Due to the increasing demands of third-party payers to show measurable results in a decreased amount of time, mental health practitioners need new tools and techniques to quickly and efficiently assess their client's current status and progress in treatment. The goal of this study was to develop and validate a brief computerized measure of emotional states and personality traits for use as an assessment tool in a clinical setting. Adapted from the State-Trait Personality Inventory (STPI; Spielberger, 1998), the computerized instrument measured state and trait anxiety, anger, depression, and curiosity. The computerized STPI was examined for equivalence with the traditional STPI and compared with therapists' ratings of their clients' emotional states and personality traits. Forty individuals (24 women, 16 men) in psychotherapy were administered either a computerized version of the STPI or the original, paper version. Each client's therapist was asked to rate him or her on the same 4 states and 4 traits measured by the STPI. In addition, clients and therapists answered short questionnaires regarding their reactions to the STPI and the client report generated by the STPI, respectively. A comparison of mean STPI scale scores between the computerized and paper administration groups showed slightly higher levels of reported state emotion for the computerized administration. There was no other evidence of differences between the two experimental groups. Therapists who had previously conducted assessment with their client demonstrated a significantly higher correlation of their ratings with the corresponding client STPI self-reported scores. Feedback from the client and therapist exit questionnaires suggested that their reactions to the procedure and the usefulness of the STPI were quite favorable. Implications of increasing the use of computers in clinical assessment are discussed.

Cyber insider threat is one of the most difficult risks to mitigate in organizations. However, innovative validated visualizations for cyber analysts to better decipher and react to detected anomalies has not been reported in literature or in industry. Attacks caused by malicious insiders can cause millions of dollars in losses to an organization. Though there have been advances in Intrusion Detection Systems (IDSs) over the last three decades, traditional IDSs do not specialize in anomaly identification caused by insiders. There is also a profuse amount of data being presented to cyber analysts when deciphering big data and reacting to data breach incidents using complex information systems. Information visualization is pertinent to the identification and mitigation of malicious cyber insider threats. The main goal of this study was to develop and validate, using Subject Matter Experts (SME), an executive insider threat dashboard visualization prototype. Using the developed prototype, an experimental study was conducted, which aimed to assess the perceived effectiveness in enhancing the analysts’ interface when complex data correlations are presented to mitigate malicious insiders cyber threats. Dashboard-based visualization techniques could be used to give full visibility of network progress and problems in real-time, especially within complex and stressful environments. For instance, in an Emergency Room (ER), there are four main vital signs used for urgent patient triage. Cybersecurity vital signs can give cyber analysts clear focal points during high severity issues. Pilots must expeditiously reference the Heads Up Display (HUD), which presents only key indicators to make critical decisions during unwarranted deviations or an immediate threat. Current dashboard-based visualization techniques have yet to be fully validated within the field of cybersecurity. This study developed a visualization prototype based on SME input utilizing the Delphi method. SMEs validated the perceived effectiveness of several different types of the developed visualization dashboard. Quantitative analysis of SME’s perceived effectiveness via self-reported value and satisfaction data as well as qualitative analysis of feedback provided during the experiments using the prototype developed were performed. This study identified critical cyber visualization variables and identified visualization techniques. The identifications were then used to develop QUICK.v™ a prototype to be used when mitigating potentially malicious cyber insider threats. The perceived effectiveness of QUICK.v™ was then validated. Insights from this study can aid organizations in enhancing cybersecurity dashboard visualizations by depicting only critical cybersecurity vital signs.

