The aim of this paper is to understand how trans people who write and read fanfiction about gender euphoria create meaningful writing processes, contextualize community, and orientate themselves in the world by telling stories about gender euphoria and related emotional experiences. I have conducted interactive chat interviews with four study participants and have, as a way of using an autoethnographic research method, included my own narratives as part of the material. Thus, the material used in this study consists of transcripts of collective sensemaking and discussions about differences and similarities in the experiences that the study participants and I tell each other about. I have analyzed the material using queer phenomenology and affect theory. I have found that the study participants have both varied and similar experiences of finding representation, of translating their emotions into actions, and of (re)shaping what it is that they, as trans people, can do and what narratives they can tell and experience.

This theoretical thesis is focused on mapping and comparing the leading psychological transpersonal approaches to the conception of development of consciousness of an individual. This research is exploring the theory of Ken Wilber, Michael Washburn and Stanislav Grof also paying attention to the main disagreement among them regarding the confusion of prepersonal and transpersonal spheres of consciousness. This disagreement is further elaborated in an effort to find a conclusion and to seek for an integrative theory. The theories are compared with regard to the findings about psychedelic experience. The psychedelic experience is psychologically elaborated with emphasis on the current scientific knowledge in the field and their embedding in the context of the developmental theories of consciousness taking the effort of unravelling the pre/trans fallacy and the clinical implications into account. KEYWORDS Developmental theory, consciousness, transpersonal, psychedelics, pre/trans fallacy

Yes / If a prosthetic foot creates resistance to forwards shank rotation as it deforms during loading, it will exert a braking effect on centre of mass progression. The present study determines whether the centre of mass braking effect exerted by an amputee's habitual rigid ‘ankle’ foot was reduced when they switched to using an ‘Echelon’ hydraulic ankle–foot device. Nineteen lower limb amputees (eight trans-femoral, eleven trans-tibial) walked overground using their habitual dynamic-response foot with rigid ‘ankle’ or ‘Echelon’ hydraulic ankle–foot device. Analysis determined changes in how the centre of mass was transferred onto and above the prosthetic-foot, freely chosen walking speed, and spatio-temporal parameters of gait. When using the hydraulic device both groups had a smoother/more rapid progression of the centre of pressure beneath the prosthetic hindfoot (p ≤ 0.001), and a smaller reduction in centre of mass velocity during prosthetic-stance (p < 0.001). As a result freely chosen walking speed was higher in both groups when using the device (p ≤ 0.005). In both groups stance and swing times and cadence were unaffected by foot condition whereas step length tended (p < 0.07) to increase bilaterally when using the hydraulic device. Effect size differences between foot types were comparable across groups. Use of a hydraulic ankle–foot device reduced the foot's braking effect for both amputee groups. Findings suggest that attenuation of the braking effect from the foot in early stance may be more important to prosthetic-foot function than its ability to return energy in late stance.

