Performance analysis often considers numerous factors contributing to performance, and the relative importance of these factors is evolving based on dynamic conditions and requirements. Investigating large numbers of factors and understanding individual factors' predictability within the ultimate performance are challenging tasks. A visual analytics approach that integrates interactive analysis, novel visual representations, and predictive machine learning models can provide new capabilities to examine performance effectively and thoroughly. Currently, only limited research has been done on the possible applications of visual analytics for performance evaluation. In this dissertation, two specific types of performance analysis are presented: (1) organizational employee performance evaluation and (2) performance improvement of machine learning models with interactive feature selection. Both application scenarios leverage the human-in-the-loop approach to assist the identification of influential factors. For organizational employee performance evaluation, a novel visual analytics system, MetricsVis, is developed to support exploratory organizational performance analysis. MetricsVis incorporates hybrid evaluation metrics that integrate quantitative measurements of observed employee achievements and subjective feedback on the relative importance of these achievements to demonstrate employee performance at and between multiple levels regarding the organizational hierarchy. MetricsVis II extends the original system by including actual supervisor ratings and user-guided rankings to capture preferences from users through derived weights. Comparing user preferences with objective employee workload data enables users to relate user evaluation to historical observations and even discover potential bias. For interactive feature selection and model evaluation, a visual analytics system, FeatureExplorer, allows users to refine and diagnose a model iteratively by selecting features based on their domain knowledge, interchangeable features, feature importance, and the resulting model performance. FeatureExplorer enables users to identify stable, trustable, and credible predictive features that contribute significantly to a prediction model.

