The revolutionary advancements in the field of bioinformatics have opened new horizons in biological and pharmaceutical research. However, the existing bioinformatics tools are unable to meet the computational demands, due to the recent exponential growth in biological data. So there is a dire need to build future bioinformatics platforms incorporating modern parallel computation techniques. In this work, we investigate FPGA based acceleration of these applications, using High-Level Synthesis. High-Level Synthesis tools enable automatic translation of abstract specifications to the hardware design, considerably reducing the design efforts. However, the generation of an efficient hardware using these tools is often a challenge for the designers. Our research effort encompasses an exploration of the techniques and practices, that can lead to the generation of an efficient design from these high-level synthesis tools. We illustrate our methodology by accelerating a widely used application -- HMMER -- in bioinformatics community. HMMER is well-known for its compute-intensive kernels and data dependencies that lead to a sequential execution. We propose an original parallelization scheme based on rewriting of its mathematical formulation, followed by an in-depth exploration of hardware mapping techniques of these kernels, and finally show on-board acceleration results. Our research work demonstrates designing flexible hardware accelerators for bioinformatics applications, using design methodologies which are more efficient than the traditional ones, and where resulting designs are scalable enough to meet the future requirements.

No description available.

Hypothesis of our study is as follows: we assume that physical preparation of girls of the same age and their attitude towards physical education shall differ in different stages of their organism maturity. Goal of the study is to define a relation between physical preparation of girls of different ages and their attitude towards physical education and their sexual maturity. The research was performed in Vilnius Gerosios Vilties gymnasium in classes of 6-9 grade in the year 2004-2005. One hundred and forty five girls of basic health group of age 12-17 were participating in the research. Research methods applicable in the study were as follow: analysis and summary of literature recourses, testing, defining stage of sexual maturity, questionnaire filling, mathematical statistics, documentation and documentation received comparative analysis. We were examining weight, height and thorax size of schoolchildren. Tests of physical development were executed in school health care consulting room. Physical preparation of girls was being defined according to EUROFIT tests (300m running, 60m running, standing long jump; sitting and lying, trunk strength). The sexual maturity stage was defined by nurse in consulting room of Vilnius Secondary School of Gerosios Vilties according to methods by A.Stavickaja and D.Aron (in 1959), which was modified by V.Vlastovskis (in 1976). The comparative analysis of present results and results received 25 years ago was performed. ... [to full text]

Measurements with satellite and sounding rocket borne instruments contain important information on remote and local processes in regions containing matter in the plasma state. The characteristic features of the particle distributions can be used to explain the morphology and dynamics of the different plasma populations. Charged particles are lost from a region due to precipitation into the atmosphere, charge exchange processes, or convection to open magnetic field lines. The sources of the Earth’s magnetospheric plasma are mainly ionization and extraction of upper atmosphere constituents, and entry of solar wind plasma. The intensity and distribution of auroral precipitation is controlled in part by the conditions of the interplanetary magnetic field causing different levels of auroral activity. Acceleration of electrons and positive ions along auroral field lines play an important role in magnetospheric physics. Electric fields that are quasi-steady during particle transit times, as well as fluctuating fields, are important for our understanding of the behaviour of the plasma in the auroral region. High-resolution data from the Swedish Viking and the Swedish/German Freja satellites have increased our knowledge considerably about the interaction processes between different particle populations and between particles and wave fields. This thesis describes acceleration processes influencing both ions and electrons and is based on in-situ measurements in the auroral acceleration/heating region, with special emphasis on; processes at very high latitudes, the role of fluctuating electric fields in producing so called electron conics, and positive ion heating transverse to the geomagnetic field lines. / <p>Diss. (sammanfattning) Umeå : Umeå universitet, 1994, härtill 6 uppsatser.</p> / digitalisering@umu.se

The aim of this thesis is to determine the horse’s gait types using the acceleration values measured from the horse. A measurement was taken in Gävletravet, a total of five Nanotrak sensors were used, four on the different parts of the horse, and one on the hand of the horse’s driver, a car was driven parallel to the horse and the motions of the horse was recorded by a camera in order to synchronize with the data measured by the sensors, a total of four videos were recorded. The software to process the data was Matlab R2010b, and the methods to analyze them were Fast Fourier Transform (FFT), Short Time Fourier Transform (STFT), and Least Squares (LS). Different window functions were tried when applying the STFT, and the Hanning window was the best to smooth the curves, different window sizes (or data length) were also tried, the data length of 512 was found to be the most proper value. The methods for classification of horse’s gaits included amplitude, ratio, and LS. The method of amplitude worked well for the first three videos except for the last one, and performed better than the other two. The method of ratio was more reliable, but the results were not satisfactory. The method of LS gave bad results, so it was not trustworthy. More measurements and more analysis needed to be done in the future to find a proper way to automatic determine the horse’s gaits, and the use of modern technology will be very popular in other fields like animal science.