Introduction: Research show that patients frequently display abnormal vital signs as much as 48h before a serious adverse event occur, such as cardiac arrest or unplanned intensive care unit admission. Therefore, early recognition of these changes trough vital sign examination is essential in the prevention of deterioration. However, deterioration is often missed.Aim: The aim was to investigate to what extent nurses in the general ward are documenting vital signs prior to patient deterioration. Methods: A systematic literature review was done usingthe databases PubMed and CINAHL. Inclusion criteria: general ward and publication 2010-2020, exclusion criteria:emergency department, acute admission ward, paediatric ward, psychiatric ward, interventions and continuousmonitoring. Critical appraisalusingtools from Joanna Briggs Institute. PRISMA statement for reporting of systematic reviews.Results: Nine studies were included. It was seen that the fraction of cases who had vital signs documented prior to deterioration was diverse, although never complete. Some studies showed an acceptable fraction of patients who weremonitoredin the hours prior to deterioration, but it was seen that the monitoring did not always escalate as the patient got worse. The vital signs most frequently documentedwereheart rate and pulse, thoughstill missing in a large fraction of charts. Respiratory rate was documented less than the other vital signs.Conclusions: This study suggests that documentation of vital signs prior to deterioration is diverse but often incomplete. Further research is needed to understand what can be done to improve vital sign documentation on general wards.

Bedömning av patientens vitalparametrar (andningsfrekvens, blodtryck, puls, kroppstemperatur, saturation och medvetandegrad) är sjuksköterskans ansvar inom den akuta vårdkedjan. Tidigare forskning visar att en tidig identifiering av försämrade patienter minskar både mortalitet och morbiditet. För patientens välmående och säkerhet är det av högsta vikt att sjuksköterskor utför evidensbaserade och säkra bedömningar för att upprätthålla patientsäkerheten. Syftet var att utforska faktorer som påverkar sjuksköterskans bedömning av vitalparametrar för att tidigt upptäcka en försämrad patient inom den intrahospitala akuta vårdkedjan.  En litteraturöversikt med systematisk artikelsökning användes som metod. Databassökningar utfördes i PubMed och CINAHL. Sexton originalartiklar som undersökte sjuksköterskors bedömning av patientens vitalparametrar i den akuta vårdkedjan valdes ut från databassökningen samt manuell sökning. Studierna kvalitetsgranskades för att sedan analyseras med hjälp av integrerad analys.  Resultatet visade att sjuksköterskors bedömning av vitalparametrar påverkades av sjuksköterskefaktorer, patientfaktorer samt organisatoriska faktorer. Sjuksköterskefaktorer som sågs påverka var sjuksköterskans förhållningssätt till vitalparametrar, bedömning av frekvens, kunskap och erfarenhet, intuition, helhetsbild samt avsteg från rutiner. Gällande patientfaktorer sågs specifika patientgrupper svårare att bedöma på grund av exempelvis underliggande grundsjukdomar eller ålder. Organisatoriska faktorer som sågs påverka bedömningen var arbetsmiljö, samarbete/kommunikation, kontinuitet i vården samt bedömningsinstrument.   Slutsats som dras är att sjuksköterskans bedömning av vitalparametrar för att tidigt upptäcka en försämrad patient inom den akuta vårdkedjan är ett komplext ämne som påverkas av både sjuksköterske-, patient-, och organisatoriska faktorer. Även då vitalparametrar är ett viktigt redskap för att upptäcka förändring i patientens tillstånd och således främja patientens välmående och säkerhet, använder inte sjuksköterskans alltid dessa verktyg. Denna studie gav inte några säkra förklaringar till varför detta fenomen förekom utan behöver studeras vidare. / Assessing the patient's vital signs (respiratory rate, blood pressure, pulse, body temperature, saturation, and level of consciousness) is a responsibility assigned to the registered nurse within the emergency care chain. Previous research has shown that early identification of deteriorating patients reduces both mortality and morbidity. To enhance patient safety and well-being, it is vital that the registered nurse performs evidence-based and secure assessments of the patient.  The aim of this study was to explore the factors that influence the nurse’s assessments of vital signs to early detect patient deterioration within emergency care.   The research method used was a literature review with a systematic approach, using database searches in PubMed and CINAHL. Sixteen original articles with the main focus of examining registered nurses’ assessments of vital signs within emergency care was chosen from the database searches and manual searches. The quality of the studies was then examined, and an integrated analysis was performed.  The result of the analysis show that assessment of vital signs performed by registered nurses was affected by factors contributed to the nurse, the patient, and the organization as a whole.  When it comes to the factors found contributed to affect the registered nurses, these factors were found to be, approach to vital signs, assessment of frequency, knowledge and experience, intuition, comprehensive picture, and deviations from the established routine. For the factors contributed by the patient, specific patient groups were regarded as more difficult to assess due to underlying diseases or age.  The organisational factors seen affecting the nursing assessment were the work environment, teamwork/communication, continuity in the care and the evaluation tools at hand.  In conclusion, the results show that this is a complex subject that is affected by several factors contributed to the registered nurse, patient, and the organization. Even though vital signs are an important tool to identify changes in a patient’s well-being and safety, the registered nurse does not always utilize this as a tool. This study could not conclude any clear explanation as to why assessing vital signs was not used more often and will require further studies and analysis to determine an answer.