Geodateninfrastrukturen (GDI) erfahren in den letzten Jahren immer weitere Verbreitung durch die Schaffung neuer Standards zum Austausch von Geodaten. Die vom Open Geospatial Consortium (OGC), einem Zusammenschluss aus Forschungseinrichtungen und privaten Firmen, entwickelten offenen Beschreibungen von Dienste-Schnittstellen verbessern die Interoperabilität in GDI. OGC-konforme Geodienste werden momentan hauptsächlich zur Aufnahme, Verwaltung, Prozessierung und Visualisierung von Geodaten verwendet. Durch das vermehrte Aufkommen von Geodiensten steigt die Verfügbarkeit von Geodaten. Gleichzeitig hält der Trend zur Generierung immer größerer Datenmengen beispielsweise durch wissenschaftliche Simulationen an (Unwin et al., 2006). Dieser führt zu einem wachsenden Bedarf an Funktionalität zur effektiven Exploration und Analyse von Geodaten, da komplexe Zusammenhänge in großen Datenbeständen untersucht und relevante Informationen heraus gefiltert werden müssen. Dazu angewendete Techniken werden im Forschungsfeld Visual Analytics (Visuelle Analyse) umfassend beschrieben. Die visuelle Analyse beschäftigt sich mit der Entwicklung von Werkzeugen und Techniken zur automatisierten Analyse und interaktiven Visualisierung zum Verständnis großer und komplexer Datensätze (Keim et al., 2008). Bei aktuellen Web-basierten Anwendungen zur Exploration und Analyse handelt es sich hauptsächlich um Client-Server-Systeme, die auf fest gekoppelten Datenbanken arbeiten. Mit den wachsenden Fähigkeiten von Geodateninfrastrukturen steigt das Interesse, Funktionalitäten zur Datenanalyse in einer GDI anzubieten. Das Zusammenspiel von bekannten Analysetechniken und etablierten Standards zur Verarbeitung von Geodaten kann dem Nutzer die Möglichkeit geben, in einer Webanwendung interaktiv auf ad hoc eingebundenen Geodaten zu arbeiten. Damit lassen sich mittels aktueller Technologien Einsichten in komplexe Daten gewinnen, ihnen zugrunde liegende Zusammenhänge verstehen und Aussagen zur Entscheidungsunterstützung ableiten. In dieser Arbeit wird die Eignung der OGC WMS GetFeatureInfo-Operation zur Analyse raum-zeitlicher Geodaten in einer GDI untersucht. Der Schwerpunkt liegt auf der dynamischen Generierung von Diagrammen unter Nutzung externer Web Map Service (WMS) als Datenquellen. Nach der Besprechung von Grundlagen zur Datenmodellierung und GDIStandards, wird auf relevante Aspekte der Datenanalyse und Visualisierung von Diagrammen eingegangen. Die Aufstellung einer Task Taxonomie dient der Untersuchung, welche raumzeitlichen Analysen sich durch die GetFeatureInfo-Operation umsetzen lassen. Es erfolgt die Konzeption einer Systemarchitektur zur Umsetzung der Datenanalyse auf verteilten Geodaten. Zur Sicherstellung eines konsistenten und OGC-konformen Datenaustauschs zwischen den Systemkomponenenten, wird ein GML-Schema erarbeitet. Anschließend wird durch eine prototypischen Implementierung die Machbarkeit der Diagramm-basierten Analyse auf Klimasimulationsdaten des ECHAM5-Modells verifiziert. / Spatial data infrastructures (SDI) have been subject to a widening dispersion in the last decade, through the development of standards for the exchange of geodata. The open descriptions of service interfaces, developed by the OGC, a consortium from research institutions and private sector companies, alter interoperability in SDI. Until now, OGC-conform geoservices are mainly utilised for the recording, management, processing and visualisation of geodata. Through the ongoing emergence of spatial data services there is a rise in the availability of geodata. At the same time, the trend of the generation of ever increasing amounts of data, e. g. by scientific simulation (Unwin et al., 2006), continues. By this, the need for capabilities to effectively explore and analyse geodata is growing. Complex relations in huge data need to be determined and relevant information extracted. Techniques, which are capable of this, are being described extensively by Visual Analytics. This field of research engages in the development of tools and techniques for automated analysis and interactive visualisation of huge and complex data (Keim et al., 2008). Current web-based applications for the exploration and analysis are usually established as Client-Server approaches, working on a tightly coupled data storage (see subsection 3.3). With the growing capabilities of SDI, there is an increasing interest in offering functionality for data analysis. The combination of widely used analysis techniques and well-established standards for the treatment of geodata may offer the possibility of working interactively on ad hoc integrated data. This will allow insights into large amounts of complex data, understand natural interrelations and derive knowledge for spatial decision support by the use of state-of-the-art technologies. In this paper, the capabilities of the OGC WMS GetFeatureInfo operation for the analysis of spatio-temporal geodata in a SDI are investigated. The main focus is on dynamic generation of diagrams by the use of distributed WMS as a data storage. After the review of basics in data modelling and SDI-standards, relevant aspects of data analysis and visualisation of diagrams are treated. The compilation of a task taxonomy aids in the determination of realisable spatio-temporal analysis tasks by use of the GetFeatureInfo operation. In the following, conceptual design of a multi-layered system architecture to accomplish data analysis on distributed datasets, is carried out. In response to one of the main issues, a GML-schema is developed to ensure consistent and OGC-conform data exchange among the system components. To verify the feasibility of integration of diagram-based analysis in a SDI, a system prototype is developed to explore ECHAM5 climate model data.

The semantic annotation of large multimedia corpora is essential for numerous tasks. Be it for the training of classification algorithms, efficient content retrieval, or for analytical reasoning, appropriate labels are often the first necessity before automatic processing becomes efficient. However, manual labeling of large datasets is time-consuming and tedious. Hence, we present a new visual approach for labeling and retrieval of reports in multimedia news corpora. It combines automatic classifier training based on caption text from news reports with human interpretation to ease the annotation process. In our approach, users can initialize labels with keyword queries and iteratively annotate examples to train a classifier. The proposed visualization displays representative results in an overview that allows to follow different annotation strategies (e.g., active learning) and assess the quality of the classifier. Based on a usage scenario, we demonstrate the successful application of our approach. Therein, users label several topics which interest them and retrieve related documents with high confidence from three years of news reports.

