingarten, Petra. January 2000 (has links) (PDF) Wuppertal, Universiẗat, Diss., 2000. Saccharopolyspora erythraea
2	Expression, Reinigung und Charakterisierung von Makrolid-Glykosyltransferasen für die Synthese neuartiger Makrolid-Antibiotika Schumacher, Thomas. Unknown Date (has links) (PDF) Techn. Hochsch., Diss., 2005--Aachen.
3	Purification, functional characterization and crystallization of the PerR peroxide sensor from Saccharopolyspora erythraea Elison Kalman, Grim January 2019 (has links) This report summarizes the work on the cloning, expression, and purification of PerR, a metal sensing regulator from Saccharopolyspora erythraea and the subsequent characterization using small angle X-ray scattering and other biochemical methods. The report aims to provide an insight into prokaryotic metal homeostasis, provide a better understanding of how PerR works and provide valuable information for the continued work on the crystallization of PerR. structural biology cell culture protein expression genetic engineering spectroscopy X-ray crystallography small angle X-ray scattering SAXS transcription factor PerR metal binding antibiotics Saccharopolyspora erythraea S. erythraea soil bacterium actinobacteria actinomycetes oxidative stress peroxide stress structure determination characterization stabilization peroxide sensor iron sensor manganese sensor metalloprotein metal ion homeostasis metal ion prokaryotic strukturbiologi cellodling proteinuttryck genteknik spektroskopi röntgenkristallografi småvinkel-röntgenspridning SAXS transkriptionsfaktor PerR metallbindande antibiotika Saccharopolyspora erythraea S. erythraea jordartsbakterie Aktinobakterier Actinobacteria Actinomycetes oxidativ stress peroxid stress strukturbestämning karaktärisering stabilisering peroxidsensor järnsensor mangansensor metalljonshomeostas metalljoner prokaryot Structural Biology Strukturbiologi
4	In vitro polyketide biocatalysis : triketide building-blocks and enzymology Harper, Andrew David 08 October 2013 (has links) Polyketide products are useful compounds to research and industry but can be difficult to access due to their richness in stereogenic centers. Type I polyketide synthases offer unique engineering opportunities to access natural stereocontrol and resultant complex compounds. The development of a controlled in vitro platform based around type I polyketide synthases is described. It has been used to produce a small library of polyketide fragments on an unprecedented and synthetically-relevant scale and explore polyketide synthase enzymology. / text In vitro Cell-free Preparative Polyketide Polyketide synthase Ketoreductase Malonyl-CoA ligase MatB Enzymology Chiral building blocks Chiral synthons Diketide Triketide Lactone Ketolactone Natural products Secondary metabolism Secondary metabolite Modular Type I polyketide synthase Biosynthesis Streptomyces coelicolor Saccharopolyspora erythraea Bacillus subtilis Streptomyces nodosus Saccharomyces cerevisiae Streptomyces antibioticus Streptomyces venezuelae Saccharopolyspora spinosa Streptomyces fradiae

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