Driving simulators are used to conduct experiments on for example driver behavior, road design, and vehicle characteristics. The results of the experiments often depend on the traffic conditions. One example is the evaluation of cellular phones and how they affect driving behavior. It is clear that the ability to use phones when driving depends on traffic intensity and composition, and that realistic experiments in driving simulators therefore has to include surrounding traffic. This thesis describes a model that generates and simulates surrounding vehicles for a driving simulator. The proposed model generates a traffic stream, corresponding to a given target flow and simulates realistic interactions between vehicles. The model is built on established techniques for time-driven microscopic simulation of traffic and uses an approach of only simulating the closest neighborhood of the driving simulator vehicle. In our model this closest neighborhood is divided into one inner region and two outer regions. Vehicles in the inner region are simulated according to advanced behavioral models while vehicles in the outer regions are updated according to a less time-consuming model. The presented work includes a new framework for generating and simulating vehicles within a moving area. It also includes the development of enhanced models for car-following and overtaking and a simple mesoscopic traffic model. The developed model has been integrated and tested within the VTI Driving simulator III. A driving simulator experiment has been performed in order to check if the participants observe the behavior of the simulated vehicles as realistic or not. The results were promising but they also indicated that enhancements could be made. The model has also been validated on the number of vehicles that catches up with the driving simulator vehicle and vice versa. The agreement is good for active and passive catch-ups on rural roads and for passive catch-ups on freeways, but less good for active catch-ups on freeways.

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The purpose of this study is to develop probabilistic hazard maps for EskiSehir including &lsquo / Peak Ground Acceleration&rsquo / values for 10% probability of exceedance in 50-year and 100-year periods at different site classes. A seismotectonic map has been prepared in the Geographical Information Systems environment by compiling instrumental seismicity and neotectonic data for the study area. The seismic sources have been defined spatially in six areal zones, characterized by a commonly used recurrence law and a maximum magnitude value. Four attenuation relationships have been selected being one of them totaly developed from the strong-motion records of Turkey. After the implementation of a seismic hazard model by using SEISRISK software, the probabilistic seismic hazard curves and maps were developed based on the selected attenuation relationships, at &lsquo / rock&rsquo / and &lsquo / soil&rsquo / sites, with a probability of exceedance of 10% in 50-year and 100-year periods. At rock sites the highest levels of hazard were calculated based on the predictive relationship of Abrahamson and Silva (1996), whereas the lowest ones based on the one of Boore et al. (1996). On the other hand the highest hazard levels were determined at soil sites based on the attenuation relationship of Ambraseys et al. (1996), whereas the lowest ones based on the one of Boore et al. (1997). For EskiSehir, the peak ground acceleration values calculated based on attenuation relationship by Boore et al. (1997) were found to be applicable for 10% probability of exceedance in 50 and 100 years, taking into consideration the fact that a considerable portion of the city is founded over alluviums.

ABSTRACT QUANTIFICATION OF ACCELERATION CLAIMS: A SIMPLIFIED APPROACH Operating a successful business within the construction industry has become more difficult for companies as the profitability margins decreased considerably compared to previous years. Even, global economy has created an environment in which construction firms are enforced to bid projects at or below lowest profit levels. At the same time, owners are demanding more difficult projects without increasing the quality of contract documents. This has placed an added burden on the individual contractor to construct sophisticated projects. Under these circumstances, it is not surprising that the number of disputes within the construction industry continues to increase. Thus, contractors requested additional payments from the owners and the concept of claim and claim management developed. However, implementation of a well developed claim management process is crucial as the consequences and reimbursement depends on this process. The objective of this study is to discuss potential sources of disputes and types of claims in the construction industry by focusing on acceleration claims. Quantification methods for owner directed acceleration are discussed as well as required documentation and claim management strategies for preparation of acceleration claims. Two different methods, namely theoretical approach and simplified approach, are presented here and examined in detail mentioning their advantages and shortcomings. These methods are applied to two different real cases, one in Turkey and the other one is abroad in order to have a better understanding of these approaches. Furthermore, a computer program is developed to carry out the calculations that constitute the necessary steps of simplified quantification method. This study can be considered as a complete guide for young civil engineers about quantification and management of acceleration claims.

Despite the vast research on the effects of acceleration programs on student achievement there is little quantitative confirmation of the benefits of these programs and there is no research that investigates the effects of acceleration on students’ VCE Mathematics study scores. / This research attempts to fill this gap by considering four years of data provided by the Victorian Curriculum and Assessment Authority (VCAA) relating to achievement in mathematics. Acceleration in this study means the completion of the Year 12Mathematical Methods study during Year 11. The data constitutes experimental data for content acceleration and the results of students from schools without such acceleration programs provide the corresponding control data. However, the acceleration decision is not taken randomly by schools, so this data is only quasi-experimental in nature. The measures of mathematical achievement (Mathematical Methods and Specialist Mathematics study scores) are carefully audited, and are accepted as reliable and valid by the Victorian education system. Controlling for individual characteristics such as gender and prior knowledge, and allowing for moderation effects due to school sector (Government, Catholic and Independent) and school class setting (single-sex or coeducational), the effects of content acceleration are measured using multi-level modelling. / This study examines the effects of acceleration on the VCE Mathematics study scores of students who completed both Mathematical Methods (Units 3&4) and Specialist Mathematics (Units 3&4) in Victoria, over a four-year period (2001-2004). On average this involved 5341 students from 341 schools in each year with 829 students included in a content accelerated program. / The results suggest that content acceleration is beneficial, especially for students with higher prior knowledge scores. The quasi-experimental nature of the data means that a causal relationship between acceleration and students’ mathematical performance can be claimed. In particular, this study showed that the effect of acceleration on students’ Mathematical Methods (the Year 12 study taken in Year 11 by accelerated students) study score was not significant. However, the effect of acceleration on students’ Specialist Mathematics study scores was significant. Accelerated students performed, on average,2.7 points higher (on a 50 point scale) than equal ability age-peers who were not accelerated. Interestingly, for accelerated students who scored in the top 2% for their General Achievement Test, in the mathematics, science and technology component, their Specialist Mathematics study scores were on average, almost 5 points higher (on a 50point scale) than their equal ability age-peers. The statistical control of other factors means that these results can also be generalised to other states, other countries and, probably, to other subjects.