Thesis advisor: Shih-Yuan Liu / Thesis advisor: Amir H. Hoveyda / Chapter 1. Senphos–Palladium-Catalyzed cis-Carboboration of Internal 1,3-Enynes with Carbon–Bound Boron Enolates: Reaction Development and Mechanistic Analysis. A new family of carbon-bound boron enolates (C–boron enolates) that are created through a kinetically controlled halogen exchange process between B–chlorocatecholborane and silylketene acetals is presented. These C–boron enolates are demonstrated to activate 1,3-enynes substrates in the presence of a Senphos-Pd complex to achieve carboboration reaction of an alkyne unit. This carboboration reaction produced highly substituted dienyl boron building blocks in high site-, regio-, and diastereoselectivity. A combined experimental and computational study of this carboboration reaction by Density-Functional Theory (DFT) calculations, 31P NMR study, kinetic study, Hammett analysis and Arrhenius/Eyring analysis will also be described. Mechanistic study supports a syn outer-sphere oxidative addition mechanism featuring a Pd-π-allyl intermediate followed by coordination-assisted rearrangement instead of the conventional inner-sphere β-migratory insertion mechanism. Chapter 2. trans-Hydroalkynylation of Internal 1,3-Enynes Enabled by Cooperative Catalysis. A trans-hydroalkynylation reaction of internal 1,3-enynes enabled by a cooperative catalysis system that comprises of Senphos–Pd complex, tris(pentafluorophenyl)borane, copper(I) bromide, and 2,2,6,6-tetramethylpiperidine, is described. The tris(pentafluorophenyl)borane as Lewis acid catalyst is shown to promote the reaction involving the emerging outer-sphere oxidative reaction step. This hydroalkynylation reaction affords the cross-conjugated dieneynes that serve as versatile synthons for organic synthesis. The photophysical properties of these cross-conjugated dieneynes depend on the position of electron donor/acceptor substituents along the conjugation path, as characterized by UV–vis absorption and emissions spectroscopy. Chapter 3. Senphos–Palladium/B(C6F5)3-Catalyzed trans-Hydrothiolation of 1,3-Enynes: Reaction Development and Mechanistic Analysis. A trans-hydrothiolation reaction of 1,3-enynes enabled by a cooperative catalysis system that comprises of Senphos–Pd complex and tris(pentafluorophenyl)borane is detailed. The tris(pentafluorophenyl)borane is shown to alter the reaction pathway, leading to a trans-addition product over cis-addition one. Experimental mechanistic study that includes 31P NMR, kinetic study, kinetic isotope effect (KIE) study, Hammett analysis, is consistent with a cooperative activation mechanism that features an outer-sphere protonation step. / Thesis (PhD) — Boston College, 2023. / Submitted to: Boston College. Graduate School of Arts and Sciences. / Discipline: Chemistry.

Under de senaste 10 åren har gruppen som sökt hjälp för könsdysfori ökat. Personer med könsdysfori är särskilt utsatta för att utveckla psykisk ohälsa jämfört med befolkningen i övrigt. Det saknas dock kunskap om deras närståendes upplevelser. Den här studien är del av svenska könsdysforistudien, SKDS. Syftet med studien var att i en svensk kontext undersöka närståendes upplevelse av att leva nära en person som genomgår utredning och behandling för könsdysfori. Utifrån semistrukturerade intervjuer med elva närstående tolkades materialet genom induktiv tematisk analys. Analysen visade att de närstående upplevt att relationen fördjupats genom processen. Oavsett varierande reaktioner initialt har samtliga närstående landat i en vilja att genom fördjupad kunskap stå upp för den vårdsökande. För många har processen känts tung och ensam. Samsjuklighet och minoritetsstress har bidragit till ökad komplexitet och tyngd. Man har också hittat kraft i den gemensamma kampen. En slutsats är att den icke-dömande hållningen och oreserverade acceptansen hos de närstående, inte i samma grad återspeglats i internationella studier. En ytterligare slutsats är att de närstående utgör en viktig resurs i den vårdsökandes möjlighet till ett gynnsamt behandlingsutfall och att de närstående behöver uppmärksammas och erbjudas stöd för att själva kunna vara ett stöd. / Delstudie till Svenska könsdysforistudien (SKDS)

