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71	A Multi-physics Framework for Wearable Microneedle-based Therapeutic Platforms: From Sensing to a Closed-Loop Diabetes Management. Marco Fratus (19193188) 22 July 2024 (has links) <p dir="ltr">Ultra-scaled, always-on, smart, wearable and implantable (WI) therapeutic platforms define the research frontier of modern personalized medicine. The WI platform integrates real-time sensing with on-demand therapy and is ideally suited for real-time management of chronic diseases like diabetes. Traditional blood tracking methods, such as glucometers, are insufficient due to their once-in-a-while measurements and the imprecision of insulin injections, which can lead to severe complications. To address these challenges, researchers have been developing smart and minimally invasive microneedle (MN) components for pain-free glucose detection and drug delivery, potentially functioning as an "artificial pancreas". Inspired by natural body homeostasis, these platforms must be accurate and responsive for immediate corrective interventions. However, artificial MN patches often have slow readings due to factors like MN morphology and composition that remain poorly understood, hindering their optimization and integration into real-time monitoring devices. Despite extensive, iterative experimental efforts worldwide, a holistic framework incorporating the interaction between MN sensing and therapy with fluctuating natural body functions is missing. In this thesis, we propose a generalized framework for glycemic management based on the interaction between biological processes and MN-based operations. The results, incorporating theoretical insights from the 1960s and recent advancements in MN technology, are platform-agnostic. This generality offers a unique template to interpret experimental observations, justify the recent introduction of drugs like GLP-1 cocktails, and optimize platforms for accurate and fast disease management. </p> Medical devices Electronic sensors Micro- and nanosystems Biosensing Applications Development Sensors and actuators microneedle sensor patch drug delivery model closed-loop configuration glucose-insulin feedback loop Feedback Loop Controls response time limit electrochemical response properties universal scaling relations
72	TELEMETRY IN THEATER MISSILE DEFENSE DEVELOPMENT Toole, Michael T. 10 1900 (has links) International Telemetering Conference Proceedings / October 17-20, 1994 / Town & Country Hotel and Conference Center, San Diego, California / Since the Gulf War, there has been significant interest in Theater Missile Defense (TMD) resulting in funding growth from tens of millions of dollars at the time of the Gulf War to $1.7 Billion in 1994. The Ballistic Missile Defense Organization (BMDO) has developed a Theater Missile Defense test and evaluation program that will assess technological feasibility and the degree to which system functionality and performance meet technical and operational requirements. The complexity of the TMD program necessitates a comprehensive test program which includes flight testing, ground testing, and modeling and simulation. This article will provide and overview the requirements and capabilities needed to satisfy these requirements. The data processing, and telemetry communities will play a major role in providing the expertise to support the development of the nation’s future Theater Missile Defense capabilities. Theater Missile Defense test and evaluation system performance live flight testing ground testing modeling and simulation Air Defense CINCs experiments optical measurement X-band measurement phenomenology data collection THAAD interceptor radar BMC3 System Integration Test ERINT missile Sealite Beam Director High Energy Laser National Test Facility Airborne Surveillance Testbed HALO Rapid Optical Beam Sensing system Cobra Eye Cobra Judy Aria P3 GPS WSMR TSPI Kwajalein distributed interactive simulation
73	Enhancing Creative, Learning and Collaborative Experiences through Augmented Reality-compatible Internet-of-Things Devices Pashin Farsak Raja (15348238) 29 April 2023 (has links) <p>The "Maker Movement" is a cultural phenomena rooted in DIY culture, which stresses making devices and creations on your own rather than purchasing it ready-made. At the core of the Maker Movement, is the "Maker Mindset"; a collection of attitudes, beliefs and behaviors that emphasize the importance of creativity, experimentation and innovation in the learning process. Since the Maker Mindset embodies constructionist principles at its core that push makers to experiment and problem-solve by collaborating with fellow makers through hands-on activities, it can be said that these activities comprise of Creative, Learning and Collaborative experiences. While Internet-of-Things devices have long been used to enhance these activities, research pertaining to using Augmented Reality in tandem with IoT for the purpose of enhancing experiences core to the Maker Mindset is relatively unexplored. Three different systems were developed with the goal of addressing this -- MicrokARts, ShARed IoT and MechARspace. Each system focuses on enhancing one of the three core experiences through AR-compatible IoT devices, whilst ensuring that they do not require prerequisite knowledge in order to author AR experiences. These systems were evaluated through user studies and testing over a variety of age-groups, with each system successfully enhancing one core experience each through the use of AR-IoT interactions.</p> Analog electronics and interfaces Human-computer interaction Maker Movement IoT Internet-of-Things Maker Community Maker Mindset Augmented Reality Mechanical Engineering Human-Computer Interaction Computer-Human Interaction Electronics Simulation Creativity Collaboration Learning

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