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For many software projects, keeping requirements on track needs an effective and efficient path from data to decision. Visual analytics creates such a path that enables the human to extract insights by interacting with the relevant information. While various requirements visualization techniques exist, few have produced end-to-end values to practitioners. In this dissertation, we advance the literature on visual requirements analytics by characterizing its key components and relationships in a framework. We follow the goal-question-metric paradigm to define the framework by teasing out five conceptual goals (user, data, model, visualization, and knowledge), their specific operationalizations, and their interconnections. The framework allows us to not only assess existing approaches, but also create tool enhancements in a principled manner. We evaluate our enhanced tool supports both qualitatively and quantitatively. First, we evaluate our tool supports qualitatively through a case study where massive, heterogeneous, and dynamic requirements are processed, visualized, and analyzed. Working together with practitioners on a contemporary software project within its real-life context leads to the main ending that visual analytics can help tackle both open-ended visual exploration tasks and well-structured visual exploitation tasks in requirements engineering. In addition, the study helps the practitioners to reach actionable decisions in a wide range of areas relating to their project, ranging from theme and outlier identification, over requirements tracing, to risk assessment. Overall our work illuminates how the data-to-decision analytical capabilities could be improved by the increased interactivity of requirements visualization. Although many new visual analytics tools, techniques and methods are being developed, still there is a lack of understanding of how to evaluate the performance of such tools. We conducted an experiment to assess the performance (time and correctness) of our visual analytics tool support in solving requirements engineering tasks. Our study provides initial evidence and insights for visual analytics in requirements engineering and sheds light on many challenging open questions.

This dissertation introduces FESM (Flood Event Simulation Model), a Geographic Information System (GIS) tool designed for use on gaged river systems that can be used to guide logistic support during disaster events. FESM rapidly generates flood predictions using elevation data from real-world sensors or generated by other models. Verification and validation data for FESM are provided. In order to construct a visualization system for interacting with FESM outputs, single buffer and dual buffer techniques for moving massive datasets to the GPU for processing using OpenCL were rigorously tested and timed, and an analysis of the costs/benefits of using buffers or images was conducted. Finally, DRO (Dynamic Raster Overlay), a visualization system for analysis of datasets composed of multiple overlapping flood maps is introduced, and expert feedback is provided on the effectiveness of DRO with selected case studies.

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Arsenic is a universal environmental toxicant associated mostly with skin related diseases in people exposed to low doses over a long term. Low dose arsenic trioxide (ATO) with long exposure will lead to chronic exposure. Experiments were performed to provide new knowledge on the incompletely understood mechanisms of action of chronic low dose inorganic arsenic in keratinocytes. Cytotoxicity patterns of ATO on long-term cultures of HaCaT cells on collagen IV was studied over a time course of 14 days. DNA damage was also assessed. The percentages of viable cells after exposure were measured on Day 2, Day 5, Day 8, and Day 14. Statistical and visual analytics approaches were used for data analysis. In the result, a biphasic toxicity response was observed at a 5 μg/ml dose with cell viability peaking on Day 8 in both chronic and acute exposures. Furthermore, a low dose of 1 μg/ml ATO enhanced HaCaT keratinocyte proliferation but also caused DNA damage. Global gene expression study using microarray technique demonstrated differential expressions of genes in HaCaT cell exposed to 0.5 μg/ml dose of ATO up to 22 passages. Four of the up-regulated and 1 down-regulated genes were selected and confirmed with qRT-PCR technique. These include; Aldo-Keto Reductase family 1, member C3 (AKR1C3), Insulin Growth Factor-Like family member 1 (IGFL1), Interleukin 1 Receptor, type 2 (IL1R2) and Tumour Necrosis Factor [ligand] Super-Family, member 18 (TNFSF18), and down-regulated Regulator of G-protein Signalling 2 (RGS2). The decline in growth inhibiting gene (RGS2) and increase in AKR1C3 may be the contributory path to chronic inflammation leading to metaplasia. This pathway is proposed to be a mechanism leading to carcinogenesis in skin keratinocytes. The observed over expression of IGFL1 may be a means of triggering carcinogenesis in HaCaT keratinocytes. In conclusion, it was established that at very low doses, arsenic is genotoxic and induces aberrations in gene expression though it may appear to enhance cell proliferation. The expression of two genes encoding membrane proteins IL1R2 and TNFSF18 may serve as possible biomarkers of skin keratinocytes intoxication due to arsenic exposure. This research provides insights into previously unknown gene markers that may explain the mechanisms of arsenic-induced dermal disorders including skin cancer / Environmental Sciences / D. Phil. (Environmental science)