WebAssembly is a new binary code specification, which was initially designed to complement JavaScript in web applications. WebAssembly is inherently portable and small, designed for multiplatform usage. Therefore, WebAssembly modules can be created to support embedded system-based biomedical sensor operation. However, WebAssembly has its own limitations to compensate with its portability. In this thesis, we show how WebAssembly modules can be applied to the basic biomedical modalities of body temperature, heart rate, and breathing pattern.  We show how the implementation performed, and what challenges were met during the development. It is concluded that WebAssembly can be applied for achieving safe and effective biomedical sensor devices, although with some limitations. / WebAssembly är ett nytt binärt maskinkodsformat, ursprungligen skapat för att komplettera JavaScript i webbapplikationer.  WebAssemblys kod är liten och kan lätt användas på flera plattformar. Därför kan WebAssembly-moduler skapas för att stödja inbyggda system för biomedicinska sensorer. WebAssembly har dock sina egna begränsningar på grund av sin portabilitet.  I denna avhandling visar vi hur WebAssembly-moduler kan användas på enkla biomedicinska mätningar av kroppstemperatur, hjärtfrekvens och andningsmönster. Vi visar hur implementeringen genomfördes och vilka utmaningar som möttes under utvecklingen. Slutsatsen är att WebAssembly kan tillämpas för att skapa säkra och effektiva biomedicinska sensorenheter, även om det finns en del begränsningar.

The use of ultra-wideband (UWB) signals holds great promise for remote monitoring of vital-signs which has applications in the medical, for first responder and in security. Previous research has shown the feasibility of a UWB-based radar system for respiratory and heartbeat rate estimation. Some simulation and real experimental results are presented to demonstrate the capability of the respiration rate detection. However, past analysis are mostly based upon the assumption of an ideal experiment environment. The accuracy of the estimation and interference factors of this technology has not been investigated. This thesis establishes an analytical framework for the FFT-based signal processing algorithms to detect periodic bio-signals from a single target. Based on both simulation and experimental data, three basic challenges are identified: (1) Small body movement during the measurement interval results in slow variations in the consecutive received waveforms which mask the signals of interest. (2) The relatively strong respiratory signal with its harmonics greatly impact the detection of heartbeat rate. (3) The non-stationary nature of bio-signals creates challenges for spectral analysis. Having identified these problems, adaptive signal processing techniques have been developed which effectively mitigate these problems. Specifically, an ellipse-fitting algorithm is adopted to track and compensate the aperiodic large-scale body motion, and a wavelet-based filter is applied for attenuating the interference caused by respiratory harmonics to accurately estimate the heartbeat frequency. Additionally, the spectrum estimation of non-stationary signals is examined using a different transform method. Results from simulation and experiments show that substantial improvement is obtained by the use of these techniques. Further, this thesis examines the possibility of multi-target detection based on the same measurement setup. Array processing techniques with subspace-based algorithms are applied to estimate multiple respiration rates from different targets. The combination of array processing and single- target detection techniques are developed to extract the heartbeat rates. The performance is examined via simulation and experimental results and the limitation of the current measurement setup is discussed. / Master of Science