The objective of the study was to examine the effects of trans-9-octadecenoic acid (elaidic) and trans-II-octadecenoic acid (trans-vaccenic) on uptake and alteration of exogenous fatty acids by mouse mammary epithelial cells. Cells from a subclone of the COMMA-D cell line were plated on uncoated plastic petri dishes and grown to confluence. Supplemental fatty acids bound to bovine serum albumin were added to the medium applied to the confluent cell cultures. Treatments included 200 JlM octadecanoic acid (CI8:0) as a control and 100 JlM CI8:0 with one of the following JlM ratios of cis-octadecenoic acid (cis-CI8:I) to elaidic or trans-vaccenic: 100:0, 75:25, 50:50, 0:100. In addition, all treatments were conducted with or without lactogenic hormone supplementation. The cellular protein to DNA ratio and total amount of fatty acids per mg protein were decreased (P < .05) by addition of lactogenic hormones. In treatments without hormone supplementation, however, the total amount of cellular fatty acids per mg protein was decreased (P < .05) by addition of either trans-CI8:I isomer. Results indicated a significant (P < .05) relationship between the concentration oftrans-C18:1 in the media and uptake of trans-C 18: 1 isomers, and retroconversion of trans-C 18: 1 to trans-C 16: 1. The slopes of the lines for cellular C16:0, cis-C16:1, and cis-CI8:1 were less (P < .05) than zero as concentration oftrans-CI8:1 in the media increased. However, trans-CI8:1 isomers did not influence the proportion of polar and nonpolar lipids synthesized by the cells. It appears that trans fatty acids may depress milk fat output by decreasing de novo fatty acid synthesis and cis-C 18: I content. / Master of Science

No description available.

The study goal was to construct and psychometrically validate a negative’s attitudes towards trans people scale (EANT) as an expression of prejudice against trans. Two interdepen- dent sequential studies through questionnaires are reported, both rely on non-probabilistic samples: Study 1, involves 203 participants, mainly college students, addresses the construction and exploratory analysis of the EANT. Study 2, involving 408 participants assigned according to s ociodemographic quotes established by the national census in the general population, shows confirmatory factor analysis and external validation of the scale. A sole factor 9-item instrument, with acceptable internal consistency (α = .886) was obtained. The results suggest good applicability in general population studies. Expected relations with typical variables (ATLG, RWA, SDO and religiosity) were procured. / Se construye y valida psicométricamente una escala de actitudes negativas hacia personas trans (EANT) como expresión del prejuicio hacia las mismas. Se reportan dos estudios secuenciales interdependientes por cuestionarios a partir de muestreos no probabilísticos. El estudio 1, con 203 participantes, en su mayoría estudiantes universitarios, aborda la construcción y análisis exploratorio de la EANT. El estudio 2, con 408 participantes según cuotas sociodemográficas establecidas por el censo nacional en la población general, estudia los análisis factoriales confirmatorios y la validación externa de la escala. Se obtuvo un instrumento unifactorial de 9 ítems, con una consistencia interna aceptable (α = .886) que sugiere una adecuada aplicabilidad en población general, así como relaciones esperables convariables típicas (ATLG, RWA, SDO y religiosidad).