Yes / Routine administrative data have been used to show that patients admitted to hospitals over the weekend appear to have a higher mortality compared to weekday admissions. Such data do not take the severity of sickness of a patient on admission into account. Our aim was to incorporate a standardized vital signs physiological-based measure of sickness known as the National Early Warning Score to investigate if weekend admissions are: sicker as measured by their index National Early Warning Score; have an increased mortality; and experience longer delays in the recording of their index National Early Warning Score. Methods: We extracted details of all adult emergency medical admissions during 2014 from hospital databases and linked these with electronic National Early Warning Score data in four acute hospitals. We analysed 47,117 emergency admissions after excluding 1657 records, where National Early Warning Score was missing or the first (index) National Early Warning Score was recorded outside ±24 h of the admission time. Results: Emergency medical admissions at the weekend had higher index National Early Warning Score (weekend: 2.53 vs. weekday: 2.30, p

Abstract The aim of the studie was to investigate if the Pediatric Early Warning Score system, PEWS, is an useful instrument on a children's inpatient ward, regarding the detecting of deterioration in children's vital signs. For this, a quantitative descriptive design with qualitative elements was used. Method: Study specific questionnaires were distributed to 86 persons (helpnurses, nurses and doctors). Of these, 36 answered and sent back the surveys. Results: Of 36 responses 25 felt experienced a faster detection of deterioration of vital signs in the child. Many felt that they had faster response from the physician on call by providing an assessment figure of the child's condition. Conclusion: Most of the persons experienced that the use of the assessment intrument PEWS detected a deterioration of the child´s vital signs earlier than before using the instrument. Staff experienced greater security in their work when they had a tool to help and they also experienced an earlier response from physicians. / SAMMANFATTNING   Syftet med studien var att undersöka om bedömningsinstrumentet Pediatric Early Warning Score, PEWS, är till användning och vägledning på barnavdelning med avseende att upptäcka försämring av barns vitalparametrar. För detta användes en beskrivande kvantitativ design med kvalitativa inslag. Metod: Ett studiespecifikt enkätformulär gick ut till 86 personer (undersköterskor, sjuksköterskor och läkare på två pediatriska vårdavdelningar). Av dessa besvarades 36 enkäter. Resultat: Av 36 svarande ansåg 25 att man snabbare upptäckte försämring av vitalparametrarna hos barnet. Många ansåg att de fick snabbare gensvar från jourläkare genom att uppge en bedömningssiffra över barnets hälsotillstånd. Slutsats: Med hjälp av bedömningsinstrumentet PEWS upplevde personalen att en upptäckt av försämring av barnets vitalparametrar gjordes tidigare, samt att gensvar från jourläkare erhölls snabbare. Personalen upplevde en ökad trygghet i sitt arbete då man hade ett arbetsredskap till hjälp.

Submitted by VAGNER CAVALCANTI DE ALBUQUERQUE null (vcaru@hotmail.com) on 2017-04-17T01:57:15Z No. of bitstreams: 1 DISSERTAÇÃO EDIÇÃO FINAL pós-defesa.pdf: 1227730 bytes, checksum: e3844dcb989e38a6f0f401ccffa890e0 (MD5) / Approved for entry into archive by Luiz Galeffi (luizgaleffi@gmail.com) on 2017-04-18T17:53:45Z (GMT) No. of bitstreams: 1 albuquerque_vc_me_bot.pdf: 1227730 bytes, checksum: e3844dcb989e38a6f0f401ccffa890e0 (MD5) / Made available in DSpace on 2017-04-18T17:53:45Z (GMT). No. of bitstreams: 1 albuquerque_vc_me_bot.pdf: 1227730 bytes, checksum: e3844dcb989e38a6f0f401ccffa890e0 (MD5) Previous issue date: 2017-02-20 / Introdução: A triagem e avaliação inicial de pacientes com hipovolemia são guiadas pela apresentação dos sintomas clínicos e pelas alterações nos sinais vitais. Frequência cardíaca (FC) e pressão arterial sistólica (PAS), isoladamente, nem sempre refletem com acurácia o início de quadros hipovolêmicos. Contudo, a combinação dos sinais vitais tradicionais (FC/PAS) origina o índice de