Submitted by Renata Lopes (renatasil82@gmail.com) on 2015-12-04T11:30:17Z No. of bitstreams: 1 marianamacedodealmeida.pdf: 4650594 bytes, checksum: 73217ac8cb6474bd22ccc88955919c7c (MD5) / Approved for entry into archive by Adriana Oliveira (adriana.oliveira@ufjf.edu.br) on 2015-12-07T03:19:20Z (GMT) No. of bitstreams: 1 marianamacedodealmeida.pdf: 4650594 bytes, checksum: 73217ac8cb6474bd22ccc88955919c7c (MD5) / Made available in DSpace on 2015-12-07T03:19:20Z (GMT). No. of bitstreams: 1 marianamacedodealmeida.pdf: 4650594 bytes, checksum: 73217ac8cb6474bd22ccc88955919c7c (MD5) Previous issue date: 2015-03-04 / A prevalência de sobrepeso e obesidade está crescendo em taxa alarmante no mundo. Essas condições fornecem maior risco para doenças crônicas, incluindo diabetes tipo 2. Nesse contexto, o ácido linoléico conjugado (CLA) tem atraído considerável atenção, principalmente devido às suas propriedades antiobesidade e antidiabética. O presente estudo objetivou avaliar de forma independente os efeitos do CLA proveniente de fontes natural e sintética sobre o risco de obesidade, sensibilidade à insulina e perfil de lipídeos séricos. Cinquenta ratos Wistar machos foram atribuídos aos seguintes tratamentos dietéticos (n=10/ grupo), por 60 dias: Controle Normolipídico (CN): dieta contendo 4,0% de óleo de soja (OS); Manteiga Controle (MC): dieta contendo 21,7% de manteiga padrão e 2,3% de OS; Manteiga enriquecida com CLA (M-CLA): dieta contendo 21,7% de manteiga enriquecida com CLA cis-9, trans-11 e 2,3% de OS; Controle Hiperlipídico (CH): dieta contendo 24,0% de OS e CLA Sintético (S-CLA): dieta contendo 1,5% de mistura de isômeros de CLA (Luta-CLA 60) e 22,5% de OS. Os animais alimentados com M-CLA tiveram menores níveis de insulina em jejum do que aqueles alimentados com dieta MC, enquando os níveis de PPARγ no tecido adiposo foram aumentados no grupo M-CLA comparado com o grupo MC. Além disso, R-QUICK foi menor nos animais alimentados com MC do que naqueles alimentados com CN, enquanto nenhuma diferença no R-QUICK foi observada entre os grupos CN e M-CLA. Os níveis de colesterol HDL e triglicérides foram maiores nos ratos alimentados com CLA-M. Portanto, a manteiga alto CLA preveniu a hiperinsulinemia, aumentou o colesterol HDL e causou hipertrigliceridemia. A dieta S-CLA não teve efeito sobre a ingestão alimentar e composição alimentar. Os ratos alimentados com S-CLA apresentaram menores níveis da proteína PPARγ no tecido adiposo, hiperinsulinemia, hiperglicemia, índice de HOMA aumentado e maiores níveis de colesterol HDL. Portanto, cautela deve ser tomada antes que suplemetos sintéticos contendo CLA cis-9, trans-11 e CLA trans- 10, cis-12 sejam recomendados. / The prevalence of overweight and obesity is increasing at an alarming rate. These conditions are a major risk for chronic diseases, including type 2 diabetes. In this context, conjugated linoleic acid (CLA) has attracted considerable attention, mainly due to its anti-obesity and anti-diabetic properties. The present study aimed to independently evaluate the effects of CLA from natural and synthetic sources on obesity risk, insulin sensibility and profile of serum lipids. Fifty male Wistar rats were assigned to the following dietary treatments (n=10/group), for 60 days: Normolipidic Control (CN): diet containing 4.0% soybean oil (SO); Control Butter (MC): diet containing 21.7% standard butter and 2.3% SO; and CLA enriched Butter (M-CLA): diet containing 21.7% cis-9, trans-11 CLA-enriched butter and 2.3% SO; Hyperlipidic Control (CH), diet containing 24.0% SO; Synthetic CLA (S-CLA), diet containing 1.5% of an isomeric CLA mixture (Luta-CLA 60) and 22.5% SO. M-CLA-fed rats had lower serum insulin levels at fasting than those fed with the MC diet, while the PPARγ protein levels in adipose tissue was increased in M-CLA-fed rats compared to MCfed rats. Furthermore, R-QUICK was lower in MC than in CN group, while no differences in R-QUICK were observed among CN and M-CLA. Serum HDL cholesterol and triacylglycerol levels were higher in M-CLA-fed rat. Thus, feeding rats on a high-fat diet containing butter naturally enriched in cis-9, trans-11 CLA prevented hyperinsulinemia, increased HDL cholesterol levels and caused hypertriglyceridemia. The S-CLA diet had no effect on dietary intake and body composition. S-CLA-fed rats had lower levels of PPARγ protein in adipose tissue, hyperinsulinemia, hyperglycemia, increased HOMA index and higher levels of serum HDL cholesterol. Therefore, caution should be taken before synthetic supplements containing cis-9, trans-11 and trans-10, cis-12 CLA are recommended.

No description available.