choque (IC), que se postula ser indicador mais precoce de hipovolemia. Objetivo: A proposta deste estudo foi estabelecer a acurácia diagnóstica do IC para o diagnóstico inicial de hipovolemia decorrente de hemorragia, tanto em ambiente simulado, quanto em situações clínicas obstétricas. Método: Estudos transversais que incluíram dados de indivíduos adultos de qualquer idade ou sexo com suspeita de hemorragia, provenientes de estudos clínicos (obstétricos) ou simulados (doadores de sangue ou submetidos à LBNP – Low body negative pressure), que avaliaram a acurácia do IC e dos sinais vitais tradicionais (PA e FC) isolados no diagnóstico de hipovolemia foram incluídos no presente estudo. Valores considerados como hipovolêmicos foram IC > 0,7, FC > 100 bpm e/ou PAS < 100 mmHg. Obtiveram-se os estudos das seguintes bases de dados: CENTRAL, MEDLINE, EMBASE e LILACS, com os termos “shock index” e “hypovolemia” e suas variantes. Última pesquisa foi realizada em maio de 2016. A ferramenta QUADAS avaliou a qualidade metodológica. Metanálise proporcional foi realizada com variáveis dicotômicas e seus respectivos intervalos de confiança de 95%, considerando o efeito randômico. A heterogeneidade foi calculada por meio do I2. Resultados: A busca inicial identificou 121.648 títulos. Após seleção por títulos e resumos, obtiveram-se 101 artigos com prováveis critérios de inclusão na revisão. Entretanto, 87 estudos foram excluídos por serem revisões, cartas ao editor ou estudos fora do contexto. Desta forma, 14 estudos foram incluídos para análise, sendo 8 estudos de ensaios simulados e 6 de pacientes com quadro de hemorragia de natureza obstétrica; destes estudos, 6 foram incluídos na metanálise. O tamanho das amostras variou de 15 a 336 pacientes, com idade variando de 22 a 65 anos. Os resultados da metanálise mostraram que quando IC > 0,7 foi utilizado para detectar perda sanguínea nos pacientes simulados e obstétricos a proporção de detecção deste evento foi de 67% (intervalo de confiança 95%: 0,46 - 0,84), quando comparado à detecção de 25% (intervalo de confiança 95%: 0,12; 0,42) da PAS < 100 mm Hg (p < 0,05). Não houve diferença estatística entre IC e PAS em relação à FC > 100 bpm (proporção de detecção do evento = 27% (intervalo de confiança 95%: 0,07; 0,54). Conclusão: Esta revisão sistemática e metanálise proporcional sugere que o IC > 0,7 apresenta maior proporção na detecção inicial de hipovolemia causada por perda sanguínea em indivíduos submetidos a estudos simulados e em pacientes obstétricas, quando comparado à PAS isoladamente. Mais estudos são necessários para investigar se o IC é capaz de identificar maior proporção de casos de hipovolemia quando comparado à FC isoladamente. / Background: Screening and initial evaluation of patients with possible hypovolemia are guided by the presentation of symptoms and changes in vital signs. Heart rate (HR) and systolic blood pressure (SBP), alone do not always accurately reflect the onset of hypovolemic state. However, the combination of traditional vital signs (HR / SBP) gives rise to shock index (SI), which appears to be an more early indicator of hypovolemia. Aim: The purpose of this study was to establish the diagnostic accuracy of SI for the early diagnosis of hypovolemia due to hemorrhage, in a simulated environment and in obstetric clinical situations. Methods: Cross-sectional studies that included data from individuals adults of any age or sex with suspected hemorrhage from clinical (obstetric) or simulated (blood donor or Lower Body Negative Pressure) studies, who assessed the accuracy of the SI and the traditional vital signs (SBP and HR) isolated in the diagnosis of hypovolemia were included in the the present study. We considered as hypovolemic patients which achieved the following cut-off values: SI> 0.7, HR> 100 bpm, and / or SBP <100 mmHg. We obtained studies of the following databases: CENTRAL, MEDLINE, EMBASE and LILACS, with the terms "shock index" and "hypovolemia" and their variants. Last search was run in May 2016. QUADAS was the tool used to evaluate the methodological quality. Proportional metanalysis was performed with dichotomous variables and their respective 95% confidence intervals (CI), considering the random effect. The heterogeneity was calculated by means of I2. Results: The initial search identified 121,648 titles. After selection by titles and abstracts, we obtained 101 articles that match the inclusion criteria in the review. However, 87 studies were excluded because they were revisions, letters to the editor, or studies out of context or off-topic. In this way, 14 studies were included for analysis, being 8 simulated trial studies and 6 of patients with obstetric hemorrhage; of these studies, 6 were included in the metanalysis. Sample sizes ranged from 15 to 336 patients, ranging in age from 22 to 65 years. The results of the metanalysis showed that when SI> 0.7 was used to detect blood loss in simulated and obstetric patients, the proportion of detection of this event was 67% (95% CI = 0.46; 0.84), when compared to detection of 25% (95% CI = 0.12, 0.42) when SBP <100 mm Hg was used to detect hyvolemia (p <0.05). There was no statistically significant difference between SI or SBP in relation to HR> 100 bpm (event detection ratio = 27% (95% CI = 0.07; 0.54). Conclusion: This systematic review and proportion metanalysis suggests that SI> 0.7 has a higher proportion of early detection of hypovolemia caused by blood loss in subjects submitted to simulated studies and in obstetric patients when compared to SBP alone. More studies are needed to investigate these findings when compared to the detection of hypovolemia using HR.

Orientador: Antonio Fernando Ribeiro / Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas / Made available in DSpace on 2018-08-19T03:42:04Z (GMT). No. of bitstreams: 1 Franco_CarolineBuarque_M.pdf: 1016164 bytes, checksum: d2defa35883e9f73fc3f033e2ca1c3f1 (MD5) Previous issue date: 2011 / Resumo: Objetivo: A proposta de utilizar o método Pilates teve o objetivo de desenvolver um programa de exercícios, avaliando os efeitos no início e final do acompanhamento, coletando os seguintes dados: tolerância ao esforço físico pelo teste do degrau de 3 minutos (TD3); prova de função pulmonar (PFP); avaliação força muscular respiratória (FMR) pela pressão inspiratória máxima (PImáx) e pressão expiratória máxima (PEmáx) pela manovacuometria; qualidade de vida (QV) pelos questionários de qualidade de vida em fibrose cística (QFC); escore z de peso (kg), escore z de altura (m2) e escore z de IMC (kg/m2). Coleta dos valores em repouso e no final de cada sessão: saturação periférica de oxigênio (SpO2), frequência cardíaca (Fc), frequência respiratória (Fr), nível da dispnéia pela escala de Borg modificada. Método: estudo prospectivo descritivo analítico, casuística de 19 pacientes. A pesquisa foi realizada com os pacientes do Ambulatório de FC do Hospital de Clínicas (HC) da Universidade de Campinas (UNICAMP) e do Instituto da Criança (ICr) do HC da Faculdade de Medicina Universidade de São Paulo (FMUSP). O método foi aplicado em uma sessão semanal durante 4 meses. Resultados: A PImáx no grupo total apresentou aumento significativo (p<0,05 probabilidade do teste de Wilcoxon), a PEmáx demonstrou aumento significativo somente no grupo feminino (p=0,007). A PFP não apresentou diferenças no grupo total de pacientes (p>0,05). No TD3 pré-tratamento do grupo masculino, houve aumento significativo da frequência cardíaca (Fc) (p=0,043) e da escala de Borg (p=0,023). No pós-tratamento os sinais vitais permaneceram sem mudanças significativas. No TD3 pré-tratamento, o grupo feminino apresentou aumento significativo na Fc, frequência respiratória (Fr) e na escala de Borg (p<0,05). No pós-tratamento o TD3 deste grupo continuou com aumento significativo na Fc, Fr e na escala de Borg. Quanto as medidas de sinais vitais comparando o início e final de cada sessão, na 1ª sessão de Pilates o grupo total de pacientes,não apresentou mudanças na SpO2, Fc, Fr e na escala de Borg (p>0,05). Na 7ª sessão, no gênero masculino ocorreu aumento significativo da Fc e no grupo total de pacientes houve aumento significativo na escala de Borg. Na 16ª sessão apenas o grupo feminino apresentou aumento significativo na escala de Borg. Quanto ao escore z de peso e IMC, os pacientes não apresentaram mudanças, porém houve aumento significativo no escore z de altura apenas do grupo feminino (p=0,012). A avaliação da QV não demonstrou mudanças no QFC de crianças de 6 à 11 anos. No QFC dos pais/cuidadores de crianças de 6 à 13 anos houve aumento significativo no domínio respiratório. O QFC referente aos pacientes de 14 anos ou mais apresentou aumento significativo no domínio físico. Conclusões: O estudo evidenciou que a aplicação do Pilates foi eficaz no ganho da FMR; melhorias na tolerância física do grupo masculino pelo TD3; ganho no escore z de altura no grupo feminino. Quanto a QV do QFC dos pais/cuidadores de crianças de 6 à 13 anos, houve melhorias no domínio da condição respiratória e no QFC referente aos pacientes de 14 anos ou mais apresentou melhorias no domínio da condição física / Abstract: Objective: The proposal to use the Pilates method was to develop an exercise program, evaluating the effects at the beginning and end of follow-up by collecting the following data: the tolerance to exercise step test for 3 minutes (TD3) function test lung (PFP), respiratory muscle strength assessment (FMR) by maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP) by the manometer, quality of life (QOL) questionnaires for quality of life in cystic fibrosis (QFC), z-score Weight (kg), z score for height (m2) and z score of BMI (kg/m2). Collection of the values at rest and at the end of each session: peripheral oxygen saturation (SpO2), heart rate (HR), respiratory frequency (Fr), level of dyspnea by the Borg scale. Method: a prospective descriptive analytical sample of 19 patients. The survey was conducted with patients from the CF Clinic, Hospital de Clinicas (HC), Universidade de Campinas (UNICAMP) and the Instituto da Criança (Chr), HC, Faculdade de Medicina da Universidade de São Paulo (FMUSP). The method was applied to one session per week for four months. Results: MIP in the total group showed a significant increase (p<0.05 probability of the Wilcoxon test), MEP showed an increase only in the female group (p=0.007). The PFP did not show differences in the total group of patients (p>0.05). In TD3 pretreatment of the male group, there was increased heart rate (HR) (p=0.043) and Borg (p=0.023). In the post-treatment vital signs remained without significant changes. No TD3 pretreatment, the female group showed an increase in HR, respiratory frequency (Fr) and the Borg scale (p<0.05). In the post-treatment group continued TD3 this significant increase in HR, Fr and Borg scale. The measures vital signs comparing the beginning and end of each session, a session of Pilates the total group of patients showed no changes in SpO2, HR, Fr and Borg scale (p>0.05). During the 7th session, a significant increase of Fc in males and in the total group of patients showed a significant increase in Borg scale. In the 16th session only female group showed an increase in Borg scale. As for the z scores for weight and BMI, patients had no change, but there was an increase in height z scores in the female group (p=0.012). The assessment of QOL showed no changes in the QFC of children 6 to 11 years. In QFC parents/caregivers of children 6 to 13 years there was an increase in the field related respiratory and QFC in referring to patients 14 years or more, an increase in the physical realm. Conclusions: The study suggested that the use of Pilates has been effective in: gain of FMR, improvements in physical tolerance in male group, gain in height z scores in the female group. As for the QL QFC parents/caregivers of children 6 to 13 years there has been an improvement in respiratory status and QFC referring to patients 14 years or more improvements in physical condition / Mestrado / Saude da Criança e do Adolescente / Mestre em Saude da Criança e do Adolescente